Episoder
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In this episode, Gregory Huhn, MD, MPHTM, uses a case study to explore the reasons healthcare professionals and people living with HIV may want to further optimize ART in the setting of viral suppression.
To determine the best outcome for this case study, Dr Huhn discusses the reasons individuals may not be satisfied with daily oral ART and examines data to suggest that, for some individuals with virologic suppression, switching to long-acting ART may address internalized HIV stigma.
Finally, Dr Huhn takes a look at the optimal candidates for switching to a long-acting ART regimen and settings where proviral DNA genotyping may be considered prior to switching.
Presenter:
Gregory Huhn, MD, MPHTM
Interim Chief, Division of Infectious Diseases
Senior Director of HIV Services
Cook County HIV Integrated Programs
Interim Medical Director, The RMR CORE Center
Professor, Division of Infectious Diseases
Rush University Medical Center
Chicago, IllinoisTo access all of our new podcast episodes, subscribe to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.
See the full program here.
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In this episode, Maria Buti, MD, and her patient discuss opportunities to optimize care for people living with hepatitis B virus (HBV), including:
Barriers to HBV screening, including patient- and provider-specific barriers (eg, lack of education, failure to disclose or discuss risk factors, perceived low risk, stigma)Applying CDC recommendations for universal HBV screening in adults Strategies to improve HBV transitions of care (eg, improved education, simplify criteria for screening and monitoring, alternative testing sites)Importance of testing close contacts for HBV after initial diagnosis and promoting HBV vaccinationPresenter:
Maria Buti, MD
Professor of Medicine
Senior Consultant
Liver Unit
Hospital Universitario Valle Hebron
Barcelona, SpainContent based on an online CME program supported by an independent educational grant from Gilead Sciences, Inc.
Link to full program:
https://bit.ly/49TuZ8UGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.
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In this episode, Joseph J. Eron, Jr., MD, and Monica Gandhi, MD, MPH, discuss the key HIV studies from CROI 2024 that are influencing their clinical practice, including:
New data surrounding long-acting ART, including:The CARES study of LA CAB + RPV in a Sub-Saharan African population using a public health approachThe IMPAACT 2017 MOCHA study evaluating switching to LA CAB + RPV in adolescents living with HIVThe ACTG A5359 LATITUDE study of LA CAB + RPV in people with adherence challenges to oral ARTUpdated data from San Francisco’s Ward 86 Clinic using LA CAB + RPV in people without viral suppression at baselineCase series of LA CAB (± RPV) + LEN for select people living with HIV unable to take oral ART and unable to use LA CAB + RPV aloneData on comorbidities and coinfections, including:A REPRIEVE proteomic analysis to elucidate mechanistic pathways of statin effects on plaqueThe ACTG A5371 SLIM LIVER study of semaglutide for MASLD in people living with HIVThe impact of Doxy-PEP guideline implementation on STIs in men who have sex with men and transgender women in San FranciscoPotential novel treatment options on the horizon for people living with HIV, including:Phase II data on LEN + ISL dosed orally once weeklyEarly data on other oral weekly optionsData on bNAbs in combination or with other ART agentsPresenters:
Joseph J. Eron, Jr., MD
Professor of Medicine, School of Medicine
Herman and Louise Smith Distinguished Professor
Chief, Division of Infectious Diseases
Director, Clinical Core, UNC Center for AIDS Research
Adjunct Professor of Epidemiology
Gillings School of Global Public Health
University of North Carolina at Chapel Hill
Chapel Hill, North CarolinaMonica Gandhi, MD, MPH
Professor of Medicine
Division of HIV, Infectious Diseases, and Global Medicine
Medical Director, Ward 86 HIV Clinic
University of California, San Francisco
San Francisco, CaliforniaContent based on an online CME program supported by independent educational grants from Gilead Sciences; Merck & Co., Inc.; and ViiV Healthcare.
Link to full program:
https://bit.ly/4awdWJMGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts or Spotify.
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In this episode, Mark S. Sulkowski, MD, FIDSA, FAASLD; Tatyana Kushner, MD, MSCE; Paul Y. Kwo, MD; and patient advocate Jacki Chen, PhD, consider barriers and solutions for more expansive HBV treatment in the United States. Topics include:
Patient subgroups to consider for treatment outside guideline criteriaAdverse event and cost-effectiveness considerationsIntegration of patient perspectives in wider treatmentPresenters:
Mark S. Sulkowski, MD, FIDSA, FAASLD
Professor of Medicine
Director, Division of Infectious Diseases, Johns Hopkins Bayview Medical Center
Johns Hopkins University School of Medicine
Baltimore, MarylandTatyana Kushner, MD, MSCE
Associate Professor
Division of Liver Diseases
Icahn School of Medicine at Mount Sinai
New York, New YorkPaul Y. Kwo, MD
Professor of Medicine
Director of Hepatology
Stanford University School of Medicine
Palo Alto, CaliforniaJacki Chen, PhD
Patient AdvocateLink to full program:
https://bit.ly/3TuqFHILink to the slides:
https://bit.ly/4a60GM4Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.
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In this episode, Robert Wong, MD, MS, and a patient discuss opportunities to optimize care for people living with hepatitis B virus (HBV), including:
Opportunities to improve patient education, including education for expectant mothers with HBVPotential cultural considerations that may result in delayed HBV diagnosis and care Stigma reduction with universal HBV screening and vaccinationStrategies to improve patient education (eg, online resources, advocacy groups, use of layman’s terms and diagrams, repetition)Presenter:
Robert Wong, MD, MS
Clinical Associate Professor
Division of Gastroenterology and Hepatology
Stanford University School of Medicine
Palo Alto, CaliforniaContent based on an online CME program supported by an independent educational grant from Gilead Sciences, Inc.
Link to full program:
https://bit.ly/49TuZ8UGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.
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Listen to Roger Bedimo, MD, MS, FACP, discuss considerations for older people living with HIV, including:
Polypharmacy and deprescribingThe risk of cardiovascular events with various ART regimensApproaches for managing weight gainPresenter:
Roger Bedimo, MD, MS, FACP
Professor of Medicine
Interim Director, Office of Global Health
UT Southwestern Medical Center
Chief, Infectious Diseases Section
VA North Texas Health Care System
Dallas, TexasGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.
To download the slides:
https://bit.ly/49zrnZsTo view the full online program:
https://bit.ly/49x0W6D -
In this episode, Dr. Bedimo discusses best practices for individualized care in transgender women living with HIV, including:
Providing services in a gender-affirmative care modelProactive counseling on drug-drug interactions with gender-affirming hormone therapyStrategies to reduce adverse eventsPresenter:
Roger Bedimo, MD, MS, FACP
Professor of Medicine
Interim Director, Office of Global Health
UT Southwestern Medical Center
Chief, Infectious Diseases Section
VA North Texas Health Care System
Dallas, TexasGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.
To download the slides:
https://bit.ly/49zrnZsTo view the full online program:
https://bit.ly/49x0W6D -
In this episode, Renslow Sherer, MD, and Trinh P. Vu, PharmD, BCIDP, discuss how to optimize the use of COVID-19 antivirals and how to navigate drug-drug interactions between COVID-19 treatments and a patient’s home medications. Their discussion includes:
Current COVID-19 landscapeCOVID-19 testing and vaccination recommendationsTreatment guidelines and antiviral options for nonhospitalized adults with COVID-19Resources for assessing and managing COVID-19 antiviral-related drug-drug interactionsAnswers to learners’ most pressing questionsPresenters:
Renslow Sherer, MD
Professor of Medicine
Section of Infectious Diseases and Global Health
University of Chicago
Chicago, IllinoisTrinh P. Vu, PharmD, BCIDP
Clinical Pharmacy Specialist in Infectious Diseases
Department of Pharmacy
Emory University Hospital Midtown
Atlanta, GeorgiaSlideset: https://bit.ly/4c6kwbJ
Downloadable resource:
https://bit.ly/49rofP6Full program:
https://bit.ly/3P16TR8Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts or Spotify.
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In this episode, Nancy Reau, MD, discusses new data on hepatitis B virus presented at AASLD 2023, including:
Current therapiesStudies 108 and 110: Factors Linked With Lack of Virologic Suppression After 8 Yr of TAF or TDFKaiser Permanente Northern California: HCC or Death With TDF vs ETV for Chronic Hepatitis BEarly vs Late Postpartum Cessation of TDF Initiated for Prevention of Vertical HBV TransmissionInvestigational functional cure strategiesB-Together: Sequential Bepirovirsen and PegIFN Added to NA Therapy for Chronic HBV InfectionMARCH Part B: VIR-3434 ± VIR-2218 ± PegIFN Added to NA Therapy for Chronic HBV InfectionREEF-IT: JNJ-3989 + NA ± JNJ-6379 With PegIFN Add-on Consolidation in Patients With HBeAg-Positive CHBHBV003: VTP-300 + Nivolumab Added to NA Therapy for Chronic HBV InfectionCVP-NASVAC: Nasally Administered Therapeutic Vaccine for Chronic HBV InfectionPresenter:
Nancy Reau, MD
Professor of Medicine
Richard B. Capps Chair of Hepatology
Chief, Section of Hepatology
Associate Director, Solid Organ Transplantation
Rush University Medical Center
Chicago, IllinoisLink to full program:
https://bit.ly/47XJlU4 -
In this episode, LaRon E. Nelson, PhD, RN, FNP, FNAP, FNYAM, FAAN, discusses the role that healthcare professionals (HCPs) may be playing in their patients’ pre-exposure prophylaxis (PrEP) persistence and strategies to modify their approach to encourage persistence, from Clinical Care Options (CCO), including:
Racial disparities in the PrEP care continuumConsideration that PrEP persistence may be less about relationship to the drug than the environmentExamples of HCP implicit bias regarding PrEP responsibility based on racism and sexual prejudiceImpact of HCP implicit bias on PrEP persistenceImpact of racism on clinical cognitionThe demonstrated effects of stereotype threat and the potential healthcare implicationsWays to improve clinical conversations about PrEPProviding person-centered care to encourage PrEP persistence using the Client‑Centered Care Coordination (C4™) ModelFaculty
LaRon E. Nelson, PhD, RN, FNP, FNAP, FNYAM, FAAN
Independence Foundation Professor
School of Nursing
Yale University
New Haven, ConnecticutFollow along with the slides:
https://bit.ly/497cahKLink to full program:
https://bit.ly/3ZlICsLGet access to all of our new podcasts by subscribing to the CCO Infectious Disease podcast on Apple Podcasts, Google Podcasts, or Spotify.
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In this episode, Nancy Reau, MD, and her patient discuss opportunities to optimize care for people living with hepatitis B virus and hepatitis delta virus, including:
The importance of patient education along the care continuumEnsuring smooth transitions of care and communication between medical teamsScreening hepatitis delta in persons with chronic hepatitis BManaging hepatitis delta, including considerations for clinical trialsPromoting patient advocacyPresenter:
Nancy Reau, MD
Professor of Medicine
Chief, Section of Hepatology
Associate Director, Solid Organ Transplantation
Richard B. Capps Chair of Hepatology
Rush University Medical Center
Chicago, IllinoisContent based on an online CME program supported by an independent educational grant from Gilead Sciences, Inc.
Link to full program: bit.ly/3SrMuGO
Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.
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In this episode, David Saunders discusses the value of nonstigmatizing discussions between people using HIV pre-exposure prophylaxis (PrEP) and healthcare professionals, including:
Encouraging accountability to individualize adherence strategies and improve persistence to PrEPReducing stigma, discrimination, and prejudice in healthcare settings to foster PrEP persistenceFaculty:
David Saunders
PrEP User and AdvocateLink to full program:
https://bit.ly/3ZlICsLTo automatically get new episodes as soon as they launch, subscribe to the CCO Infectious Disease podcast.
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In this episode, Sarah M. Wood, MD, MS, discusses data and recommendations for long-acting pre-exposure prophylaxis (PrEP) as a strategy to support PrEP persistence and engagement for adolescents, including:
The PrEP care continuum for adolescentsSystem barriers to PrEP coverage and privacy concerns for adolescentsThe benefits and challenges of same-day PrEP initiation and real-world data to support itInterventions to support PrEP persistencePrEP options for different populations and the data to support the efficacy of long-acting cabotegravir (CAB) PrEP from HPTN 083 and HPTN 084Data and recommendations for a CAB PrEP oral lead-inData from HPTN 083 showing no interaction between feminizing hormone therapy and long-acting CAB PrEPProject LifeSkills: a culturally specific, empowerment-based, group-delivered behavioral HIV prevention intervention for young transgender womenFaculty
Sarah M. Wood, MD, MS
Assistant Professor of Pediatrics
Division of Adolescent Medicine
Perelman School of Medicine
University of Pennsylvania
Children’s Hospital of Philadelphia
Philadelphia, PennsylvaniaFollow along with the slides:
https://bit.ly/3Ha9KmtLink to full program:
https://bit.ly/3ZlICsLTo automatically get new episodes as soon as they launch, subscribe to the CCO Infectious Disease podcast show.
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In this episode, Angela Branche, MD, discusses RSV vaccines in older adults, including:
Current Advisory Committee on Immunization Practices recommendationsRisk factors associated with severe RSV disease, including RSV-related hospitalizationsApproach to stratifying risk factors (eg, age, comorbidities) in determining which adults may benefit from the RSV vaccine Ongoing research on RSV vaccines in younger adults (eg, aged 40s and 50s years) with chronic comorbidities Health disparities related to RSV vaccinesConsiderations for a risk-based approach, rather than age alone, to determine vaccine candidacyFaculty:
Angela Branche, MD
Associate Professor of Medicine
Division of Infectious Diseases
Department of Medicine
University of Rochester
Rochester, New YorkLink to full program:
https://bit.ly/3nb25xeLink to downloadable slides:
https://bit.ly/3TsXym5 -
In this episode, Douglas Dieterich, MD, leads a panel discussion with Camilla S. Graham, MD, MPH, and Robert Wong, MD, MS, to consider advantages and barriers to universal screening for chronic HBV infection and universal HDV screening in adults with HBV in the United States. Topics include:
Updated CDC recommendations for one-time universal screening for HBVAddressing patient-, provider-, and system-level barriers to universal HBV screeningBest practices for implementation of HDV screeningPresenters:
Douglas Dieterich, MD
Director, Institute for Liver MedicineProfessor of Medicine
Division of Liver Diseases
Mount Sinai School of Medicine
New York, New York
Camilla S. Graham, MD, MPH
Co-Director, Viral Hepatitis Clinic
Division of Infectious Diseases
Beth Israel Deaconess Medical Center
Harvard Medical School
Boston, MassachusettsRobert Wong, MD, MS
Clinical Associate Professor
Division of Gastroenterology and Hepatology
Stanford University School of Medicine
Palo Alto, CaliforniaLink to full program:
https://bit.ly/3TuqFHILink to the slides:
https://bit.ly/4atS42z -
In this episode, Tavell L. Kindall, PhD, DNP, ARNP, FNP-BC, AACRN, AAHIVS, FAANP, and Anne Teitelman, PhD, FNP-BC, FANNP, FAAN, discuss key PrEP considerations for advanced practice providers in primary care settings, including:
The importance of having PrEP navigators to help with logistics and be a point of contact for patients Where to find education and resources to familiarize yourself with PrEP and its prescribingSafety considerations and adverse events associated with PrEP optionsPrEP coverage and costHow to discontinue PrEP and the risk of resistance if someone acquires HIV while taking PrEPFaculty
Tavell L. Kindall, PhD, DNP, ARNP, FNP-BC, AACRN, AAHIVS, FAANP
Director, HIV Prevention and Treatment
St. Thomas Community Health Center
New Orleans, LouisianaAnne Teitelman, PhD, FNP-BC, FANNP, FAAN
Associate Professor Emeritus of Nursing and Global Women’s Health
Department of Family and Community Health
School of Nursing
University of Pennsylvania
Professor
Thomas Jefferson University
College of Nursing
Philadelphia, PennsylvaniaLink to full program:
https://bit.ly/3PZGYdR -
In this podcast episode, Mark Brennan-Ing, PhD, and Nina I. Martinez discuss mental health challenges in people living with HIV and much-needed strategies to overcome these challenges to optimize engagement in HIV care, including:
The increased rates of mental health disorders and substance use among people living with HIVHow mental health disorders contribute to challenges with adherence to HIV treatment and engagement in careHow social isolation and stigma can affect outcomes despite access to HIV care and ARTThe importance of mental health screenings as part of HIV careIntegrating mental health services into HIV care as a strategy to overcome mental health challenges being a barrier to carePresenter:
Mark Brennan-Ing, PhD
Director of Research and Evaluation
Brookdale Center for Healthy Aging
Hunter College
The City University of New York
New York, New YorkNina I. Martinez
Public Health ConsultantLink to full program:
https://bit.ly/3TqVnl1 -
In this podcast episode, Isolde Butler, MD, MPH, a healthcare professional caring for people living with HIV, and Marissa Gonzalez, an individual living with HIV, discuss strategies to improve healthcare professionals’ competencies in delivering optimal HIV care from the start to better support patients in overcoming barriers to sustained care engagement.
The topics they discuss include:
An introduction to the guidelines on ART initiation—start quickly and choose the therapy that is effective and tolerableThe patient experience, from initial diagnosis to treatment selection, noting that where people get diagnosed matters in determining the level of support they will receiveThe complete HIV care team: healthcare professionals, navigators, case managers, behavioral health providers, mental health providers, and so on. Smaller clinics may not be able to provide adequate support to meet all patient needsHow to navigate the first visit after an HIV diagnosis, including patient–provider treatment discussions on the available therapies that can help with stigmaHIV stigma education; navigating the miseducation and misinformationPresenters:
Isolde F. Butler, MD, MPH
Chief Medical Officer
Cresentcare
New Orleans, LouisianaMarissa Gonzalez
Chair
Community Advisory Board
The Well ProjectLink to full program:
https://bit.ly/3TqVnl1 -
In this podcast episode, Babafemi Taiwo, MBBS, and Vincent Crisostomo discuss the evolving treatment landscape for aging people living with HIV, encompassing the clinical and external resources necessary to support physical and psychosocial health. The topics discussed include:
• Mindful prescribing and understanding the impact an HIV diagnosis can have on one’s mental health, including social isolation
• How to address patients’ needs and establish a trusting relationship within the confines of a 15-minute clinic visit
• How research is helping healthcare professionals better understand this clinical situation and discover opportunities to equalize metrics
• The critical role of social workers and community organizations in patients’ overall care
• Accessing federal HIV disability resources
• Informed patient–provider discussion and counseling on medical decision-making regarding ART
• How healthcare professionals can move toward clinical practice that leaves no one behind
Presenter:
Babafemi Taiwo, MBBS
Gene Stollerman Professor of Medicine
Chief
Division of Infectious Diseases
Northwestern University Feinberg School of Medicine
Chicago, IllinoisVincent Crisostomo
Director
Aging Services
San Francisco AIDS Foundation
San Francisco, CaliforniaLink to full program:
https://bit.ly/3TqVnl1 -
In this episode, Kevin Astle, PharmD, BCPS, BCACP, AAHIVP, CDCES, discusses data and recommendations for providing HIV prevention options as a strategy to support PrEP persistence and engagement, including:
Postexposure prophylaxis (PEP) recommendations and the data for PEP-in-PocketOffering PrEP to everyone who receives PEPCurrently recommended PrEP options and the safety and adverse event considerations with each optionMonitoring recommendations for the different PrEP optionsThe importance of proactively addressing PrEP safety concerns that could lead to PrEP discontinuationFaculty
Kevin Astle, PharmD, BCPS, BCACP, AAHIVP, CDCES
Assistant Professor
Pharmacotherapeutics and Clinical Research
University of South Florida Taneja College of Medicine
Tampa, FloridaFollow along with the slides:
bit.ly/48cULUNLink to full program:
bit.ly/3ZlICsL - Se mer
