Episoder
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💬 In this note:
* 📘 GUIDEBOOK | Age-Fighting Drugs for Longevity
* 📚 The Law According to Lidia Poët
* ⚡️ Shephard
This week I’ve created a guidebook to educate about age-fighting drugs.
Age-fighting drugs like Resveratrol, NMN, Metformin and Rapamycin which show promising results which could redefine how we approach aging.
In the guidebook, I cover:
* What age-fighting drugs are
* Senolytics
* Resveratrol
* NAD+ Boosters
* NMN
* Metformin
* Rapamycin
* Calorie Restriction Mimetics
Check it out in my latest newsletter, or download the guide FOR FREE from my website.
Links:
The Law According to Lidia Poët
Shepherd: The author-curated book discovery tool,
Thank you for listening to Nina’s Notes #84. This post is public so feel free to share it.
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🍄 Ever wondered why you yawn during a psychedelic experience?
I cover several fascinating theories behind this phenomenon in my latest Nina’s Note.
From brain cooling to an emotional release, learn what might be the cause of the yawn.
💬 In this note:
* 🥱🌈 Why Do We Yawn On Psychedelics?
* 📚 The Atlas Complex
* ⚡️ What’s Going on at the Fly Ranch?
Links:
* View the art at the Fly Ranch on DesignBloom
* The Atlas Six by Olivie Blake
* The Atlas Paradox by Olivie Blake
* The Atlas Complex by Olivie Blake
* Unusual Side Effects of Clomipramine Associated with Yawning
* Physiology, role and neuropharmacology of yawning
Thank you for listening to Nina’s Notes. This post is public so feel free to share it.
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Mangler du episoder?
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🎙️ INTERVIEW | The Holistic Approach to Brain Health with Dr. Sabine Krofczik-Wilhelm
In this episode, my guest is Dr. Sabine Krofczik-Wilhelm, the Head of the Neurodegenerative Disorders Pillar for PPD, part of Thermo Fisher, where she is responsible for the strategic and operational delivery of clinical trials in dementia.
Sabine is passionate about brain health and longevity, and is actively working on de-stigmatizing dementia.
In our discussion, we explore a multifaceted approach to brain health, emphasizing its connection to overall well-being through physical, mental, social, and spiritual practices.
Sabine shares her personal journey with lifestyle interventions like fasting and the ketogenic diet, while also highlighting the cutting-edge research and therapies currently being explored for neurodegenerative disorders.
She advocates for building cognitive reserve through lifelong learning and highlights the benefits of sleep, diet, and fasting on mental acuity. The importance of social bonds and community engagement is underscored in her discussion about maintaining cognitive health.
Sabine addresses the challenges posed by an aging population and the stigma surrounding dementia, advocating for increased awareness, acceptance, and proactive measures to prevent neurodegenerative diseases.
Additionally, she is enthusiastic about advances in technology such as health-monitoring devices, like CGMs and the Oura Ring, and the use of digital therapeutics in psychiatry.
Key Takeaways:
* Brain health is a holistic concept that encompasses physical, mental, social, and spiritual well-being.
* Building cognitive reserve through lifelong learning is crucial for maintaining brain health.
* Quality sleep and a healthy diet, including fasting, can optimize cognitive function and brain health.
* Social connections and community involvement play a significant role in maintaining brain health. Raising awareness and support is crucial in destigmatizing dementia and improving the lives of those living with the disease.
* There is a need for literacy, acceptance, and inclusion in communities to provide better support for individuals with dementia.
* As the aging population increases, it is important to take action to prevent neurodegenerative disorders and find ways to integrate and include older adults in society.
* Healthy living, sustainable housing, and connecting with nature are important for brain health.
Listen now on Apple Podcasts.
Timestamps
* 00:00: Introduction and Background
* 01:56: Clinical Research in Neurodegenerative Diseases
* 04:16: Understanding Brain Health
* 06:14: Signs of Poor Brain Health
* 09:06: It's Never Too Late for Brain Health
* 11:46: Small Changes for Big Impact
* 14:03: Aging and Brain Health
* 21:07: The Importance of Sleep for Brain Health
* 24:19: Optimizing Brain Health through Diet
* 31:32: Social Connections and Brain Health
* 35:27: Destigmatizing Dementia: Raising Awareness and Support
* 42:35: Challenges of an Aging Population and Stigmatization of Dementia
* 45:54: Preventing Neurodegenerative Disorders and Integrating Older Adults in Society
* 52:08: The Finger Brain Health Institute: Advancing Research in Brain Health
* 56:36: Healthy Living, Sustainable Housing, and Nature's Impact on Brain Health
* 57:06: Monitoring Personal Health with Technology
* 59:42: Digital Therapeutics in Psychiatry: A Promising Field
Where to find Dr. Sabine Krofczik-Wilhelm:
* LinkedIn
Where to find Nina Patrick, PhD:
* Newsletter
* LinkedIn
* Website
Thank you for reading Nina’s Notes #82. This post is public so feel free to share it.
Edited by Wright Time Publishing
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🥱 Did you know that yawning could be your brain's natural air conditioning system?
Studies show that the act of yawning introduces cooler air into our bodies, which can help reduce our brain temperature.
Yawning is not just a signal that we are feeling tired—it's a sophisticated physiological response to help keep our brains cool!
💬 In this note:
* 🥱 Why Do We Yawn?
* 📚 Three Body Problem
* ⚡️ Digging a Tunnel Through Earth
Links:
Dr. Matthew Walker’s podcast episode, Yawning Explained.
The Three-Body Problem by Liu Cixin, translated by Ken Liu
The Dark Forest by Liu Cixin, translated by Joel Martinsen
Atlas Obscura’s maps of the antipode (the direct opposite) of the continents of Earth.
Thank you for listening to Nina’s Notes. This post is public so feel free to share it.
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Hi Friends,
It’s Nina’s Note #80!
In honor of this milestone, I have something new for you today, a debut interview for the Nina’s Notes Podcast.
On this inaugural episode, I am thrilled to welcome Michael Geer, a visionary determined to redefine our approach to aging.
🎙️ INTERVIEW | Your Rate of Aging with Michael Geer, Co-Founder of Humanity
Michael Geer is the Co-Founder of Humanity.
From a young age, Michael had an ambition to not just contribute to the world but to propel humanity forward. Initially this drive led him to study aerospace engineering at Georgia Tech University to chase that dream. While he didn’t end up in space (yet!). He is on a trajectory that promises to advance humanity nonetheless.
Geer’s professional career is marked with significant accomplishments in the consumer internet industry. His work started in Moscow, creating and building badoo.com, one of the world’s largest dating sites. He grew it to 70 million users from 0.
After Badoo, he moved to AnchorFree, the leading free VPN provider. Under his guidance it went from a single-app company to a leading global protector of the internet, boasting 700 million users and generating 100s of millions in yearly subscription revenue.
Now Michael has embarked on the mission of his life by co-founding Humanity with his close friend Peter Ward.
Humanity aims to combat a vast problem: aging. Their mission is to extend the healthspan of humanity and give back 1 billion years to the world by the end of this decade.
Backed by recent scientific breakthroughs in understanding aging, Humanity positions itself as a central distributor of anti-aging solutions. This isn't just about extending life but enhancing its quality. Humanity aims to be a bridge, delivering solutions to the public and creating a feedback loop with the scientific community.
In our conversation we discuss:
* What led Michael to start Humanity Health
* How Kristen Fortney, George Church and Robert Greene inspired Humanity
* What parameters Humanity uses to calculate biological age
* How they use routine blood test results to feed into their model for rate of aging
* The difference between chronological age and biological age
* How Humanity encourages their members to lower their biological age
* Using all the data to generate feedback loops
* Trends in Humanity’s data
* What Michael has changed in his personal routine after starting Humanity
Listen now on Apple Podcasts.
Try Humanity And Calculate Your Rate Of Aging
Use my promo code to get 50% off the Humanity Pro Subscription.
Promo code: NINAGIVES50PERCENTOFF
Humanity Pro allows users to upload any recent (last 6 months) blood result they've received and have it give them a more accurate Biological Age in the app.
Learn More About Humanity Health
* X
* LinkedIn
* Instagram
* Website
* YouTube
Where to find Michael Geer:
* X
* LinkedIn
Where to find Nina:
* Newsletter
* LinkedIn
* Website
Thank you for listening to Nina’s Notes. This post is public so feel free to share it.
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💬 In this note:
* 📘 Sleep for Longevity Guidebook
* 📚 Huberman Lab 6-Part Sleep Series
* ⚡️ The Tortured Poets Department
This week I’ve created a guidebook to up your sleep knowledge and help you optimize your sleep.
In the guidebook, I cover:
* The Science of Sleep
* Benefits of Deep Sleep
* Age-Related Changes in Sleep
* Sleep’s Metabolic Impact
* Sleep Environment Optimization
* Tech Tools for Sleep Enhancement
Links:
* Huberman Lab Podcast first 3 episodes of the 6-part series on Sleep with Dr. Matthew Wallker
* Part I: The Biology of Sleep & Your Unique Sleep Needs
* Part II: Protocols to Improve Your Sleep
* Part III: How to Structure Your Sleep, Use Naps & Time Caffeine
* Matthew Walker’s book, Why We Sleep: Unlocking the Power of Sleep and Dreams.
* Dr. Walker’s famous TEDTalk “Sleep is your Superpower.”
* Nina’s Notes #1
This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.notes.ninapatrick.xyz -
Essential oils are more than just a nice fragrance. They can be a tool for enhancing well-being.
These powerful plant extracts are known for reducing stress and inflammation and improving sleep.
In this week’s Nina’s Note I dive into how they are made, the chemistry and biology behind them and some common oils and their uses.
What was the most interesting thing I learned researching this article?
That essential oils need to be diluted in a carrier oil like coconut or jojoba oil - not used directly on the skin! In this form they are too strong and can cause skin irritation.
💬 In this note:
* 🪔 Nature’s Pharmacy: The Science Behind Essential Oils
* 📚 Foundation
* ⚡️ Zoo Snacks
📖 Want to read the latest Nina’s Notes?
Read the full article here
Links
* Foundation Series on AppleTV+
* The Top 5 munching moments from the animals at the San Antonio Zoo.
Thanks for listening to Nina’s Notes #78. If you like this newsletter, click the share button and send it to a friend.
This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.notes.ninapatrick.xyz -
🧠 Neuralink’s first human brain-computer interface implant trial marks a milestone for neurotech.
Patient 1 (P1), Noland Arbaugh, spoke about his experience at a Neuralink all-hands meeting two weeks ago with immense gratitude.
Already within the first month post-procedure, he can control a computer mouse with his mind and play several video games.
I watched the presentation at the all-hands meeting and was moved by Noland’s personal testimony.
Advancements in Neurotech will be revolutionary to overcoming paralysis and a range of neurological disorders.
Hear more about it in my latest Note.
💬 In this note:
* 🧠 Neuralink’s First Human Brain-Chip Implant Recipient Speaks About His Experience
* 📚 The Great Pottery Throwdown
* ⚡️ The Bird Diaper
Links
* P1’s visit to Neural link, watch the whole video on X here.
* The Great Pottery Throwdown
* The Bird Diaper
This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.notes.ninapatrick.xyz -
🐢 Are Millennials aging slower than Gen Z?
After a recent YouTube and TikTok spiral, I’ve seen a lot of theories and controversy around biological versus Chronological age 🕰️ between Gen X , Millennials and Gen Z.
In my latest Nina’s Note, I dive into the science, and pop culture, behind aging perceptions across generations
💬 In this note:
* 🐢 Are Millennials Aging Slower?
* 📚 Intellectual Property Strategy
* ⚡️ Symble
Links
* Jessica Ellis’ Tweet
* 2012 in the New England Journal of Medicine on the effects of skin aging.
* The New York Times article: “Why Does Gen Z Believe It’s ‘Aging Like Milk’?”
* YouTube video about how Gen Z thinks they look older than they should for their age.
* Jordan Howlett TikTok Video
* Taylor Donoghuee TikTok Video outraged that commenters thought she was in her early 30s, and she revealed she is just 23.
This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.notes.ninapatrick.xyz -
Ever wondered how art affects your brain and body?
In my latest Note, I explore this connection.
There is a whole field of study dedicated to it, called Neuroaesthetics.
I cover how the intersection of the arts and health can help with reducing pain, aiding in military mental health recovery, and how enriched environments can heal and improve lives.
I cover the breakthrough work from Marian Diamond, John Krakauer, Omar Ahmad, Promit Roy, the Kata Design Studio, Hunter Hoffman and David Patterson.
This article was inspired by the Book of the Week “Your Brain on Art: How the Arts Transform Us by Susan Magsamen & Ivy Ross”
This week’s Note is definitely a must-read for anyone passionate about the intersection of art, science, and health.
💬 In this note:
* 🧠🎨 Neuroaesthetics: The Beneficial Effects of Art on the Brain
* 📚 Your Brain on Art
* ⚡️ Amazing Deep Sea Creatures
Thanks for listening to Nina’s Notes #75. If you like Nina’s Notes, click the share button and send it to a friend.
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Athletes are pushing the boundaries of performance by microdosing and macrodosing psychedelics into their training.
From the LA Marathon to the Burning Man Ultramarathon, in my latest Note, I cover three athlete’s experiences and how substances like LSD and psilocybin impacted their endurance and emotional journeys.
💬 In this note:
* 🏃🏻♀️ Exploring the Edge: Psychedelics on the Race Track
* 📚 A Winter in New York
* ⚡️ What it’s Like to be a Librarian
Thanks for listening to Nina’s Notes #74. If you like this newsletter, click the share button and send it to a friend.
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In a recent review of randomized controlled trials, scientists found exercise to be a powerful tool for the treatment and prevention of peripheral neuropathy.
A big source of hope for these patients, for symptom management & prevention.
💬 In this note:
* 🏋🏽♀️ Prescribing Exercise for Peripheral Neuropathy
* 📚 Foundation
* ⚡️Language Loudness may be Climate Dependent
A couple weeks ago I was interviewed on the Mother podcast by host Karina Vazirova from FemTech Lab about Women’s Health and Psychedelics.
This is a significantly under researched area which could have a huge impact for women.
Check it out on Spotify, or wherever you get your podcasts.
This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.notes.ninapatrick.xyz -
Thermal therapy has been used for millennia for its health benefits.
I love the sauna.
But I hate, hate, hate an ice bath.
The science is there however, and I’ve written about it in my latest guidebook containing practical tips and protocols for incorporating hot and cold therapy into your routine.
(Even if I can’t convince myself to love an ice bath).
You can download the guidebook here:
And, you get an extra special bonus this week.
Two books of the week!
Plus…the moment you’ve all been waiting for to show the world your Excel skills.
💬 In this note:
* 📘 Guidebook: Thermal Therapy for Longevity
* 📚 The Mountain in the Sea
* ⚡️ The Excel World Championships
This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.notes.ninapatrick.xyz -
The next big advancement in AI will be driven by neuroscience.
Neuroplasticity, emotion and learning have huge potential for future advancements in AI.
Blending AI’s computational power with neuroscience will lead us to the next level in biology-inspired computation.
I’m learning about both neuroscience and AI, while I unpack some basics on how AI can leverage neuroscience principles in my latest Nina’s Note.
💬 In this note:
* 🤖 Why AI is Getting Stuck
* 📚 Incognito: the Secret Lives of the Brain
* ⚡️ An Octopus Traveling Across the Seafloor
Thanks for reading Nina’s Notes #71. If you like this newsletter, click the share button and send it to a friend.
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Men consistently live shorter lives than women.
This global phenomenon has a complex mix of factors.
It could be due to behavior, biology, genetics, healthcare habits and even social connections.
Understanding why women live longer could help unlock more secrets to longevity than just supplement boosters and biohacks.
💬 In this note:
* 🧓🏼 Why Do Men Live Shorter Lives Than Women?
* 📚 Happy Place
* ⚡️ The Unusual Collaboration Between Hidden Valley & Burt’s Bees
Thanks for reading Nina’s Notes #70. If you like this newsletter, click the share button and send it to a friend.
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The future of headache pain management may be in psychedelics.
While the spotlight has been on using psychedelics for mental health disorders like PTSD and Major Depressive Disorder—with legalization on the horizon in 2024 in the United States—the scope of psychedelic therapies is broadening.
Explore how new research with psychedelics could transform the way we combat migraine and cluster headaches, offering both preventative and instant effective pain relief in my latest Nina’s Notes.
💬 In this note:
* 🍄 Unlocking Relief: How Psychedelics are Reshaping Headache Treatments
* 📚 Starling House
* ⚡️ Enhanced Games
Thanks for reading Nina’s Notes #69. If you like this newsletter, click the share button and send it to a friend.
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The Western diet has ruined global health.
We now have reports forecasting that more than half of the world’s population will be overweight or obese by 2035.
That’s a very grim forecast.
The best medicine is a balanced diet with nutrient rich whole foods.
To help, I made a nutrition guide for longevity.
Download it at: https://ninapatrick.xyz/guides/
💬 In this note:
* 🥦 Nutrition for Longevity
* 📚 The Invisible Life of Addie LaRue
* ⚡️ Whale Conversations
Thanks for reading Nina’s Notes #68. If you like this newsletter, click the share button and send it to a friend.
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2024 is shaping up to be a groundbreaking year in the world of mental health and technology.
We may see the first psychedelic-assisted therapy to receive FDA approval in the USA. This will mark a historic shift in psychedelic research and a transformation of mental health treatment.
The future focus will shift to adoption and scalability.
Innovative approaches, like integrating VR into therapy, are emerging. This could allow at-home, VR-assisted sessions, broadening access and enhancing the therapy experience.
Check out how companies like Enosis Therapeutics and anuma are leveraging VR for psychedelic-assisted therapy experiences and as a digital therapeutic in my latest newsletter! Sign up to try anuma and join their waitlist.
Join my Longevity Wednesday Community by filling out this form.
Thanks for listening to Nina’s Notes #67. If you like this newsletter, click the share button and send it to a friend.
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Psychedelics have applications beyond mental health.
These "psychoplastogens," are gaining attention for their ability to promote neuroplasticity, and are stepping into the longevity arena, with potential applications in targeting issues like inflammation, oxidative stress, and blood-brain barrier disruption.
Terran Biosciences, a leading CNS-focused biotech company, is spearheading research into psychedelics for longevity with groundbreaking work including developing non-hallucinogenic versions of psychedelic therapeutics for wider clinical use.
Also in this week’s newsletter, I talk about Revolutionizing Mobility & Labor with Exosuits, highlighting exosuits from Verve Motion, ReWalk Robotics, HeroWear and cutting-edge research from Chung-Ang University offers a suit to enhance running speed
💬 In this note:
* 🍄 Psychedelics As Potential Longevity Therapeutics
* 📚 Mister Magic
* ⚡️ Wearable Robotic Exoskeletons
Download my Longevity Exercise Guide here: https://ninapatrick.xyz/guides/
Thanks for listening to Nina’s Notes #66. If you like Nina’s Notes, click the share button and send it to a friend.
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Menopause deserves more attention. Ovaries age twice as fast as other body tissues significantly impacting women’s health & longevity.
Women will spend 34% of their lifetime in poor health due to menopause.
The social, economic and personal empowerment from delayed menopause would have extraordinary implications for every woman’s life and the global economy.
The economic costs of infertility and menopause are staggering, with the menopause market exceeding $14B annually, it is definitely not a “niche” market.
I dive into some of the latest research to delay menopause in my latest Note. Check it out here.
💬 In this note:
* ⏸️ Can We Press Pause On Menopause?
* 📚 The Running Grave
* ⚡️ A Simple Smartphone Guidebook
Thanks for listening to Nina’s Notes #65. If you like Nina’s Notes, click the share button and send it to a friend.
This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.notes.ninapatrick.xyz - Se mer
