Episodes
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We are LIVE at CHEST2024! Thank you to the organizers of the conference for inviting us do a live show and thank you to everyone who came out to listen! We talk about a few articles that were recently published in CHEST - "Prophylactic Minocycline for Delirium in Critically Ill Patients: A Randomized Controlled Trial" published by Dal-Pizzol et al and then "Comparative Effectiveness of Amiodarone and Lidocaine for the Treatment of In-Hospital Cardiac Arrest" by Wagner et al.
We then touch briefly on some articles being presented later at the conference which we might cover soon (stay tuned)!
Minocycline for Delirium (pubmed): https://pubmed.ncbi.nlm.nih.gov/38043911/
Minocycline for Delirium (CHEST): https://journal.chestnet.org/article/S0012-3692(23)05833-6/abstract
Amio vs Lido (pubmed): https://pubmed.ncbi.nlm.nih.gov/36332663/
Amio vs lido (CHEST): https://journal.chestnet.org/article/S0012-3692(22)04039-9/abstractIf you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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Episode 48! In this episode we talk about the long term effects of ICU visitation policies on families.
Long Term Outcomes of Visitation (pubmed): https://pubmed.ncbi.nlm.nih.gov/39172240/
Long Term Outcomes of Visitation (ICM): https://link.springer.com/article/10.1007/s00134-024-07577-3
Outcomes of Visitation (pubmed): https://pubmed.ncbi.nlm.nih.gov/31310297/
Outcomes of Visitation (JAMA): https://jamanetwork.com/journals/jama/fullarticle/2738289If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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Episode 47! In this episode we talk about a prospective observational study examining cognitive motor dissociation by Bodien et al published in the New England Journal of Medicine and then we pair that talking about the guidelines for death by neurologic criteria published in SCCM! An episode of somber but important topics!
Cognitive Motor Dissociation (pubmed): https://pubmed.ncbi.nlm.nih.gov/39141852/
Cognitive Motor Dissociation (NEJM): https://www.nejm.org/doi/10.1056/NEJMoa2400645
DBNC Guidelines (pubmed): https://pubmed.ncbi.nlm.nih.gov/37921516/
DBNC Guidelines (CCM): https://journals.lww.com/ccmjournal/fulltext/2024/03000/the_2023_american_academy_of_neurology,_american.3.aspxIf you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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Episode 46! In this episode we talk about thrombolytic windows in acute ischemic stroke from TIMELESS published by Albers et al published in the New England Journal of Medicine and then we talk about ANDROMEDA shock and serial lactates published by Hernandez et al!
TIMELESS (pubmed): https://pubmed.ncbi.nlm.nih.gov/38329148/
TIMELESS (NEJM): https://www.nejm.org/doi/10.1056/NEJMoa2310392
ANDROMEDA-Shock (pubmed):https://pubmed.ncbi.nlm.nih.gov/30772908/
ANDROMEDA-Shock (JAMA): https://jamanetwork.com/journals/jama/fullarticle/2724361If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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Episode 45! In this episode we talk about sepsis bundles and the 1-BED trial by Fruend et al and discuss the stress ulcer prophylaxis guidelines just published in SCCM!
1-BED (pubmed): https://pubmed.ncbi.nlm.nih.gov/38913098/
SUP Guidelines: https://www.sccm.org/Clinical-Resources/Guidelines/Guidelines/SCCM-ASHP-Guideline-Prevention-of-UGIBIf you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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We were honored to be joined by Joanna Stollings (and honestly we needed someone to keep us grounded) to talk about BLING3 or "Continuous vs Intermittent β-Lactam Antibiotic Infusions in Critically Ill Patients With Sepsis" published in JAMA by Dulhunty et al and also released with the CCR24 conference.
pubmed: https://pubmed.ncbi.nlm.nih.gov/38864155/
JAMA: https://jamanetwork.com/journals/jama/fullarticle/2819971If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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Episode 43! In this episode come close to finishing our dedicated discussion of the CCR24 trials talking about transfusion targets in TBI (HEMOTION) and dapagliflozin in critical illness (DEFENDER)!
HEMOTION: https://www.nejm.org/doi/full/10.1056/NEJMoa2404360
HEMOTION (pubmed): https://pubmed.ncbi.nlm.nih.gov/38869931/
DEFENDER: https://jamanetwork.com/journals/jama/fullarticle/2820242
DEFENDER (pubmed): https://pubmed.ncbi.nlm.nih.gov/38873723/
Bootcamp Details:
Vanderbilt University Medical Center is hosting its annual Critical Care ACNP/PA Bootcamp. This multi-specialty conference is designed for nurse practitioners and physician assistants working in critical care. The program, now in its thirteenth year, features a mix of lectures, roundtable discussions, expert Q&A sessions and networking opportunities aimed at both new and experienced providers. #CCBootcamp2024Dates: September 4-5, 2024 from 08:00 AM - 3:30 PM each day
Target Audience: This course is designed for nurse practitioners and physician assistants working in critical care.
Location: Loews Vanderbilt Hotel located at 2100 West End Ave, Nashville, TN
Registration: https://www.eventbrite.com/e/vumc-critical-care-acnppa-bootcamp-2024-tickets-830345073467?utm-campaign=social&utm-content=attendeeshare&utm-medium=discovery&utm-term=listing&utm-source=cp&aff=ebdsshcopyurl
More Info: https://www.vumc.org/advanced-practice-critical-careIf you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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Episode 42! In this episode we foray into weight lifting and body building as we talked about amino acids for kidney protection after cardiac surgery (PROTECTION) and cycling in addition to PT in mechanically ventilated adults (CYCLE). We also feature our first real ad for the Critical Care ACNP/PA Bootcamp! Details below!
Bagging vs Ventilator During Cardiac Arrest: https://journal.chestnet.org/article/S0012-3692(24)00248-4/abstract
PROTECTION: https://www.nejm.org/doi/full/10.1056/NEJMoa2403769
PROTECTION (pubmed): https://pubmed.ncbi.nlm.nih.gov/38865168/
CYCLE: https://evidence.nejm.org/doi/10.1056/EVIDoa2400137
CYCLE (pubmed): https://pubmed.ncbi.nlm.nih.gov/38865147/
Bootcamp Details:
Vanderbilt University Medical Center is hosting its annual Critical Care ACNP/PA Bootcamp. This multi-specialty conference is designed for nurse practitioners and physician assistants working in critical care. The program, now in its thirteenth year, features a mix of lectures, roundtable discussions, expert Q&A sessions and networking opportunities aimed at both new and experienced providers. #CCBootcamp2024Dates: September 4-5, 2024 from 08:00 AM - 3:30 PM each day
Target Audience: This course is designed for nurse practitioners and physician assistants working in critical care.
Location: Loews Vanderbilt Hotel located at 2100 West End Ave, Nashville, TN
Registration: https://www.eventbrite.com/e/vumc-critical-care-acnppa-bootcamp-2024-tickets-830345073467?utm-campaign=social&utm-content=attendeeshare&utm-medium=discovery&utm-term=listing&utm-source=cp&aff=ebdsshcopyurl
More Info: https://www.vumc.org/advanced-practice-critical-careIf you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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Episode 41! We continue our CCR24 recap with a brief overview and thoughts on the conference as a whole and then dive into REVISE or "Stress Ulcer Prophylaxis during
Invasive Mechanical Ventilation" published by Cook et al in NEJM June 2024. Not the sexiest of all the topics but important nonetheless (and we will get to the others soon!)
REVISE: https://pubmed.ncbi.nlm.nih.gov/38875111/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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Episode 40! In this special episode releasing at the conclusion of the PREOXI presentation at the Critical Care Reviews 2024 conference in Belfast, Ireland - we discuss the recently published PREOXI trial evaluating NIV vs facemask as pre-oxygenation for emergent endotracheal intubation. Kevin Gibbs, the first author and presenter at the conference, is our special guest.
Stay tuned for our review of some of the other results from the conference!If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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Episode 39! In this episode we talk about steroids in septic shock from community acquired pneumonia - a secondary from the APROCCHSS trial. We then dive into our mailbag to talk about a couple of topics we've been asked questions about and address them in a more broad sense. A pseudo-mailbag but with real answers
APROCCHSS-CAP: https://pubmed.ncbi.nlm.nih.gov/38310918/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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We're live from ATS! We decide to format our episode after the NEJM/JAMA/ATS combined session and talk about the articles presented there. Some of them we've talked about before but provide new insights from listeners and questions from the audience. Some of them are new and we provide our thoughts from the presentations (not enough time to fully read the articles)
The one article we skip is ASTER that was published in JAMA by Ware et al during the conference. We want to spend a little more time on that one (and potentially have an author as a guest)! Stay tuned!If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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Episode 37! In this episode we talk about glycemic control in the ICU. We liked the flipped script and so we're again going old article first. NICE-SUGAR or "Intensive versus conventional glucose control in critically ill patients" was published in NEJM 2009 and then we talk about TGC-Fast or "Tight Blood-Glucose Control without Early Parenteral Nutrition in the ICU" published NEJM September of 2023
NICE SUGAR: https://pubmed.ncbi.nlm.nih.gov/19318384/
TGC-Fast: https://pubmed.ncbi.nlm.nih.gov/37754283/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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Episode 36! In this episode we talk about tranexamic acid in GI bleeds. We flip the script a little bit and talk about our OLD article first, HALT-IT or "Tranexamic acid in upper gastrointestinal bleed in patients with cirrhosis: A randomized controlled trial" published in Lancet in 2020. This sets the stage for our new trial "Tranexamic acid in upper gastrointestinal bleed in patients with cirrhosis" published in Kumar et al in Hepatology (a new journal for us!)
HALT-IT: https://pubmed.ncbi.nlm.nih.gov/32563378/
TXA and cirrhosis: https://pubmed.ncbi.nlm.nih.gov/38441903/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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Episode 35! In this episode we talk about extubation practices with "Effect of aggressive vs conservative screening and confirmatory test on time to extubation among patients at low or intermediate risk: a randomized clinical trial" published in Intensive Care Medicine by Hernandez et al. We then talk about an observation study by Zarrabian et al published in the Blue Journal "Liberation from Invasive Mechanical Ventilation with Continued Receipt of Vasopressor Infusions".
SPEED UP: https://pubmed.ncbi.nlm.nih.gov/38353714/
Extubation on Pressors: https://pubmed.ncbi.nlm.nih.gov/35107416/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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Episode 34! In this episode we talk about oxygen targets! Specifically we go over the two oxygen target analyses that were published simultaneously with ISICEM. We spend most of our time with HOT-COVID published by Nielson et al and then dip a little into individualized treatment effects of oxygen targets published by Buell et al - both published in JAMA March 2024. The latter is a complex topic and we hit some of the high points but please reach out to us if you want a more in depth discussion!
HOT-COVID: https://pubmed.ncbi.nlm.nih.gov/38501214/
Individualized Treatment Effects: https://pubmed.ncbi.nlm.nih.gov/38501205/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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Episode 33! In this episode we are excited to be joined by Eddy Fan and Whitney Gannon, two extraordinary ECMO researchers to talk about VENT-AVOID or " Extracorporeal Carbon Dioxide Removal to Avoid Invasive Ventilation During Exacerbations of Chronic Obstructive Pulmonary Disease" published March 2024 by Duggal et al in the ATS Blue Journal.
VENT-AVOID: https://pubmed.ncbi.nlm.nih.gov/38261630/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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Episode 32! We got a lot of feedback on our last episode so we decided to address it in a full episode! A lot of listeners asked us about vasopressors specifically vasopressin and angiotensin-2 so we talk about VASST, VANISH, and ATHOS-3. It is a full episode but a good one!
VASST: https://pubmed.ncbi.nlm.nih.gov/18305265/
VANISH: https://pubmed.ncbi.nlm.nih.gov/27483065/
ATHOS-3: https://pubmed.ncbi.nlm.nih.gov/28528561/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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Episode 31! This episode we talk first about invasive vs non-invasive blood pressures from an observational paper titled "Accuracy of Noninvasive Blood Pressure Monitoring in Critically Ill Adults" published in journal of Intensive Care Medicine by Haber et al and then for our old trial we further the discussion of blood pressure by talking about the 65 trial!
Non-invasive vs invasive blood pressure: https://pubmed.ncbi.nlm.nih.gov/38215002/
65 Trial: https://pubmed.ncbi.nlm.nih.gov/32049269/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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Episode 30! This episode is a little different. We recap the SCCM conference first. THEN we go into PROPHY-VAP or "Ceftriaxone to prevent early ventilator-associated pneumonia in patients with acute brain injury" published January 2024 by Professor Dahyot-Fizelier in Lancet Respiratory Medicine. Then we dive into our long neglected mailbag to review listener questions about MINT, intubation timing, ACORN, and all the steroids in ARDS talk
PROPHY-VAP: https://pubmed.ncbi.nlm.nih.gov/38262428/
SCCM Steroid guidelines: https://pubmed.ncbi.nlm.nih.gov/38240492/
Counter-Point should we use steroids in ARDS: https://pubmed.ncbi.nlm.nih.gov/33422201/
sRAGE in NIV and HFNC: https://pubmed.ncbi.nlm.nih.gov/38250011/
Anaerobes in Aspiration: https://pubmed.ncbi.nlm.nih.gov/37250794/
Anaerobes in Gut: https://pubmed.ncbi.nlm.nih.gov/36229047/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
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