Episodes

  • Most men think erectile dysfunction is a bedroom problem. It's actually one of the earliest warning signs of cardiovascular disease, capable of showing up three to five years before a heart attack.

    In this episode, Dr. Gabrielle Lyon sits down with Dr. Amy Pearlman, a urologist trained in men's sexual health, to discuss:

    Why ED is a symptom of vascular health, not a standalone disease and how the artery feeding the heart is roughly double the size of the one feeding the penis, so problems show up "down there" firstWhy "normal" testosterone can be meaningless, and the questions to ask before accepting a lab result that didn't flagHow daily erections preserve penile tissue the way water keeps a sponge supple and why disuse can cost noticeable size over just a few monthsThat cardiovascular exercise can rival ED medication for improving erectile function, making your heart health the real fixHow to track erectile fitness before there's a problem, instead of waiting until something breaks

    By the end, you'll understand the single signal your body uses to flag heart and metabolic risk early and the simple, mostly drug-free steps that protect both your cardiovascular health and your sexual function for life.

    Thank you to our sponsors:

    Manukora - Go to https://bit.ly/3RCMrKx to save 31% plus $25 worth of free gifts.Timeline - Get 20% off your Mitopure order at https://bit.ly/4dW6BGNBon Charge - Save 15% at https://bit.ly/433Xi2B with code DRLYON

    Explore More from Dr. Gabrielle Lyon

    Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/

    Listen to "Pearls of Wisdom" on all your favorite platforms!

    Spotify: https://open.spotify.com/show/4uOhWn5DeVXO7D2ppa0RoV

    Apple Podcasts: https://podcasts.apple.com/us/podcast/pearls-of-wisdom/id1617916659

    Find Dr. Amy Pearlman at:

    Website: https://www.primeinstitute.us/

    YouTube: https://youtube.com/@docamyurology?si=oJ2LZ_sxMPYTaK41

    Instagram: https://www.instagram.com/amypearlmanmd/

    X: https://x.com/AmyPearlman1

    LinkedIn: https://www.linkedin.com/in/amy-pearlman-54a2b0208

    Connect with Dr. Gabrielle Lyon:

    Instagram: https://www.instagram.com/drgabriellelyon/TikTok: @drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyon

    Timestamps

    00:00 - Introduction

    01:25 - Erections predict cardiac events

    01:41 - The pen and artery analogy

    03:40 - No health milestones for men

    07:52 - Normal structure and function

    11:45 - The five S's of men's health

    21:24 - Why "normal" testosterone misleads

    25:00 - Testosterone and fertility risk

    31:05 - Steroids versus FDA-approved agents

    41:13 - The untreated 25-year-old

    43:56 - Sperm health and home testing

    52:02 - Peyronie's disease and injury

    1:01:34 - Protein, nutrition, supplements

    1:05:09 - Daily Cialis as a pre-workout

    1:13:32 - The sponge analogy

    1:15:31 - Erectile fitness tracking

    1:23:05 - The penis pump, used right

    1:27:24 - Restoring lost size

    1:35:00 - Traction and girth enhancement

    1:46:00 - Women's anatomy and pleasure

    If you found this episode valuable, share it with someone who would benefit from it.

    Disclaimers: This episode includes paid sponsorships.

    The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

  • Most people think the cholesterol number on their lab report tells them whether their heart is at risk. But former National Lipid Association President Dr. Kevin Maki explains that LDL is just one piece of a much bigger picture and focusing on it alone can mean missing the markers that matter most.

    In this episode, Dr. Gabrielle Lyon sits down with Dr. Kevin Maki, former President of the National Lipid Association and co-editor-in-chief of the Journal of Clinical Lipidology, to discuss:

    Why ApoB and Lp(a) are better predictors of heart risk than LDL and why only about 2% of people ever get Lp(a) testedWhat a beef-vs-chicken feeding study revealed about red meat and cholesterol (the LDL results came back identical at 112 mg/dL)The evidence behind the seed oil debate, including why higher linoleic acid levels tracked with lower inflammation markers across a 2,000-person datasetWhy the balance of cholesterol-raising and cholesterol-lowering foods matters more than saturated fat aloneThe simple "ABCs" framework: A1c, blood pressure, cholesterol - for actually lowering long-term cardiovascular risk

    By the end, you'll know which numbers actually predict heart risk, which tests to ask your doctor for, and how to cut through the conflicting noise around fat so you can make evidence-based decisions for the long haul.

    Thank you to our sponsors:

    OneSkin - Get 15% off at https://bit.ly/4tZnOpk with code DRLYONBodyHealth - Use the code LYON20 to get 20% off your first order https://bit.ly/48SJ7AC Amp - Visit https://bit.ly/3RcmqBz to get your AI-powered at-home gym for smarter, personalized training.

    Explore More from Dr. Gabrielle Lyon

    Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/

    Find Dr. Kevin Maki at:

    Midwest Biomedical Research: https://www.mbclinicalresearch.com/ LinkedIn: / kevin-c-maki-phd-497ba34

    Connect with Dr. Gabrielle Lyon:

    Instagram: https://www.instagram.com/drgabriellelyon/TikTok: @drgabriellelyon X (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyon

    Chapters

    00:00 - Introduction

    00:31 - Dr. Kevin Maki and the National Lipid Association

    01:04 - New dietary guidelines and the LDL confusion

    02:04 - What raises and lowers LDL cholesterol

    03:51 - Cholesterol levels from birth through puberty

    05:11 - The lipid panel kids should get before age 11

    06:42 - Lp(a): the test only 2% of people get

    08:18 - ApoB and the three risky particle types

    11:35 - Do we have evidence for "lower is better"?

    14:09 - The FLASH-GLICK risk factor framework

    17:10 - The 10% saturated fat guideline explained

    19:36 - Many dietary patterns can be healthy

    24:50 - Beef vs. chicken: identical LDL results

    27:10 - The balance of fatty acids that matters

    29:24 - Olive oil vs. corn oil feeding study

    31:00 - Lower for longer: 40-year risk reduction

    34:15 - Genetic cholesterol disorders and risk

    40:33 - The omega-3 index and why it matters

    49:10 - Are seed oils really driving inflammation?

    53:11 - How seed oils are processed and refined

    1:07:48 - Inherited beliefs and outdated nutrition science

    1:08:54 - Butter vs. cheese and high-fat dairy surprises

    1:14:48 - Exercise effects on HDL and triglycerides

    1:21:20 - The ABCs of reducing cardiovascular risk

    If you found this episode valuable, share it with someone who would benefit from it.

    Disclaimers: This episode includes paid sponsorships.

    The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

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  • Colorectal cancer is now the leading cancer killer in adults under 50, and patients in their 20s are presenting with metastatic disease that has nothing to do with family history. Most physicians are still telling young patients with rectal bleeding that it's probably just hemorrhoids and that's costing lives.

    In this episode, Dr. Gabrielle Lyon sits down with Dr. Michelle Pearlman, a board-certified gastroenterologist and founder of a Miami-based gastro-metabolic clinic, to discuss:

    The specific warning signs every adult under 50 should never ignore, regardless of age including rectal bleeding, unintentional weight loss, and persistent abdominal painWhy GLP-1 medications like Ozempic and Zepbound are being miscategorized as weight loss drugs when they're actually metabolic reprogrammers with applications in fatty liver, sleep apnea, and inflammationThe protein, fiber, and resistance training protocol Dr. Pearlman uses to protect muscle mass in patients on GLP-1 therapyHow hormone replacement therapy combined with GLP-1s is changing body composition outcomes for perimenopausal women and why current guidelines are still 20 years behind the dataDr. Pearlman's personal osteoporosis diagnosis at 39, despite being a lifelong bodybuilder, and what it revealed about the diagnostic gaps in standard medicine

    This conversation gives you the framework to recognize the warning signs most physicians are still missing, and the foundational habits; nutrition, resistance training, and hormone optimization that protect your gut, bones, and muscle through midlife and beyond.

    Thank you to our sponsors:

    Cozy Earth - Go to https://bit.ly/4teXQhz for up to 20% off!

    Timeline - Get 20% off your Mitopure order at https://bit.ly/4eLBWhB

    Lucy - Get 20% off your next order with code DRLYON at https://bit.ly/42HiUlc, or find yours in store at https://bit.ly/3RfGnYa

    Amp - Visit https://bit.ly/3RcmqBz to get your AI-powered at-home gym for smarter, personalized training.

    Explore More from Dr. Gabrielle Lyon

    Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.com

    Weekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/

    Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/

    Find Dr. Michelle Pearlman at:Instagram: https://www.instagram.com/michellepearlmanmd/Website: https://www.primeinstitute.us/Connect with Dr. Gabrielle Lyon

    Instagram: https://www.instagram.com/drgabriellelyon/

    TikTok: https://www.tiktok.com/@drgabriellelyon

    X (Twitter): https://x.com/drgabriellelyon

    Facebook: https://www.facebook.com/doctorgabriellelyon

    Chapters

    00:00 - Introduction: Colorectal cancer under 50

    01:15 - The gastro-metabolic approach explained

    03:30 - Why nutrition isn't taught in GI fellowship

    05:45 - When the colonoscopy is normal but patients suffer

    07:00 - Weight, reflux, and visceral fat

    09:15 - PPIs, bone density, and long-term risk

    11:30 - Three things to never do for gut health

    14:00 - Ultra-processed food and early-onset cancer

    16:45 - Rectal bleeding, warning signs, and age

    19:00 - Screening guidelines and the obesity gap

    22:30 - GLP-1 medications: history and mechanism

    27:15 - Hunger, cravings, and food noise

    30:00 - The stigma around metabolic medications

    33:45 - Side effects: nausea, reflux, constipation

    38:30 - Compounded formulations and pharmacy safety

    42:00 - Hair loss, protein, and supplementation

    45:15 - Pill versus injection delivery systems

    49:30 - Fiber, the microbiome, and short-chain fatty acids

    54:00 - GLP-1s plus hormone replacement therapy

    58:45 - Testosterone, Kyzatrex, and women's bone health

    1:03:00 - Pearlman's osteoporosis diagnosis at 39

    1:09:30 - The diagnostic gap in standard medicine

    1:14:00 - Building Bite MD and the future of nutrition tech

    Disclaimers: This episode includes paid sponsorships.

    The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

  • Most parents are quietly paving the road their kids were supposed to learn to walk on by themselves and Jocko Willink has spent 20 years watching what happens when that road is too smooth.

    In this episode, Dr. Gabrielle Lyon sits down with Jocko Willink, retired Navy SEAL commander, founder of Echelon Front, and bestselling author of Extreme Ownership and Discipline Equals Freedom, to discuss:

    Why the "apex parent / apex kid" mindset is a quiet trap, and what to do instead of paving the roadHow nature vs nurture actually plays out and what you can and cannot shape in your childThe one trait Jocko wants his kids to inherit (and why every virtue becomes a vice when pushed to the extreme)The lie that successful, high-functioning people tell themselves about wanting moreThe single most important trait of a great leader and the one habit Jocko says will make every other part of your life better starting tomorrow

    You'll walk away with a clearer operating system for the kind of parent, leader, and person you actually want to be and the one habit Jocko swears is the highest-ROI move any human can make.

    Thank you to our sponsors:

    BodyHealth - Use the code LYON20 to get 20% off your first order https://bit.ly/48SJ7ACOur Place - Visit https://bit.ly/4c8OrAB and use code DRLYON for 10% off sitewide.Branch Basics - Get 15% off the Premium Starter Kit at https://bit.ly/4eu4Mm8 with the code DRLYON.Amp - Visit https://bit.ly/41BvjXj to get your AI-powered at-home gym for smarter, personalized training.

    Watch on Spotify. If you’re subscribed to Spotify Premium, you don’t get any Spotify ads on my video.

    Explore More from Dr. Gabrielle LyonPremium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/
    Find JOCKO WILLINK at:Instagram: https://www.instagram.com/jockowillink/?hl=enFacebook: https://www.facebook.com/jkowillink/Tiktok: https://www.tiktok.com/@jocko_willinkX: https://x.com/jockowillinkYouTube: https://www.youtube.com/@JockoPodcastOfficialLinkedin: https://www.linkedin.com/in/jocko-willink-260b289/Get Jocko Willink’s books: https://jocko.com/books/Connect with Dr. Gabrielle Lyon

    Instagram: https://www.instagram.com/drgabriellelyon/

    TikTok: @drgabriellelyon

    X (Twitter): https://x.com/drgabriellelyon

    Facebook: https://www.facebook.com/doctorgabriellelyon

    Chapters

    00:00 - Introduction: Leadership and parenting are the same skill

    03:24 - Nature vs nurture and the kids who won't compete

    06:56 - The guardrails of failure

    07:48 - Dharma and the path kids are meant to walk

    09:17 - The one trait Jocko wants his kids to inherit

    11:33 - What daughters should learn about men from their fathers

    13:32 - How men and women experience fear differently

    14:24 - Rebuilding trust after good people do bad things

    18:34 - Letting your daughter do cheerleading

    21:22 - Hiring people by putting them in the real environment

    24:22 - The lie successful people tell themselves

    29:16 - Strategic thinking vs the donut decision

    35:18 - What failure teaches that success cannot

    38:25 - Why Jocko stopped being about himself

    44:09 - Aging, losing movements, and rage against the dying of the light

    46:49 - Why a leader has to be in physical shape

    50:41 - The single most important trait of a leader

    54:09 - The one habit that changes everything

    If you found this episode valuable, share it with someone who would benefit from it.

    Disclaimers: This episode includes paid sponsorships.

    The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

  • Most men don't know they have a pelvic floor, and most doctors aren't trained to look for dysfunction in it. The result: testicles are being surgically removed for pain that's actually neuropathic, at double the rate of a far more effective nerve-sparing procedure.

    In this episode, Dr. Gabrielle Lyon sits down with Dr. Susan Macdonald, a board-certified urologist, surgical program director at Penn State, and one of only ~30 U.S. specialists treating chronic pelvic pain in men, to discuss:

    Why "prostatitis" is often the wrong diagnosis, and how rounds of antibiotics mask the real problemThe male pelvic floor anatomy almost no medical school teaches, and how to recognize dysfunction in yourself or a patientOff-label medications (Cymbalta, gabapentin, amitriptyline) that are quietly transforming chronic pelvic pain treatmentWhy erectile dysfunction is rising sharply in teenagers, and the role pornography plays in rewiring young brainsWho actually qualifies for a penile implant, and what the surgery really involves

    If you've been told your pain is "all in your head," or you're a clinician seeing patients fall through the cracks, this conversation gives you the framework, the language, and the next steps to find real answers.

    Thank you to our sponsors:

    Manukora - Go to https://www.MANUKORA.com/DRLYON to save 31% plus $25 worth of free gifts.Timeline - Get 20% off your Mitopure order at https://www.timeline.com/lyonBONCHARGE - Save 15% at https://boncharge.com/ with code DRLYON

    Explore More from Dr. Gabrielle Lyon

    Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/

    Find Dr. Susan Macdonald at:

    Instagram: https://www.instagram.com/drsusanmacdonald/

    X (Twitter): https://x.com/smacdonald_md

    LinkedIn: https://www.linkedin.com/in/susan-macdonald-506324191/

    Connect with Dr. Gabrielle Lyon

    Instagram: https://www.instagram.com/drgabriellelyon/

    TikTok: @drgabriellelyon

    X (Twitter): https://x.com/drgabriellelyon

    Facebook: https://www.facebook.com/doctorgabriellelyon

    Chapters

    00:00 - Introduction

    01:42 - Meet Dr. Susan Macdonald

    03:00 - The high-powered lawyer nobody could help

    05:01 - Why testicle pain is 5% of urology visits

    07:49 - Men have a pelvic floor (and what it does)

    12:46 - How a man knows he has pelvic floor dysfunction

    21:30 - Why these muscles are "too tight" in men

    26:33 - Chronic pain rewires the brain

    29:21 - Stress, trauma, and the mind-body connection

    33:29 - Stretching, breathing, and self-treatment at home

    36:21 - The medications that actually work (Cymbalta, gabapentin)

    44:34 - Muscle relaxers, acupuncture, and the guidelines panel

    55:09 - Sexual trauma and chronic pelvic pain

    01:00:08 - The "pain plus" diagnostic framework

    01:05:23 - The micro-surgical denervation surgery

    01:08:36 - Erectile dysfunction in 17-year-olds

    01:11:00 - How porn rewires young men's brains

    01:18:27 - 40% of men by 40, 50% by 50

    01:23:39 - Penile implants: who qualifies, how they work

    01:28:10 - Stage 4 cancer at 42 and the pivot to teaching

    01:34:17 - Living big with finite time

    01:39:00 - Closing message to chronic pain patients

    If you found this episode valuable, share it with someone who would benefit from it.

    This episode includes paid sponsorships.

    The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

  • Most people are chasing the wrong version of strength and paying for it with pain, poor movement, and a body that breaks down faster than it should. In this episode, Dr. Gabrielle Lyon sits down with Mark Bell, elite powerlifter, entrepreneur, and founder of Slingshot, to discuss:

    Why strength training is essential at every age but most people are defining "strength" too narrowlyHow modern life has created an "exercise deficiency," and why artificial exercise is the only fixThe truth about fat, protein, and the biggest nutrition mistakes holding people back from lasting weight lossThe emerging peptide and drug landscape, and what it means for the future of health optimizationWhy forcing your kids to move isn't cruelty, it's one of the most protective things you can do as a parent

    Whether you're 25 or 75, this episode will challenge how you think about movement, muscle, and what it actually means to be strong physically and mentally.

    Thank you to our sponsors:

    OneSkin - Get 15% off with code DRLYON — https://bit.ly/4tZnOpkAmp - Get your AI-powered at-home gym for smarter personalized training — https://bit.ly/41BvjXjBranch Basics - Get 15% off the Premium Starter Kit with the code DRLYON — https://bit.ly/4eu4Mm8BodyHealth - Get 20% off your first order with the code LYON 20 — https://bit.ly/4etWlr5

    Explore More from Dr. Gabrielle Lyon

    Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content — https://foreverstrong.supercast.comWeekly newsletter: Recipes, podcast updates, and practical weekly insights — https://drgabriellelyon.com/sign-up/Apply to become a patient: Personalized care with Dr. Lyon's clinical team — https://drgabriellelyon.com/new-patient-inquiry/

    Find Mark Bell at:

    https://www.instagram.com/marksmellybell/https://www.youtube.com/@MarkBellSuperTrainingSlingshot: https://originmaine.com/

    Connect with Dr. Gabrielle Lyon

    Instagram: https://www.instagram.com/drgabriellelyon/TikTok: @drgabriellelyonX (Twitter): https://x.com/drgabriellelyonFacebook: https://www.facebook.com/doctorgabriellelyon

    Chapters

    00:00 – Introduction

    02:48 – Mark Bell's Motto

    07:00 – Mind-Body Strength Connection

    10:45 – Wrestling > Powerlifting > Entrepreneurship Journey

    17:37 – Rationale of Goals

    22:04 – Effects of Consistency and Efficiency in Training

    32:55 – Recommended Training and Lifestyle Modalities

    37:32 – Artificial Exercise vs. Exercise Deficiency

    37:47 – "Artificial Exercise" and "Exercise Deficiency"

    39:36 – Impact of Physical Activity in Children

    44:57 – Biggest Mistake in Weight Loss

    50:46 – Overconsumption is a Problem

    53:17 – Era of GLP-1, Peptides, and Steroids

    1:02:28 – Training to Decrease Mortality

    1:03:33 – Cancer Research Updates

    1:04:36 – Collective Research on Supplementation

    1:16:50 – Influencing Children to Engage in Physical Activities

    Share This Episode If you found this episode valuable, share it with someone who would benefit from it.

    Disclaimers: This episode includes paid sponsorships.

    The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

  • We are living through one of the most significant shifts in medicine in generations, and most people don’t fully understand what it means. Dr. Christle Guevarra joins me to zoom out on the entire GLP-1 landscape; from the drug’s origins as a modest diabetes treatment in 2005 to today’s third-generation medications still moving through clinical trials, and what all of it means for the future of obesity, performance, and longevity.

    🙌Thank you to our sponsors:

    🌍 Cozy Earth - Go to https://bit.ly/4teXQhz for up to 20% off!

    🤍 Timeline - Get 20% off your Mitopure order at https://www.timeline.com/lyon

    🚲 Carol Bike - Visit https://bit.ly/4tg4cxa and use code LYON for $100 off your CAROL Bike

    Explore More from Dr. Gabrielle Lyon:

    Premium Podcast Subscription: Ad-free episodes, key takeaway summaries, exclusive Q&A, and behind-the-scenes content https://foreverstrong.supercast.com

    Weekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/

    Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient-inquiry/

    Connect with Dr. Christle Guevarra

    YouTube: https://bit.ly/4vDMVQa

    Instagram: https://bit.ly/4mxnfAc

    Get Dr. Christle Guevarra’s book, “Bodybuilding Anatomy”: https://bit.ly/3ODIDYd

    📺Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:

    YouTube: https://bit.ly/4boCFC3

    Spotify: https://bit.ly/4cWTbLG

    📱Connect with Dr. Gabrielle Lyon:

    Instagram: https://bit.ly/4uk9adc

    TikTok: https://bit.ly/3OFK3kJ

    X.com: https://bit.ly/4l3YlaX

    Facebook: https://bit.ly/3MBrJso

    ⏰Timestamps:

    00:00 Intro of Show

    06:48 Changes in the Fat Loss Landscape

    06:54 Engagement in Competitive Powerlifting

    11:29 Perspectives on GLP-1 Medication

    26:10 Perimenopause Journey

    27:13 Topamax

    28:03 Urosepsis

    30:23 Weight Loss Programming

    31:43 Patients' Decision to Take GLP-1

    37:44 Risks and Effects on Taking GLP-1

    38:10 Pancreatitis

    41:40 Fen-Phen (Fenfluramine/phentermine) / Ephedra

    45:59 Who Should Not Take GLP-1?

    49:24 Proper Nutrition to Support Taking GLP-1

    52:14 Recommendation for the New Dietary Guidelines

    59:01 Residency and Sports Medicine Fellowship

    1:02:38 Are Athletes Recommended to Take GLP-1?

    1:08:49 Lack of Randomized, Controlled Trials for Peptides

    1:10:38 Key Take-away's from Dr. Christle

    1:13:24 Should Women Weigh Themselves?

    1:21:02 Should Women Lift Weights?

    1:21:55 What's Next for Dr. Christle?

    ‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

    This episode includes paid sponsorships.

  • The moment you decide to show up publicly, you open the door to opinions from people who would never say those things to your face. Dominique Sachse, journalist, author, and content creator who has lived her life on camera for over three decades, gets honest about what it costs to put yourself out there, why online cruelty is a psychology problem more than a content problem, and how “Teflon Dom” developed the thick skin to let none of it redirect her.

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    Newsletter: https://bit.ly/402QCAj

    ⏰Timestamps:

    00:00 ​Intro of Show

    02:10 Dominique’s Mission

    05:13 Women’s Reinvention with Aging

    12:07 Handling People’s Opinions in the Media

    18:03 Why Dominique Wrote “Life Makeover”

    26:08 Activating One’s Faith through Life’s Challenges

    29:16 Decision to Leave the News Business

    34:12 Traditional Media Transitioning to Online Media

    37:09 How to Curate Information

    38:42 Effectively Communicating with Journalism and Research Skills

    43:17 Managing Conflicts On-and-Off Air

    45:28 The Aging Process

    49:53 Personal Training with Body Builders

    52:33 Changes in Training and Nutrition

    54:49 Importance of Discipline

    1:00:28 How Dominique Makes Decisions

    1:04:03 Dominique’s Goal and Message

    1:08:46 Midlife Wellness Protocols

    1:14:29 What’s Next for Dominique?

    ‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

    This episode includes paid sponsorships.

  • Only nine scientists were asked to advise on the 2025 Dietary Guidelines for Americans, and Dr. Tom Brenna was one of them. In this conversation, he pulls back the curtain on how dietary guidelines are actually made, why the process has never been the same twice, and what it was like to watch a decades-old saturated fat recommendation get carried forward despite a lack of evidence supporting it at the level of total mortality. This is the dietary guidelines conversation the internet has been missing: straight from someone who was actually in the room.

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    📱Connect with Dr. Tom Brenna

    Website: https://bit.ly/3O3cNUv

    Instagram: https://bit.ly/4s7UF9N

    LinkedIn: https://bit.ly/4shYfyl

    References:

    https://nutrition.org/american-society-for-nutrition-calls-for-strong-science-in-national-nutrition-guidance/

    https://ajcn.nutrition.org/article/S0002-9165(24)00527-6/fulltext

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    ⏰Timestamps:

    00:00 ​Intro of Show

    00:14 Dr. Tom Brenna’s Background

    05:19 Working with IBM

    08:46 Family Life

    10:38 2015 vs. 2025 Dietary Guidelines for Americans

    28:06 American Society for Nutrition: Behind-the-Scenes of Dietary Guidelines

    32:10 History of Saturated Fat

    42:17 Different Types of Fat

    45:23 How Are People Eating during World War II

    51:09 The Whole Milk for Healthy Kids Act of 2025

    53:58 What is Saturated Fat?

    57:57 Link between Saturated Fat and Cardiovascular Diseases

    1:05:53 Saturated Fat vs. Total Mortality

    1:13:13 Best Studies on Saturated Fat

    1:14:42 Reduction of Saturated Fat = Lowered LDL Cholesterol

    1:22:35 Pregnancy and Fish Consumption Myths

    1:37:55 Recommended Nutrition

    1:39:59 Different Types of Oil and Effects on Health

    1:42:04 Omega 3’s and 6’s Recommendation

    1:50:02 Omega 3 Fatty Acids and ADHD

    1:50:54 What’s Next: Precision Nutrition and Genetics

    ‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

    This episode includes paid sponsorships.

  • In a world flooded with conflicting health advice, how do you actually figure out what’s true? Dr. David Allison, one of the most rigorous scientific minds in obesity and nutrition research, shared the exact framework he uses to evaluate evidence, from peer-reviewed trials to podcast recommendations to AI-generated summaries. He explains the difference between trusting science as a process and trusting individual studies, why most nutrition epidemiology functions more like advertising than research, and how ordinary people can build a reliable filter for health claims without a PhD.

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    LinkedIn: https://bit.ly/3O6quC2

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    Newsletter: https://bit.ly/402QCAj

    ⏰Timestamps:

    00:00 ​Intro of Show

    03:55 Dr. David Allison’s Background

    09:50 Principles vs. Scientific Data

    14:48 What is Doubly-Labeled Water?

    16:42 Misconceptions on Diet

    21:08 Concept of Human Discomfort

    24:18 Childhood Obesity

    28:49 Research: What Really is the Purpose?

    31:14 Can We Trust Science?

    40:54 INSERT LINK: NEWSLETTER ON OBESITY AND ENERGETICS

    40:54 Obesity: Causes and Treatments

    50:29 Different Outcomes from Weight Loss Drugs

    57:21 Safety is a Social Judgment

    1:00:18 Making Decisions in a Noisy Landscape

    1:08:29 Podcasts as a Good Source of Information

    1:16:09 Stance on Ultra-Processed Foods and Seed Oils

    1:22:50 Dr. David’s New Projects

    1:29:40 How to Make Good Decisions

    ‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

    This episode includes paid sponsorships.

  • Up to 70% of dementia may be preventable, so why aren’t more people talking about what actually drives cognitive decline? In this episode, I’m with Dr. Tommy Wood, neuroscientist and author of “The Stimulated Mind,” to explore the lifestyle levers that protect your brain across a lifetime. Learn how white matter hyperintensities develop and whether they can reverse, what MCTs and ketones actually do for a glucose-starved brain, and why social connection may be the most underrated variable in cognitive aging. What is the one change you could make today that would most protect your brain tomorrow?

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    Get Dr. Tommy Wood’s book, “The Stimulated Mind”: https://bit.ly/4bYIUxE

    Listen to "Better Brain Fitness" on all your favorite platforms!

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    📱Connect with Dr. Tommy Wood:

    Website: https://bit.ly/3NIV4RX

    YouTube: https://bit.ly/3NVWWHa

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    LinkedIn: https://bit.ly/4c0iETw

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    📺Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:

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    Newsletter: https://bit.ly/402QCAj

    ⏰Timestamps:

    00:00 ​Intro of Show

    01:52 Elite Athlete’s Brain and Emotional Regulation

    06:51 How to Regulate Emotions

    11:30 Mindset Impacting Hormonal Responses

    15:39 Future-Proofing the Brain

    19:42 Brain Development vs. Shrinkage

    26:11 Dementia Types, Causes, and Prevention

    39:29 Social Isolation Influencing Cognitive Function

    50:00 Social Stress’ Drivers

    52:34 Non-Negotiable’s to Avoid Dementia Risks

    57:42 Seafood Consumption Beneficial for Brain Function

    1:03:35 Alcohol and Sleep Impacting the Brain

    1:10:16 Is Brain Function Recovery Possible?

    1:18:43 Use of Ketones and Glucose for Cognitive Recovery

    1:23:09 Power of Mindfulness

    1:27:06 Get Dr. Wood’s Book

    ‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

    This episode includes paid sponsorships.

  • Metabolic flexibility is your body’s ability to efficiently burn fat or carbohydrate depending on demand, may be one of the most important and least understood markers of long-term health. In this episode, I’m with Dr. Martin Gibala to explore the emerging science of Fat Max, why mitochondrial quality is central to both performance and longevity, and how sprint interval training produces comparable mitochondrial adaptations to traditional endurance work in a fraction of the time. Could the key to better metabolic health be less about the hours you log and more about how hard you’re willing to push?

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    Get Dr. Martin Gibala’s book, “The One-Minute Workout” here: https://bit.ly/4lxBchq

    Connect with Dr. Martin Gibala

    Website: https://bit.ly/3P8ROjd

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    ⏰Timestamps:

    00:00 Intro of Show

    01:26 What is High-Intensity Interval Training?

    05:04 HIIT to Improve Health Fundamentally

    08:23 Exercise Ratio for General Individuals vs. Athletes

    14:29 Dr. Lyon's Workout Routine

    16:47 High-Intensity Interval vs. Sprint Interval Training

    20:23 New Studies on Sprint Interval Training

    24:57 The One-Minute Workout

    26:57 CAROL Bike Mechanics

    28:59 Benefits of High-Intensity Interval Training

    37:21 Fuel Utilization: Sprint Interval vs. Slow, Steady-State Training

    45:38 Metabolic Flexibility Definition

    46:41 Fat Max Definition and Evaluation

    50:26 Zone Training Model

    58:00 Designing the Health of the Nation

    1:04:04 How to Improve Body Composition

    1:11:40 REHIT: Reduced Exertion, High-Intensity Training

    1:21:59 Does HIIT Prevent Sarcopenia?

    1:27:27 VO2 Max: Factoring Age and Sex

    1:34:28 Designing the Ideal Workout Week

    1:39:14 Importance of Rest Intervals

    1:45:14 Connect with Martin

    ‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

    This episode includes paid sponsorships.

  • The most decorated woman in motorsports history will tell you she feared losing far more than she loved winning, and that fear is exactly what drove her to the top. In this episode, I’m with racing legend Danica Patrick to unpack the psychology of elite performance, from the “blind faith” that carried her through two decades of racing to the nervous system conditioning she built starting at age 10. What would be possible for you if you learned to channel pressure instead of escaping it?

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    Listen to “Pretty Intense Podcast” on all your favorite platforms!

    YouTube: https://bit.ly/4cyZPrt

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    Get Danica Patrick’s book, “Pretty Intense” here: https://bit.ly/4rXdH3r

    📱Connect with Danica Patrick

    Website: https://bit.ly/4lfA9SQ

    YouTube: https://bit.ly/3OVYeCk

    Instagram: https://bit.ly/4bht0Ni

    TikTok: https://bit.ly/4sCyDNf

    Facebook: https://bit.ly/3Nuajhw

    X.com: https://bit.ly/3Pdog3X

    LinkedIn: https://bit.ly/4cWK6mn

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    📺Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:

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    Newsletter: https://bit.ly/402QCAj

    ⏰Timestamps:

    00:00 Intro of Show

    02:05 Understanding the Idea of Pressure and Challenge as a Kid

    05:00 Managing Wins and Losses

    09:45 Automaticity to Fear

    11:44 Managing Nervous System under High Pressure

    17:34 Danica's Pre-Performance Rituals

    20:21 Performance Becoming One's Identity

    21:23 Danica Working with Dr. Lyon

    26:24 Discipline for Proper Recovery

    28:47 Tips for Someone Going through the Same Issues

    31:01 Working with Different Doctors

    34:01 Women's Intuition in Hiring

    37:14 Women in Male-Dominated Industries

    41:42 There Are No Shortcuts to Success

    43:01 Performing in High-Pressure Situations

    45:51 Importance of Having Alone Time

    48:34 What is Home Energy?

    51:20 Flow of State: Passion and Creativity

    55:51 Medicine in the AI Era

    59:32 Rapid Fire Q&A

    ‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

    This episode includes paid sponsorships.

  • I’m joined by Dr. Heather Hirsch to debunk the persistent myths surrounding hormone replacement therapy and explain why the 2002 Women’s Health Initiative data was so widely misinterpreted. We discuss how optimized estrogen, progesterone, and testosterone levels can protect your heart, bones, and brain health, helping you move past "normalized suffering" and into a proactive state of longevity. Whether you are in perimenopause or well past the ten-year window, you'll learn how to navigate personalized dosing and clinical data to reclaim your vitality and extend your health span.

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    Listen to “Women’s Health by Heather Hirsch, MD” on all your favorite platforms!

    Apple Podcasts: https://bit.ly/4l86Mlw

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    Get Dr. Heather Hirsch’s book, “The Perimenopause Survival Guide” here:

    https://bit.ly/4r2yXUd

    📱Connect with Dr. Heather Hirsch:

    Website: https://bit.ly/4smy4qJ

    YouTube: https://bit.ly/3NdevSH

    Instagram: https://bit.ly/4sfj11P

    TikTok: https://bit.ly/46v6Y8s

    Facebook: https://bit.ly/3OLI4LA

    X.com: https://bit.ly/3MY4Cbm

    LinkedIn: https://bit.ly/4u6rjeb

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    Newsletter: https://bit.ly/402QCAj

    ⏰Timestamps:

    0:00 Intro of Show

    6:00 Hormone Replacement Therapy: Where Are We Now?

    11:25 What is Menopausal Hormone Therapy?

    13:39 How Safe is Hormone Replacement Therapy?

    18:39 Access on the Studies on HRT

    23:10 Risks of Hormone Replacement Therapy

    27:24 Estrogen Does Not Cause Breast Cancer

    31:19 Estrogen and Accelerated Bone Loss

    34:51 Preventative Benefits of Estrogen

    38:47 Lifespan vs. Health Span

    39:22 When to Start Hormone Replacement Therapy?

    45:15 Blood Markers

    47:26 Progesterone: Effects, Timing, Dosage

    52:38 Testosterone: Effects, FDA Approval, Benefits, Risks

    1:00:44 Analysing the Numbers

    1:04:13 Link of HRT and Cognitive Function

    1:09:28 What Are Women Doing Wrong?

    ‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

    This episode includes paid sponsorships.

  • Male fertility is declining, and most men have no idea why.

    In this episode of The Dr. Gabrielle Lyon Show, Dr. Gabrielle Lyon sits down with Dr. Michael Eisenberg, Director of Male Reproductive Health at Stanford University and Chief Medical Advisor of SwimClub, to break down what truly determines sperm health and reproductive success.

    They discuss:

    How metformin, GLP-1 medications, testosterone therapy, and anabolic steroids affect male fertilityWhy sperm count is a powerful biomarker for long-term health and longevityThe role of sleep, muscle mass, exercise, diet, marijuana, and environmental toxins like microplasticsWhether platelet-rich plasma, or PRP, can help severe male infertilityDaily habits that quietly reduce a couple’s chances of conceiving

    If you care about fertility, hormones, metabolic health, or the future of men’s health, this conversation is essential.

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    BodyHealth - Get 20% off your first order with code LYON20 https://www.bodyhealthaffiliates.com/73L4QL3/7XDN2/Carol Bike - Visit https://carolbike.com/ and use code LYON for $100 off your CAROL BikeOneSkin - Get 15% off at https://www.oneskin.co/ with code DRLYON

    Find Dr. Michael Eisenberg at:

    Eisenberg Lab: https://med.stanford.edu/eisenberglab.htmlLinkedIn: https://www.linkedin.com/in/michael-eisenberg-9230a429X: https://x.com/DrMEisenberg

    Find Dr. Gabrielle Lyon at:

    Instagram:@drgabriellelyonTikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.pageOrder my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623

    Chapters:

    00:00 Sex habits, libido, GLP-1s, and what counts as male infertility

    01:46 Metformin and male fertility, what the Denmark study found

    07:27 How long sperm take to regenerate after meds, illness, or chemo

    09:24 GLP-1 medications, weight loss, and semen quality in men

    10:52 Testosterone therapy, anabolic steroids, and why sperm shuts down

    16:41 Sperm as a vital sign, fertility as a window into long term health

    19:14 Microplastics and environmental toxins found in semen

    22:21 Paternal age and sperm quality, DNA fragmentation and pregnancy risk

    26:03 Supplements and nutrients for sperm quality, what matters and why

    30:00 Sex frequency, masturbation, libido, and fertility myths

    35:38 Male infertility guidelines and medications that quietly lower fertility

    48:41 Semen quality and future disease risk, diabetes, cancer, mortality

    54:45 Anabolic agents, sperm banking, and how long frozen sperm lasts

    1:04:14 PRP for severe male infertility, azospermia and real outcomes

    1:16:41 New frontiers in male fertility, immune profiles, genomics, omics

    Disclaimers: This episode includes paid sponsorships.

    The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

  • Want ad-free episodes? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.com

    Self-doubt holds more people back than lack of skill or intelligence.

    In this episode, Dr. Gabrielle Lyon sits down with Dr. Shadé Zahrai to explore the science of confidence, self-trust, and peak performance. They break down why confidence comes after action, how self-image shapes success, and the four psychological drivers that determine whether you thrive or stay stuck.

    You will learn how body language influences perception, why high performers plan for failure, how perfectionism leads to burnout, and the subtle communication habits that undermine credibility. Most importantly, you will discover how to build what Dr. Zahrai calls Big Trust so you can back yourself before you feel ready.

    If you struggle with overthinking, imposter thoughts, or feeling capable but not fully confident, this conversation will give you practical tools to change how you show up.

    CHAPTERS

    00:00 Confidence science: feeling vs appearing

    00:51 The opposite of self-doubt and why confidence comes after action

    01:53 Self-trust before confidence

    03:03 Nonverbal confidence cues: posture, eye contact, smile, pace

    07:30 Body language feedback loop: posture and recall

    09:26 Shadé’s PhD on self-doubt under pressure

    12:22 What makes people successful: self-image

    12:30 Self-image blueprint and why change does not stick

    14:29 The Four A’s: Acceptance, Agency, Autonomy, Adaptability

    20:26 The self-awareness gap and changing personality traits

    22:30 Expectation bias and the scar experiment

    25:54 Self-doubt types: signal vs verdict

    28:30 Visibility, influence, and the people around you

    31:16 Which traits are easiest to change

    35:56 Why capable people still stay stuck

    40:25 Michael Phelps and visualizing failure recovery

    42:30 Stop rumination: stimulus control for worry

    47:45 Self-improvement vs perfectionism vs burnout

    56:53 The 4 inner deceivers: Judge, Protector, Neglecter, Ringmaster

    1:11:22 Peak performance and Big Trust

    1:19:19 Communication habits that kill credibility

    1:24:18 Stop over-apologizing and reframe emotion

    1:29:47 Daily habits to build Big Trust and audit your circle

    Thank you to our sponsors:

    Timeline - Get 35% off a Mitopure subscription at https://www.timeline.com/drlyonBodyHealth - Get 20% off your first order with code LYON20 https://www.bodyhealthaffiliates.com/73L4QL3/7XDN2/Four Sigmatic - Go to http://foursigmatic.com/gabrielle for a free bag of their dark roast ground coffee with a subscription (just pay for shipping & handling).

    Find Dr. Dr. Shadé Zahrai at:

    IG: https://www.instagram.com/shadezahrai/YouTube: https://www.youtube.com/shadezahraiBig Trust by Dr. Shadé Zahrai gives you the tools to quiet self-doubt and step forward with clarity, agency, and confidence. Get your copy here: https://www.amazon.ca/Big-Trust-Self-Doubt-Confidence-Success/dp/0063378159

    Find Dr. Gabrielle Lyon at:

    Instagram: @drgabriellelyonTikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623

    Disclaimers: This episode includes paid sponsorships.

    The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

  • Want ad-free episodes? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.com

    This episode brings together standout moments from The Forever Strong Experience, packed into one powerful episode.

    Featuring highlights from:

    Dr. Mark Hyman – Founder of the Cleveland Clinic Center for Functional Medicine, co-founder and CMO of Function Health, director of The UltraWellness Center, host of The Dr. Hyman Show (300M+ downloads), and 15x New York Times bestselling author, including Young Forever and Food Fix Uncensored.Layne Norton, PhD – Nutritional scientist, 4x USA Powerlifting National Champion and 2024 IPF M1 World Champion (93kg), record-setting deadlifter, coach to 1,700+ clients, and founder of Outwork Nutrition.Michelle Shapiro, RD – Integrative/functional dietitian who helps clients reverse anxiety, heal complex gut and immune issues, and approach weight with compassion. Host of the Quiet the Diet podcast.Alan Aragon, MS – Veteran nutrition researcher, co-author of 30+ peer-reviewed papers (including JISSN’s most-viewed article), ISSN Position Stand lead author, and founder of Alan Aragon’s Research Review and the Fit Advancement Mentorship (FAM).

    In this mashup, they break down:

    How to eat for long-term metabolic and muscle healthWhy protein and resistance training are non-negotiables as you ageThe role of stress, mindset, and past experiences in how you eat and feelWhat it really means to be “forever strong” in body and mind

    Perfect if you’re tired of conflicting nutrition advice and want clear, evidence-based guidance you can actually use.

    Thank you to our sponsors:

    Our Place - Visit https://www.fromourplace.com/DRLYON and use code DRLYON for 10% off sitewide.

    Four Sigmatic - Go to http://foursigmatic.com/gabrielle for a free bag of their dark roast ground coffee (just pay for shipping & handling).

    Cozy Earth - Go to https://www.cozyearth.com/DRLYON for up to 20% off!

    Chapters:

    00:00:00 The truth about nutrition

    00:01:06 Why is it so hard to follow health advice?

    00:03:07 What actually holds people back from progress?

    00:05:26 When “clean eating” backfires

    00:05:57 The nutrition “rule” that does more harm than good

    00:06:37 Why medicine got obsessed with BMI and fat

    00:08:47 Body composition fundamentals: what to do first

    00:10:53 “Rules” for better body composition (practical guidelines)

    00:13:20 Do you have to lift heavy to build muscle?

    00:16:24 Strength vs hypertrophy: what matters most as you age

    00:17:46 Sponsor: Our Place + What if muscle were taught as an organ system?

    00:20:14 Is obesity actually the root cause?

    00:21:24 Midlife: why “nothing’s working” (what’s really happening)

    00:23:21 Is it metabolic change or lifestyle, sleep, and stress?

    00:28:40 The most impactful shift for a muscle-centric nutrition plan

    00:30:44 Food anxiety: can you scare yourself into being fit?

    00:32:41 Digestion and absorption: making a muscle-centric lifestyle work

    00:33:42 The truth about nutrition: eat real food, food is medicine, personalize

    00:36:23 Sponsor: Four Sigmatic + Biggest myths in training and nutrition

    00:44:06 One thing to stop doing immediately

    00:45:31 Stress and the nervous system: how it affects digestion

    00:46:29 Practical tips for staying consistent under high stress

    00:48:09 The danger of sarcopenia (where we’re headed)

    00:50:14 Midlife expectations: slower progress, better strategy

    00:53:52 The long-term impact of eliminating food groups

    00:55:04 Healing vs cutting foods: what to do instead

    00:57:15 Sponsor: Cozy Earth + The myth you wish would die

    01:01:21 Travel: how to create “safety” and stay fed

    01:02:37 The airport backup plan (the “oh no” foods list)

    01:04:49 Expected challenges: planning so you don’t act surprised

    01:06:03 Boundaries and resistance training: what’s the standard?

    01:07:43 Mindset, trauma, and wellness (ACE questionnaire)

    01:13:13 Final question: What does “Forever Strong” mean to you?

    Find Dr. Mark Hyman: https://www.instagram.com/drmarkhyman/

    Find Layne Norton: https://www.instagram.com/biolayne/

    Find Michelle Shapiro: https://www.instagram.com/michelleshapirord/

    Find Alan Aragon https://www.instagram.com/thealanaragon/

    Find Dr. Gabrielle Lyon at:

    Instagram: @drgabriellelyonTikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Order The Forever Strong PLAYBOOK - https://drgabriellelyon.com/playbook/
  • Want ad-free episodes? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.com

    In this episode, Dr. Gabrielle Lyon sits down with Dr. Donald Layman, one of the world’s leading protein researchers and a key contributor to the newly released U.S. Dietary Guidelines. They explore why the old food pyramid failed, how nutrition science became driven by ideology instead of evidence, and what the updated guidelines finally get right about protein, fats, and carbohydrates. Dr. Layman explains why the long-standing protein recommendation of 0.8 g/kg was never intended for optimal health and how higher protein intake supports body composition, metabolic health, and nutrient adequacy.

    The conversation also dives into controversial topics including saturated fat, carbohydrate tolerance, animal versus plant protein, and the limitations of epidemiology in nutrition research. Gabrielle and Dr. Layman discuss how dietary guidelines shape school lunches, hospitals, and public institutions, and why a protein-first framework empowers individuals to make better nutrition decisions, especially as we age. This episode offers a clear, science-backed roadmap for understanding modern nutrition — cutting through misinformation and outdated dogma to focus on strength, longevity, and real-world application.

    Thank you to our sponsors:

    Timeline - Get 35% off a Mitopure subscription at https://www.timeline.com/drlyon

    Bon Charge - Save 15% at https://boncharge.com/ with code DRLYON

    Manukora - Go to https://www.MANUKORA.com/DRLYON to save 31% plus $25 worth of free gifts.

    Chapters:

    00:00 Why Dietary Guidelines Exist and Why This Moment Matters

    01:20 The Hidden Origins of the Food Pyramid (World War II + Public Health)

    02:55 The Original Protein RDA: A Basement Number, Not Optimal Health

    05:50 Why the Old Guidelines Focused on What Not to Eat

    07:25 Why Protein Was Avoided for Decades

    08:50 Nitrogen Balance: Why It Never Predicted Health Outcomes

    11:10 Epidemiology vs Controlled Trials in Nutrition Science

    13:05 How the Protein Evidence Was Evaluated for the New Guidelines

    14:15 Why Higher Protein Improves Weight, Fat Loss, and Lean Mass

    15:35 Is “Too Much Protein” Actually Dangerous?

    16:40 Nutrient Deficiencies Risk on Low-Protein Diets

    17:35 Animal vs Plant Protein: Bioavailability and Amino Acids

    18:45 Why 0.8 g/kg Was Never Better Than Higher Protein

    20:15 Empowering Consumers Instead of One-Size-Fits-All Nutrition

    21:10 How Guidelines Shape School Lunches, Hospitals, and the Military

    23:05 Protein-First Meal Planning Explained

    24:50 Why the First Meal Matters More as You Age

    27:15 Does Protein Distribution Matter After 50?

    30:00 Protein, Satiety, and Appetite Control

    31:05 Why “Ounce Equivalents” Between Plant and Animal Protein Don’t Work

    34:05 The Saturated Fat Myth and Why the 10% Rule Persists

    38:30 Where Saturated Fat Really Comes From in the Modern Diet

    39:45 Updated Fruit, Vegetable, and Grain Recommendations

    40:45 Carbohydrate Tolerance and Energy Needs

    42:45 Why RDAs, DRIs, and Guidelines Create Confusion

    44:20 Politics, Institutions, and Resistance to Change

    46:10 Why These Guidelines Are Different This Time

    47:25 Science Over Ideology: What the Report Gets Right

    48:35 Where to Find the Full Guidelines and Supporting Evidence

    50:50 Final Takeaway: Protein as the Organizing Principle of Nutrition

    Find Dr. Layman on X: https://x.com/donlayman

    Find Dr. Gabrielle Lyon at:

    Instagram: @drgabriellelyon TikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Order The Forever Strong PLAYBOOK - https://drgabriellelyon.com/playbook/

    Disclaimers: This episode includes paid sponsorships.

    The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

  • Order The Forever Strong PLAYBOOK: https://drgabriellelyon.com/playbook/

    Want ad-free episodes? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.com

    In this solo episode, Dr. Gabrielle Lyon shares the deeper mission behind The Forever Strong PLAYBOOK and the philosophy that has guided her work for decades.

    This conversation is not about trends, quick fixes, or aesthetics. It is about building strength as a lifelong responsibility and understanding why skeletal muscle is the foundation of health, resilience, and independence across the lifespan.

    Dr. Lyon introduces the Forever Strong ethos and walks through the four foundational pillars that support a strong life: how to think, how to eat, how to move, and how to recover. She explains why information alone does not change behavior and why clarity, discernment, and disciplined action are the true drivers of lasting health.

    Throughout the episode, Dr. Lyon challenges conventional narratives around aging, nutrition, exercise, and recovery. She reframes longevity through the lens of muscle span, the length of time a person lives with healthy, functional skeletal muscle, and explains how physical strength supports metabolic health, emotional regulation, and cognitive resilience.

    This episode is an invitation to step out of confusion and into a clear framework for living with intention. Strength is not something we inherit. It is something we build, choice by choice, day by day.

    Thank you to our sponsors:

    Timeline - Get 35% off a Mitopure subscription at https://www.timeline.com/drlyonFour Sigmatic - Go to http://foursigmatic.com/gabrielle for a free bag of their dark roast ground coffee (just pay for shipping & handling).

    Find Dr. Gabrielle Lyon at:

    Instagram:@drgabriellelyonTikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyon

    Timestamps:

    00:00 – The Forever Strong Mission

    01:15 – The Forever Strong Ethos

    06:00 – Muscle as the Organ of Longevity

    09:40 – How to Think

    10:24 – Using the Body to Train the Mind

    19:41 – Discernment and Mental Strength

    28:43 – How to Eat

    38:10 – Protein, Carbohydrates, and Metabolic Health

    48:04 – Food Quality and Nutrient Density

    51:30 – How to Move

    57:59 – Training for Strength and Sustainability

    1:06:39 – How to Recover

    1:12:00 – Forever Strong

    Disclaimers: This episode includes paid sponsorships.

    The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

  • Pre-order The Forever Strong PLAYBOOK today to unlock over $400 in free bonuses and learn how to build the muscle, resilience, and metabolic health that actually determine how well you age. https://drgabriellelyon.com/playbook/

    Want ad-free episodes? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.com

    In this episode, Gabrielle Lyon sits down with Leila Hormozi to discuss the journey from grit to empathy in both personal and professional life. Leila shares candid stories of building her first business, the sacrifices involved, and how her experiences in fitness shaped her entrepreneurial mindset. The conversation explores the value of failure, the importance of discipline, and what it truly takes to achieve business success, reflecting on the unique challenges and rewards that women encounter in leadership roles.

    Gabrielle and Leila also open up about balancing ambition, relationships, and personal well-being. They address how to build trust, practice self-belief, and handle the pressures of being public figures with authenticity. You will find practical insights on navigating discomfort, the importance of continuous growth, and on creating a fulfilling life based on clear priorities and honest reflection. The episode is filled with relatable stories and actionable advice for anyone focused on self-development and leadership.

    Chapters:

    0:00 – From Grit to Empathy: How Leila’s Perspective Shifted

    1:33 – Why Fitness Built the Foundation for Business Success

    3:38 – Confidence, Self-Belief, and the Difference Between Rookie and Seasoned Entrepreneurs

    8:23 – Discomfort, Anxiety, and Paying the Price for Growth

    12:58 – Becoming Public-Facing and Outgrowing the Persona You Created

    16:01 – Creating Content Without a Funnel or Ego-Driven Motives

    19:32 – Why Fewer Women Teach Business at Scale

    22:42 – What Actually Makes a Business Legitimate

    24:23 – Trust, Relationships, and Learning to Trust Yourself

    26:38 – Success vs Happiness and the Tradeoffs People Ignore

    31:56 – Sacrifice by Season: Constraints, Focus, and Capacity

    35:14 – Personal Trade-Offs and the Real Cost of Success

    36:50 – Growth Levels Are About Exposure, Not Time

    37:25 – Why You Should Stress Yourself Out More (Short-Term)

    43:04 – Social Media, Authenticity, and Being Fully Human

    46:15 – Reading Psychology and Understanding Culture

    48:19 – Maintaining Relationships Between High Achievers

    54:19 – Renegotiating Relationship Roles as Life Evolves

    59:54 – Belief Is an Output, Not an Input

    1:04:07 – Changing Your Relationship With Discomfort

    1:04:55 – What’s Next: Expansion, Health, and Long-Term Vision

    Thank you to our sponsors:

    OneSkin - Get 15% off at https://www.oneskin.co/ with code DRLYONBodyHealth - Get 20% off your first order with code LYON20 https://www.bodyhealthaffiliates.com/73L4QL3/7XDN2/Bon Charge - Save 15% at https://boncharge.com/ with code DRLYON

    Find Leila Hormozi at:

    IG: https://www.instagram.com/leilahormozi/YouTube: https://www.youtube.com/@leilahormozi

    Find Dr. Gabrielle Lyon at:

    Instagram: @drgabriellelyonTikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonApply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/Pre-order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623

    Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

    This episode includes paid sponsorships.