Episodi
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Vincent travels to the University of Texas in Austin to speak with speak with Jason McLellan about his career and his research on the SARS-CoV-2 spike protein, including the effect of adding two proline residues, its effect on other viral spike glycoproteins, and general approaches to vaccine design.
Hosts: Vincent Racaniello and Rich Condit
Guest: Jason McLellan
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Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Become a member of ASV (asv.org) The New City by Dickson Despommier Prefusion-stabilized SARS-CoV-2 spikes (Science) Structure-based vaccine design (Curr Opin Immunol) Prefusion-stabilized SARS-CoV-2 S2-only antigen (Nat Comm) Stabilized coronavirus spike stem elicits broadly protective antibody (Cell Rep) Timestamps by Jolene. Thanks!Intro music is by Ronald Jenkees
Send your virology questions and comments to [email protected]
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In his weekly clinical update, Dr. Griffin reviews recent statistics on the circulation of measles and influenza before addressing Vincentâs comment on measles inclusion in the clinical respiratory PCR panel, the latest statistics on influenza and COVID-19 circulation, if inflammatory cytokines and anti-viral antibody function synergistically, if administration of peptide agonists of the glucagon-like or sodium-glucose pump can reduce disease severity, restates the guidelines for spring administration of COVID vaccines boosters, discusses the emergency use application of a pre-exposure prophylactic. revised guidelines for how to treat respiratory viral infection guidelines by the CDC, continues to dispel the myth of viral rebound, revised guidelines for SARS-CoV-2 treatment and how to treat respiratory viral infections, when to use steroids and the benefits of convalescent plasma, what do when healthcare workers succumb to SARS-CoV-2 infection, if remdesivir or paxlovid can reduce cardiovascular adverse events and the first finding of the two-year longitudinal study on long COVID. For more information about this body of work, listen to TWiV 1088.
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Links for this episode Measles tracking (CDC) What happens when measles is included in commercial syndromic PCR panels (MMWR) Influenza/flu surveillance (CDC) Influenza on the Texas ranch (Statnews) Sequence analysis of highly pathogenic avian influenza from Texas (CDC) Influenza/flu map (CDC) COVID-19 hospital admissions (CDC) COVID-19 national trend (CDC) COVID-19 wastewater testing (biobot) Variant tracker (CDC) Variant hospital admissions (CDC) Can inflammatory cytokines and antibodies play nicely to prevent COVID-19 mortality (IJID) Association of GLP-1RA and SGLT-2i to modulate COVID-19 severity (Diabetes Therapy) Spring COVID-19 booster recommendations (CIDRAP) Older adult spring booster available (CDC) Advisory committee for immunization practices spring 2024 COVID-19 boosters (CDC) EUA for pemgarda (FDA) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (IDSociety) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) What do when your heathcare provider is infected with SARS-CoV-2 (CDC) Managing healthcare staffing shortages (CDC) Steroids,dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Remdesivir and cardiac adverse events in hospitalized patients (CID) Long COVID evidence based review TWiV shout out (TWiV 1088) Longitudinal study reveals long COVID symptom peaks and nadirs (OFID) Paxlovid lowers risk of cardiovascular disease in COVID-19 patients with autoimmune disease (BMC Medicine) Contribute to our ASTMH fundraiser at PWB Letters read on TWiV 1102 Dr. Griffinâs COVID treatment summary (pdf) Timestamps by Jolene. Thanks!Intro music is by Ronald Jenkees
Send your questions for Dr. Griffin to [email protected]
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Episodi mancanti?
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Paul Offit joins TWiV to discuss his latest book, âTell Me When Itâs Overâ, an insiderâs guide to deciphering COVID myths and navigating our post-pandemic world.
Hosts: Vincent Racaniello, Dickson Despommier, and Brianne Barker
Guest: Paul Offit
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Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Become a member of ASV (asv.org) The New City by Dickson Despommier Tell Me When Itâs Over by Paul Offit Navigating the U.S. Immigration System (webinar) Classifying Viral Subspecies (Workshop) Options XII for the Control of Influenza (Meeting) Letters read on TWiV 1101 Timestamps by Jolene. Thanks! Weekly PicksDickson â Astronomers Unveil Strong Magnetic Fields Spiraling at the Edge of Milky Wayâs Central Black Hole
Brianne â Inside the AI Competition That Decoded an Ancient Herculaneum Scroll
Vincent â biotech.symposium on InstagramIntro music is by Ronald Jenkees
Send your virology questions and comments to [email protected]
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In his weekly clinical update, Dr. Griffin reviews recent statistics on the circulation of measles influenza and SARS-CoV-2, before discussing the development of new monoclonal antibody therapy, if vaccines and antivial drugs can used effectively together. revised guidelines for how to treat respiratory viral infection guidelines by the CDC, continues to dispel the myth of viral rebound including that after administration of the âoral remdesivirâ, revised guidelines SARS-CoV-2 treatment and how to treat respiratory viral infections, when to use steroids and the benefits of convalescent plasma, what do when healthcare workers succumb to SARS-CoV-2 infection, if one can predict the loss infectivity of healthcare workers with mild COVID-19 disease and the dynamics of household transmission of the virus in children.
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Links for this episode Measles tracking (CDC) Influenza/flu surveillance (CDC) Influenza/flu map (CDC) COVID-19 hospital admissions (CDC) COVID-19 national trend (CDC) COVID-19 wastewater testing (biobot) Variant tracker (CDC) Variant hospital admissions (CDC) What new monoclonal antibody therapy? (FDA) A New pre-exposure prophylaxis for COVID-19? (Invivyd) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Really COVID-19 rebound after Nirmatrelvir-ritonavir treatment? (JAMA Network Open) Can vaccines and antiviral be effective for COVID-19 together (International Journal of Infectious Diseases) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (IDSociety) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) What do when your heathcare provider is infected with SARS-CoV-2 (CDC) Managing healthcare staffing shortages (CDC) Can loss of infectivity among healthcare works with mild and recurrent COVID-19 be predicted (CID) Household transmission dynamics in children with asymptomatic infection (CID) Steroids,dexamethasone at the right time (OFID)Anticoagulation guidelines (hematology.org) Contribute to our ASTMH fundraiser at PWB Letters read on TWiV 1098 Dr. Griffinâs COVID treatment summary (pdf) Timestamps by Jolene. Thanks!Intro music is by Ronald Jenkees
Send your questions for Dr. Griffin to [email protected]
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Vincent travels to the University of Heidelberg to speak with Volker Lohmann about his career and the research of his laboratory on hepatitis C virus, hepatitis A virus, and norovirus.
Host: Vincent Racaniello
Guests: Volker Lohmann
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Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Become a member of ASV (asv.org) The New City by Dickson Despommier HCV human challenge studies (Lancet Gastro Hepatol) Comparison of HCV and HAV infections (J Hepatol) HCV cell culture systems (J Med Chem)Intro music is by Ronald Jenkees
Send your virology questions and comments to [email protected]
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In his weekly clinical update, Dr. Griffin deep dives into recent domestic and global measles and mpox outbreaks, before reviewing recent statistics on the circulation of respiratory syncytial virus, influenza and SARS-CoV-2, discussing revised guidelines for how to treat respiratory viral infection guidelines by the CDC, revised guidelines SARS-CoV-2 treatment and how to treat respiratory viral infections, continues to dispel the myth of viral rebound, when to use steroids and the benefits of convalescent plasma, what do when healthcare workers succumb to SARS-CoV-2 infection, how much oxygen is necessary for effective treatment of severe disease, how COVID-19 effects the cardiovascular system of children and adolescents with long COVID and how iron metabolism may be altered during long COVID.
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Links for this episode Measles tracking (CDC) Measles in Cook County (MMWR) Gaps in measles vaccination drives viral surges (Infectious Disease Advisor) Misinformation impacts public health? Seriously? (ID Society) CDC alert for global and domestic measles cases and outbreaks (CDC) Mpox in Kamituga associated with outbreak in DRB (Eurosurviellance) Mpox in US, 2023 (MMWR) Mpox in DRC, 2024 (reliefweb) CDC guidance for respiratory diseases, COVID antiviral & emergence of clade I mpox (ID Society) ~5% of infected dead from mpox (CIDRAP) First cases of mpox in Republic of Congo (AP News) Respiratory disease surveillance (CDC) RSV surveillance (CDC) RSV national trend (CDC) Influenza/flu surveillance (CDC) Influenza/flu map (CDC) COVID-19 hospital admissions (CDC) COVID-19 national trend (CDC) COVID-19 wastewater testing (biobot) Variant tracker (CDC) Variant hospital admissions (CDC) Multisystem inflammatory syndrome in children 2023 (MMWR) Guidance for COVID-19 in children and adolescents (JPIDS) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Molnupiravir safety and efficacy (JMV) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) What do when your heathcare provider is infected with SARS-CoV-2 (CDC) Managing healthcare staffing shortages (CDC) Steroids,dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) High/low oxygenation target (JAMA) How much oxygen is needed (JAMA) Orthostatic intolerance in long COVID and healthy volunteers (JMV) Autonomic cardiac function in children and adolescents with long COVID (European Journal of Pediatrics) Long COVID iron dysregulation and inflammatory stress erythropoiesis (Nat Imm) Contribute to our ASTMH fundraiser at PWB Letters read on TWiV 1098 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene. Thanks!Intro music is by Ronald Jenkees
Send your questions for Dr. Griffin to [email protected]
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Vincent travels to the fifth Giant Virus Meeting in Tegernsee, Germany and speaks with Sheree Yau and Victoria Queiroz about their research on picoeukaryotes (tiny algal cells) and their viruses, pithoviruses, and an educational kit for virology classes.
Host: Vincent Racaniello
Guests: Sheree Yau and Victoria Queiroz
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Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Become a member of ASV (asv.org) The New City by Dickson Despommier 8:16 Virophage control of antarctic algal host-virus dynamics (PNAS) Timestamps by Jolene. Thanks! Virus-host coexistence in phytoplankton through the genomic lens (Sci Adv) Two groups of pithoviruses (J Virol) Educational toolkit for virology classes (J Virol)Intro music is by Ronald Jenkees
Send your virology questions and comments to [email protected]
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In his weekly clinical update, Dr. Griffin highlights measles outbreaks throughout the continental US, reviews recent statistics on the circulation of respiratory syncytial virus, influenza and SARS-CoV-2 before discussing if vaccination protected children from the development of long COVID or cardiovascular diseases associated with virus infection, revised guidelines SARS-CoV-2 treatment and how to treat respiratory viral infections, continues to dispel the myth of viral rebound, when to use steroids and the benefits of convalescent plasma, how COVID-19 effects the autonomic nervous system, and if nirmatrelvir-ritonavir protects against adverse cardiovascular effects following SARS-CoV-2 infection.
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Links for this episode Measles everywhere (CDC) Respiratory disease surveillance (CDC) RSV surveillance (CDC) RSV national trend (CDC) Estimating niresevimab effectiveness for infants (MMWR) More than 100 children died of influenza (NBS News) Influenza/flu surveillance (CDC) Influenza/flu map (CDC) COVID-19 hospital admissions (CDC) COVID-19 national trend (CDC) COVID-19 wastewater testing (biobot) Variant tracker (CDC) Variant hospital admissions (CDC) Did the vaccine protect children against Long COVID (Pediatrics) Did COVID-19 vaccination impact cardiovascular diseases? (Nat Comm) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (IDSociety) Updated respiratory infection guidelines (CDC) What do when your heathcare provider is infected with SARS-CoV-2 (CDC) Managing healthcare staffing shortages (CDC) Steroids,dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Long COVID trial for autonomic nervous system dysfunction (NIH) Nirmatrelvir-ritonavir impact on myocardial injury and long-term cardiovascular outcomes in COVID-19 hospitalized patients (Cardiovascular Drugs and Therapy) Contribute to our ASTMH fundraiser at PWB Letters read on TWiV 1096 Dr. Griffinâs COVID treatment summary (pdf) Timestamps by Jolene. Thanks!Intro music is by Ronald Jenkees
Send your questions for Dr. Griffin to [email protected]
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TWiV reviews heterosexual transmission of clade I Mpox virus, continued circulation of oropouche virus in South America, herpesviruses in South American fur seals and sea lions, sex-specific differences in physiological responses to SARS-CoV-2 infection, underdetected dispersal and extensive local transmission drove the 2022 mpox epidemic, and a humanized mouse model for adenovirus-associated virus gene therapy.
Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Angela Mingarelli
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Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Become a member of ASV (asv.org) The New City by Dickson Despommier Heterosexual transmission of clade I Mpox virus (Emerg Inf Dis) Continued circulation of oropouche virus (PAHO and WHO) Herpesviruses in fur seals and sea lions (PLoS One) Sex-specific effects of SARS-CoV-2 infection (PLoS One) Drivers of 2022 Mpox virus epidemic (Cell) How AAV gene transfer works (YouTube) Humanized mouse model for AAV gene therapy (Nat Comm) Timestamps by Jolene. Thanks! Weekly PicksDickson â Baden Powell â Manha de Carneval
Listener Pick
Angela â Upcoming Health & Fitness podcast from MicrobeTV
Rich â Mark Smith Photography
Alan â OpenVertebrate (and Science article on it)
Vincent â Veterinary apparel for the veterinary nerdAnne â Why Reed Jobs is betting on cancer innovations
Intro music is by Ronald Jenkees
Send your virology questions and comments to [email protected]
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In his weekly clinical update, Dr. Griffin reviews recent statistics on the circulation of respiratory syncytial virus, influenza and SARS-CoV-2 before discussing revised guidelines for how to treat respiratory viral infection guidelines by the CDC, effectiveness of the new SARS-CoV-2 vaccines and the combination of vaccination and antiviral therapy against the development of disease, continues to dispel the myth of viral rebound, how to pay for paxlovid, the lack of evidence supporting ivermectin as an antiviral drug, when to use steroids and the benefits of convalescent plasma, how COVID-19 affects cognitive function and the effect of long COVID and how healthcare works have difficulty making the proper diagnosis for long COVID even using a questionnaire.
Subscribe (free): Apple Podcasts, Google Podcasts, RSS, emailBecome a patron of TWiV!
Links for this episode Respiratory disease surveillance (CDC) RSV surveillance (CDC) RSV national trend (CDC) Influenza/flu surveillance (CDC) Influenza/flu map (CDC) COVID-19 hospital admissions (CDC) COVID-19 national trend (CDC) COVID-19 wastewater testing (biobot) Variant tracker (CDC) Variant hospital admissions (CDC) What to do when you are sick with a respiratory virus (CDC) Basis for respiratory virus guidance (CDC) Effectiveness of updated COVID-19 vaccines (MMWR) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Synergy or additive protection with vaccination and oral antivirals (CID) To rebound or to not rebound (MMWR) Know your COVID-19 tools (ESMED) How to pay for Paxlovid (PAXCESS) Molnupiravir safety and efficacy (JMV) Still talking about Ivermectin? (Journal of Infection) Convalescent plasma recommendation for immunocompromised (IDSociety) Steroids,dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Cognition and memory after COVID-19 (NEJM) Loss of IQ after SARS-CoV-2 infection (CIDRAP) Really, more evidence for long COVID and impaired cognition (NEJM) Memory assessment before and after COVID-19 (NEJM) Please complete this memory questionnaire (Community hyperbaric) Impact of long-term COVID-19 on workers in healthcare settings (PLoS One) Healthcare workers have difficulty assessing long COVID (CIDRAP) Contribute to our ASTMH fundraiser at PWB Letters read on TWiV 1094 Dr. Griffinâs COVID treatment summary (pdf) Timestamps by Jolene. Thanks!Intro music is by Ronald Jenkees
Send your questions for Dr. Griffin to [email protected]
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TWiV discusses effectiveness of this seasonâs flu vaccine, efficacy of Pfizer RSV vaccine, nOPV2 in the US, dengue in Peru, measles in Michigan and Indiana, how coordinated inflammatory responses dictate control of Marburg virus by reservoir bats, and tRNA acquisition in phages driven by degradation of host translational machinery.
Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, Brianne Barker, and Jolene Ramsey
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Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Become a member of ASV (asv.org) The New City by Dickson Despommier Effectiveness of flu vaccine (MMWR, Eurosurveill) Efficacy of Pfizer RSV vaccine (Pfizer) Understanding six types of vaccine technologies (Pfizer) nOPV in US? (CDC) Dengue in Peru (Peruvian State) Measles in Michigan and Indiana Marburg virus control by reservoir bats (Nat Commun) tRNA acquisition by phages (Cell) Viruses of Microbes 2024 Timestamps by Jolene. Thanks! Weekly PicksBrianne â The reappearance of Lake Manly
Listener Picks
Kathy â âPractical Playbook for Addressing Health Misinformationâ
Rich â Making It So: A Memoir by Patrick Stewart
Jolene â Thinking Like a Phage by Merry Youle
Vincent â The Science of Leap YearBlog design â Anthony Fauci will reflect on his long government career in âOn Call,â to be published in June
Peter â Republican warns of vaccines being slipped into vegetables: âA polio vaccine in thereâIntro music is by Ronald Jenkees
Send your virology questions and comments to [email protected]
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In his weekly clinical update, Dr. Griffin reviews recent statistics on the circulation of respiratory syncytial virus, influenza and SARS-CoV-2 before discussing new vaccine guidelines released by the advisory committee on immunization practices, and reviews the CDC guidelines for quarantine/ isolation following SARS-CoV-2 infection, continues to dispel the myth of viral rebound, how to pay for paxlovid, when to use steroids and the benefits of convalescent plasma, the role of IFN-g in long COVID, if the brain-blood-barrier is compromised in long COVID, meaning of persistent community SARS-CoV-2 RNA findings, and the effects of hyperbaric oxygen on post COVID neurocognition.
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Links for this episode Respiratory disease surveillance (CDC) RSV surveillance (CDC) RSV national trend (CDC) RSV vaccination stats (CIDRAP) Influenza/flu surveillance (CDC) Influenza/flu map (CDC) COVID-19 hospital admissions (CDC) COVID-19 national trend (CDC) COVID-19 wastewater testing (biobot) Variant tracker (CDC) Variant hospital admissions (CDC) ACIP COVID vaccination for seniors recommendations (CIDRAP) Additional vaccine doses for older adults (CDC) Evidence based advice from the ACIP (CDC) State mandates did NOT influence primary vaccination rates only boosters (PNAS) No nOPV2? (CDC) CDC Quarantine guidelines (CDC) To rebound or to not rebound (MMWR) Know your COVID-19 tools (ESMED) How to pay for Paxlovid (PAXCESS) Molnupiravir safety and efficacy (JMV) Molunpiravir plus antibody therapy for at-risk outpatients (Nat Comm) Convalescent plasma recommendation for immunocompromised (IDSociety) Steroids, dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Spontaneous release of IFN-g in Long COVID (Science Advances) Blood-brain-barrier compromise in long COVID associated cognitive impairment (Nat Neuroscience) Persistent community SARS-CoV-2 RNA (Nature) Hyberbaric oxygen therapy improves post COVID neurocognition (Scientific Reports) Medical study questionnaire, the SHORT form (Brandeis) Long term effects of hyperbaric oxygen post COVID (Scientific Reports) Contribute to our ASTMH fundraiser at PWB Letters read on TWiV 1092 Dr. Griffinâs COVID treatment summary (pdf) Timestamps by Jolene. Thanks!Intro music is by Ronald Jenkees
Send your questions for Dr. Griffin to [email protected]
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TWiV reviews resurgence of Lassa fever in West Africa, at least 3 paralytic cases of cVDPV2 in Zimbabwe, CWD from eating prion-laden plants, measles in New Orleans and Broward County Florida, failure of Florida Surgeon General to support vaccination, a measles variant in Switzerland, SARS-CoV-2 persistent infections, leaky blood-brain-barrier for long COVID brain fog, West Nile virus transmitted among mosquitoes by the excreta, and viroid-like colonists of human microbiomes.
Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit and Kathy Spindler
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Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Become a member of ASV (asv.org) Research assistant position in Rosenfeld Lab CBER/FDA (pdf) The New City by Dickson Despommier Viruses of Microbes 2024 Resurgence of Lassa fever (Science) cVDPV2 in Zimbabwe (UNICEF) CWD from eating plants (CIDRAP) Measles in New Orleans (LA Dept Health) SARS-CoV-2 persistent infections (Nature) Leaky BBB for brain fog of long COVID (Nat Neurosci) Measles in Broward County FL (7 News) Failure of FL Surgeon General to support vaccination (X) Measles variant (Eurosurveillance) West Nile virus transmitted among mosquitos by excreta (bioRxiv) Mosquito life cycle (YouTube) Viroid-like colonists of human microbiomes (bioRxiv) Letters read on TWiV 1091 Timestamps by Jolene. Thanks! Weekly PicksDickson â Sustainable energy in America 2024 factbook
Kathy â Life Magnified USPS stamps
Rich â âHow plants communicate with each other when in dangerâ by Kasha Patel (Original Nature Communications article)
Alan â A Sargasso Sea of Space card game.
Vincent â Tell Me When Itâs Over by Paul OffitIntro music is by Ronald Jenkees
Send your virology questions and comments to [email protected]
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In his weekly clinical update, Dr. Griffin reviews recent statistics on the circulation of respiratory syncytial virus before discussing uptake of the RSV vaccine Abrysvo or the monoclonal anti-RSV antibody nirsevimab to prevent severe disease following RSV infection in infants 8 months or younger before going over this weekâs influenza virus and SARS-CoV-2 virus statistics, including all circulating variants in the US, examines if self-testing is more accurate than clinician administered Binax rapid diagnostic tests for SARS-CoV-2 infection, if N95 masks need a yearly fitting, how SARS-CoV-2 vaccination impacts the prevalence of long COVID, reviews the CDC guidelines for quarantine/ isolation following SARS-CoV-2 infection, continues to dispel the myth of viral rebound, how to pay for paxlovid, when to use steroids and the benefits of convalescent plasma, why determining the exact number of long COVID incidences is challenging, how the incidence and predictors for fatiguing illness following SARS-CoV-2 infection may used to reenforce the need for public health actions to prevent virus infection and the risks of respiratory pathologies including lung cancer associate with SARS-C0V-2 infection.
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Links for this episode Respiratory disease surveillance (CDC) RSV surveillance (CDC) RSV national trend (CDC) RSV vaccination stats (CIDRAP) Abrysvo vaccine stats (Axios) RSV vaccination dashboard (CDC) Influenza/flu surveillance (CDC) Influenza/flu map (CDC) COVID-19 hospital admissions (CDC) COVID-19 national trend (CDC) COVID-19 wastewater testing (biobot) Variant tracker (CDC) Variant hospital admissions (CDC) Who is more accurate the clinician or the self for BinaxNow rapid testing (ASM Spectrum) Annual N95 fitting (Infection Control and Hospital Epidemiology) How vaccination impacts long COVID prevalence (Annals of Epidemiology) CDC Quarantine guidelines (CDC) To rebound or to not rebound (MMWR) Know your COVID-19 tools (ESMED) How to pay for Paxlovid (PAXCESS) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (IDSociety) Steroids, dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Long COVID in adults (MMWR) Estimating and predicting fatiguing illness after SARS-CoV-2 infection (EIS) Long term risks of respiratory disease following SARS-CoV-2 infection (eClinical Medicine) Contribute to our ASTMH fundraiser at PWB Letters read on TWiV 1080 Dr. Griffinâs COVID treatment summary (pdf) Timestamps by Jolene. Thanks!Intro music is by Ronald Jenkees
Send your questions for Dr. Griffin to [email protected]
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TWiV reviews a fatal Alaskapox case, MERS in Kenya, diagnostic tests for Nipah and Lassa diseases, HPV vaccination rates in the US, cases of measles in Arizona and Minnesota, hepatitis C virus-derived RNA circles in infected cells, and prevention of respiratory virus transmission by resident memory CD8+ T cells.
Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Brianne Barker
Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email
Become a patron of TWiV!
Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Become a member of ASV (asv.org) Research assistant position in Rosenfeld Lab CBER/FDA (pdf) The New City by Dickson Despommier Viruses of Microbes 2024 Fatal case of Alaskapox (AK Beacon) MERS in Kenya (Emerg Inf Dis) Diagnostic tests for Nipah and Lassa (CEPI) Measles in Arizona and Minnesota HCV-derived circular RNAs (PNAS) Resident memory CD8 T cells prevent respiratory virus transmission (Nature) Letters read on TWiV 1089 1:24:33 Timestamps by Jolene. Thanks! Weekly PicksDickson â Visualizing Science: Illustration and Beyond
Brianne â Vaccination from the Misinformation Virus and Invisible Corps
Alan â Preventing needlephobia in kids
Vincent â Two new Djs I discovered Rosana Nun and Sunset CartelIntro music is by Ronald Jenkees
Send your virology questions and comments to [email protected]
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In his weekly clinical update, Dr. Griffin discusses the use of monoclonal antibody therapy to prevent RSV hospitalization of infants and use of GSKâs RSV vaccine Arexy to prevent severe disease following RSV infection in adults between 50-59 years before he reviews recent statistics on the circulation of respiratory syncytial virus, influenza virus and SARS-CoV-2 virus, including all circulating variants in the US, discusses if how the influenza vaccine is manufactured can reprogram the antibody response, cardiovascular consequences of influenza infection, mortality of chikungunya virus infection, if an alternative vaccination schedule impacts the anti-SARS-CoV-2 immune response, dispels the myth that increased mortality correlated with the first vaccine dose, continues to dispel the myth of viral rebound, how to pay for paxlovid, when to use steroids and the benefits of convalescent plasma, how manage long COVID including prevent burnout and compassion fatigue of caring for long COVID patients, whether the CDC or WHO definition of long COVID is beneficial or the use of directed questions, baselines test and listening to the patient tell their story are beneficial in making a long COVID diagnosis.
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Links for this episode Nirsevimab immunoprophylaxis to prevent RSV hospitalization (Eurosurveillance.) Arexvy given Priority Review in US for the prevention of RSV disease in adults aged 50-59 (GSK) Respiratory disease surveillance (CDC) RSV surveillance (CDC) RSV national trend (CDC) Can antibodies be redirected from egg adapted epitopes using recombinant or cell cultured based influenza vaccines (Nat) Can influenza infection lead to cardiovascular events (JID) Risk of death after chikungunya infection and disease (Lancet) Influenza/flu surveillance (CDC) Influenza/flu map (CDC) COVID-19 hospital admissions (CDC) COVID-19 national trend (CDC) COVID-19 wastewater testing (biobot) Variant tracker (CDC) Variant hospital admissions (CDC) Alternative intervals between vaccine doses (Nat Comm) Early mortality after first vaccination dose (CID) CDC Quarantine guidelines (CDC) To rebound or to not rebound (MMWR) Know your COVID-19 tools (ESMED) How to pay for Paxlovid (PAXCESS) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (IDSociety) Steroids, dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Burnout compassion fatigue Long COVID (OFID) Scoring PASC (JAMA) What is your definition of the Long COVID (WHO) Contribute to our ASTMH fundraiser at PWB Letters read on TWiV 1088 Dr. Griffinâs COVID treatment summary (pdf) Timestamps by Jolene. Thanks!Intro music is by Ronald Jenkees
Send your questions for Dr. Griffin to [email protected]
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TWiV reviews rhinovirus complications in infants, a new influenza antiviral drug, Oropouche fever in Brazil, measles in Maryland and Ohio, effect of eliminating non-medical vaccine exemptions in NY, foot-and-mouth disease in Europe, severe primary and secondary dengue infections, and therapeutic mitigation of measles-like immune amnesia and exacerbated disease after prior respiratory virus infections.
Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Angela Mingarelli
Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email
Become a patron of TWiV!
Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Become a member of ASV (asv.org) Research assistant position in Rosenfeld Lab CBER/FDA (pdf) The New City by Dickson Despommier Viruses of Microbes 2024 Infant rhinovirus bronchiolitis contribution to hospital bed and vent use (JAMA Net Open) Onradivir new influenza antiviral (Lancet) Oropouche fever in Brazil (PAHO) Maryland and Ohio measles Repealing school vaccination exemptions (JAMA New Open) Increases risk of FMDV entry into Europe (pig333) Severe primary and secondary dengue (Nat Med) Mitigation of measles immune amnesia and exacerbated disease (Nat Comm) Letters read on TWiV 1087 Timestamps by Jolene. Thanks! Weekly PicksDickson â For Your Processing Pleasure: The Sharpest Pictures of Jupiterâs Volcanic Moon Io in a Generation
Angela â Whale Scientists
Rich â Benefit-risk assessment of vaccines; The Brighton collaboration standardized module for vaccine benefit-risk assessment; Vaccine adverse events: causal or coincidental?; Austin area Singing Valentines
Vincent â International Day of Women and Girls in Science, 11 FebruaryIntro music is by Ronald Jenkees
Send your virology questions and comments to [email protected]
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In his weekly clinical update, Dr. Griffin discusses the how the pandemic influenced the healthcare job market and why people conceal their infectious diseases before he reviews most recent statistics on the circulation of respiratory syncytial virus, influenza virus and SARS-CoV-2 virus, including all circulating variants in the US, discusses if susceptibility and disease severity are inheritable traits, if vaccination during pregnancy protects neonates or leads to adverse effects, the effectiveness of a monovalent XBB.1.5 against disease resulting from infection with Omicron variants, whether vaccination in the same or opposite arms effect antibody protection, continues to dispel the myth of viral rebound, how to pay for paxlovid, when to use steroids and the benefits of convalescent plasma, how SARS-CoV-2 infection may alter oneâs sleep patterns, what the health and economic burdens of mild disease are, and if there are predictors for recovery from fatigue and cognitive deficits following SARS-CoV-2 infection.
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Links for this episode Do you want a job in healthcare? (JAMA) Why people donât tell the truth about infectious diseases (Psychological Science) Respiratory disease surveillance (CDC) RSV surveillance (CDC) RSV national trend (CDC) Influenza/flu surveillance (CDC) Influenza/flu map (CDC) COVID-19 hospital admissions (CDC) COVID-19 national trend (CDC) COVID-19 wastewater testing (biobot) Variant tracker (CDC) Variant hospital admissions (CDC) Is susceptibility and severity of COVID-19 inheritabile (Nat Comm) Neonates of vaccinated mothers (JAMA) How is the monovalent XBB.1.5 vaccine effectiveness against symptomatic infection Sept 2023-Jan 2024 (MMWR) Second dose in the opposite arm improves antibody response (JCI) Virus specific immune repsonses following contralateral or ipsilateral immunication (eBioMedicine) CDC Quarantine guidelines (CDC) To rebound or to not rebound (MMWR) Know your COVID-19 tools (ESMED) How to pay for Paxlovid (PAXCESS) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (IDSociety) Steroids,dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) How COVID-19 affected your sleep (Frontiers in Public Health) Health and economic burden of COVID-19 after illness (BMC Medicine) Predicting recovery from fatigue and cognitive deficits after COVID-19 (eClinical Medicine) Contribute to our ASTMH fundraiser at PWB Letters read on TWiV 1086 Dr. Griffinâs COVID treatment summary (pdf) Timestamps by Jolene. Thanks!Intro music is by Ronald Jenkees
Send your questions for Dr. Griffin to [email protected]
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TWiV reviews measles outbreaks in England and Europe, 2 fatal Nipah virus cases in Bangladesh, yellow fever outbreak in Sudan, and discuss how the type of immunodeficiency influences the outcome of SARS-CoV-2 infection, and programming of alveolar macrophages by intestinal bacteria that influences severity of respiratory viral infection.
Hosts: Vincent Racaniello, Dickson Despommier, and Rich Condit
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Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Become a member of ASV (asv.org) Research assistant position in Rosenfeld Lab CBER/FDA (pdf) The New City by Dickson Despommier Viruses of Microbes 2024 Pig virus imperils food security in Borneo (Science) Measles outbreaks in UK and Europe (Nature) Fatal Nipah virus infections in Bangladesh (CIDRAP) Yellow fever outbreak in Sudan (Crisis24) COVID-19 influenced by type of immunodeficiency (Sci Transl Med) Intestinal microbiota programming of alveolar macrophages (Cell Host Microbe) Letters read on TWiV 1085 Timestamps by Jolene. Thanks! Weekly PicksDickson â JWST details of 19 spiral galactic centers
Listener Picks
Rich â Great White Shark Attack And Breach
Vincent â Black History Month and Lost Photographs of Black AmericaLouise â The Mystery Of The Village That Beat The Black Death
Pierre â Three things airlines donât want you to know
Brandon â Professor Dave explainsIntro music is by Ronald Jenkees
Send your virology questions and comments to [email protected]
-
In his weekly clinical update, Dr. Griffin discusses the how the pandemic influenced the healthcare job market before he reviews most recent statistics on the circulation of respiratory syncytial virus, influenza virus and SARS-CoV-2 virus, including all circulating variants in the US, discusses the safety of the prefusion RSV vaccine, if high or moderate dose of the quadrivalent influenza vaccine is better for protection against hospitalization, summarizes the new WHO COVID guidelines, revisits how to prevent pathogen transmission in healthcare setting, the under use of COVID oral antiviral and what occurs in persistently SARS-CoV-2 infected cells in culture after antiviral treatment, continues to dispel the myth of viral rebound, how to pay for paxlovid, when to use steroids and the benefits of convalescent plasma, how inflammatory markers change correlate with death when in ICU and if cognitive slowing is part of long COVID-19.
Subscribe (free): Apple Podcasts, Google Podcasts, RSS, emailBecome a patron of TWiV!
Links for this episode Do you want a job in healthcare? (JAMA) Respiratory disease surveillance (CDC) RSV surveillance (CDC) RSV national trend (CDC) Efficacy and safety of RSV vaccine after 2 seasons (CID) High vs moderate dose of quadrivalent influenza vaccine (CMI) Influenza/flu surveillance (CDC) Influenza/flu map (CDC) COVID-19 hospital admissions (CDC) COVID-19 national trend (CDC) COVID-19 wastewater testing (biobot) Variant tracker (CDC) Variant hospital admissions (CDC) WHO COVID guidance (WHO) Thoughts on COVID guidance (CIDRAP) Update on how to prevent pathogen transmission in healthcare settings (CDC) Underuse of antiviral drugs against COVID-19 (MMWR) Revisiting tissue culture cells persistently infected following antiviral therapy (bioRxiv) To rebound or to not rebound (MMWR) Know your COVID-19 tools (ESMED) How to pay for Paxlovid (PAXCESS) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (IDSociety) Steroids,dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Changes in inflammatory markers and death correlation when in ICU (Cytokine) Long COVID & cognitive slowing? (eClinicalMedicine) Contribute to our ASTMH fundraiser at PWB Letters read on TWiV 1084 Dr. Griffinâs COVID treatment summary (pdf) Timestamps by Jolene. Thanks!Intro music is by Ronald Jenkees
Send your questions for Dr. Griffin to [email protected]
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