Episodes
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In this episode, host Shikha Jain, MD, speaks with Brian Fiske about bringing biotech business ideas to fruition, antibody drug conjugate developments and more.
• Welcome to another exciting episode of Oncology Overdrive 0:14
• About Fiske 0:21
• The interview 1:45
• How did you get to where you are today, and how did you become interested in this specific area of health care? 2:06
• What is a timeline from start to finish to bringing an innovative idea to fruition? 6:01
• How long does it take to form an actual company from an idea? 11:20
• How do you figure out who you need on your team to move an idea forward? 15:11
• Tell us about your previous positions at biotech companies, and how did they help lead you into your current space? 20:22
• What excites you about your job? […] Why do you feel the drive and desire to do this type of work? 24:40
• Where do you see the work at Mythic Therapeutics doing in the next five to ten years for patient care? 26:27
• How can we work towards making sure this type of innovative work is available and accessible to patients? 29:20
• If someone could only listen to the last few minutes of this episode, what would you want them to take away? 31:16
• How to contact Fiske 32:12
• Thanks for listening 32:56
Brian Fiske is chief scientific officer and co-founder of Mythic Therapeutics, a clinical-stage biotechnology company committed to the development of next-generation antibody-drug conjugate therapies for the treatment of a wide range of cancers.We’d love to hear from you! Send your comments/questions to Dr. Jain at [email protected]. Follow Healio on X and LinkedIn: @HemOncToday and https://www.linkedin.com/company/hemonctoday/. Follow Dr. Jain on X: @ShikhaJainMD. Fiske can be reached via LinkedIn or the Mythic Therapeutics website.
Disclosures: Jain and Fiske report no relevant financial disclosures. -
On this special edition episode, Shikha Jain, MD, with Physicianary’s Hansa Bhargava, MD, and Mend the Gap’s Dagny Zhu, MD, discuss the evolution of empowering yourself and others and advocacy with a panel of guests.
• Intro 1:01
• What does it mean to empower women in medicine, and what are the ways that we can really empower others to achieve the things that they may not see for themselves? 2:39
• What are some ways in which you have empowered or hope to empower women in medicine? Are there tips or skills that have worked well? 5:43
• How have you been empowered by others, or have helped others find their voices? 8:38
• Do you agree that the conversation is changing toward a cultural shift in empowerment for women in health care? 13:53
• What are some challenges facing advocacy and empowerment? What do you do when your advocacy work is not being received or it is a struggle to speak up for someone? 18:40
• Emphasizing the importance of communication in advocacy work. 24:00
• Intro to Physicianary’s part 3 on physician burnout and work-life balance. 24:16
• Thanks for listening 25:00
Vineet Arora, MD, MAPP (NAM), is a Herbert T. Abelson professor of medicine, vice dean of education in the biological sciences division and dean for medical education at the University of Chicago Pritzker School of Medicine. She is also an elected member of the National Academy of Medicine. She is a founding member of the 501c3 Women of Impact and advisor to the Women in Medicine Summit.
Jennifer Bepple, MD, MMCi, is a double board-certified physician in urology and informatics. She is a member of the American Telemedicine Association, American Urologic Association and American Medical Informatics Association and holds a certification from the American Board of Telehealth and the American Board of AI in Medicine.
Hansa Bhargava, MD, is Healio's chief clinical strategy and innovation officer. Listen to her Healio podcast, Physicianary.
Shikha Jain, MD, FACP, is a board-certified hematology and oncology physician. She is a tenured associate professor of medicine in the division of hematology and oncology, the director of communication strategies in medicine and the associate director of oncology communication & digital innovation at the University of Illinois Cancer Center in Chicago.
Mara Schenker, MD, FACS, FAOA, is an orthopedic trauma surgeon at Grady Memorial Hospital. She is double board certified in orthopedic surgery and clinical informatics. She serves as the chief of orthopedics and associate chief medical information officer. She is an associate professor of orthopedics at Emory University School of Medicine. She serves on multiple boards for medical and digital technology advisory and sits on major national committees for the American Academy of Orthopaedic Surgeons, AAMC, American College of Surgeons and the Orthopaedic Trauma Association.
Dagny Zhu, MD, is a cornea, cataract and refractive surgeon and medical director and partner at NVISION Eye Centers in Rowland Heights, CA. She can be reached on X @DZEyeMD.
We’d love to hear from you! Send your comments/questions to Dr. Jain at [email protected]. Follow Healio on X and LinkedIn: @HemOncToday and https://www.linkedin.com/company/hemonctoday/. Follow Dr. Jain on X: @ShikhaJainMD.
Disclosures: The hosts and guest report no relevant financial disclosures. -
Missing episodes?
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In this special 100th episode, host Shikha Jain, MD, speaks with her father, Krishna Jain, MD, about work-life balance pertaining to private practice, improving a fragmented health care system and more.
• Welcome to another exciting episode of Oncology Overdrive 1:18
• About Krishna Jain 1:27
• The interview 2:27
• How did you end up in the United States? What was your journey to becoming a world-renowned vascular surgeon? 2:44
• What was it like being a resident back then, especially as someone who came from abroad? 7:30
• After training, why didn’t you go back to India? 10:12
• Shikha Jain on how her father inspired her passion for research and mentorship. 13:19
• Why did you choose to go into private practice, and how did you build your practice and become a leader in this space? 15:18
• The Jains on the importance of being present for and supporting family. 19:16
• How did your entrepreneurial life start? 23:55
• What do your limb preservation centers do? 27:33
• What are some things that need to be done to improve our fragmented health care system? 29:45
• What led you found the South Asian American Vascular Society? 34:16
• How did you end up deciding to go to Kalamazoo, MI instead of going back to India? 39:11
• What are most proud of in your career? 41:28
• What do you want to share with the next generation of surgeons and physicians? 44:07
• The Jains on their relationship growing up and now. 45:44
• If someone could only listen to the last minute of this episode, what would you want them to take away? 47:48
• How to contact Jain 48:48
• Thanks for listening 50:43
Krishna Jain, MD, is a vascular surgeon who has been intimately involved in the growth of office based endovascular centers throughout the country since 2007.We’d love to hear from you! Send your comments/questions to Dr. Jain at [email protected]. Follow Healio on X and LinkedIn: @HemOncToday and https://www.linkedin.com/company/hemonctoday/. Follow Dr. Jain on X: @ShikhaJainMD. Krishna Jain can be reached via email [email protected].
Disclosures: Jain reports no relevant financial disclosures. -
In this special throwback episode, Shikha Jain, MD, talks with Olympic champion Kikkan “Kikkanimal” Randall, about how her positive attitude and athlete mentality have helped her navigate a breast cancer diagnosis and treatment, valuable advice for both oncologists and patients and more.
• Intro 1:44
• About Randall 1:58
• The interview 3:22
• Tell us a bit about you. Who are you? How did you get to where you are and how did you decide you wanted to be a part of the U.S. Olympic cross-country ski team? 3:51
• How were you diagnosed? 6:12
• How old were you when you first realized that you had this pebble in your breast? 7:33
• What type of mentality is it that makes you such a phenomenal Olympic athlete that you were able to translate into this taking charge of your health and taking charge of your cancer as you move forward? 9:20
• What was the best way for you to cope as you felt this loss of control going through your treatment in certain times? 12:09
• What did you do to prepare for your clinic visits when you were trying to advocate for yourself? 16:17
• Can you talk more about the video blog you kept during treatment? 17:55
• How did you navigate the disease with your son? 21:50
• How long do they recommend for you to wait to try again (to conceive)? Did you have those conversations? 26:17
• Do you feel like you are mentally approaching this period of your post-cancer care or your post-treatment time? 29:58
• Randall running a marathon following the completion of her treatment 32:07
• How did you get involved with Healthy Futures and Fast and Female, and what exactly do they do? 38:08
• Did the way that you participate in advocacy change after you were diagnosed with cancer? 42:46
• One thing you wish oncologists knew when they are treating patients with any kind of cancer, and one thing patients should know if they’re newly diagnosed? 48:09
• How to find Randall 50:26
• Thanks for listening 51:58
Kikkan Randall is an Olympic champion, active mom, cancer fighter and “Get-Activist.”
We’d love to hear from you! Send your comments/questions to Dr. Jain at [email protected]. Follow Healio on X and LinkedIn: @HemOncToday and https://www.linkedin.com/company/hemonctoday/. Follow Dr. Jain on X: @ShikhaJainMD. Randall can be reached at kikkan.com.
Disclosures: Jain reports no relevant financial disclosures. -
In this episode, host Shikha Jain, MD, speaks with Shyam Natarajan, PhD, about machine learning in cancer research and testing, using technological innovation to address disparities in health care trials and more.
• Welcome to another exciting episode of Oncology Overdrive 1:17
• About Natarajan 1:22
• The interview 2:10
• How did you get into the medical technology space? 2:29
• Can you explain what machine learning means? 4:37
• How did you end up co-founding Avenda Health? 7:18
• Do you think that this type of technology is replicable in other disease types as well? […] Where else do you see this being a benefit? 9:53
• When you think about AI, what are the other applications for this type of technology outside of oncology? 11:24
• How do you respond to concerns that AI is becoming too sentient or independent? 12:50
• What are the checkpoints we need to put in place to make sure that biases in AI algorithms do not become the norm? 16:21
• Do you have ways to predict who would benefit from these types of technology, and can you categorize patients into who is appropriate for trialing these technologies? 19:44
• Is there a way to utilize this technology to address disparities in health care? 22:04
• Have you found that there are specific things that make it harder to enroll patients in these particular clinical trials? How do you navigate those? 24:47
• If you had a crystal ball that could see fifty years into the future, where do you see all of this technology going? 27:28
• If someone could only listen to the last few minutes of this episode, what would you want them to take away? 30:56
• How to contact Natarajan 31:31
• Thanks for listening 32:22
Shyam Natarajan, PhD, is the co-founder and CEO of Avenda Health, a medtech company focused on improving outcomes for the one in seven men at risk for prostate cancer.We’d love to hear from you! Send your comments/questions to Dr. Jain at [email protected]. Follow Healio on X and LinkedIn: @HemOncToday and https://www.linkedin.com/company/hemonctoday/. Follow Dr. Jain on X: @ShikhaJainMD. Natarajan can be reached at www.avendahealth.com or via LinkedIn.
Disclosures: Jain and Natarajan report no relevant financial disclosures. -
In this episode, host Shikha Jain, MD, speaks with Komal Jhaveri, MD, about breakthroughs in breast cancer treatment, where the field is evolving with anti-body drug conjugates and more.
• Welcome to another exciting episode of Oncology Overdrive 1:17
• About Jhaveri 1:21
• The interview 1:41
• How did you get into this highly specialized field? […] How did you become a breast oncologist and find yourself at Memorial Sloan Kettering? 2:07
• As a breast oncologist, what has really excited you in the breast cancer space over the last decade? 5:02
• What do you think is going to happen in the next five to twenty years? Where do you think breast cancer treatment is going to evolve? 13:44
• Do you think AI is going to have a big impact on how we treat patients? 17:47
• If someone could only listen to the last minute of this episode, what would you want them to take away? 19:52
• How to contact Jhaveri 20:34
• Thanks for listening 21:32
Komal Jhaveri, MD, is a breast oncologist & early drug development specialist, clinical director of the early drug development service, and section head of the endocrine therapy research program at Memorial Sloan Kettering Cancer Center (MSK).We’d love to hear from you! Send your comments/questions to Dr. Jain at [email protected]. Follow Healio on X and LinkedIn: @HemOncToday and https://www.linkedin.com/company/hemonctoday/. Follow Dr. Jain on X: @ShikhaJainMD. Jhaveri can be reached at her office 646-888-5157, or via email [email protected].
Disclosures: Jain reports no relevant financial disclosures. Jhaveri reports she is the principal investigator for Genentech’s INAVO120 trial at MSK and co-chair globally. -
In this episode, host Shikha Jain, MD, speaks with David Cosgrove, MD, about implementing real-world utilization of clinical trials, the importance of diversity in clinical trials and more.
• Welcome to another exciting episode of Oncology Overdrive 1:17
• About Cosgrove 1:26
• The interview 2:54
• How did you make your way from Ireland to Portland, Oregon? 3:18
• As a fellow GI oncologist, what are you excited about in the cancer research space? 6:13
• How can we realistically address disparities in cancer care to deliver the latest breakthroughs to patients? 8:54
• Jain and Cosgrove on the challenges GI cancers experience in terms of delivery of cancer care compared to colleagues in other spaces. 11:22
• What excites you about what’s happening in oncology right now, and where we’re going in this space? 13:30
• How did you end up as medical director at Compass Oncology? 15:15
• What are you specifically working on now, and where do you hope to see it go in the next five years? 17:25
• How do we get more patients from different backgrounds into clinical trials, and why is it important that we do that? 19:05
• Jain and Cosgrove on challenges facing patient guidelines and qualifications for clinical trials. 21:09
• If someone could only listen to the last few minutes of this episode, what would you want them to take away? 23:41
• How to contact Cosgrove 24:45
• Thanks for listening 25:49
David Cosgrove, MD, serves as the medical director of Compass Oncology in Portland, Oregon, and specializes in general adult oncology with advanced subspecialty expertise in gastrointestinal cancers.We’d love to hear from you! Send your comments/questions to Dr. Jain at [email protected]. Follow Healio on X and LinkedIn: @HemOncToday and https://www.linkedin.com/company/hemonctoday/. Follow Dr. Jain on X: @ShikhaJainMD. Cosgrove can be reached via email [email protected].
Disclosures: Jain and Cosgrove report no relevant financial disclosures. -
In this episode, host Shikha Jain, MD, speaks with MOLLI Surgical co-founder and CEO, Ananth Ravi, about inventing surgical technology to provide better patient care, addressing inequities in surgical tool access and more.
• Welcome to another exciting episode of Oncology Overdrive 1:15
• About Ravi 1:27
• The interview 2:10
• Tell me about how entered this field and how you ended up founding a company that invents surgical instruments. 2:42
• How did you end up moving from Zambia to Canada? 5:02
• Tell me more about MOLLI Surgical. How is this precision surgery unique from what is already out there? 6:47
• What is your background to help you go from ideation to implementation, and how did you take the steps to make your ideas a reality? 10:31
• How do you address rural and global disparities when it comes to accessing these technologies? 16:12
• In an ideal world, where would you see this technology being utilized, and are there any other technologies that you think will revolutionize this type of care? 19:32
• What else excites you about this space? […] How did you find going from the academic space into this role in the business/corporate space? 22:19
• Jain and Ravi on work-life balance. 25:51
• What’s next for you in the next three to five years? 29:26
• If someone could only listen to the last few minutes of this episode, what would you want them to take away? 30:15
• How to contact Ravi 30:42
• Thanks for listening 31:39
Ananth Ravi is president, CEO and co-founder of MOLLI Surgical.We’d love to hear from you! Send your comments/questions to Dr. Jain at [email protected]. Follow Healio on X and LinkedIn: @HemOncToday and https://www.linkedin.com/company/hemonctoday/. Follow Dr. Jain on X: @ShikhaJainMD. Ravi can be reached at www.mollisurgical.com or via email [email protected].
Disclosures: Jain reports no relevant financial disclosures. Ravi reports he is president, CEO and co-founder of MOLLI Surgical. -
In this episode, host Shikha Jain, MD, speaks with Cyclacel CEO, Spiro Rombotis, MPH, about developing techniques and therapies for drug development, how technology has affected these advancements and more.
• Welcome to another exciting episode of Oncology Overdrive 1:15
• About Rombotis 1:23
• The interview 2:21
• Can you tell us about how you ended up in the biotech and pharma spaces? 2:41
• How did you transition to the first CEO of Cyclacel, and what has kept you in the same space for over three decades? 4:45
• Is this how you envisioned your career? How did this vision evolve over the course of your career? 8:53
• What does Cyclacel do, and can you describe the types of innovation you are doing there? 10:19
• With all this new and exciting technology in the field, where do you see epigenetics and precision oncology going in the next ten to twenty years? 15:46
• What are your thoughts on AI in the oncology space? 22:21
• Jain and Rombotis on checks and balances when it comes to AI use in cancer care and clinical trials. 27:53
• What’s next for you? 30:53
• If someone could only listen to the last few minutes of this episode, what would you want them to take away? 36:18
• How to contact Rombotis 40:25
• Thanks for listening 40:43
Spiro Rombotis, MPH, is the CEO of Cyclacel. He has over 36 years at three public biotechs and two pharmas.We’d love to hear from you! Send your comments/questions to Dr. Jain at [email protected]. Follow Healio on X and LinkedIn: @HemOncToday and https://www.linkedin.com/company/hemonctoday/. Follow Dr. Jain on X: @ShikhaJainMD. Rombotis can be reached via email [email protected].
Disclosures: Jain reports no relevant financial disclosures. Rombotis reports Cyclacel Ltd employment and stock ownership. -
In this episode, host Shikha Jain, MD, speaks with Jennifer Michaelson, PhD, about how to seek out opportunities in the health care industry, making space for diversity in biotech innovation and more.
• Welcome to another exciting episode of Oncology Overdrive 1:15
• About Michaelson 1:21
• The interview 2:30
• Can you tell us about how you ended up in the biotech executive space? 2:47
• How do people get involved in this type of work? 12:32
• Tell us about sourcing innovation in biotech, along with the challenges that come with it. 16:46
• How do you consider patient access when thinking about innovations in the biotech space? 21:15
• When you think about the challenges facing leadership and diversity in these spaces, how can we create an inclusive culture in the health care space? What have you done to spearhead a culture of DEI? 23:51
• Jain and Michaelson on organizations infusing DEI concepts into standards of practice and care. 30:58
• If someone could only listen to the last minute of this episode, what would you want them to take away? 32:16
• How to contact Michaelson 33:52
• Thanks for listening 34:23
Jennifer Michaelson, PhD, is chief scientific officer at Cullinan Therapeutics. Michaelson is a biotech executive with 20+ years of industry experience in oncology, immunology, and immune-oncology drug development.We’d love to hear from you! Send your comments/questions to Dr. Jain at [email protected]. Follow Healio on X and LinkedIn: @HemOncToday and https://www.linkedin.com/company/hemonctoday/. Follow Dr. Jain on X: @ShikhaJainMD. Michaelson can be found on LinkedIn or via email [email protected].
Disclosures: Jain and Michaelson report no relevant financial disclosures. -
In this episode, host Shikha Jain, MD, speaks with Sean Bohen, MD, about how cancer therapies are changing how oncology can be discussed, shifting from clinical to industry work and more.
• Welcome to another exciting episode of Oncology Overdrive :58
• About Bohen 1:04
• The interview 1:30
• Tell us about your journey. How did you become an oncologist, and how did you make the transition into working in the pharmaceutical industry? 1:51
• How did you end up at Olema Oncology after working with other pharmaceutical companies? What was your decision-making process to focus on the industry part of your career? 3:44
• Tell us more about what Olema Oncology does and what your role is there. 6:30
• What do you see coming down the pipeline for breast cancer research and innovation? … What do you think Olema will contribute to that space? 8:58
• Bohen and Jain on the ways in which new treatments have resulted in shifting conversations around cancer care and patient quality of life. 12:45
• If someone in fellowship is interested in working in industry, pharmaceuticals or scientific development, what are the most effective ways to get into this space? 18:21
• Jain and Bohen on changing the mindset and misconceptions around moving between clinical, academic and industry work within the field and after fellowship. 20:52
• What do you see happening in the oncology landscape twenty years from now? 25:46
• If someone could only listen to the last two minutes of this episode, what would you want them to take away? 29:19
• How to contact Bohen 30:54
• Thanks for listening 31:52
Sean Bohen, MD, is the President and CEO of Olema Oncology.We’d love to hear from you! Send your comments/questions to Dr. Jain at [email protected]. Follow Healio on X and LinkedIn: @HemOncToday and https://www.linkedin.com/company/hemonctoday/. Follow Dr. Jain on X: @ShikhaJainMD. Bohen can be reached at olema.com.
Disclosures: Jain and Bohen report no relevant financial disclosures. -
In this episode, host Shikha Jain, MD, speaks with Jonathan D. Licht, MD, about becoming and training qualified leaders in the field, challenges facing health care leaders and more.
• Welcome to another exciting episode of Oncology Overdrive :58
• About Licht 1:16
• The interview 3:17
• Can you tell us about your journey into hematology-oncology and how you ended up where you are today? 3:58
• How have you found the time and ability to balance and succeed in the research, clinical, translational and leadership parts of your work? 9:05
• What do you suggest to people who are currently trying to get into leadership positions in their early-to-mid career? 12:52
• Do you agree with the sentiment that there are some leaders in the field who are put into positions prematurely or are ineffective? As a leader, how do you address the need for further training of future leaders? 18:39
• What are some of the leadership challenges you have seen in the last several years, and how have you managed to navigate them? 23:20
• How did you use your leadership skills to navigate the first few years of the pandemic, and how are you continuing to navigate delivery of care post-pandemic? 29:23
• Tell me about the process of achieving NCI designation and what it means for your institution. 36:25
• How have you had to navigate state health care legislation and policies challenging reproductive health care? 42:16
• If someone could only listen to the last minute of this episode, what would you want them to take away? 46:13
• How to contact Licht 46:56
• Thanks for listening 48:16
Jonathan D. Licht, MD, is the director of the University of Florida Health Cancer Center.We’d love to hear from you! Send your comments/questions to Dr. Jain at [email protected]. Follow Healio on X, formerly known as Twitter, and LinkedIn: @HemOncToday and https://www.linkedin.com/company/hemonctoday/. Follow Dr. Jain on X, formerly known as Twitter: @ShikhaJainMD. Licht can be reached on X, formerly known as Twitter, @jdlicht or via email [email protected].
Disclosures: Jain reports no relevant financial disclosures. Licht reports consultancy for AstraZeneca and research funding for Epizyme. -
In this episode, host Shikha Jain, MD, speaks with Aparna Parikh, MD, about cancer and GI malignancies in the global health space, circulating tumor DNA in the field of oncology and more.
• Welcome to another exciting episode of Oncology Overdrive :58
• About Parikh 1:07
• The interview 2:08
• What was your path into medicine, cancer care and GI oncology? 2:35
• Tell us about what you do in the global health space and what your thoughts are on colon cancer and GI malignancies in the global health space. 8:07
• Why are we seeing so many more young people being diagnosed with colon cancer in the US and internationally? 12:24
• Do you think US lifestyle and Western diets compared to the rest of the world have contributed to the rise of early colon cancer diagnoses? 15:04
• How can physicians talk about lifestyle, diet and environmental/social determinants of health that impact a cancer diagnosis? 17:52
• Can you provide a brief overview of what is circulating tumor DNA (ctDNA) and liquid biopsy, and how are we using it in this space? 19:44
• Jain and Parikh on ctDNA as an innovation can be transformative in the field of GI oncology. 24:06
• What are your predictions for GI oncology in the next ten to twenty years? 26:06
• If someone could only listen to the last few minutes of this episode, what would you want them to take away? 28:44
• How to contact Parikh 30:57
• Thanks for listening 31:57
Aparna Parikh, MD, is a GI oncologist at the MGH Cancer Center where she directs the colorectal research program and young adults CRC program. She is an associate professor at Harvard Medical School and an international expert in CRC and liquid biopsies.We’d love to hear from you! Send your comments/questions to Dr. Jain at [email protected]. Follow Healio on X, formerly known as Twitter, and LinkedIn: @HemOncToday and https://www.linkedin.com/company/hemonctoday/. Follow Dr. Jain on X, formerly known as Twitter: @ShikhaJainMD. Parikh can be reached via email [email protected].
Disclosures: Jain reports no relevant financial disclosures. Parikh reports equity in C2i Genomics XGenomes Cadex and Parithera. Advisor/consultant for Abbvie, AZ, Bayer, Biofidelity, Checkmate Pharmaceuticals, CVS, Delcath, Eli Lilly, FMI, Guardant, Hookipa, Illumina, Inivata, Mirati, Pfizer, Saga, Seagen, Taiho, Scare Inc, Science For America, and Value Analytics Lab. She receives fees from Up to Date. She has received travel fees from Karkinos Healthcare. She has been on the DSMC for a Roche study and on Steering Committee for Exilixis. She has received research funding to the Institution from BMS, Daiichi Sankyo, Erasca, Genentech, Mirati, Novartis, PMV Pharmaceuticals, Plexxicon, PureTech, Takeda and Syndax. -
In this episode, host Shikha Jain, MD, speaks with Barnaby Balmforth, PhD, about the evolution of genomics in cancer care, the impact of personalized care tools and more.
• Welcome to another exciting episode of Oncology Overdrive :58
• About Balmforth 1:12
• The interview 3:01
• How did you get to where you are today? What drove you to become a leader in this space? 3:45
• What is genomics, and why is genomic analysis important in cancer care? 7:18
• Jain and Balmforth on the evolution of technology and challenges facing genomics and diagnostic testing to achieve personalized care for individual patients. 11:59
• In addition to time, can you speak on the challenge of access for this type of technology? 13:20
• How have you been able to implement “next day” test results and reports of your technology? 17:50
• Jain and Balmforth on how Biofidelity’s technology can transform the delivery of care, as well as its psychological and mental impact. 19:06
• What’s coming down the line for you and Biofidelity? 20:56
• What are your thoughts for when you expand beyond thoracic oncology? What are your long-term visions for other disease sites? 24:19
• Do you have any thoughts on AI and how it may influence genomics in cancer care? 25:51
• If someone could only listen to the last few minutes of this episode, what would you want them to take away? 28:37
• How to contact Balmforth 30:37
• Thanks for listening 31:10
Barnaby Balmforth, PhD, is co-founder and CEO of Biofidelity. Barnaby has more than 15 years’ experience in the leadership of multidisciplinary technology development.We’d love to hear from you! Send your comments/questions to Dr. Jain at [email protected]. Follow Healio on X, formerly known as Twitter, and LinkedIn: @HemOncToday and https://www.linkedin.com/company/hemonctoday/. Follow Dr. Jain on X, formerly known as Twitter: @ShikhaJainMD. Balmforth can be reached via the Biofidelity website.
Disclosures: Jain reports no relevant financial disclosures. Balmforth reports he is an employee of Biofidelity and owns shares in the company. -
In this episode, host Shikha Jain, MD, speaks with Christina Gomez, MD, about the power of patients’ voices, finding joy in physicians work-life balance and more.
• Welcome to another exciting episode of Oncology Overdrive :58
• About Gomez 1:09
• The interview 1:45
• How did you get to where you are today as a GI oncologist? 2:02
• Have you seen an increase in young people with GI malignancies, and do you have any thoughts as to why we are seeing this change? 5:23
• Where did the inspiration for your book, Stopped in My Tracks: A Physician's Collection of Cancer Patients' Quotes, come from? 9:08
• Jain and Gomez on the power of patient voices. 12:41
• Thoughts on creating another book? 15:30
• Where do you see the landscape of oncology going in the age of machine-learning and new technologies? 17:05
• Jain and Gomez on the different ways physicians can demonstrate personalized care for patients. 21:00
• What should we do as oncologists and as a society to prevent burnout in health care professionals? 24:00
• Jain and Gomez on the mindset shift on work-life-balance for physicians. 27:33
• Jain and Gomez on motherhood and how it can define patient interactions and delivery of care. 29:51
• If someone could only listen to the last few minutes of this episode, what would you want them to take away? 34:41
• How to contact Gomez 36:07
• Thanks for listening 37:31
Christina Gomez, MD, is a gastrointestinal medical oncologist at Banner MD Anderson Cancer Center.
We’d love to hear from you! Send your comments/questions to Dr. Jain at [email protected]. Follow Healio on X, formerly known as Twitter, and LinkedIn: @HemOncToday and https://www.linkedin.com/company/hemonctoday/. Follow Dr. Jain on X, formerly known as Twitter: @ShikhaJainMD. Gomez can be reached at christinagomezmd.com, via Facebook or on Instagram @christygomezmd.
Disclosures: Jain and Gomez report no relevant financial disclosures. -
In this episode, host Shikha Jain, MD, speaks with Ashley Sumrall, MD, about advocacy outside of their oncology practices and organizations, what lies ahead for the field of neuro-oncology and more.
• Welcome to another exciting episode of Oncology Overdrive :58
• About Sumrall 1:16
• The interview 2:54
• How did you end up in the neuro-oncology space? 3:21
• As a neuro-oncologist, how do you stay up-to-date with neurology, oncology and medicine? 7:28
• Is there a difference in the way you interact with a neuro-oncologist versus a medical oncologist? 8:58
• What drove you to get into the advocacy space? 10:09
• Do you predominantly do advocacy work through ASCO, or do you do it through other avenues as well? 12:20
• If someone is interested in getting involved in becoming an advocate with ASCO, on the local level or on the national level, what is the best way for them to start that process? 15:24
• How do you talk to people in and outside of organizations about current situations facing health care? 19:40
• If people are interested in learning more about the AMA or getting involved with an organization like the AMA, how can they do so? 22:31
• What do you see coming down the pipeline that you think is going to transform the neuro-oncology space? 27:16
• If someone could only listen to the last minute of this episode, what would you want them to take away? 30:04
• How to contact Sumrall 32:13
• Thanks for listening 32:56
Ashley L. Sumrall, MD, is a neuro-oncologist practicing at Levine Cancer Institute in Charlotte, NC.
We’d love to hear from you! Send your comments/questions to Dr. Jain at [email protected]. Follow Healio on X, formerly known as Twitter, and LinkedIn: @HemOncToday and https://www.linkedin.com/company/hemonctoday/. Follow Dr. Jain on X, formerly known as Twitter: @ShikhaJainMD. Sumrall can be reached on X, formerly known as Twitter: @AshleySumrallMD.
Disclosures: Jain reports no relevant financial disclosures. Sumrall reports receiving funding from Bristol-Myers Squibb, Exelixis, Kura Oncology, Novocure and Oncoceutics, and being a consultant for Abbvie, Athenex, Bayer, Exelixis and Novocure. -
In this episode, host Shikha Jain, MD, speaks with George Sledge, MD, about patient feedback benefiting leadership decision-making, the future of precision medicine in oncology and more.
• Welcome to another exciting episode of Oncology Overdrive :58
• About Sledge 1:03
• The interview 2:59
• How did you become an oncologist? 3:24
• Tell us about your journey into leadership in oncology. 5:27
• Did you continue to see patients while leading organizations? 7:48
• Jain and Sledge on learning from conversations and experiences with patients. 10:57
• How did you end up in your previous position as ASCO president? 12:29
• Do you feel that ASCO is an organization that is adept at adapting to change? 14:37
• Tell us about Caris Life Sciences and how you pivoted to your role as executive vice president and CMO there. 18:44
• Where do you see the future of oncology going? 23:00
• Jain and Sledge on the concerns surrounding artificial intelligence and technology in cancer care and the doctor patient relationship. 26:31
• What is something aspirational that you think could change the way we deliver cancer care years from now? 31:11
• If someone could only listen to the last minute of this episode, what would you want them to take away? 35:21
• How to contact Sledge 36:37
• Thanks for listening 37:10
George Sledge, MD, serves as executive vice president and chief medical officer at Caris Life Sciences.
We’d love to hear from you! Send your comments/questions to Dr. Jain at [email protected]. Follow Healio on X, formerly known as Twitter, and LinkedIn: @HemOncToday and https://www.linkedin.com/company/hemonctoday/. Follow Dr. Jain on X, formerly known as Twitter: @ShikhaJainMD. Sledge can be reached via email [email protected].
Disclosures: Jain reports no relevant financial disclosures. Sledge reports that he has stock options with Syndax. -
In this episode, host Shikha Jain, MD, speaks with Jan Kitajewski, PhD, about blending community need with scientific advancement, his role as the director of a cancer care center and more.
• Welcome to another exciting episode of Oncology Overdrive :58
• About Kitajewski 1:08
• The interview 2:59
• Tell me about how you started and your pathway to this position. 3:26
• You have a very diverse background in various fields of medicine. Was there something that drew you to lead a cancer center? 6:15
• What are your thoughts on how institutions can shift their mindsets toward setting up research that is more inclusive of patient diversity in clinical trials? 9:44
• Jain and Kitajewski on The Immortal Life of Henrietta Lacks, mistrust in the health care system, and how institutions can empower their communities. 14:00
• What does a cancer center director do, and what are some things that people may be surprised to know about your position? 16:30
• Jain and Kitajewski on the University of Illinois Cancer Center applying for NCI designation, and what the process entails. 22:05
• Jain and Kitajewski on the challenges and successes that come with physician leadership when making changes at an institution. 29:28
• What is your vision for the future of the University of Illinois Cancer Center? 34:16
• If someone could only listen to the last minute of this episode, what would you want them to take away? 40:13
• How to contact Kitajewski 40:55
• Thanks for listening 41:35
Jan Kitajewski, PhD, is director of the University of Illinois Cancer Center and a professor and head of the department of physiology and biophysics.
We’d love to hear from you! Send your comments/questions to Dr. Jain at [email protected]. Follow Healio on X, formerly known as Twitter, and LinkedIn: @HemOncToday and https://www.linkedin.com/company/hemonctoday/. Follow Dr. Jain on X, formerly known as Twitter: @ShikhaJainMD. Kitajewski can be reached via email [email protected].
Disclosures: Jain reports no relevant financial disclosures. Healio could not confirm relevant financial disclosures for Kitajewski at the time of posting. -
In this episode, host Shikha Jain, MD, speaks with Avital O’Glasser, MD, about the challenges facing non-traditional scholarship, amplifying diverse voices in medicine and more.
• Welcome to another exciting episode of Oncology Overdrive :58
• About O’Glasser 1:15
• The interview 2:36
• Jain and O’Glasser on their friendship and how they met. 2:52
• What is non-traditional scholarship, and why is it so difficult for academics to adopt to these practices? 5:16
• Jain and O’Glasser on the added value of non-traditional scholarship in academia and engagement. 11:25
• How can engaging in non-traditional scholarship be leveraged and disseminated along with more “traditionally” recognized ways of CME? 13:33
• O’Glasser on Daniel Cabrera’s More Than Likes and Tweets: Creating Social Media Portfolios for Academic Promotion and Tenure and Ernest Boyer’s The Scholarship of Engagement. 17:19
• Jain and O’Glasser on utilizing digital abstracts in presenting data and pushing back on non-promotable work. 18:30
• How can physicians make sure that information reaches its desired audience through non-traditional scholarship, or provide more educational opportunities about this work? 22:29
• About An Evolution of Empowerment: Voices of Women in Medicine and Their Allies, co-edited by Jain and O’Glasser, and their process in creating this publication. 24:28
• Do you think we’ll collaborate on another book? 32:22
• If someone could only listen to the last few minutes of this episode, what would you want them to take away? 35:47
• How to contact O’Glasser 36:45
• Thanks for listening 38:08
Avital O’Glasser, MD, FACP, FHM, is a hospitalist and associate professor of medicine at Oregon Health & Science University. Her clinical practice focus is perioperative medicine, and she is also the assistant program director for social media and scholarship for OHSU’s Internal Medicine Residency Program.
We’d love to hear from you! Send your comments/questions to Dr. Jain at [email protected]. Follow Healio on X, formerly known as Twitter, and LinkedIn: @HemOncToday and https://www.linkedin.com/company/hemonctoday/. Follow Dr. Jain on X, formerly known as Twitter: @ShikhaJainMD. O’Glasser can be reached on the Women In Medicine blog.
Disclosures: Jain and O’Glasser report no relevant financial disclosures. -
In this episode, host Shikha Jain, MD, speaks with St. Jude’s Steven Gottschalk, MD, and Paulina Velasquez, MD, about the evolution of bone marrow transplant and cell therapy, increasing accessibility to CAR T-cell therapy and more.
• Welcome to another exciting episode of Oncology Overdrive :58
• About Gottschalk 1:12
• About Velasquez 1:57
• The interview 2:23
• About Gottschalk’s journey and how he ended up in this space. 2:56
• About Velasquez’s journey and how she ended up in this space. 4:16
• Gottschalk on the history of severe combined immune deficiency (SCID), or “bubble boy disease” and his work on developing the cure. 5:04
• When you think about what we have learned about immunotherapy, immune systems and cancer treatment over the last fifty years, did you think we would be where we are today in cancer care? 7:27
• How have CAR T-cells transformed health care so far, and what will they do for the future? 8:53
• What are you currently working on, and what excites you most about that work? 9:57
• Do you think that we can expect a transformation in CAR T-cells being used in solid tumors in the future? 12:34
• How do we prioritize enhanced CAR T-cells in clinical studies? 13:38
• How can we address the challenges facing the delivery of CAR T-cell therapy and make it more accessible to patients? 17:04
• Where do you see CAR T-cell therapy going in cancer care and in immunodeficiencies? 21:03
• If you were interviewed again in five years, what do you think you will be doing then, and what do you think we will be talking about? 25:42
• If someone could only listen to the last two minutes of this episode, what would you want them to take away? 30:31
• How to contact Gottschalk and Velasquez 31:22
• Thanks for listening 31:51Stephen Gottschalk, MD, St. Jude Department of bone marrow transplantation and cellular therapy chair, focuses his research on cancer immunotherapy, cell therapy and stem cell transplantation. The Gottschalk laboratory focuses on Epstein-Barr virus-specific T cells for treating EBV-associated cancers and using genetically modified T cells for cancer immunotherapy.
Paulina Velasquez, MD, St. Jude Department of bone marrow transplantation and cellular therapy, has made significant contributions to the field of immunotherapy, developing novel T-cell therapy platforms for pediatric hematological malignancies. Her team is pursuing projects that address antigen discovery, tumor immune evasion, persistence and efficacy of CAR T cells and cell-cell interaction within the tumor microenvironment.
We’d love to hear from you! Send your comments/questions to Dr. Jain at [email protected]. Follow Healio on X, formerly known as Twitter, and LinkedIn: @HemOncToday and https://www.linkedin.com/company/hemonctoday/. Follow Dr. Jain on X, formerly known as Twitter: @ShikhaJainMD. Gottschalk can be reached via email [email protected]. Velasquez can be reached via email [email protected].
Disclosures: Jain reports no relevant financial disclosures. Gottschalk reports he is co-inventor on patents and patent applications in the fields of cell or gene therapy for cancer, a member of the scientific advisory board of Be Biopharma and CARGO, and the data and safety monitoring board (DSMB) of Immatics and has received honoraria from TESSA Therapeutics. Velasquez reports patent applications in the field of T-cell immunotherapy.
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