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    G’day G’day G’day! Or should we say Ho! Ho! Ho!

    Welcome to The Oncology Journal Club Podcast’s Christmas Special!

    Where we take our fun and educational oncology learning resource for medical professionals to new festive heights.

    Produced by Rachael Babin, from The Oncology Podcast. Joined by our esteemed hosts: Professor Craig Underhill, Dr. Kate Clarke, and Professor Christopher Jackson.

    Join us as we reflect on the year's most impactful studies and developments of 2024. You'll discover the best papers of the year, the worst papers and of course, our favourite ‘blow your own trumpet' paper. You’ll also find out which host’s most listened to track of the year was by Beyonce.

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    This episode is dedicated to the memory of Russell Conley. Join us as we honour Russell's extraordinary contributions, whose legacy in GI cancer research will continue to resonate for years to come.

    For papers, bios and other links visit the Show Notes on our website.

    For the latest oncology news visit www.oncologynews.com.au.

    We invite healthcare professionals to join The Oncology Network for free - you'll also receive our free weekly publication The Oncology Newsletter.

    The Oncology Podcast - An Australian Oncology Perspective

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    What if we told you that cancer care could be kinder to both the planet and the patient? Join us for another enlightening and educational conversation with Professor Craig Underhill, Dr. Kate Clarke and Professor Christopher Jackson.

    Laugh along with Craig who, despite battling 'man flu,' sheds light on reducing the climate toxicity of cancer care. Meanwhile, Kate reassures listeners by debunking myths about the safety of oestrogens in hormone replacement therapy and IVF in patients with breast cancer, shifting focus to the real culprit—progesterone. CJ guides you through the intricacies of cross-trial comparisons in advanced melanoma, breaking down Professor Georgina Long's study on nivolumab-based therapies with a focus on the utility of propensity scores.

    We also spotlight initiatives aimed at improving cancer outcomes for First Nations communities in Australia, such as the introduction of cancer navigators.

    Dive into the latest episode of The Oncology Journal Club Podcast for a blend of humour, hope and hard-hitting discussions that promise to challenge and inspire.

    For papers, bios and other links visit the Show Notes on our website.

    For the latest oncology news visit www.oncologynews.com.au.

    We invite healthcare professionals to join The Oncology Network for free - you'll also receive our free weekly publication The Oncology Newsletter.

    The Oncology Podcast - An Australian Oncology Perspective

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    As we head toward the end of the year, the Oncology Journal Club Podcast team reflect on learnings from the last big international conference of the year.

    With 15 papers across various specialties, we've got you covered with an insightful exploration of all the pivotal studies. You can expect expert analysis alongside our unique blend of humour, banter and bad dad jokes.

    With our incredible Hosts - Professor Craig Underhill, Dr Kate Clarke and Professor Christopher Jackson.

    For papers, bios and other links visit the Show Notes on our website.

    For the latest oncology news visit www.oncologynews.com.au.

    We invite healthcare professionals to join The Oncology Network for free - you'll also receive our free weekly publication The Oncology Newsletter.

    The Oncology Podcast - An Australian Oncology Perspective

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    Welcome to Episode 28 of The Oncology Podcast's Experts On Point series, brought to you by The Oncology Network. Hosted by Rachael Babin.

    Are you talking to your patients about sex enough? Research suggests that most healthcare professionals aren’t having these conversations as often as patients would like.

    Sexual health should be a core component of holistic patient care.

    To shed light on this critical topic, Rachael is joined by Associate Professor Safeera Hussainy, Senior Pharmacy Research Manager at the Peter MacCallum Cancer Centre in Melbourne, Australia.

    From lifestyle changes and psychosocial interventions to hormone replacement therapies, lubricants, and sexual aids, learn about the diverse approaches to enhancing sexual satisfaction and body image. Emphasizing the critical role healthcare professionals must play in addressing these topics to provide comprehensive care and break through the barriers of taboo and stigma.

    With great resources and top tips on how to approach communications with patients and their partners about how treatment will impact sexuality.

    We hope you enjoy listening.

    For news and podcast updates subscribe to The Oncology Newsletter, a free weekly publication for healthcare professionals with an interest in oncology. Click here to subscribe.

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    Unlock the secrets of the ever-evolving oncology landscape as Professor Craig Underhill, Dr Kate Clarke and Professor Christopher Jackson take us through another brilliant OJC update.

    Craig reviews new sarcoma research and also looks at a mortality comparison study of six high-income Anglophone countries. Kate delves into the exciting advancements in precision oncology, particularly the impacts of on children, adolescents, and young adults. CJ looks at a groundbreaking cohort study from Christchurch, New Zealand, revealing how Faecal Immunochemical Tests (FIT) could revolutionise colonoscopy referrals and optimise healthcare resources.

    Craig announces his career change, stepping away from clinical practice to a research-centric career, after many years of dedicated practice and impassioned advocacy for regional and rural patients. His passion for changing the healthcare scene in regional Australia, particularly during the COVID-19 pandemic, shines through as he reflects on the emotional yet rewarding transition.

    With a focus on enhancing patient care, this episode of The Oncology Journal Club provides a comprehensive look at how precision medicine and innovative research are shaping the future of oncology.

    For papers, bios and other links visit the Show Notes on our website.

    For the latest oncology news visit www.oncologynews.com.au.

    We invite healthcare professionals to join The Oncology Network for free - you'll also receive our free weekly publication The Oncology Newsletter.

    The Oncology Podcast - An Australian Oncology Perspective

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    Curious about the latest breakthroughs in oncology treatment? Prepare to have your perspective shifted and hopefully a few laughs too, as we dissect the most compelling research and clinical insights with our expert hosts, Professor Craig Underhill, Dr. Kate Clarke, and Professor Christopher 'CJ' Jackson.

    Today’s episode covers an eclectic mix of papers. Craig tackles patient-reported outcomes. Kate looks at oral cannabis for nausea and vomiting. And CJ reviews the ASCO Guidelines for the management of locally advanced rectal cancer.

    Plus each Host presents their favourite Quick Bite papers.

    For papers, bios and other links visit the Show Notes on our website.

    For the latest oncology news visit www.oncologynews.com.au.

    We invite healthcare professionals to join The Oncology Network for free - you'll also receive our free weekly publication The Oncology Newsletter.

    The Oncology Podcast - An Australian Oncology Perspective

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    Curious about the latest breakthroughs in oncology treatment? Prepare to have your perspective shifted and hopefully a few laughs too, as we dissect the most compelling research and clinical insights with our expert hosts, Professor Craig Underhill, Dr. Kate Clarke, and Professor Christopher Jackson.

    Today’s episode covers an eclectic mix of papers from many different specialities. Craig tackles ASCO non-small cell lung cancer recommendations, sarcomas in Brazil and cardiovascular risks in cancer patients.

    Kate dives into endometrial cancer, the HIMALAYA study and CAR-T.

    CJ looks at colon cancer, pancreatic cancer and pain management.

    And a shout-out to our Series 1 hosts Professor Eva Segelov and Professor Hans Prenen who both have papers in today’s episode!

    For papers, bios and other links visit the Show Notes on our website.

    For the latest oncology news visit www.oncologynews.com.au.

    We invite healthcare professionals to join The Oncology Network for free - you'll also receive our free weekly publication The Oncology Newsletter.

    The Oncology Podcast - An Australian Oncology Perspective

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    Welcome to the latest episode of Supportive Care Matters. Join Medical Oncologist Professor Bogda Koczwara AM and Dr. David Mizrahi, Exercise Physiologist and Research Fellow at the Daffodil Center, University of Sydney.

    Learn how precisely prescribed exercise can transform not just the physical health but also the clinical outcomes for cancer patients. We break down the distinctions between exercise and physical activity, showing how each contributes uniquely to improved mood, heart health, muscle strength and metabolic health.

    Dr. Mizrahi shares ground-breaking insights on how integrating exercise into cancer treatment regimes can not only enhance survival rates and reduce chronic disease risks but also alleviate the financial burdens on healthcare systems.

    Discover innovative methods to incorporate physical activity into cancer treatments, such as the use of mini bikes during chemotherapy at Chris O'Brien Lifehouse. We discuss exciting, play-based exercise initiatives for children undergoing cancer treatment and the importance of healthcare providers setting a proactive example.

    By the end of this episode, you'll come away inspired by practical strategies and real-world examples, reaffirming that every bit of movement counts on the journey to better health for cancer patients.

    Visit www.oncologynews.com.au for show notes and more information about Supportive Care Matters!

    This conversation is proudly produced by The Oncology Network.

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    Discover the latest breakthroughs from ASCO 2024 with The Oncology Journal Club team!

    Professor Chris Jackson, who, despite battling the infamous man flu, brings his A-game to dissect the NADINA study. Learn how neoadjuvant ipilimumab and nivolumab are transforming resectable stage 3 melanoma treatment with a remarkable 26 percentage point gain in 12-month event-free survival. Chris shines a spotlight on the innovative design of this trial and its promising implications for reducing treatment duration and financial strain.

    But that's just the beginning. Dive into the long-term data from the COMBI-AD study, where we explore the enduring effects of dabrafenib and trametinib on melanoma patients with V600 mutations. We’ll unpack the nuances between V600E and V600K mutations and discuss how these findings could shift clinical practice towards more effective strategies. Plus, Dr Kate Clarke talks us through the latest on the A-BRAVE study in triple-negative breast cancer and its quest for improved disease-free survival rates.

    And of course our Host Professor Craig Underhill unpacks the incredible paradigm-shifting data in lung cancer that could redefine clinical protocols. He also explores the expanding frontier of telehealth in palliative care and its game-changing potential, especially for remote communities.

    Covering a whopping 17 abstracts, this second ASCO 2024 Special Episode is packed with critical insights and forward-thinking discussions that no oncology professional should miss. Join us for a thought-provoking and entertaining journey through the latest in cancer research and care.

    For papers, bios and other links visit the Show Notes on our website.

    For the latest oncology news visit www.oncologynews.com.au.

    We invite healthcare professionals to join The Oncology Network for free - you'll also receive our free weekly publication The Oncology Newsletter.

    The Oncology Podcast - An Australian Oncology Perspective

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    Imagine having the latest breakthroughs in oncology from the ASCO 2024 conference delivered with humour, expert insight and personal stories. That's exactly what you'll get in this special episode of the Oncology Journal Club, where Professor Craig Underhill, Dr. Kate Clark, and Professor Christopher Jackson dissect the most impactful research in a uniquely engaging way.

    Going beyond the usual presentations, with analysis of practice changing presentations aka 'The Bangers!'

    From Professor Jackson's cultural adventures in Invercargill to Dr. Clark's firsthand experiences on the bustling floors of Chicago's conference halls, we bring you an unforgettable review of the key highlights, including the Destiny Breast 06 abstract.

    No other ASCO Commentary is going to combine Spotify playlists and visions of senior oncologists in mankinis with high-level expert analysis. The OJC team are famous for reviewing oncology research with unique humour and entertaining insights.

    So join us for Part 1 of the ASCO Special from The Oncology Journal Club Podcast!

    For papers, bios and other links visit the Show Notes on our website.

    For the latest oncology news visit www.oncologynews.com.au.

    We invite healthcare professionals to join The Oncology Network for free - you'll also receive our free weekly publication The Oncology Newsletter.

    The Oncology Podcast - An Australian Oncology Perspective

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    Welcome to the latest episode of Supportive Care Matters. Join Medical Oncologist Professor Bogda Koczwara AM and advocate Matthew Zachary, founder of Stupid Cancer and the creative force behind the documentary "Cancer Mavericks."

    Matthew shares the profound journeys of pioneers who transformed cancer survivorship from the 1960s to the present day. From exhaustive research to heartwarming interviews, discover the intricate process of honouring those who fought tirelessly to improve the lives of cancer patients and survivors.

    This episode traces the evolution of cancer survivorship, from the early days of merely surviving to today's focus on enhancing life quality. Explore advancements in genomics, the importance of consumer protection and the nuanced approaches required for effective cancer prevention and treatment.

    As we navigate through the personal and socio-economic implications of cancer survivorship, we offer crucial advice for newly diagnosed patients and those just completing treatment. Uncover strategies for overcoming the bureaucratic challenges of the American healthcare system and the necessity for mutual empathy between patients and providers.

    As we conclude, we discuss the need for another revolution in society's attitude toward cancer survivors, underscoring the vital role of community support - and the new role of consumer advocacy - in making the cancer experience a little less daunting for others.

    Visit www.oncologynews.com.au for show notes and more information about Supportive Care Matters!

    This conversation is proudly produced by The Oncology Network.

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    Join us on this episode of The Oncology Journal Club Podcast as we dissect the latest research that point to new standards of care.

    Join our esteemed Hosts, Professor Craig Underhill, Dr. Kate Clarke and Professor Christopher Jackson for the low down on the latest oncology papers.

    Craig looks at how three-agent regimens have revolutionised the treatment of metastatic hormone-sensitive prostate cancer. Kate asks how alcohol affects lethal prostate cancer risk. And CJ explores the promising results of adjuvant pembrolizumab in resected renal cell carcinoma with his typical in-depth, high-speed and highly nuanced analysis.

    Then we shift gears to our popular Quick Bites section (and yes, CJ is at the crackers again!). We look at the halted KeyVibe Adjuvant Melanoma Study, a Chinese trial on oesophageal squamous cell carcinoma, a small trial on dual tyrosine kinase inhibitors for BRAF mutant stage 3 melanoma, the TOPAS1 trial on divalimab in advanced biliary tract cancer and rural clinical trial enrolment.

    As always, The OJC team provide a robust analysis of the latest findings in oncology research. Tune in for a comprehensive, insightful and entertaining review of cutting-edge oncology developments.

    For papers, bios and other links visit the Show Notes on our website.

    For the latest oncology news visit www.oncologynews.com.au.

    We invite healthcare professionals to join The Oncology Network for free - you'll also receive our free weekly publication The Oncology Newsletter.

    The Oncology Podcast - An Australian Oncology Perspective

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    Welcome to the latest episode of Supportive Care Matters. Join Medical Oncologist Professor Bogda Koczwara AM and Dr. Wanda Cui as they dive deep into the often overlooked complexities of ovarian toxicity in cancer care.

    In this engaging conversation, Bogda and Wanda go beyond the surface discussions of fertility to explore the vital importance of a woman's overall ovarian health after cancer treatment. They discuss the far-reaching effects of early menopause triggered by cancer therapies on cardiovascular and bone health, shedding light on the significance of safeguarding reproductive potential through fertility preservation methods.

    Together, they tackle the challenges of measuring ovarian function in clinical practice, highlighting the disparities in menstrual recovery among different age groups post-treatment. By exploring predictive values and the effectiveness of indicators like menstruation, pregnancy rates, and hormonal levels, they provide insights into personalised clinical practices essential for addressing individual patient needs.

    The discussion also emphasises the urgent need for improved research in ovarian toxicity, particularly within breast cancer trials where data is lacking. Supportive Care Matters isn't just a podcast; it's a call to action for greater patient involvement and policy change in cancer care.

    Join us as we navigate the complexities of ovarian toxicity and strive for better support and care for cancer patients everywhere. Visit www.oncologynews.com.au for show notes and more information about Supportive Care Matters!

    This conversation is proudly produced by The Oncology Network.

    TO VIEW SHOW NOTES AND MORE INFORMATION ABOUT SUPPORTIVE CARE MATTERS, HEAD TO WWW.ONCOLOGYNEWS.COM.AU

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    How do cancer outcomes in New Zealand compare to Australia? How can we optimise post-neoadjuvant treatment in patients with early breast cancer who achieve pathologic complete response? Does bevacizumab improve efficacy when administered with platinum combination therapy and atezolizumab in patients with advanced nonsquamous non small cell lung cancer? And how do AI chatbots perform when asked for cancer treatment recommendations?

    Welcome to The Oncology Journal Club Podcast – your go-to source for in-depth discussions on the latest oncology research tailored for medical professionals.

    Join our esteemed Hosts, Professor Craig Underhill, Dr. Kate Clarke and Professor Christopher Jackson for the low down on the latest oncology papers.

    They also discuss ASCO guidelines, inequities, financial conflicts and environmental issues.

    But that's not all – we also add a touch of whimsy to the episode, rounding off with a fun song inspired by Craig's latest half marathon, crafted in the style of Taylor Swift (courtesy of CJ's favourite new lyric-writing machine, Chat GPT!).

    Tune in to The Oncology Journal Club Podcast for an informative and entertaining journey through the world of oncology research and practice.

    For papers, bios and other links visit the Show Notes on our website.

    For the latest oncology news visit www.oncologynews.com.au.

    We invite healthcare professionals to join The Oncology Network for free - you'll also receive our free weekly publication The Oncology Newsletter.

    The Oncology Podcast - An Australian Oncology Perspective


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    Welcome to the ninth episode of Supportive Care Matters, a podcast Hosted by Medical Oncologist Professor Bogda Koczwara AM from Adelaide, Australia.

    Navigating the silent struggle that many cancer survivors face, this episode promises insights into the lesser-known yet impactful world of chemotherapy-induced peripheral neuropathy (CIPN).

    With the expertise of Professor David Goldstein and Associate Professor Susanna Park, this episode sheds light on how CIPN disrupts daily life in ways that go unnoticed by the medical community.

    From the nuanced challenges of assessing the severity of this condition to the cognitive toll it takes on patients, Bogda leads a discussion on the critical need for sensitive and precise management strategies that can truly make a difference.

    The conversation takes a deep look into the tools and techniques that are transforming how we understand and measure CIPN. Our guests articulate the importance of patient-reported experiences in guiding interventions and the potential benefits of exercise in mitigating neuropathic symptoms. Through this dialogue, we recognise the dedication and collaborative efforts that are pushing the envelope in neuropathy research and care, offering a glimmer of hope for those battling with the long-lasting effects of their cancer treatments.

    This episode stands as a testament to the resilience of the human spirit and the ongoing efforts to provide supportive care that truly matters. Subscribe and like to join our mission of bringing these crucial conversations to the forefront and make supportive care matter.

    This conversation is produced by The Oncology Network.

    TO VIEW SHOW NOTES AND MORE INFORMATION ABOUT SUPPORTIVE CARE MATTERS, HEAD TO WWW.ONCOLOGYNEWS.COM.AU

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    The Oncology Journal Club - Delivering Oncology News Differently

    The Oncology Podcast, part of The Oncology Network, is proud to present Episode 3 in the second series of The Oncology Journal Club Podcast.

    Dr Kate Clarke explores a clinical conundrum with the latest insights on neo-adjuvant immunotherapy for DMMR, MSI-high GI cancers, discussed with the clarity and depth you've come to expect from our team. For Professor Craig Underhill's main paper segment, Dr. Ashray Gunjur drops by to discuss the microbiome's predictive power in immunotherapy responses, Professor Christopher Jackson delves into the OPRA study's latest findings on chemo-radiotherapy sequencing for rectal cancer, bringing to light the pivotal role of patient-centred discussions.

    In Quick Bites, the discussion hits home with the three S's—sitting, shitting, and sex—and their profound impact on post-cancer quality of life. Highlighting the importance of comprehensive support systems in these often-overlooked areas, we also dissect the worrying trend of early-onset colorectal cancer and its broader implications. With a review of a study about the duration of immunotherapy in non-small cell lung cancer, this episode promises to fuel ongoing debates on treatment duration and patient outcomes, highlighting our commitment to keeping you at the forefront of oncology discourse.

    The conversation takes a crucial turn as we tackle the uncomfortable yet necessary topic of presenting unfunded treatment options in oncology, exposing the delicate balance healthcare professionals must maintain in an era marked by scarce resources and rising demands.

    For papers, bios and other links visit the Show Notes on our website.

    For the latest oncology news visit www.oncologynews.com.au.

    We invite healthcare professionals to join The Oncology Network for free - you'll also receive our free weekly publication The Oncology Newsletter.

    The Oncology Podcast - An Australian Oncology Perspective

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    The Oncology Journal Club Podcast presents The OJC Meets Ashray Gunjur

    The Oncology Podcast, part of The Oncology Network, is proud to present the return of The OJC Meets: sister series of The Oncology Journal Club podcast.

    Our Host Professor Craig Underhill meets Dr Ashray Gunjur as they share insights into the gut microbiome's role in predicting how patients will respond to cancer immunotherapies.

    Together, they unearth how the tiny worlds within us might hold the key to unlocking personalised medical approaches that are as unique as our microbial fingerprints.

    Ashray's expertise in analysing faecal microbiomes at the strain level using shotgun metagenomic sequencing is not just impressive—it's a game-changer for oncologists and patients alike, offering hope for more targeted, effective treatment regimens.

    For a link to the paper and speaker bios, visit the Show Notes on our website: oncologynetwork.com.au.

    And for the latest oncology news, visit www.oncologynews.com.au.

    We invite healthcare professionals to join The Oncology Network for free - you'll also receive our free weekly publication The Oncology Newsletter.

    The Oncology Network - Delivering Oncology News Differently

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    The Oncology Journal Club - Delivering Oncology News Differently

    The Oncology Podcast, brought to you by The Oncology Network, is proud to present Episode 2 in the second series of The Oncology Journal Club.

    Our Host Professor Craig Underhill has a great interview on onco-burnout. Dr Kate Clarke talks us through breast cancer highlights from 2023 and Professor Christopher Jackson gets stuck into Prophylactic Radiation Therapy for High-Risk Asymptomatic Bone Metastases.

    We also have a fascinating selection of quick bites with the usual high-level analysis and entertaining banter.

    For papers, bios and other links visit the Show Notes on our website.

    For the latest oncology news visit www.oncologynews.com.au.

    We invite healthcare professionals to join The Oncology Network for free - you'll also receive our free weekly publication The Oncology Newsletter.

    The Oncology Podcast - An Australian Oncology Perspective

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    Supportive Care Matters: A Podcast by Dr. Bogda Koczwara

    Welcome to the eighth episode of Supportive Care Matters, a podcast Hosted by Medical Oncologist Professor Bogda Koczwara AM from Adelaide, Australia.

    In this episode, Bogda chats to Professor Tom J Smith. They discuss the meaning of “supportive” versus “palliative” care and how to use these terms to overcome fear and stigma, and put patient’s needs first.

    This conversation is produced by The Oncology Network.

    TO VIEW SHOW NOTES AND MORE INFORMATION ABOUT SUPPORTIVE CARE MATTERS, HEAD TO WWW.ONCOLOGYNEWS.COM.AU

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    Welcome to Episode 27 of The Oncology Podcast's Experts On Point series, brought to you by The Oncology Network.

    Endometrial cancer is the most common gynaecological cancer in Australia and advanced disease and early on set disease is increasing.

    In today’s episode, our Host Rachael Babin is joined by Professor Linda Mileshkin Director of Medical oncology at the Peter MacCallum Cancer Centre in Melbourne, Australia.

    They discuss new treatment options, clinical trials and collaborative research efforts such as the EDEN initiative.

    They also discuss stigma, shame and society’s silence around gynaecological cancers.

    We hope you enjoy listening.

    For news and podcast updates subscribe to The Oncology Newsletter, a free weekly publication for healthcare professionals with an interest in oncology. Click here to subscribe.

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