Episodes
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In this episode, Tristan J. Barber, MA, MD, FRCP, and Roger Bedimo, MD, MS, FACP, help you decide whether and how to modify ART in virologically suppressed individuals by critically appraising whether using newer agents may improve their treatment satisfaction.
Listen to their conversation about their own approaches to evaluating whether each person living with HIV is taking the best ART regimen for them, as well as ways to proactively assess challenges people may be facing with their HIV ART.
Presenters
Tristan J. Barber, MA, MD, FRCP
Consultant in HIV Medicine
Royal Free London NHS Foundation Trust
Honorary Associate Professor
Institute for Global Health
University College London
London, United KingdomRoger Bedimo, MD, MS, FACP
Professor of Medicine
Interim Director, Office of Global Health, UT Southwestern Medical Center
Chief, Infectious Diseases Section,
VA North Texas Health Care System
Dallas, TexasFollow along with the slides here.
https://bit.ly/44N2w2QSee the full program here.
https://bit.ly/450Ql2xGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.
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In this episode, Jonathan Appelbaum, MD, FACP, AAHIVS, discusses the updated CDC guidance on how to monitor for HIV in people receiving PrEP, including:
Rationale for why HIV monitoring differs for people receiving LA vs daily PrEPDescription of LEVI syndromeHow to transition a person from LA PrEP to HIV ART if they test positive for HIVPresenter:
Jonathan Appelbaum, MD, FACP, AAHIVS
Laurie L. Dozier, Jr., MD Education Director and Professor of Internal Medicine
Chair, Department of Clinical Sciences
Florida State University College of Medicine
Medical Director
Care Point Health and Wellness
Tallahassee, FloridaLink to the full program:
https://bit.ly/49x0W6DLink to the slideset:
https://bit.ly/4bzZothTo get access to all of our new podcast episodes, subscribe to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.
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In this episode, Jonathan Appelbaum, MD, FACP, AAHIVS, discusses the newest data supporting LA ART use in people with adherence challenges or viremia, including:
The LATITUDE study, an open-label phase III study of LA CAB + RPV in people with a suboptimal response or nonadherence to oral ARTUpdates to the Ward 86 cohort, which showed 81% of patients with viral suppression on LA CAB + RPV at Week 48The CARES study, an open-label, noninferiority phase IIIb study of LA CAB + RPV in people with baseline resistance mutationsPresenter:
Jonathan Appelbaum, MD, FACP, AAHIVS
Laurie L. Dozier, Jr., MD Education Director and Professor of Internal Medicine
Chair, Department of Clinical Sciences
Florida State University College of Medicine
Medical Director
Care Point Health and Wellness
Tallahassee, FloridaLink to the full program:
https://bit.ly/49x0W6DLink to the slideset:
https://bit.ly/4bzZothTo get access to all of our new podcast episodes, subscribe to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts or Spotify.
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In this episode, Angela Branche, MD, FIDSA, and Jewel Mullen, MD, MPH, MPA, FACP, address commonly asked questions about the RSV vaccine, including:
Considerations for vaccine eligibilityRecommendations for pregnant personsVaccine administration based on RSV seasonalityUse of the vaccine in persons receiving immunosuppressive medicationsSafety data (eg, risk of serious adverse events)Natural immunity of RSVVaccine cost and insurance coverageFaculty:
Angela Branche, MD, FIDSA
Associate Professor of Medicine
Division of Infectious Diseases
Department of Medicine
University of Rochester
Rochester, New YorkJewel Mullen, MD, MPH, MPA, FACP
Associate Dean for Health Equity
Associate Professor of Population Health and Internal Medicine
University of Texas at Austin Dell Medical School
Austin, TexasContent based on a CME program supported by an educational grant from GlaxoSmithKline.
Follow along with a downloadable slideset at:
https://bit.ly/44vCnFuLink to full program:
https://bit.ly/3WvSY9ZTo get access to all of our new podcasts, subscribe to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.
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In this episode, Jewel Mullen, MD, MPH, MPA, FACP, discusses strategies for implementing RSV vaccines into practice, with an emphasis on:
Understanding the reasoning for Advisory Committee on Immunization Practices RSV vaccine recommendations Factors that influence vaccine uptake and patient decision-makingConsiderations for patient and healthcare professional vaccine hesitancy Building vaccine confidence in both patients and healthcare professionalsUsing shared decision-making models (eg, SHARE approach)Faculty:
Jewel Mullen, MD, MPH, MPA, FACP
Associate Dean for Health Equity
Associate Professor of Population Health and Internal Medicine
University of Texas at Austin Dell Medical School
Austin, TexasContent based on a CME program supported by an educational grant from GlaxoSmithKline.
Follow along with a downloadable slideset at:
https://bit.ly/44vCnFuLink to full program:
https://bit.ly/3WvSY9ZTo get access to all of our new podcasts, subscribe to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.
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In this episode, Angela Branche, MD, FIDSA, explores the burden of RSV disease in older adults, including:
RSV seasonality and disease burdenSymptoms and complications of RSV infectionOlder age as a key risk factor for severe RSV disease and complications (eg, pneumonia, hospitalization)Comorbidities associated with increased risk of RSV hospitalizationRSV hospitalization rates among different racial and ethnic minority groups and socioeconomic statusesFaculty:
Angela Branche, MD, FIDSA
Associate Professor of Medicine
Division of Infectious Diseases
Department of Medicine
University of Rochester
Rochester, New YorkContent based on a CME program supported by an educational grant from GlaxoSmithKline.
Follow along with a downloadable slideset at:
https://bit.ly/44vCnFuLink to full program:
https://bit.ly/3WvSY9ZTo get access to all of our new podcasts, subscribe to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify
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Using common case scenarios, Robert H. Hopkins, Jr., MD, MACP, and Laura P. Hurley, MD, MPH, discuss strategies for optimizing shingles vaccine uptake, including:
The pathophysiology of shingles to better understand risk and burdenCDC guidelines and ACIP shingles vaccine recommendations, including considerations for those who are immunocompromised Strategies for optimizing shingles vaccine uptake no matter the clinical settingHow to address shingles vaccine‒related adverse events Addressing insurance-related concernsPresenters:
Robert H. Hopkins, Jr., MD, MACP
Professor of Internal Medicine and Pediatrics
Chief, Division of General Internal Medicine
University of Arkansas for Medical Sciences
School of Medicine
Little Rock, ArkansasLaura P. Hurley, MD, MPH
General Internist and Health Services Researcher
Associate Professor of Medicine
Department of General Internal Medicine
University of Colorado Anschutz Medical Campus
Aurora, ColoradoLink to downloadable slides:
https://bit.ly/4aWn6jhLink to full program:
https://bit.ly/4aWBiJ0Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.
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In this episode, Samantha Strong, PharmD, BCACP, AAHIVP, CDCES, and Nimish Patel, PharmD, PhD, AAHIVP, cover the most impactful clinical studies presented at CROI 2024, including:
New data on long-acting ART, including:The CARES study of LA CAB + RPV in a sub-Saharan African population using a public health approachThe IMPAACT 2017 MOCHA study evaluating switching to LA CAB + RPV in adolescents living with HIVThe ACTG A5359 LATITUDE study of LA CAB + RPV in people with adherence challenges to oral ARTUpdated data from San Francisco’s Ward 86 Clinic using LA CAB + RPV in people without viral suppression at baselineCase series of LA CAB (± RPV) + LEN for select people living with HIV unable to take oral ART and unable to use LA CAB + RPV aloneData on HIV and STI prevention, including:The impact of Doxy-PEP guideline implementation on STIs in men who have sex with men and transgender women in San FranciscoBIC/FTC/TAF for PEPOffering PrEP following PEPPresenters:
Samantha Strong, PharmD, BCACP, AAHIVP, CDCES
Clinical Director of Pharmacy
Nevada Health Centers
Las Vegas, NevadaNimish Patel, PharmD, PhD, AAHIVP
Professor of Clinical Pharmacy
Skaggs School of Pharmacy & Pharmaceutical Sciences
University of California, San Diego
La Jolla, CaliforniaTo access all of our new podcast episodes, subscribe to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.
See the full program here:
https://bit.ly/49x0W6D -
In this episode, learn how early and sustained HBV care can be enhanced by expanding the role of primary care providers in HBV management. Learn how to:
Engage key stakeholders in the provision of HBV careProvide HBV management resources to support PCPs who are doing screeningConsider specialty and primary care collaborations that empower PCPs with clear guidance on how to manage patients living with HBVPresenters:
Su Wang, MD, MPH, FACP
Medical Director
Center for Asian Health and Viral Hepatitis Programs
Cooperman Barnabas Medical Center
RWJBarnabas-Rutgers Medical Group
Associate Member
Health Care Policy and Aging Research
The Rutgers Institute for Health
Senior Advisor
Global Health, Hepatitis B Foundation
Florham Park, New JerseyRichard R. Andrews, MD, MPH
President, Houston Viral Hepatitis Task Force
Former Co-Chair, National Task Force on Hepatitis B
Board-Certified Family Medicine
Addiction Medicine Physician
Houston, TexasRuth Brogden, MPH
Patient AdvocateAmy S. Tang, MD
Former Co-Chair, National Task Force on Hepatitis B
Director of Immigrant Health
North East Medical Services
San Francisco, CaliforniaLink to full program:
https://bit.ly/3TuqFHILink to the slides:
https://bit.ly/44hXpHuGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.
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In this episode, Gregory Huhn, MD, MPHTM, uses a case study to explore the reasons healthcare professionals and people living with HIV may want to further optimize ART in the setting of viral suppression.
To determine the best outcome for this case study, Dr Huhn discusses the reasons individuals may not be satisfied with daily oral ART and examines data to suggest that, for some individuals with virologic suppression, switching to long-acting ART may address internalized HIV stigma.
Finally, Dr Huhn takes a look at the optimal candidates for switching to a long-acting ART regimen and settings where proviral DNA genotyping may be considered prior to switching.
Presenter:
Gregory Huhn, MD, MPHTM
Interim Chief, Division of Infectious Diseases
Senior Director of HIV Services
Cook County HIV Integrated Programs
Interim Medical Director, The RMR CORE Center
Professor, Division of Infectious Diseases
Rush University Medical Center
Chicago, IllinoisTo access all of our new podcast episodes, subscribe to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.
See the full program here.
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In this episode, Maria Buti, MD, and her patient discuss opportunities to optimize care for people living with hepatitis B virus (HBV), including:
Barriers to HBV screening, including patient- and provider-specific barriers (eg, lack of education, failure to disclose or discuss risk factors, perceived low risk, stigma)Applying CDC recommendations for universal HBV screening in adults Strategies to improve HBV transitions of care (eg, improved education, simplify criteria for screening and monitoring, alternative testing sites)Importance of testing close contacts for HBV after initial diagnosis and promoting HBV vaccinationPresenter:
Maria Buti, MD
Professor of Medicine
Senior Consultant
Liver Unit
Hospital Universitario Valle Hebron
Barcelona, SpainContent based on an online CME program supported by an independent educational grant from Gilead Sciences, Inc.
Link to full program:
https://bit.ly/49TuZ8UGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.
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In this episode, Joseph J. Eron, Jr., MD, and Monica Gandhi, MD, MPH, discuss the key HIV studies from CROI 2024 that are influencing their clinical practice, including:
New data surrounding long-acting ART, including:The CARES study of LA CAB + RPV in a Sub-Saharan African population using a public health approachThe IMPAACT 2017 MOCHA study evaluating switching to LA CAB + RPV in adolescents living with HIVThe ACTG A5359 LATITUDE study of LA CAB + RPV in people with adherence challenges to oral ARTUpdated data from San Francisco’s Ward 86 Clinic using LA CAB + RPV in people without viral suppression at baselineCase series of LA CAB (± RPV) + LEN for select people living with HIV unable to take oral ART and unable to use LA CAB + RPV aloneData on comorbidities and coinfections, including:A REPRIEVE proteomic analysis to elucidate mechanistic pathways of statin effects on plaqueThe ACTG A5371 SLIM LIVER study of semaglutide for MASLD in people living with HIVThe impact of Doxy-PEP guideline implementation on STIs in men who have sex with men and transgender women in San FranciscoPotential novel treatment options on the horizon for people living with HIV, including:Phase II data on LEN + ISL dosed orally once weeklyEarly data on other oral weekly optionsData on bNAbs in combination or with other ART agentsPresenters:
Joseph J. Eron, Jr., MD
Professor of Medicine, School of Medicine
Herman and Louise Smith Distinguished Professor
Chief, Division of Infectious Diseases
Director, Clinical Core, UNC Center for AIDS Research
Adjunct Professor of Epidemiology
Gillings School of Global Public Health
University of North Carolina at Chapel Hill
Chapel Hill, North CarolinaMonica Gandhi, MD, MPH
Professor of Medicine
Division of HIV, Infectious Diseases, and Global Medicine
Medical Director, Ward 86 HIV Clinic
University of California, San Francisco
San Francisco, CaliforniaContent based on an online CME program supported by independent educational grants from Gilead Sciences; Merck & Co., Inc.; and ViiV Healthcare.
Link to full program:
https://bit.ly/4awdWJMGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts or Spotify.
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In this episode, Mark S. Sulkowski, MD, FIDSA, FAASLD; Tatyana Kushner, MD, MSCE; Paul Y. Kwo, MD; and patient advocate Jacki Chen, PhD, consider barriers and solutions for more expansive HBV treatment in the United States. Topics include:
Patient subgroups to consider for treatment outside guideline criteriaAdverse event and cost-effectiveness considerationsIntegration of patient perspectives in wider treatmentPresenters:
Mark S. Sulkowski, MD, FIDSA, FAASLD
Professor of Medicine
Director, Division of Infectious Diseases, Johns Hopkins Bayview Medical Center
Johns Hopkins University School of Medicine
Baltimore, MarylandTatyana Kushner, MD, MSCE
Associate Professor
Division of Liver Diseases
Icahn School of Medicine at Mount Sinai
New York, New YorkPaul Y. Kwo, MD
Professor of Medicine
Director of Hepatology
Stanford University School of Medicine
Palo Alto, CaliforniaJacki Chen, PhD
Patient AdvocateLink to full program:
https://bit.ly/3TuqFHILink to the slides:
https://bit.ly/4a60GM4Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.
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In this episode, Robert Wong, MD, MS, and a patient discuss opportunities to optimize care for people living with hepatitis B virus (HBV), including:
Opportunities to improve patient education, including education for expectant mothers with HBVPotential cultural considerations that may result in delayed HBV diagnosis and care Stigma reduction with universal HBV screening and vaccinationStrategies to improve patient education (eg, online resources, advocacy groups, use of layman’s terms and diagrams, repetition)Presenter:
Robert Wong, MD, MS
Clinical Associate Professor
Division of Gastroenterology and Hepatology
Stanford University School of Medicine
Palo Alto, CaliforniaContent based on an online CME program supported by an independent educational grant from Gilead Sciences, Inc.
Link to full program:
https://bit.ly/49TuZ8UGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.
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Listen to Roger Bedimo, MD, MS, FACP, discuss considerations for older people living with HIV, including:
Polypharmacy and deprescribingThe risk of cardiovascular events with various ART regimensApproaches for managing weight gainPresenter:
Roger Bedimo, MD, MS, FACP
Professor of Medicine
Interim Director, Office of Global Health
UT Southwestern Medical Center
Chief, Infectious Diseases Section
VA North Texas Health Care System
Dallas, TexasGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.
To download the slides:
https://bit.ly/49zrnZsTo view the full online program:
https://bit.ly/49x0W6D -
In this episode, Dr. Bedimo discusses best practices for individualized care in transgender women living with HIV, including:
Providing services in a gender-affirmative care modelProactive counseling on drug-drug interactions with gender-affirming hormone therapyStrategies to reduce adverse eventsPresenter:
Roger Bedimo, MD, MS, FACP
Professor of Medicine
Interim Director, Office of Global Health
UT Southwestern Medical Center
Chief, Infectious Diseases Section
VA North Texas Health Care System
Dallas, TexasGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.
To download the slides:
https://bit.ly/49zrnZsTo view the full online program:
https://bit.ly/49x0W6D -
In this episode, Renslow Sherer, MD, and Trinh P. Vu, PharmD, BCIDP, discuss how to optimize the use of COVID-19 antivirals and how to navigate drug-drug interactions between COVID-19 treatments and a patient’s home medications. Their discussion includes:
Current COVID-19 landscapeCOVID-19 testing and vaccination recommendationsTreatment guidelines and antiviral options for nonhospitalized adults with COVID-19Resources for assessing and managing COVID-19 antiviral-related drug-drug interactionsAnswers to learners’ most pressing questionsPresenters:
Renslow Sherer, MD
Professor of Medicine
Section of Infectious Diseases and Global Health
University of Chicago
Chicago, IllinoisTrinh P. Vu, PharmD, BCIDP
Clinical Pharmacy Specialist in Infectious Diseases
Department of Pharmacy
Emory University Hospital Midtown
Atlanta, GeorgiaSlideset: https://bit.ly/4c6kwbJ
Downloadable resource:
https://bit.ly/49rofP6Full program:
https://bit.ly/3P16TR8Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts or Spotify.
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In this episode, Nancy Reau, MD, discusses new data on hepatitis B virus presented at AASLD 2023, including:
Current therapiesStudies 108 and 110: Factors Linked With Lack of Virologic Suppression After 8 Yr of TAF or TDFKaiser Permanente Northern California: HCC or Death With TDF vs ETV for Chronic Hepatitis BEarly vs Late Postpartum Cessation of TDF Initiated for Prevention of Vertical HBV TransmissionInvestigational functional cure strategiesB-Together: Sequential Bepirovirsen and PegIFN Added to NA Therapy for Chronic HBV InfectionMARCH Part B: VIR-3434 ± VIR-2218 ± PegIFN Added to NA Therapy for Chronic HBV InfectionREEF-IT: JNJ-3989 + NA ± JNJ-6379 With PegIFN Add-on Consolidation in Patients With HBeAg-Positive CHBHBV003: VTP-300 + Nivolumab Added to NA Therapy for Chronic HBV InfectionCVP-NASVAC: Nasally Administered Therapeutic Vaccine for Chronic HBV InfectionPresenter:
Nancy Reau, MD
Professor of Medicine
Richard B. Capps Chair of Hepatology
Chief, Section of Hepatology
Associate Director, Solid Organ Transplantation
Rush University Medical Center
Chicago, IllinoisLink to full program:
https://bit.ly/47XJlU4 -
In this episode, LaRon E. Nelson, PhD, RN, FNP, FNAP, FNYAM, FAAN, discusses the role that healthcare professionals (HCPs) may be playing in their patients’ pre-exposure prophylaxis (PrEP) persistence and strategies to modify their approach to encourage persistence, from Clinical Care Options (CCO), including:
Racial disparities in the PrEP care continuumConsideration that PrEP persistence may be less about relationship to the drug than the environmentExamples of HCP implicit bias regarding PrEP responsibility based on racism and sexual prejudiceImpact of HCP implicit bias on PrEP persistenceImpact of racism on clinical cognitionThe demonstrated effects of stereotype threat and the potential healthcare implicationsWays to improve clinical conversations about PrEPProviding person-centered care to encourage PrEP persistence using the Client‑Centered Care Coordination (C4™) ModelFaculty
LaRon E. Nelson, PhD, RN, FNP, FNAP, FNYAM, FAAN
Independence Foundation Professor
School of Nursing
Yale University
New Haven, ConnecticutFollow along with the slides:
https://bit.ly/497cahKLink to full program:
https://bit.ly/3ZlICsLGet access to all of our new podcasts by subscribing to the CCO Infectious Disease podcast on Apple Podcasts, Google Podcasts, or Spotify.
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In this episode, Nancy Reau, MD, and her patient discuss opportunities to optimize care for people living with hepatitis B virus and hepatitis delta virus, including:
The importance of patient education along the care continuumEnsuring smooth transitions of care and communication between medical teamsScreening hepatitis delta in persons with chronic hepatitis BManaging hepatitis delta, including considerations for clinical trialsPromoting patient advocacyPresenter:
Nancy Reau, MD
Professor of Medicine
Chief, Section of Hepatology
Associate Director, Solid Organ Transplantation
Richard B. Capps Chair of Hepatology
Rush University Medical Center
Chicago, IllinoisContent based on an online CME program supported by an independent educational grant from Gilead Sciences, Inc.
Link to full program: bit.ly/3SrMuGO
Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.
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