Sigma Nutrition Radio:  Health | Performance | Wel

Sigma Nutrition Radio: Health | Performance | Wel

Germany

SIGMA Nutrition Radio: a place where people interested in self-educating themselves in order to take control of their own health, body and performance can get access to honest, science-backed information and opinions from leading experts. Every week the show features deep-diving interviews with amazing guests with expertise in different areas related to nutrition, health, performance, mindset and living life to its fullest potential.

Episodes

SNR #176: Eric Trexler - Citrulline & Nitrate Supplements for Performance  

Eric Trexler is a PhD student at UNC Chapel Hill, under Dr. Abbie Smith-Ryan. He has a research focus on how exercise and nutrition affect metabolism, performance, and body composition. Eric comes from a background in natural bodybuilding, powerlifting, and strength coaching, and currently holds certifications in sports nutrition (CISSN) and strength and conditioning (CSCS). Eric completed his undergraduate degree at The Ohio State University, and his master’s degree at UNC Chapel Hill.
In This Episode We Discuss:

Proposed mechanisms of action of citrulline
Citrulline malate vs. L-citrulline
Nitric oxide "boosters"
Why arginine is ineffective
Dietary nitrates and nitrate supplementation via beetroot/pomegranate
What athletes might this work for?
Research on cordyceps supplementation for exercise performance

SNR #175: Prof. Klaas Westerterp - Metabolism, Energy Expenditure & Weight Regulation  

Klaas Westerterp is Professor of Human Energetics at Maastricht University. His field of expertise is energy metabolism, physical activity, food intake and body composition, and energy balance under controlled conditions and in daily life. He is member of the Editorial Board of the journal Nutrition and Metabolism (London), the European Journal of Applied Physiology, the European Journal of Clinical Nutrition, and Editor-in-Chief of the Proceedings of the Nutrition Society.

SNR #174: Jorn Trommelen – Carbohydrate Oxidation During Exercise & Pre-Sleep Protein  

Episode 174: Researcher from Maastrict University, Jorn Trommelen is on the show to discuss his research on the effect of glucose/fructose on carbohydrate oxidation during exercise and the effect of pre-sleep protein on muscle protein balance.
Jorn earned his MSc in Nutrition and Health with top honors at Wageningen University & Research Centre. He is now pursuing a PhD in Muscle Metabolism at Maastricht University, at one of the leading laboratories in that field.

His research focusses on protein ingestion to optimize post-exercise muscle protein synthesis. In addition, he investigates carbohydrate metabolism during and after exercise.

Jorn won several awards for his research including:

A Young Investigator Award at the European College of Sport Science Congress in 2015 The GSSI Sport Nutrition Award at the American College of Sports Medicine in 2016 The Gail E. Butterfield Nutrition Travel Award at the American College of Sports Medicine in 2016 A GSSI Nutrition Award at the European College of Sport Science Congress in 2016
SNR #173: PJ Nestler - Training Specificity, Fight Conditioning & Pre-/Post-Training Strategies  

Episode 173: Performance coach PJ Nestler discusses training approaches for combat sport athletes to increase their strength, speed and power so that it actually translates to improved performance in the ring/cage.
PJ is a human performance specialist with over a decade of experience preparing top athletes for competition, and a life mission to help athletes and coaches realize their true potential. Over the past ten years, PJ has trained dozens of athletes from the UFC, NFL, NHL and MLB. His passion for combat sports and commitment to excellence, has driven him to become a leader in combat sports performance training. He has worked extensively with over 100 fighters, including multiple Brazilian Jiu-Jitsu World Champions and Top 10 ranked UFC fighters
Outside of training top athletes, PJ is devoted to sharing his knowledge and experience, with the purpose of elevating the fitness profession.

SNR #172: Ben Esgro - Thoughts on Lifting, Obsession and Fitness  

Episode 172: Ben Esgro returns to give more philosophical thoughts on training, powerlifting, achievement and much more.
Ben is the founder and COO of De Novo Nutrition. The company has both consulting and supplement branches, based on objective science and ethical practice. Ben is a registered dietitian (RD), as well as having a Masters in Nutrition and Exercise Science (MS) from Marywood University. He has over 6 years experience of coaching and programming for individuals all the way from general population folks all the way up to elite competitors, such as IPF Worlds 2015 93kg silver medalist Layne Norton. In addition to being a highly-regarded coach, he is also an accomplished competitor as both a USBF Pro Qualified Natural Bodybuilder and an internationally qualified IPF powerlifter.

Corey Peacock, PhD – Physical Preparation, Conditioning and Recovery for Elite MMA Athletes  

Episode 171: Corey Peacock, PhD discusses how he implements science-based practices in the physical preparation of the elite MMA athletes he works with, including Anthony Johnson, Michael Chandler, Matt Mitrione and Rashad Evans.
Dr. Corey Peacock is currently serving a dual role as the Head Exercise Physiologist and Performance Coach for MMA’s the Blackzilians fight camp. In this role, he is responsible for contributing physiological evaluations, strength & conditioning, and injury prevention methodologies. His experience as both a Strength Coach and Sports Performance Researcher have allowed him to implement state of the art injury prevention technology and coaching techniques within the team. A former collegiate football player and coach, Corey graduated from Kent State University with a Ph.D. in Exercise Physiology, focusing his application on human performance.

He works closely with many Strength & Conditioning professionals from the NFL, NHL, MMA and NCAAF and is regarded as one of the top Performance Coaches and Sports Scientists in South Florida. Along with coaching, Dr. Peacock also works as a professor in the Department of Health and Human Performance at Nova Southeastern University. As a researcher, he has contributed multiple peer-reviewed publications integrating the fields of exercise physiology, athletic performance, and supplementation.

SNR #170: Aadam Ali - Challenging Biases, Nutrition Philosophy & Practical Experiments with Ketogenic Dieting  

Episode 170: Aadam Ali of Physiquinomics is on to discuss his personal diet experiements, what he learnt and some philosophies on nutrition and training.
Aadam writes fitness-related content over at his site Physiqonomics. He writes about his philosophies on nutrition, training and all things physique related. He also self-experiments with different approaches and reports the results. These have included periods of time eating various iterations of a ketogenic diet, employing extended fasts, using time-restricted feeding and more. He has also written content for various other reputable sites including Strengtheory. Aadam also works one-to-one with coaching clients who want to improve their physique.

SNR #169: Chad Macias - Cancer Metabolism & Caution Over Ketogenic Diet/Ketones  

Episode 169: Molecular physiologist Chad Macias, of the Institute for Human Kinetics, discusses some limitations of research, issues of misinterpretation and/or inaccurate communication related to research on cancer, nutritional ketosis and the press-pulse method.
Chad is currently pursuing post-graduate research in Molecular Oncology. Chad has spent over 19 years conducting research and developing protocols in cellular and molecular physiology. He is an adjunct faculty member at the University of San Diego, and has developed some of the most advanced blood lactate testing and intermittent hypoxia protocols in the world. He founded the Institute for Human Kinetics in 2011, where he works with many of the world’s top athletes. In addition, he was a two sport Olympic athlete. He also serves as the Human Performance Specialist at Navy Special Warfare developing programs to prepare Navy Seals for combat deployment though their Tactical Athlete Program. Chad also heads OPI’s Research Team and has the knowledge base to conduct medical and exercise physiology research in both humans and rodents.

SNR #168: Powerlifting Weight Classes, Cutting Weight & Long-Term Thinking - Sigma Team Discussion  

Episode 168: The Sigma coaching team sit down to discuss issues related to selecting a powerlifting weight class, progression over the long-term and the pros and cons of cutting weight.

 

SNR #167: Dom D'agostino, PhD - Traumatic Brain Injury, CTE & Implications for Combat Sport Athletes  

Episode 167: Dominic D'Agostino, PhD returns to the show to discuss issues related to traumatic brain injury (including CTE) and associations with contact sports such as boxing, MMA and American football.

Dominic D’Agostino, Ph.D.

Dr. D'agostino is an Assistant Professor at the College Of Medicine Molecular Pharmacology & Physiology at the University of South Florida. The primary focus of his laboratory is developing and testing metabolic-based therapies, including ketogenic diets, ketone esters, ketone supplements and metabolic-based drugs. His research also explores the use of these metabolic therapies for a broad range of disorders linked pathophysiologically to metabolic dysregulation, including seizures, neurological disorders, wound healing, muscle wasting and cancer. The laboratory uses in vivo and in vitro techniques to understand the physiological, cellular and molecular mechanism of metabolic therapies.

In This Episode We Discuss: Development of chronic TBI Chronic traumatic encephalopathy (CTE) and association with combat sports and American football Potential risk reduction strategies for combat sport athletes What's going on in the brain after injury? - GABA, glutamate, elctrolytes, etc. Substrate metabolism in the brain and neuro-inflammatory response after injury
SNR #166: Stephan Guyenet, PhD - The Neuroscience of Overeating & Regulation of Calorie Balance  

Episode 166: Stephan Guyenet, PhD discusses what drives us to overeat, factors affecting appetite regulation and calorie balance.
Stephan is an obesity researcher, neurobiologist, and author. In addition to his research, he enjoys synthesizing and communicating science for a general audience over at his hugely successful blog. Stephan has a BS. in biochemistry (University of Virginia) and a PhD in neurobiology (University of Washington). He recently published the fantastic book 'The Hungry Brain', which dives into the causes of obesity from the perspective of overeating and related brain chemistry.

SNR #165: Kevin Hall, PhD - Testing the Carbohydrate-Insulin Model & a Response to Gary Taubes  

Episode 165: Kevin Hall, PhD of the National Institutes of Health (NIH) is on the podcast to discuss his work examining the carbohydrate-insulin model of obesity and responds to recent comments on the issue by Gary Taubes.
Dr. Hall is a Senior Investigator in the Laboratory of Biological Modeling at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

Kevin's laboratory investigates how metabolism and the brain adapt in response to a variety of interventions to diet and physical actvity. They perform experiments in both humans and rodents to better understand the complex mechanisms regulating macronutrient metabolism, body composition, and energy expenditure. A unique aspect of the laboratory involves the development of mathematical models to quantitatively describe, explain, integrate, and predict our experimental results.

Over the past couple of years, Kevin has been the principal investigator on a couple of high-profile metabolic ward studies looking to examine: 1) the effect of restricting calories from fat vs. from carbohydrates, and 2) the hypothesis that ketogenic diets offer a metabolic advantage.

In This Episode We Discuss:

Defining the carbohydrate-insulin model of obesity
Scientific models and the principle of experimental falsification
Main predictions of the carbohydrate-insulin model
Examining the idea that ketogenic diets confer a metabolic advantage
Response to recent comments from Gary Taubes
The effect of weight loss on appetite

SNR #164: Dominic D'Agostino, PhD - Press-Pulse Model of Cancer Therapy, Ketones & Metabolic Drugs  

Episode 164: Dominic D'Agostino, PhD of the University of South Florida discusses his lab's research onto various treatment therapies for cancer including nutritional ketosis, hyperbaric oxygen therapy and metabolic drugs.
Dr. D'agostino is an Assistant Professor at the College Of Medicine Molecular Pharmacology & Physiology at the University of South Florida. The primary focus of his laboratory is developing and testing metabolic-based therapies, including ketogenic diets, ketone esters, ketone supplements and metabolic-based drugs. His research also explores the use of these metabolic therapies for a broad range of disorders linked pathophysiologically to metabolic dysregulation, including seizures, neurological disorders, wound healing, muscle wasting and cancer. The laboratory uses in vivo and in vitro techniques to understand the physiological, cellular and molecular mechanism of metabolic therapies.

In This Episode We Discuss:

Cancer as a metabolic disease Potential mechanisms of action for ketosis being a beneficial metabolic state in cancer patients Ketosis, calorie restriction, hyperbaric oxygen therapy and metabolic drugs as adjunct therapies in cancer treatment Possible future avenues of research What research needs to be done for this research to become seen more in front-line clinical practice Barriers to implementation
SNR #163: Mental Limitations to Making Progress  

Episode 163: Danny discusses some mental limitations to making progress. Namely they are: being unwilling to embrace the mundanely uncomfortable, an inability to invest in the long-term process and being unwilling to “do the work” without constant validation.

 

SNR #162: Andrew Chappell, PhD - Examining Contest Prep Strategies Followed by Natural Bodybuilders  

Episode 162: Andrew Chappell, PhD of Sheffield Hallam University is on the show to discuss preliminary data looking into different nutritional strategies followed by natural bodybuilders.

Dietary Strategies Of Elite Natural Bodybuilders - Chappell AJ & Simper T.,

The popularity of natural bodybuilding is increasing rapidly. Within the United Kingdom (UK) the British Natural Bodybuilding Federation (BNBF) runs seven regional qualifiers culminating in a UK finals. This cohort provides an excellent opportunity to study the dietary and training practices of an elite group of natural bodybuilders. In order to achieve the optimal physique for competition the athlete typically undertakes in a fat loss regime whilst attempting to maintain muscle mass normally accrued prior to the weight loss period. A combination of resistance training, cardiovascular exercise, calorie reduction, supplement regimes and peaking strategies are employed in order to obtain this physique. Although recommendations exist, these recommendations are not always based on bodybuilding populations and there is a paucity of applied research in this area. Here we report the results of a recent cross-sectional study investigating the preparation techniques of natural bodybuilding participant's competing at the BNBF finals. There was a tendency for successful bodybuilders to have a different macronutrient composition than unsuccessful bodybuilders. Specifically carbohydrate intake was higher over the duration of a pre-contest diet in successful bodybuilders. Implications for this will be discussed.

 

SNR 161: Rob Lipsett - Building a Physique, Staying on Track When Travelling & Lessons from Competing  

Episode 161: Dublin-based coach and fitness entrepreneur Rob Lipsett is on the show to discuss his journey, philosophies and work with clients.

Rob Lipsett is a personal trainer, physique competitor and fitness entrepreneur. Rob has built a loyal following based on giving insights into his own training and lifestyle, blended with handing out solid evidence-based information.

In This Episode We Discuss: Lessons learned from competing in natural physique competition Advice for those looking to build a physique naturally Reasons why people don't achieve their body composition goals How to determine whether you should bulk or cut Keeping on track with training and dieting whilst travelling

 

SNR 161: Rob Lipsett - Building a Physique, Staying on Track When Travelling & Lessons from Competing  

Episode 161: Dublin-based coach and fitness entrepreneur Rob Lipsett is on the show to discuss his journey, philosophies and work with clients.

 

SNR #160: Tools That Have Been Invaluable to My Life  

Episode 160: Danny discusses tools that have been invaluable to him in life across 5 categories: non-nutrition books, tracking, creation, living life and asking yourself questions.

SNR #159: Phil Graham - The Diabetic's Guide to Muscle, Fat Loss & Fitness  

Episode 159: Author of the Diabetic Muscle and Fitness Guide, Phil Graham, returns to the show to discuss how diabetics should eat and exercise if they want to gain muscle, lose fat or be healthy, without having their condition hold them back.

SNR #158: Alex Ritson - Adaptive Thermogenesis, Thrifty Genes & Hedonic Eating  

Episode 158: Alex Ritson dives into the metabolic adaptations that occur with dieting (and overfeeding), the implications of this for the dieter and how this can explain the differences between individuals in their response to a diet.

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