Episódios
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Episode 62! We talk briefly about two of the analyses that dropped with the ISICEM conference and then talk in depth about SESAR or "Inhaled Sedation in Acute Respiratory Distress Syndrome" by Jabudon et al in JAMA 2025. Then was answer a question on sleep in the ICU. Eddie did misspeak when he said one of the dexmedetomidine articles was in Lancet Respiratory medicine, rather, it was published in eClinical Medicine part of the Lancet network.
SESAR (JAMA): https://jamanetwork.com/journals/jama/fullarticle/2831857
SESAR (pubmed): https://pubmed.ncbi.nlm.nih.gov/40098564/
OVISS (pubmed): https://pubmed.ncbi.nlm.nih.gov/40098600/
Nocturnal dexmedetomidine (pubmed): https://pubmed.ncbi.nlm.nih.gov/29498534/
Nocturnal dexmedetomidine cardiac surgery (pubmed): https://pubmed.ncbi.nlm.nih.gov/36590787/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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Episode 61! We talk about HFNC including extubation to HFNC in "Early weaning from invasive mechanical ventilation via high-flow nasal oxygen versus conventional weaning in patients with hypoxemic respiratory failure" by Ayyawar et al published in Critical Care Science. Then we talk about weaning HFNC from the "How I do it" series from CHEST.
Auto-PEEP (NEJM): https://www.nejm.org/doi/full/10.1056/NEJM199307153290322
Extubate to HFNC (pubmed): https://pubmed.ncbi.nlm.nih.gov/39879434/
Extubate to HFNC (CCS): https://criticalcarescience.org/article/early-weaning-from-invasive-mechanical-ventilation-via-high-flow-nasal-oxygen-versus-conventional-weaning-in-patients-with-hypoxemic-respiratory-failure-a-prospective-randomized-controlled-study/
Weaning HFNC (pubmed): https://pubmed.ncbi.nlm.nih.gov/39929280/
Weaning HFNC (CHEST): https://journal.chestnet.org/article/S0012-3692(25)00155-2/abstractIf you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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Episode 60! We jump to SCCM where we talk about 2 late breakers - PROACTIVE or "Propranolol As an Anxiolytic to Reduce the Use of Sedatives for Critically Ill Adults Receiving Mechanical Ventilation" by Downar et al and "Acetylsalicylic Acid Treatment in Patients With Sepsis and Septic Shock" by Almeida et al both published in CCM in 2025.
PROACTIVE (pubmed): https://pubmed.ncbi.nlm.nih.gov/39982178/
PROACTIVE (CCM): https://pmc.ncbi.nlm.nih.gov/articles/PMC11801419/
ASA in sepsis (pubmed): https://pubmed.ncbi.nlm.nih.gov/39982179/
ASA in sepsis (CCM): https://journals.lww.com/ccmjournal/fulltext/2025/02000/acetylsalicylic_acid_treatment_in_patients_with.2.aspxIf you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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Episode 59! We finish our CCR down under coverage with TRAUMOX2 or "Early Restrictive vs Liberal Oxygen for Trauma Patients" published in JAMA by Arleth et al and then switch to SAHARA or "Liberal or Restrictive Transfusion Strategy in Aneurysmal Subarachnoid Hemorrhage" by English et al published in NEJM. We then frustrate Todd with questions from our mailbag, a good episode!
TRAUMOX2 (pubmed): https://pubmed.ncbi.nlm.nih.gov/39657224/
TRAUMOX2 (JAMA): https://jamanetwork.com/journals/jama/article-abstract/2827980
SAHARA (pubmed): https://pubmed.ncbi.nlm.nih.gov/39655786/
SAHARA (NEJM): https://www.nejm.org/doi/10.1056/NEJMoa2410962If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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Episode 58! We talk about non-invasive oxygen support and RENOVATE or "High-Flow Nasal Oxygen vs Noninvasive Ventilation in Patients With Acute Respiratory Failure" published in JAMA December 2024 and presented at the CCR Down Under Conference. We supplement this by first talking about FLORALI or "High-flow oxygen through nasal cannula in acute hypoxemic respiratory failure" published in NEJM May 2015
RENOVATE (pubmed): https://pubmed.ncbi.nlm.nih.gov/39657981/
RENOVATE (JAMA): https://jamanetwork.com/journals/jama/fullarticle/2828065
FLORALI (pubmed): https://pubmed.ncbi.nlm.nih.gov/25981908/
FLORALI (NEJM): https://www.nejm.org/doi/10.1056/NEJMoa1503326If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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Episode 57! We were excited to have on this episode Dr. Adam Wright who is a PhD in Bioinformatics to discuss SCREEN or "Electronic Sepsis Screening Among Patients Admitted to Hospital Wards: A Stepped-Wedge Cluster Randomized Trial" published by Arabi et al in JAMA 2024 and presented at the CCR Down Under Conference. A long episode but a lot of good discussion
SCREEN (pubmed): https://pubmed.ncbi.nlm.nih.gov/39658862/
SCREEN (JAMA): https://jamanetwork.com/journals/jama/article-abstract/2828069If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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Episode 56! In this episode we spend a few minutes talking about making decisions on ECMO initiation but spend most of the episode talking about ADAPT-Sepsis or "Biomarker-Guided Antibiotic Duration for Hospitalized Patients
With Suspected Sepsis" published by Dark et al in JAMA 2024 and presented at the CCR Down Under Conference.
ADAPT-Sepsis (pubmed): https://pubmed.ncbi.nlm.nih.gov/39652885/
ADAPT-Sepsis (JAMA): https://jamanetwork.com/journals/jama/article-abstract/2828036If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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Episode 55 and Happy New Year! In this episode we talk broad strokes about the CCR Down Under Conference and the trials that were presented, then Todd and Eddie go over a bunch of articles from the year 2024 that they didn't have time to go over or want to re-emphasize for whatever reason. Big show and we hope you enjoy!
TIGHT K: https://pubmed.ncbi.nlm.nih.gov/39215972/
PROPHY VAP: https://pubmed.ncbi.nlm.nih.gov/38262428/
REVISE: https://pubmed.ncbi.nlm.nih.gov/38875111/
Point (withdrawal of ECMO): https://pubmed.ncbi.nlm.nih.gov/39663030/
Counterpoint: https://pubmed.ncbi.nlm.nih.gov/39663031/
DanGer SHOCK: https://pubmed.ncbi.nlm.nih.gov/38587239/
Intubation in physiologic difficult airway guidelines: https://pubmed.ncbi.nlm.nih.gov/39162823/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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Episode 54! In this episode we talk about antibiotic duration in bacteremia (BALANCE) and also antibiotic duration in Pseudomonas Ventilator associated pneumonia (iDIAPASON).
BALANCE (NEJM): https://www.nejm.org/doi/full/10.1056/NEJMoa2404991
BALANCE (pubmed): https://pubmed.ncbi.nlm.nih.gov/39565030/
iDIAPASON (ICM): https://link.springer.com/article/10.1007/s00134-022-06690-5
iDIAPASON (pubmed): https://pubmed.ncbi.nlm.nih.gov/35552788/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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Episode 53! In this episode we talk about access in patients with out of hospital cardiac arrest. Both articles are similar so we talk in depth about IVIO and then bringing PARAMEDIC-3 to round out our discussion. A good acronym discussion too, don't miss it!
IVIO (NEJM): https://www.nejm.org/doi/10.1056/NEJMoa2407616
IVIO (pubmed): https://pubmed.ncbi.nlm.nih.gov/39480221/
PARAMEDIC-3 (NEJM): https://www.nejm.org/doi/full/10.1056/NEJMoa2407780
PARAMEDIC-3 (pubmed): https://pubmed.ncbi.nlm.nih.gov/39480216/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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Episode 52! In this episode we talk about fevers in acute neurologic injury and double that up with talking about low tidal volume ventilation in patients with neurologic injury
INTREPID (JAMA): https://jamanetwork.com/journals/jama/fullarticle/2824088
INTREPID (pubmed): https://pubmed.ncbi.nlm.nih.gov/39320879/
PROLABI (Blue): https://www.atsjournals.org/doi/full/10.1164/rccm.202402-0375OC
PROLABI (pubmed): https://pubmed.ncbi.nlm.nih.gov/39288368/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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We are (were) LIVE at ACNP Critical Care Bootcamp 2024! Thank you to the organizers of the conference for inviting us do a live show and thank you to everyone who came out to listen! We talk about the NONSEDA trial or "Nonsedation or Light Sedation in Critically Ill, Mechanically Ventilated Patients" by Olsen et al published in the New England Journal of Medicine February 2020
NONSEDA (pubmed): https://pubmed.ncbi.nlm.nih.gov/32068366/
NONSEDA (NEJM): https://www.nejm.org/doi/full/10.1056/NEJMoa1906759If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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Episode 50! In this episode we talk about SBT frequency and "Frequency of Screening and Spontaneous Breathing Trial Techniques" by Burns et al from JAMA 2024 that was released with the ESICM conference. In our second segment, instead of another trial we talk a little bit about the IV fluid shortage happening in the United States.
FAST (JAMA): https://jamanetwork.com/journals/jama/fullarticle/2824928
FAST (pubmed): https://pubmed.ncbi.nlm.nih.gov/39382222/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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We are LIVE at CHEST2024! Thank you to the organizers of the conference for inviting us do a live show and thank you to everyone who came out to listen! We talk about a few articles that were recently published in CHEST - "Prophylactic Minocycline for Delirium in Critically Ill Patients: A Randomized Controlled Trial" published by Dal-Pizzol et al and then "Comparative Effectiveness of Amiodarone and Lidocaine for the Treatment of In-Hospital Cardiac Arrest" by Wagner et al.
We then touch briefly on some articles being presented later at the conference which we might cover soon (stay tuned)!
Minocycline for Delirium (pubmed): https://pubmed.ncbi.nlm.nih.gov/38043911/
Minocycline for Delirium (CHEST): https://journal.chestnet.org/article/S0012-3692(23)05833-6/abstract
Amio vs Lido (pubmed): https://pubmed.ncbi.nlm.nih.gov/36332663/
Amio vs lido (CHEST): https://journal.chestnet.org/article/S0012-3692(22)04039-9/abstractIf you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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Episode 48! In this episode we talk about the long term effects of ICU visitation policies on families.
Long Term Outcomes of Visitation (pubmed): https://pubmed.ncbi.nlm.nih.gov/39172240/
Long Term Outcomes of Visitation (ICM): https://link.springer.com/article/10.1007/s00134-024-07577-3
Outcomes of Visitation (pubmed): https://pubmed.ncbi.nlm.nih.gov/31310297/
Outcomes of Visitation (JAMA): https://jamanetwork.com/journals/jama/fullarticle/2738289If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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Episode 47! In this episode we talk about a prospective observational study examining cognitive motor dissociation by Bodien et al published in the New England Journal of Medicine and then we pair that talking about the guidelines for death by neurologic criteria published in SCCM! An episode of somber but important topics!
Cognitive Motor Dissociation (pubmed): https://pubmed.ncbi.nlm.nih.gov/39141852/
Cognitive Motor Dissociation (NEJM): https://www.nejm.org/doi/10.1056/NEJMoa2400645
DBNC Guidelines (pubmed): https://pubmed.ncbi.nlm.nih.gov/37921516/
DBNC Guidelines (CCM): https://journals.lww.com/ccmjournal/fulltext/2024/03000/the_2023_american_academy_of_neurology,_american.3.aspxIf you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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Episode 46! In this episode we talk about thrombolytic windows in acute ischemic stroke from TIMELESS published by Albers et al published in the New England Journal of Medicine and then we talk about ANDROMEDA shock and serial lactates published by Hernandez et al!
TIMELESS (pubmed): https://pubmed.ncbi.nlm.nih.gov/38329148/
TIMELESS (NEJM): https://www.nejm.org/doi/10.1056/NEJMoa2310392
ANDROMEDA-Shock (pubmed):https://pubmed.ncbi.nlm.nih.gov/30772908/
ANDROMEDA-Shock (JAMA): https://jamanetwork.com/journals/jama/fullarticle/2724361If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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Episode 45! In this episode we talk about sepsis bundles and the 1-BED trial by Fruend et al and discuss the stress ulcer prophylaxis guidelines just published in SCCM!
1-BED (pubmed): https://pubmed.ncbi.nlm.nih.gov/38913098/
SUP Guidelines: https://www.sccm.org/Clinical-Resources/Guidelines/Guidelines/SCCM-ASHP-Guideline-Prevention-of-UGIBIf you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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We were honored to be joined by Joanna Stollings (and honestly we needed someone to keep us grounded) to talk about BLING3 or "Continuous vs Intermittent β-Lactam Antibiotic Infusions in Critically Ill Patients With Sepsis" published in JAMA by Dulhunty et al and also released with the CCR24 conference.
pubmed: https://pubmed.ncbi.nlm.nih.gov/38864155/
JAMA: https://jamanetwork.com/journals/jama/fullarticle/2819971If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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Episode 43! In this episode come close to finishing our dedicated discussion of the CCR24 trials talking about transfusion targets in TBI (HEMOTION) and dapagliflozin in critical illness (DEFENDER)!
HEMOTION: https://www.nejm.org/doi/full/10.1056/NEJMoa2404360
HEMOTION (pubmed): https://pubmed.ncbi.nlm.nih.gov/38869931/
DEFENDER: https://jamanetwork.com/journals/jama/fullarticle/2820242
DEFENDER (pubmed): https://pubmed.ncbi.nlm.nih.gov/38873723/
Bootcamp Details:
Vanderbilt University Medical Center is hosting its annual Critical Care ACNP/PA Bootcamp. This multi-specialty conference is designed for nurse practitioners and physician assistants working in critical care. The program, now in its thirteenth year, features a mix of lectures, roundtable discussions, expert Q&A sessions and networking opportunities aimed at both new and experienced providers. #CCBootcamp2024Dates: September 4-5, 2024 from 08:00 AM - 3:30 PM each day
Target Audience: This course is designed for nurse practitioners and physician assistants working in critical care.
Location: Loews Vanderbilt Hotel located at 2100 West End Ave, Nashville, TN
Registration: https://www.eventbrite.com/e/vumc-critical-care-acnppa-bootcamp-2024-tickets-830345073467?utm-campaign=social&utm-content=attendeeshare&utm-medium=discovery&utm-term=listing&utm-source=cp&aff=ebdsshcopyurl
More Info: https://www.vumc.org/advanced-practice-critical-careIf you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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