Episodios

  • Mitrix Bio

    Website:
    https://www.mitrix.bio/

    Contact form on Website

    Show notes:


    Personal introduction:

    Bioreactor-grown mitochondria

    8-9 years old field

    Grow young healthy mitochondrial and transplant them into the cells




    Had a few software companies on the 1990’s and fusion start-ups

    Stanford accelerator


    Lasers

    Molecular and biological imaging

    Mito-field is booming

    The mechanisms of the mitochondria than the biologics of them

    Gas turbines Little rotating turbines

    Combust fuel and oxygen

    That does anything to power the cell



    The main question:
    What is aging?

    Aging is healing, and the loss of the ability to heal

    The body and cells are not static

    There is enough rebuilding capacity when you are young

    As you age, the energy available to rebuild your cells slacks off

    They can’t replicate as fast

    Your body can’t afford to maintain large muscles so they shrink

    “We have made older animals younger…”

    They just need the higher levels of energy that is lost after youth



    The theory: texting and repairing mechanisms weaken and don’t have enough energy to do their jobs as effectively

    The brain and heart don’t decline as fast as the rest of the body

    The kidneys and skin and muscles decline the fastest

    Mitochondria are fundamental to all of your cells and organs and muscles

    10% of you body weight and generate 90% of your energy in your body

    Merged a billion years ago with simple-celled organisms




    Mitochondrial dna


    You start with One nuclear dna and 500,000 mtDNA

    26 major groups of mtDNA


    As you age the dna acquires copying errors like a computer disk that needs to be cleaned up

    Mitochondrial energy decline IS aging

    Hallmarks of aging : Both nuclear dna and mtDNA are decaying and declining

    You have to replace a car battery, and we should be able to do the same thing with ourselves: the body and car can just keep going….

    The cells will scoop up the new mitochondria and use the new fresh free mitochondria

    75 years old, you can feel 40-45 years old again

    Skin will get tighter and muscles will regrow




    Reversing aging and not just slowing it down

    Starting with the longevity market / field

    Most of it is fluff and noise and bubbles that pop

    We have a bubble because there’s a huge opportunity and a lot of people dive in

    A lot of billionaires investing

    Altos Laboratories from Jeff Bezos, Amazon

    Retro.bio by Sam Altman /Open Ai, ChatGPT

    New Limit from Brian Armstrong, coinbase

    Hevolution Project by Saudi Arabia





    One or two good approaches:

    Mitochondria transplants

    Epigentic reprogramming. Future biogenetic mitochondria producing machines in every house as a daily treatment/supplement

    Holy Fire book

    Correlation vs causation

    Secondary and tertiary effects

    Mitochondria is a primary cause of aging

    Telomere is secondary or just correlary effect

    “Allow aging to happen” as a compromise that’s a trade off

    Famine and intermittent fasting vs caloric restriction

    The body uses the muscles to funnel to the heart and brain

    Intermittent feasting

    Saunas are recommended

    There are a lot of excesses in the longevity field

    Lots of vitamins

    Lots of running

    More is not always better

    Minimum effective dose

    Maximum effective dose

    Homeostasis





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