Episodes

  • Bob Harrington and Mitch Elkind discuss "food is medicine" initiatives and the challenges associated with conducting clinical trials.

    This podcast is intended for healthcare professionals only. To read a transcript or to comment, visit https://www.medscape.com/author/bob-harrington

    Health Care by Food Initiative https://healthcarexfood.org/

    2021 Dietary Guidance to Improve Cardiovascular Health: A Scientific Statement From the American Heart Association https://doi.org/10.1161/CIR.0000000000001031

    Rockefeller Foundation Food is Medicine https://www.rockefellerfoundation.org/initiative/food-is-medicine/

    Targeted Scientific Research Projects to Demonstrate Effectiveness of 'Food Is Medicine' in Health Care https://newsroom.heart.org/news/targeted-scientific-research-projects-to-demonstrate-effectiveness-of-food-is-medicine-in-health-care

    Food Is Medicine: A Presidential Advisory From the American Heart Association https://doi.org/10.1161/CIR.0000000000001182

    Medically Tailored Meal Delivery for Diabetes Patients With Food Insecurity: a Randomized Cross-over Trial https://doi.org/10.1007/s11606-018-4716-z

    'Food Is Medicine' Strategies for Nutrition Security and Cardiometabolic Health Equity: JACC State-of-the-Art Review https://doi.org/10.1016/j.jacc.2023.12.023

    Current Landscape of Produce Prescription Programs in the US https://doi.org/10.1016/j.jneb.2022.02.011

    Behavioral Nudges Are Used Widely to Steer Clinicians and Patients Alike https://doi.org/10.1056/CAT.23.0125

    A Primary Care Agenda for Brain Health: A Scientific Statement From the American Heart Association https://www.ahajournals.org/doi/10.1161/STR.0000000000000367#

    You may also like:

    Hear John Mandrola, MD's summary and perspective on the top cardiology news each week, on This Week in Cardiology https://www.medscape.com/twic

    Questions or feedback, please contact [email protected]

  • Bob Harrington interviews fellow cardiologist Mike McConnell about his new book Fight Heart Disease Like Cancer and the need to model heart disease prevention and treatment after cancer.

    This podcast is intended for healthcare professionals only.

    To read a transcript or to comment, visit https://www.medscape.com/author/bob-harrington

    Fight Heart Disease Like Cancer https://www.press.jhu.edu/books/title/12793/fight-heart-disease-cancer

    PREVENT: AHA's New Risk Calculator Incorporates CKM Health https://www.medscape.com/viewarticle/998679

    Artificial intelligence-enabled retinal vasculometry for prediction of circulatory mortality, myocardial infarction and stroke https://doi.org/10.1136/bjo-2022-321842

    You may also like:

    Hear John Mandrola, MD's summary and perspective on the top cardiology news each week, on This Week in Cardiology https://www.medscape.com/twic

    Questions or feedback, please contact [email protected]

  • Episodes manquant?

    Cliquez ici pour raffraichir la page manuellement.

  • Cardiology researchers Bob Harrington and Bobby Yeh discuss how to do better observational research and the controversial notion of making causal inferences from such data.

    This podcast is intended for healthcare professionals only.

    To read a transcript or to comment, visit https://www.medscape.com/author/bob-harrington

    Academic Cardiology and Social Media https://doi.org/10.1161/CIRCOUTCOMES.118.004736

    Bringing the Credibility Revolution to Observational Research and Cardiology https://doi.org/10.1161/CIRCULATIONAHA.123.064645

    Cardio Twitter: An Essential Tool for Staying Current https://www.medscape.com/viewarticle/897512

    Identification of Causal Effects Using Instrumental Variables https://doi.org/10.2307/2291629

    Explaining Charter School Effectiveness https://www.aeaweb.org/articles?id=10.1257/app.5.4.1

    Methods of Public Health Research - Strengthening Causal Inference from Observational Data https://doi.org/10.1056/NEJMp2113319

    Publish or Perish and the Incentive for Quantity over Quality Research Papers https://www.medscape.com/viewarticle/998417

    You may also like:

    Hear John Mandrola, MD's summary and perspective on the top cardiology news each week, on This Week in Cardiology https://www.medscape.com/twic

    Questions or feedback, please contact [email protected]

  • Bob Harrington, Erin Michos, and Brahmajee Nallamothu discuss how the publish or perish culture can lead to sloppy research and the need for alternative models to measure success in academic medicine.

    This podcast is intended for healthcare professionals only.

    To read a transcript or to comment, visit https://www.medscape.com/author/bob-harrington

    With Great Power Comes Great Responsibility

    Big Data Research From the National Inpatient Sample https://doi.org/10.1161/CIRCOUTCOMES.117.003846

    Adherence to Methodological Standards in Research Using the National Inpatient Sample

    https://doi.org/10.1001/jama.2017.17653

    Publish or Perish: Where are we heading?

    https://pubmed.ncbi.nlm.nih.gov/24778659

    The Kardashian Index of Cardiologists: Celebrities or Experts? https://doi.org/10.1016/j.jaccas.2019.11.068

    You may also like:

    Hear John Mandrola, MD's summary and perspective on the top cardiology news each week, on This Week in Cardiology

    https://www.medscape.com/twic

    Questions or feedback, please contact [email protected]

  • Bob Harrington and Mike Gibson discuss two of the hottest topics in cardiology and medicine for 2023: a proposed alternative to the maintenance of certification process, and artificial intelligence.

    This podcast is intended for healthcare professionals only.

    To read a transcript or to comment, visit

    https://www.medscape.com/author/bob-harrington

    Cardiovascular Organizations Pursue New, Independent Medical Board

    https://www.acc.org/About-ACC/Press-Releases/2023/09/21/15/02/Cardiovascular-Organizations-Pursue-New-Independent-Medical-Board

    The National Board of Physicians and Surgeons

    https://nbpas.org/

    Level of Scientific Evidence Underlying the Current American College of Cardiology/American Heart Association Clinical Practice Guidelines

    https://doi.org/10.1161/CIRCOUTCOMES.118.005293

    Validation of a Speech Analysis Application to Detect Worsening Heart Failure Events in Ambulatory Heart Failure Patients https://www.abstractsonline.com/pp8/?_ga=2.17782015.7532578.1693882428-1949139275.1663003561#!/10871/presentation/16568

    A systematic review shows no performance benefit of machine learning over logistic regression for clinical prediction models

    https://doi.org/10.1016/j.jclinepi.2019.02.004

    Recognizing a ruler instead of a cancer

    https://menloml.com/2020/01/11/recognizing-a-ruler-instead-of-a-cancer/

    The Geographic Bias in Medical AI Tools

    https://hai.stanford.edu/news/geographic-bias-medical-ai-tools

    You may also like:

    Medscape editor-in-chief Eric Topol, MD, and master storyteller and clinician Abraham Verghese, MD, on Medicine and the Machine

    https://www.medscape.com/features/public/machine

    Hear John Mandrola, MD's summary and perspective on the top cardiology news each week, on This Week in Cardiology

    https://www.medscape.com/twic

    Questions or feedback, please contact

    [email protected]

  • For this year's review, Bob Harrington and Mike Gibson revisit the major cardiology conferences -- from ACC in New Orleans to AHA in Philly.

    This podcast is intended for healthcare professionals only.

    To read a transcript or to comment, visit:

    https://www.medscape.com/author/bob-harrington

    ACC 2023 Top Trials

    - Bempedoic Acid Cuts CV Events in Statin-Intolerant Patients: CLEAR Outcomes https://www.medscape.com/viewarticle/989100

    - Bempedoic Acid and Cardiovascular Outcomes in Statin-Intolerant Patients

    - Phase 2b Randomized Trial of the Oral PCSK9 Inhibitor MK-0616 https://www.jacc.org/doi/10.1016/j.jacc.2023.02.018

    ACC/WCC 2023 Collection Page https://www.medscape.com/viewcollection/36966

    ESC 2023 Top Trials

    - Wegovy Scores HFpEF Benefits in People With Obesity https://www.medscape.com/viewarticle/995844

    - Semaglutide in Patients with Heart Failure with Preserved Ejection Fraction and Obesity https://www.nejm.org/doi/full/10.1056/NEJMoa2306963

    - Acoramidis Shows Encouraging Results in ATTR Cardiomyopathy https://www.medscape.com/viewarticle/995883

    ESC 2023 Collection Page https://www.medscape.com/viewcollection/36988

    AHA 2023 Top Trials

    - Semaglutide 'A New Pathway' to CVD Risk Reduction: SELECT https://www.medscape.com/viewarticle/998373

    - Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes https://www.nejm.org/doi/full/10.1056/NEJMoa2307563

    -
    Bariatric Surgery is Associated With Improved Coronary Microvascular Function and Cardiorespiratory Fitness in Patients With Ischemia and Non-Obstructive Coronary Arteries https://www.ahajournals.org/doi/10.1161/circ.148.suppl_1.18949

    - Angioplasty Finally Proven Beneficial in Stable Angina: ORBITA-2 https://www.medscape.com/s/viewarticle/998375

    - A Placebo-Controlled Trial of Percutaneous Coronary Intervention for Stable Angina https://www.nejm.org/doi/full/10.1056/NEJMoa2310610

    - Impressive Bleeding Profile With Factor XI Inhibitor in AF: AZALEA https://www.medscape.com/viewarticle/998418

    - Promising First Results With DNA Editing to Lower LDL https://www.medscape.com/s/viewarticle/998719

    - Single Injection Reduces Blood Pressure for 6 Months: KARDIA-1 https://www.medscape.com/viewarticle/998666

    AHA 2023 Collection Page https://www.medscape.com/viewcollection/37277

    Other Mentions

    - N-of-1 Trial of a Statin, Placebo, or No Treatment to Assess Side Effects https://www.nejm.org/doi/full/10.1056/NEJMc2031173

    - Rimonabant: From RIO to Ban https://doi.org/10.1155%2F2011%2F432607

    - Percutaneous coronary intervention in stable angina (ORBITA): a double-blind, randomised controlled trial https://doi.org/10.1016/S0140-6736(17)32714-9

    - Asundexian Phase 3 AF Study Halted for Lack of Efficacy https://www.medscape.com/viewarticle/998665

    - Challenges in the Design and Interpretation of Noninferiority Trials https://www.nejm.org/doi/full/10.1056/nejmra1510063

    - Milvexian for the Prevention of Venous Thromboembolism https://www.nejm.org/doi/full/10.1056/NEJMoa2113194

    You may also like:

    Medscape editor-in-chief Eric Topol, MD, and master storyteller and clinician Abraham Verghese, MD, on Medicine and the Machine

    https://www.medscape.com/features/public/machine

    Hear John Mandrola, MD's summary and perspective on the top cardiology news each week, on This Week in Cardiology

    https://www.medscape.com/twic

    Questions or feedback, please contact [email protected]

  • Bob Harrington and Manesh Patel discuss sudden cardiac death in athletes and the importance of the chain of survival.

    This podcast is intended for healthcare professionals only.

    To read a transcript or to comment, visit https://www.medscape.com/author/bob-harrington

    COVID and the Athlete's Heart

    https://www.medscape.com/viewarticle/945282

    Outcomes Registry for Cardiac Conditions in Athletes

    https://doi.org/10.1161/JAHA.122.029052

    2020 AHA/ACC Guideline for the Diagnosis and Treatment of Patients With Hypertrophic Cardiomyopathy

    https://doi.org/10.1161/CIR.0000000000000937

    Point-of-care screening for HFrEF using artificial intelligence during ECG-enabled stethoscope examination

    https://doi.org/10.1016/s2589-7500(21)00256-9

    International recommendations for electrocardiographic interpretation in athletes

    https://doi.org/10.1093/eurheartj/ehw631

    Elevation of Cardiac Troponins After Endurance Running Competitions

    https://doi.org/10.1161/CIRCULATIONAHA.118.034655

    Vigorous Exercise in Patients With Hypertrophic Cardiomyopathy

    https://doi.org/10.1001/jamacardio.2023.1042

    Eligibility and Disqualification Recommendations for Competitive Athletes With Cardiovascular Abnormalities: Preamble, Principles, and General Considerations

    https://doi.org/10.1161/CIR.0000000000000236

    RACE-CARS Trial

    https://racecarstrial.org/

    AHA CPR Resources

    https://cpr.heart.org/en/cpr-courses-and-kits/hands-only-cpr

    You may also like:

    Medscape editor-in-chief Eric Topol, MD, and master storyteller and clinician Abraham Verghese, MD, on Medicine and the Machine https://www.medscape.com/features/public/machine

    Hear John Mandrola, MD's summary and perspective on the top cardiology news each week, on This Week in Cardiology https://www.medscape.com/twic

    Questions or feedback, please contact [email protected]

  • Bob Harrington interviews Jag Singh about the COVID journey that led to his book, Future Care: Sensors, Artificial Intelligence, and the Reinvention of Medicine.

    This podcast is intended for healthcare professionals only. To read a transcript or to comment, visit: https://www.medscape.com/author/bob-harrington

    Future Care: Sensors, Artificial Intelligence, and the Reinvention of Medicine. https://www.jagsinghmd.com/book

    COVID-19 Hits Physician Couple: Dramatically Different Responses

    https://www.medscape.com/viewarticle/928530

    Smartwatch Electrocardiogram and Artificial Intelligence for Assessing Cardiac-Rhythm Safety of Drug Therapy in the COVID-19 Pandemic. The QT-logs study

    https://doi.org/10.1016/j.ijcard.2021.01.002

    The Care of the Patient

    https://doi.org/10.1001/jama.1927.02680380001001

    Advancements and future directions in the teamwork, targets, technology, and tight control-the 4T study: improving clinical outcomes in newly diagnosed pediatric type 1 diabetes

    https://doi.org/10.1097/mop.0000000000001140

    Social determinants of telemedicine utilization in ambulatory cardiovascular patients during the COVID-19 pandemic

    https://doi.org/10.1093/ehjdh/ztab039

    You may also like:

    Medscape editor-in-chief Eric Topol, MD, and master storyteller and clinician Abraham Verghese, MD, on Medicine and the Machine

    https://www.medscape.com/features/public/machine

    Hear John Mandrola, MD's summary and perspective on the top cardiology news each week, on This Week in Cardiology

    https://www.medscape.com/twic

    Questions or feedback, please contact: [email protected]

  • Robert Harrington, MD and Jenine John, a cardiologist and machine learning research fellow discuss what you need to know about AI and ML in healthcare and where to find some helpful resources.

    This podcast is intended for healthcare professionals only.

    To read a transcript or to comment, visit: https://www.medscape.com/author/bob-harrington

    'One Brave Idea' Recipient on Predicting Who Will Develop CAD

    https://www.medscape.com/viewarticle/874536

    Multinational Federated Learning Approach to Train ECG and Echocardiogram Models for Hypertrophic Cardiomyopathy Detection

    https://doi.org/10.1161/circulationaha.121.058696

    Application of Artificial Intelligence to the Electrocardiogram

    https://doi.org/10.1093/eurheartj/ehab649

    Using Machine Learning to Detect Problems in ECG Data Collection

    https://www.cinc.org/archives/2011/pdf/0437.pdf

    Age and Sex Estimation Using Artificial Intelligence From Standard 12-Lead ECGs

    https://doi.org/10.1161/CIRCEP.119.007284

    External Validation of a Widely Implemented Proprietary Sepsis Prediction Model in Hospitalized Patients

    http://jamanetwork.com/article.aspx?doi=10.1001/jamainternmed.2021.2626

    Sepsis Predictor Tool Falls Short in

    Emergency Setting

    https://www.medscape.com/viewarticle/982534

    Dissecting Racial Bias in an Algorithm Used to Manage the Health of Populations

    https://doi.org/10.1126/science.aax2342

    Geographic Distribution of US Cohorts Used to Train Deep Learning Algorithms https://jamanetwork.com/journals/jama/fullarticle/2770833

    Can Medical Algorithms Be Fair? Three Ethical Quandaries and One Dilemma

    https://doi.org/10.1136/bmjhci-2021-100445

    Healthcare Machine Learning: Getting Started

    https://medium.com/@jeninej/healthcare-machine-learning-getting-started-761a7dbb63a2

    What Clinicians Should Know About Healthcare AI, Part 1: Why Care About AI?

    https://medium.com/@jeninej/what-clinicians-should-know-about-healthcare-ai-part-1-why-care-about-ai-aba6a06f696d

    AI in Healthcare Specialization

    https://www.coursera.org/specializations/ai-healthcare

    You may also like:

    Medscape editor-in-chief Eric Topol, MD, and master storyteller and clinician Abraham Verghese, MD, on Medicine and the Machine: https://www.medscape.com/features/public/machine

    Hear John Mandrola, MD's, summary and perspective on the top cardiology news each week, on This Week in Cardiology: https://www.medscape.com/twic

    Questions or feedback, please contact: [email protected]

  • Bob Harrington talks to two former colleagues who made a mid- and senior-career switch to pharma and digital tech, respectively. How did they make this decision and what advice do they have for others?

    This podcast is intended for healthcare professionals only.

    To read a transcript or to comment

    https://www.medscape.com/author/bob-harrington

    Jeff Bezos - Regret Minimization https://www.youtube.com/watch?v=-qPii5ACVYw

    You may also like:

    Medscape editor-in-chief Eric Topol, MD, and master storyteller and clinician Abraham Verghese, MD, on Medicine and the Machine

    https://www.medscape.com/features/public/machine

    Hear John Mandrola, MD's summary and perspective on the top cardiology news each week, on This Week in Cardiology

    https://www.medscape.com/twic

    Questions or feedback, please contact

    [email protected]

  • Trials on heart failure, hypertension and lipid-lowering drugs, and the evolution of antithrombin and antiplatelet therapy are discussed in part 2 of cardiologists Bob Harrington and Mike Gibson's annual review.

    This podcast is intended for healthcare professionals only.

    To read a transcript or to comment, visit

    https://www.medscape.com/author/bob-harrington

    Lipid Lowering

    Safety, Tolerability and Efficacy of Up-Titration of Guideline-Directed Medical Therapies for Acute Heart Failure (STRONG-HF): A Multinational, Open-Label, Randomised, Trial

    https://doi.org/10.1016/S0140-6736(22)02076-1

    Why Combination Lipid-Lowering Therapy Should Be Considered Early in the Treatment of Elevated LDL-C for CV Risk Reduction

    https://www.acc.org/latest-in-cardiology/articles/2022/06/01/12/11/why-combination-lipid-lowering-therapy-should-be-considered

    Incidental Coronary Artery Calcium: Opportunistic Screening of Prior Non-gated Chest CTs to Improve Statin Rates (NOTIFY-1 Project)

    https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.122.062746

    Equivalent Impact of Elevated Lipoprotein(a) and Familial Hypercholesterolemia in Patients With Atherosclerotic Cardiovascular Disease

    https://doi.org/10.1016/j.jacc.2022.09.021

    Comparative Effects of Low-Dose Rosuvastatin, Placebo and Dietary Supplements on Lipids and Inflammatory Biomarkers

    https://doi.org/10.1016/j.jacc.2022.10.013

    Antihypertensive Drugs

    No Survival Advantage for Either Torsemide or Furosemide in HF: TRANSFORM-HF

    https://www.medscape.com/viewarticle/983611

    Chlorthalidone vs. Hydrochlorothiazide for Hypertension–Cardiovascular Events

    www.nejm.org/doi/full/10.1056/NEJMoa2212270

    Antiplatelets

    Duration of Antiplatelet Therapy After Complex Percutaneous Coronary Intervention in Patients at High Bleeding Risk: A MASTER DAPT Trial Sub-analysis

    https://doi.org/10.1093/eurheartj/ehac284

    PANTHER: Should Clopidogrel Become the 'New Aspirin' in CAD?

    https://www.medscape.com/viewarticle/980117

    P2Y12 Inhibitor Versus Aspirin Monotherapy for Secondary Prevention of Cardiovascular Events: Meta-analysis of Randomized Trials

    https://doi.org/10.1093/ehjopen/oeac019

    Ticagrelor Versus Clopidogrel in Patients With Acute Coronary Syndromes

    https://doi.org/10.1056/nejmoa0904327

    TCT-320 Pharmacokinetic and Pharmacodynamic Profile of PL-ASA, a Novel Phospholipid-Aspirin Complex Liquid Formulation, Compared to Enteric-Coated Aspirin at an 81-mg Dose – Results From a Prospective, Randomized, Crossover Study

    https://www.jacc.org/doi/10.1016/j.jacc.2021.09.1173

    Pharmacokinetic and Pharmacodynamic Profile of a Novel Phospholipid Aspirin Formulation

    https://europepmc.org/article/pmc/pmc8773391

    Antithrombins/Factor XI

    Rivaroxaban in Patients With a Recent Acute Coronary Syndrome

    https://www.nejm.org/doi/full/10.1056/nejmoa1112277

    Genetically Determined FXI (Factor XI) Levels and Risk of Stroke

    https://doi.org/10.1161/strokeaha.118.022792

    Factor XIa Inhibition With Asundexian After Acute Non-cardioembolic Ischaemic Stroke (PACIFIC-Stroke): an International, Randomised, Double-Blind, Placebo-Controlled, Phase 2b Trial

    https://doi.org/10.1016/s0140-6736(22)01588-4

    Safety of the Oral Factor Xia Inhibitor Asundexian Compared With Apixaban in Patients With Atrial Fibrillation (PACIFIC-AF): a Multicentre, Randomised, Double-Blind, Double-Dummy, Dose-Finding Phase 2 Study

    https://doi.org/10.1016/S0140-6736(22)00456-1

    A Multicenter, Phase 2, Randomized, Placebo-Controlled, Double-Blind, Parallel-Group, Dose-Finding Trial of the Oral Factor XIa Inhibitor Asundexian to Prevent Adverse Cardiovascular Outcomes After Acute Myocardial Infarction

    https://doi.org/10.1161/circulationaha.122.061612

    You may also like:

    Medscape editor-in-chief Eric Topol, MD, and master storyteller and clinician Abraham Verghese, MD, on Medicine and the Machine

    https://www.medscape.com/features/public/machine

    Hear John Mandrola, MD's summary and perspective on the top cardiology news each week, on This Week in Cardiology

    https://www.medscape.com/twic

    Questions or feedback? Please contact

    [email protected]

  • In part 1 of their annual review, cardiologists Bob Harrington and Mike Gibson discuss in-person meetings, wearables and AI, COVID lessons for medical research, and the growth of RCTs from China.

    This podcast is intended for healthcare professionals only. To read a transcript or to comment, visit

    https://www.medscape.com/author/bob-harrington

    COVID Therapies

    Therapeutic Anticoagulation With Heparin in Noncritically Ill Patients With Covid-19

    https://www.nejm.org/doi/full/10.1056/NEJMoa2105911

    Effect of Intermediate/High Versus Low Dose Heparin on the Thromboembolic and Hemorrhagic Risk of Unvaccinated COVID-19 Patients in the Emergency Department

    https://doi.org/10.1186/s12873-022-00668-8

    Two Old Meds and a DOAC a Bust Across Range of COVID Severity: The ACT Trials

    https://www.medscape.com/viewarticle/980049

    Effect of Ivermectin vs Placebo on Time to Sustained Recovery in Outpatients With Mild to Moderate COVID-19: A Randomized Clinical Trial

    http://jamanetwork.com/article.aspx?doi=10.1001/jama.2022.18590

    FDA Halts Use of Some COVID Monoclonal Antibodies Due to Omicron

    https://www.medscape.com/viewarticle/967210

    CT Surgeons Rise to Challenge, Lead Way in COVID Clinical Trials

    https://www.sts.org/publications/sts-news/ct-surgeons-rise-challenge-lead-way-covid-clinical-trials

    What Do We Know About Long COVID: A Cardiovascular Focus

    https://www.medscape.com/viewarticle/981435

    COVID-19 and the Heart: Is Cardiology Ready?

    https://www.medscape.com/viewarticle/969206

    The Stanford RECOVER Trial

    https://recovercovid.org/

    The Heroes Study

    https://heroesresearch.org/

    Artificial Intelligence

    Age and Sex Estimation Using Artificial Intelligence From Standard 12-Lead ECGs

    https://doi.org/10.1161/CIRCEP.119.007284

    The Heartline Study

    https://www.heartline.com/about

    Evolution of Single-Lead ECG for STEMI Detection Using a Deep Learning Approach

    https://doi.org/10.1016/j.ijcard.2021.11.039

    Recognizing a Ruler Instead of a Cancer

    https://menloml.com/2020/01/11/recognizing-a-ruler-instead-of-a-cancer/

    Machine Learning Did Not Beat Logistic Regression in Time Series Prediction for Severe Asthma Exacerbations

    https://doi.org/10.1038/s41598-022-24909-9

    A Systematic Review Shows No Performance Benefit of Machine Learning Over Logistic Regression for Clinical Prediction Models

    https://doi.org/10.1016/j.jclinepi.2019.02.004.

    Multinational Federated Learning Approach to Train ECG and Echocardiogram Models for Hypertrophic Cardiomyopathy Detection

    https://doi.org/10.1161/circulationaha.121.058696

    Detection of Hypertrophic Cardiomyopathy Using a Convolutional Neural Network-Enabled Electrocardiogram

    https://doi.org/10.1016/j.jacc.2019.12.030

    Here's Why We're Not Prepared for the Next Wave of Biotech Innovation (by Matthew Herper)

    https://www.statnews.com/2022/11/03/why-were-not-prepared-for-next-wave-of-biotech-innovation/

    RCTs from China

    Bivalirudin Plus a High-Dose Infusion Versus Heparin Monotherapy in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention: A Randomised Trial

    https://doi.org/10.1016/S0140-6736(22)01999-7

    Chinese Herbal Medicine May Offer Benefits in STEMI: CTS-AMI

    https://www.medscape.com/viewarticle/983619

    You may also like:

    Medscape editor-in-chief Eric Topol, MD, and master storyteller and clinician Abraham Verghese, MD, on Medicine and the Machine

    https://www.medscape.com/features/public/machine

    Hear John Mandrola, MD's summary and perspective on the top cardiology news each week on This Week in Cardiology

    https://www.medscape.com/twic

    Questions or feedback? Please contact

    [email protected]

  • Drs Bob Harrington and Betty Raman discuss the cardiovascular impact and long-term sequelae of COVID-19, the potential biology behind multisystem effects, and ongoing research.

    This podcast is intended for healthcare professionals only.

    To read a transcript or to comment, visit

    https://www.medscape.com/author/bob-harrington

    Medium-term Effects of SARS-CoV-2 Infection on Multiple Vital Organs, Exercise Capacity, Cognition, Quality of Life and Mental Health, Post-Hospital Discharge

    https://doi.org/10.1016/j.eclinm.2020.100683

    Prevalence and Impact of Myocardial Injury in Patients Hospitalized With COVID-19 Infection

    https://doi.org/10.1016%2Fj.jacc.2020.06.007

    Outcomes Among Confirmed Cases and a Matched Comparison Group in the Long-COVID in Scotland Study https://doi.org/10.1038/s41467-022-33415-5

    Long COVID: Post-Acute Sequelae of COVID-19 With a Cardiovascular Focus

    https://doi.org/10.1093/eurheartj/ehac031

    Cardiovascular Disease and COVID-19: A Consensus Paper From the ESC Working Group on Coronary Pathophysiology & Microcirculation, ESC Working Group on Thrombosis and the Association for Acute CardioVascular Care (ACVC), in Collaboration With the European Heart Rhythm Association (EHRA)

    https://doi.org/10.1093/cvr/cvab298

    Infection of Brain Pericytes Underlying Neuropathology of COVID-19 Patients

    https://doi.org/10.3390/ijms222111622

    COVID-19 and Fat Embolism: A Hypothesis to Explain the Severe Clinical Outcome in people With Obesity

    https://pubmed.ncbi.nlm.nih.gov/32514077

    Association Between Epstein-Barr-Virus Reactivation and Development of Long-COVID Fatigue

    https://doi.org/10.1111/all.15471

    Activation or Exhaustion of CD8+ T Cells in Patients With COVID-19

    https://doi.org/10.1038/s41423-021-00750-4

    Skeletal Muscle Alterations in Patients With Acute COVID-19 and Post-Acute Sequelae of COVID-19

    https://doi.org/10.1002/jcsm.12896

    Gut Microbiota Dynamics in a Prospective Cohort of Patients With Post-Acute COVID-19 Syndrome

    http://dx.doi.org/10.1136/gutjnl-2021-325989

    COVID-Vaccine Myocarditis: Rare, Mild, and Usually a Guy Thing

    https://www.medscape.com/viewarticle/966244

    Myocardial Injury Pattern at MRI in COVID-19 Vaccine–Associated Myocarditis

    https://doi.org/10.1148/radiol.212559

    Could Perturbation of Gut Microbiota Possibly Exacerbate the Severity of COVID-19 via Cytokine Storm?

    https://doi.org/10.3389/fimmu.2020.607734

    Myocarditis Associated With COVID-19 Vaccination

    https://doi.org/10.1161/CIRCIMAGING.121.013236

    COVID and the Athlete's Heart

    https://www.medscape.com/viewarticle/945282

    COVID-19 and the Heart: Is Cardiology Ready?

    https://www.medscape.com/viewarticle/969206

    Lung Abnormalities Depicted With Hyperpolarized Xenon MRI in Patients With Long COVID

    https://doi.org/10.1148/radiol.220069

    Long COVID Resource Center

    https://www.medscape.com/resource/long-covid

    You may also like:

    Medscape editor-in-chief Eric Topol, MD, and master storyteller and clinician Abraham Verghese, MD, on Medicine and the Machine.

    Hear John Mandrola, MD's, summary and perspective on the top cardiology news each week on This Week in Cardiology.

    Questions or feedback, please contact [email protected]

  • Do cardiologists from the AFFIRM generation treat AF less aggressively than the EAST-AFNET generation? Bob Harrington and Jonathan Piccini discuss this and upcoming trials on atrial fibrillation.

    This podcast is intended for healthcare professionals only.

    To read a transcript or to comment, visit:

    https://www.medscape.com/author/bob-harrington

    A Comparison of Rate Control and Rhythm Control in Patients with Atrial Fibrillation (AFFIRM)

    https://www.nejm.org/doi/full/10.1056/NEJMoa021328

    Early Rhythm-Control Therapy in Patients with Atrial Fibrillation (EAST-AFNET 4)

    https://www.nejm.org/doi/10.1056/NEJMoa2019422

    Early AF Rhythm-Control Advantage Climbs With Comorbidity Burden: EAST-AFNET4

    https://www.medscape.com/viewarticle/979627

    Early Dronedarone Versus Usual Care to Improve Outcomes in Persons With Newly Diagnosed Atrial Fibrillation (CHANGE-AFIB)

    https://clinicaltrials.gov/ct2/show/NCT05130268

    Generalizability of the EAST‐AFNET 4 Trial: Assessing Outcomes of Early Rhythm‐Control Therapy in Patients With Atrial Fibrillation

    https://doi.org/10.1161/JAHA.121.024214

    Early Rhythm Control Therapy for Atrial Fibrillation in Low-Risk Patients

    A Nationwide Propensity Score–Weighted Study

    https://doi.org/10.7326/M21-4798

    You may also like:

    Medscape editor-in-chief Eric Topol, MD, and master storyteller and clinician Abraham Verghese, MD, on Medicine and the Machine

    https://www.medscape.com/features/public/machine

    Hear John Mandrola, MD's summary and perspective on the top cardiology news each week, on This Week in Cardiology

    https://www.medscape.com/twic

    Questions or feedback, please contact

    [email protected]

  • Dr Bob Harrington talks with Drs Michelle Albert and Eldrin Lewis about the Association of Black Cardiologists' diversity scorecard for cardiovascular training programs.

    This podcast is intended for healthcare professionals only.

    To read a transcript or to comment, visit:

    https://www.medscape.com/author/bob-harrington

    The ABC Updates its CV DIBS Rankings | Association of Black Cardiologists

    https://abcardio.org/recent-news/the-abc-updates-its-cv-dibs-rankings/

    FDA Takes Important Steps to Increase Racial and Ethnic Diversity in Clinical Trials

    https://www.fda.gov/news-events/press-announcements/fda-takes-important-steps-increase-racial-and-ethnic-diversity-clinical-trials

    Gender Diversity in Cardiovascular Clinical Trial Research Begins at the Top

    https://www.jacc.org/doi/abs/10.1016/j.jacc.2022.01.001

    A Cluster-Randomized Trial of Blood-Pressure Reduction in Black Barbershops

    https://www.nejm.org/doi/full/10.1056/NEJMoa1717250

    At Black Barbershops, BP Reductions Still in Style at 1 Year

    https://www.medscape.com/viewarticle/906724

    Physician-Patient Racial Concordance and Disparities in Birthing Mortality for Newborns

    https://doi.org/10.1073/pnas.1913405117

    Racial and Ethnic Diversity at Medical Schools -- Why Aren't We There Yet?

    https://www.nejm.org/doi/full/10.1056/NEJMp2105578

    Medical School Enrollment More Diverse in 2021

    https://www.aamc.org/news-insights/press-releases/medical-school-enrollment-more-diverse-2021#r

    You may also like:

    Medscape editor-in-chief Eric Topol, MD, and master storyteller and clinician Abraham Verghese, MD, on Medicine and the Machine

    https://www.medscape.com/features/public/machine

    Hear John Mandrola, MD's summary and perspective on the top cardiology news each week, on This Week in Cardiology

    https://www.medscape.com/twic

    Questions or feedback, please contact:

    [email protected]

  • Robert A. Harrington interviews LaShyra Nolen, a medical student and the 2021 recipient of the American Medical Student Association's Racial Justice in Medicine Award.

    This podcast is intended for healthcare professionals only.

    To read a transcript or to comment, visit:

    https://www.medscape.com/author/bob-harrington

    How Medical Education Is Missing the Bull's-eye

    https://doi.org/10.1056/NEJMp1915891

    This Is What I Want To Tell My White Professors When They Ask, 'How Are You Today?'

    https://www.huffpost.com/entry/black-medical-student-wants-white-professors-to-know_n_5ed91238c5b6e0feefc26315

    Statue of Controversial Surgeon to Be Moved From Central Park

    https://www.medscape.com/viewarticle/891413

    A Rift Over Carl Linnaeus Shows We Shouldn't Idolise Scientists

    https://science.thewire.in/the-sciences/carl-linnaeus-entomological-society-of-america-great-man-theory-progress/

    Running Away from Drapetomania: Samuel A. Cartwright, Medicine, and Race in the Antebellum South

    https://muse.jhu.edu/article/699875

    What Led Chicago to Shutter Dozens of Majority-Black Schools? Racism

    https://www.theguardian.com/us-news/2018/dec/06/chicago-public-schools-closures-racism-ghosts-in-the-schoolyard-extract

    Call to Action: Structural Racism as a Fundamental Driver of Health Disparities: A Presidential Advisory From the American Heart Association

    https://doi.org/10.1161/CIR.0000000000000936

    You may also like:

    Medscape editor-in-chief Eric Topol, MD, and master storyteller and clinician Abraham Verghese, MD, on Medicine and the Machine

    https://www.medscape.com/features/public/machine

    Hear John Mandrola, MD's summary and perspective on the top cardiology news each week, on This Week in Cardiology

    https://www.medscape.com/twic

    Questions or feedback, please contact: [email protected]

  • Bob Harrington interviews fellow cardiologist Jacqueline Tamis-Holland, vice chair of the recent ACC/AHA revascularization guidelines, who takes us inside the process.

    This podcast is intended for healthcare professionals only.

    To read a transcript or to comment, visit

    https://www.medscape.com/author/bob-harrington

    2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization

    https://doi.org/10.1016/j.jacc.2021.09.006

    Evidence Based Medicine: What It Is and What It Isn't

    https://doi.org/10.1136/bmj.312.7023.71

    2016 ACC/AHA Guideline Focused Update on Duration of Dual Antiplatelet Therapy in Patients With Coronary Artery Disease:

    https://doi.org/10.1161/CIR.0000000000000404

    Ticagrelor With or Without Aspirin in High-Risk Patients After PCI

    https://doi.org/10.1056/NEJMoa1908419

    Surgical Groups Push Back Against New Revascularization Guidelines

    https://www.medscape.com/viewarticle/966153

    Outcomes in the ISCHEMIA Trial Based on Coronary Artery Disease and Ischemia Severity

    https://doi.org/10.1161/CIRCULATIONAHA.120.049755

    The Invisible Hand — Medical Care During the Pandemic

    https://www.nejm.org/doi/full/10.1056/NEJMp2006607

    You may also like:

    Medscape Editor-in-Chief Eric Topol, MD, and master storyteller and clinician Abraham Verghese, MD, on Medicine and the Machine

    https://www.medscape.com/features/public/machine

    Hear John Mandrola, MD's summary and perspective on the top cardiology news each week, on This Week in Cardiology

    https://www.medscape.com/twic

    Questions or feedback, please contact

    [email protected]

  • Robert Harrington, MD, interviews Ziyad Al-Aly, MD, about his recent paper in Nature Medicine focused on the long-term cardiovascular effects of COVID-19.

    This podcast is intended for healthcare professionals only.

    To read a transcript or to comment, visit

    https://www.medscape.com/author/bob-harrington

    Robert A. Harrington, MD, Arthur L. Bloomfield Professor; Chair, Department of Medicine, Stanford University; Chair, Department of Medicine, Stanford Medical Center, Stanford, California

    Ziyad Al-Aly, MD, Chief of Research and Development, VA St. Louis Health Care System, St. Louis, Missouri

    COVID-19 and Long-term Health

    Long-Term Cardiovascular Outcomes of COVID-19 https://doi.org/10.1038/s41591-022-01689-3

    High-Dimensional Characterization of Post-acute Sequelae of COVID-19

    https://doi.org/10.1038/s41586-021-03553-9

    Risks of Mental Health Outcomes in People With COVID-19: Cohort Study

    https://doi.org/10.1136/bmj-2021-068993

    Kidney Outcomes in Long COVID

    https://doi.org/10.1681/ASN.2021060734

    I'm 26. Coronavirus Sent Me to the Hospital.

    https://www.nytimes.com/2020/03/23/opinion/coronavirus-young-people.html

    You may also like:

    Medscape editor-in-chief Eric Topol, MD, and master storyteller and clinician Abraham Verghese, MD, on Medicine and the Machine

    https://www.medscape.com/features/public/machine

    Hear John Mandrola, MD's summary and perspective on the top cardiology news each week, on This Week in Cardiology

    https://www.medscape.com/twic

    Questions or feedback, please contact

    [email protected]

  • Trials on lowering salt consumption and treating hypertension in the community impressed Drs Harrington and Gibson in this discussion of the best public health research of 2021.

    This podcast is intended for healthcare professionals only.

    To read a transcript or to comment, visit:

    https://www.medscape.com/author/bob-harrington

    CV Public Health Trials

    Interim effects of salt substitution on urinary electrolytes and blood pressure in the China Salt Substitute and Stroke Study (SSaSS) https://doi.org/10.1016/j.ahj.2019.12.020

    A Cluster Randomized Trial of a Village Doctor-Led Intervention on Blood Pressure Control: China Rural Hypertension Control Project

    https://www.abstractsonline.com/pp8/?_ga=2.141042993.2042594723.1635046736-1021258137.1633710264#!/9349/presentation/18155

    A Remotely Delivered Hypertension and Lipid Program in 10,000 Patients Across a Diverse Health Care Network

    https://www.abstractsonline.com/pp8/?_ga=2.141042993.2042594723.1635046736-1021258137.1633710264#!/9349/presentation/18153

    COVID-19 Public Health Trials

    Impact of community masking on COVID-19: A cluster-randomized trial in Bangladesh

    https://www.poverty-action.org/publication/impact-community-masking-covid-19-cluster-randomized-trial-bangladesh

    Dexamethasone in Hospitalized Patients with Covid-19

    https://doi.org/10.1056/NEJMoa2021436

    Effect of Discontinuing vs Continuing Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers on Days Alive and Out of the Hospital in Patients Admitted With COVID-19

    https://jamanetwork.com/journals/jama/fullarticle/2775280

    The Recovery Trial Initiative

    https://www.recoverytrial.net/results

    You may also like:

    Medscape editor-in-chief Eric Topol, MD, and master storyteller and clinician Abraham Verghese, MD, on Medicine and the Machine

    https://www.medscape.com/features/public/machine

    Hear John Mandrola, MD's summary and perspective on the top cardiology news each week, on This Week in Cardiology

    https://www.medscape.com/twic

    Questions or feedback, please contact

    [email protected]

  • Drs Harrington and Gibson provide their annual roundup of what they consider the key cardiovascular trials of 2021. This podcast is intended for healthcare professionals only. To read a transcript or to comment, visit

    This podcast is intended for US healthcare professionals only.

    To read a full transcript of this episode or to comment please visit:

    https://www.medscape.com/viewarticle/963475

    https://www.medscape.com/author/bob-harrington

    Antiplatelet Therapy

    Comparative Effectiveness of Aspirin Dosing in Cardiovascular Disease

    https://doi.org/10.1056/NEJMoa2102137

    Dual Antiplatelet Therapy after PCI in Patients at High Bleeding Risk

    https://doi.org/10.1056/NEJMoa2108749

    Effect of 1-Month Dual Antiplatelet Therapy Followed by Clopidogrel vs 12-Month Dual Antiplatelet Therapy on Cardiovascular and Bleeding Events in Patients Receiving PCI

    https://doi.org/10.1001/jama.2019.8145

    Aspirin Versus Clopidogrel for Chronic Maintenance Monotherapy After Percutaneous Coronary Intervention (HOST-EXAM): An Investigator-Initiated, Prospective, Randomised, Open-Label, Multicentre Trial

    https://doi.org/10.1016/S0140-6736(21)01063-1

    SGLT2 Inhibitors and GLP-1 Agonists

    Empagliflozin in Heart Failure with a Preserved Ejection Fraction

    https://www.nejm.org/doi/full/10.1056/NEJMoa2107038

    Once-Weekly Semaglutide in Adults with Overweight or Obesity

    https://www.nejm.org/doi/full/10.1056/NEJMoa2032183

    Cardiac Surgery and PCI

    Left Atrial Appendage Occlusion during Cardiac Surgery to Prevent Stroke

    https://doi.org/10.1056/NEJMoa2101897

    Concomitant Tricuspid Repair in Patients with Degenerative Mitral Regurgitation

    https://doi.org/10.1056/NEJMoa2115961

    Fractional Flow Reserve–Guided PCI as Compared with Coronary Bypass Surgery

    https://doi.org/10.1056/NEJMoa2112299

    You may also like:

    Medscape editor-in-chief Eric Topol, MD, and master storyteller and clinician Abraham Verghese, MD, on Medicine and the Machine

    https://www.medscape.com/features/public/machine

    Hear John Mandrola, MD's summary and perspective on the top cardiology news each week, on This Week in Cardiology

    https://www.medscape.com/twic

    Questions or feedback? Please contact [email protected]