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Devon Grey and David Knight (University of Alabama, Birmingham) join AJP Audio to discuss how exposure to discrimination impacts neural reactivity to stress and psychological distress in adolescents. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin joins us to discuss the rest of the December issue of AJP.
00:36 Grey and Knight interview 02:41 Demographics of the cohort 03:46 Neurobiological mechanisms of discrimination impacts 06:14 Racial discrimination and mental health impacts 09:34 Discrimination as a chronic stressor and prolonged activation of the stress response system 10:45 Limitations 13:52 Further research 14:38 Kalin interview 14:52 Grey et al. 17:35 Sippel et al. 18:06 Fox and Shackman 19:42 Kliemann et al. 22:16 Kamboj et al. 27:07 Pathak et al.Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it.
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Dr. Phuc Le (Cleveland Clinic, Case Western Reserve University, Cleveland) joins AJP Audio to discuss racial, ethnic, and sociodemographic disparities in treatment in alcohol use disorder among participants of the All of Us cohort. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin joins to discuss the rest of the November issue, which takes a close look at issues surrounding substance use disorders.
00:41 Le interview 01:52 Disparities in treatment of AUDs in the US 03:43 What is the VA system doing right? 05:25 All of Us 06:39 Immediate clinical implications 08:15 Limitations 09:38 Further research 10:55 Kalin interview 11:07 Le et al. 13:44 Imperio et al. 14:43 McClure et al. 17:23 Perlman et al. 20:57 Savage et al. 24:17 Compton et al.Transcript
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Dr. Bodyl Brand (Oxford University, UK) joins AJP Audio to discuss the effectiveness of menopausal hormone therapy in preventing psychosis relapse in women with schizophrenia and schizoaffective disorder. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin takes us through the rest of the October issue of the American Journal of Psychiatry, which focuses on other issues touching psychosis and schizophrenia spectrum disorders.
01:05 Brand interview 03:08 MHT and potential side effects in schizophrenia treatment 06:16 Estrogen and psychosis prophylaxis 07:44 MHT effectiveness 10:15 Clinical implications 11:27 Strengths and limitations 13:47 The need for further study 15:54 Further research 17:24 Kalin interview 17:47 Brand et al. 20:17 Partanen et al. 23:54 Moran et al. 26:48 Gallucci et al. 30:38 Arion et al.Transcript
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Dr. Jessica Salvatore (Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey) joins AJP Audio to discuss peer social genetic effects and their impact on alcohol and substance use, anxiety, and major depressive disorders in adolescents. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin takes us through the rest of the September issue of the American Journal of Psychiatry.
00:52 Salvatore interview 02:49 Can the genetic makeup of other people impact your risk for psychiatric conditions? 04:12 Impact on genetic predisposition 05:12 Why look at these effects through a genetic lens? 07:17 Limitations 10:05 Clinical implications 12:40 Further research 13:32 Kalin interview 13:47 Salvatore et al. 15:54 Dalhuisen et al. 19:23 Hess et al. 24:14 Larsen et al. 26:43 Schwippel et al.Transcript
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Dr. Evan Krueger (Tulane University School of Social Work) joins AJP Audio to discuss the impact of sexual identity change and continuity on the mental health and substance use of adults who identify as a sexual minority. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin discusses the rest of the August issue of AJP.
00:52 Krueger interview 02:49 The Generations Study 04:21 How the sample differed 05:42 Differences between male and female, monosexual and plurisexual 07:53 Clinical implications for this population 09:39 Limitations 11:11 Life course and societal changes as potential factors? 13:05 Further research 14:31 Kalin interview 14:37 Krueger et al. 17:21 Amstadter et al. 20:45 Hilbert et al. 23:13 Bommersbach et al. 25:49 Zhou et al.Transcript
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Dr. Lina Jonsson (Sahlgrenska Academy at University of Gothenburg, Sweden) joins AJP Audio to discuss the association of occupational dysfunction and hospital admissions with polygenic profiles in patients with bipolar disorder. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin discusses the rest of the July issue of AJP.
00:45 Jonsson interview 04:35 Occupational dysfunction and hospitalization in bipolar disorder 05:29 Crossover between groups in patients with schizophrenia spectrum disorder 06:37 Clinical implications for working with patients with bipolar disorder 07:46 Limitations 09:03 Future research 10:14 Kalin interview 10:31 Jonsson et al. 13:43 Baum et al. 15:00 Kang et al. 18:10 Rohde et al. 22:06 Ironside et al. 26:30 Chen et al.Transcript
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Ms. Sara Tramazzo (Stony Brook University) joins AJP Audio to discuss the long-term outlook for patients with schizophrenia spectrum disorders and other psychotic disorders over the course of 25 years. Afterwards, Dr. Ned Kalin joins to discuss the rest of the June issue of AJP.
00:50 Tramazzo interview 01:55 Lower levels of recovery and remission than other long-term studies 03:01 Difficulties of following patients in long-term studies 04:35 Differences between recovery and remission 05:54 Clinical implications 07:49 Limitations 10:21 Follow up periods 11:17 Further research 12:39 Kalin interview 12:53 Tramazzo et al. 15:51 Erwin et al. 18:59 Van der Pluijm et al. 20:47 Vita et al. 23:08 Tamon et al. 25:06 Norman et al.Transcript
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Dr. ReJoyce Green (Medical University of South Carolina, Charleston, SC) joins AJP Audio to discuss predictors of substance use initiation in a large cohort of early adolescents. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin speaks with AJP Deputy Editor Dr. Kathleen Brady about the May issue of AJP, a special issue guest edited by Dr. Brady focusing on latest developments in the understanding and treatment of substance use disorders.
Transcript
00:48 Green interview 03:04 Why is it important to study substance use initiation? 04:06 Social and family-related factors versus imaging and neurocognitive factors 05:58 Age and cohort concerns 07:15 Religious participation as a predictive factor 09:04 Clinical implications 11:03 Limitations 12:24 What’s next for your research? 13:36 Kalin and Brady interview 17:09 Green et al. 19:52 Morley et al. 23:34 Radoman et al. 26:21 Hoffman et al. 29:00 Blalock et al.Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it.
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Dr. Soonjo Hwang (University of Nebraska Medical Center) joins AJP Audio to discuss the response to intranasally-administered oxytocin in youths with severe irritability.
00:56 Hwang interview 02:09 Effects of oxytocin 05:45 Intranasal oxytocin 07:04 Potential adverse effects of oxytocin 08:08 Imaging 08:58 Preliminary investigations and clinical implications 09:51 Limitations 10:14 Further research 11:00 Kalin interview 11:33 Hwang et al. 14:43 Leibenluft et al. 15:39 Aggarwal et al. 18:22 Pezzoli et al. 21:34 Kendler et al. 23:30 Hou et al.Transcript
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Dr. Drew Rothenberg (Duke University, Durham, NC) joins AJP Audio to discuss the long term, intergenerational impacts of the Fast Track program, and whether the mental health intervention lead to lasting improvements in mental health, including in the participants own children.
00:49 Rothenberg interview 04:36 A null result? 07:13 At risk children from high risk neighborhoods 08:00 Limitations 09:17 Demand for childhood mental health services and clinical implications 11:10 Further research 13:59 Kalin interview 14:12 Rothenberg et al. 16:12 Haller et al. 18:49 Poirot et al. 20:55 Ainsworth et al. 23:20 Rosenqvist et al.Transcript
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Dr. Ofir Livne (Columbia University, New York) joins AJP Audio to discuss recent trends in the prevalence of cannabis use disorder in US veterans with and without psychiatric disorder diagnosis. Dr. Ned Kalin joins afterwards to discuss how the rest of the February issue of AJP touches on cannabis use disorder and other substance use disorders.
00:31 Livne interview 03:16 Changes in the legal landscape surrounding cannabis use 05:17 The complex association between cannabis use and psychiatric disorders 07:20 Clinical implications 08:02 Limitations 09:44 Future directions for research 10:13 Kalin interview 10:30 Livne et al. 12:30 Gustafson et al. 14:44 Garland et al. 16:10 Wilson et al. 18:06 Huang et al.Transcript
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Dr. Jaclyn Ross, Ms. Jordan Barone, and Dr. Tory Eisenlohr-Moul (University of Illinois at Chicago) join AJP Audio to discuss the impact of the menstrual cycle on suicide ideation and planning in psychiatric patients with suicidality. Afterwards, American Journal of Psychiatry Editor-in-Chief Dr. Ned Kalin brings us up to date on the rest of the January issue of AJP.
Transcript
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Dr. Aaron Samuel Breslow (Montefiore Medical Center and Albert Einstein College of Medicine) joins AJP Audio to discuss the racial and ethnic disparities in the impact of COVID-19 and pandemic related stressors and adverse mental health outcomes on health care workers in the Bronx, New York. Following we’ll once again check in with American Journal of Psychiatry Editor-in-Chief Dr. Ned Kalin on the rest of the December issue of AJP.
Breslow interview [00:56] Why look at the Bronx in particular? [2:54] COVID-19 related stressors and pandemic related stressors [05:27] Unrelated adverse mental health outcomes [07:40] Limitations [09:29] Policy considerations [11:39] Further research [14:22] Kalin interview [16:17] Breslow et al. [16:34] Guintivano et al. [18:36] Copeland et al. [22:10] Joseph et al. [25:21] Shim and Rodriguez [27:15]Transcript
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Dr. Winston Chung (Kaiser Permanente Northern California) joins AJP Audio to discuss inequalities in the diagnosis of psychotic disorders between racial and ethnic groups in a large cohort. Afterwards, we’ll once again be joined by American Journal of Psychiatry Editor-in-Chief, Dr. Ned Kalin, to discuss the rest of the November issue of AJP, which focuses on different aspects of psychotic disorder.
Chung interview [00:30] Structural racism and missing socioeconomic strata [02:58] Effective and non-effective psychosis [04:20] Limitations [05:48] Differential rates of treatment and non-treatment [06:58] Policy implications [07:40] Further research [08:31] Kalin interview [08:58] Chung et al. [09:14] Rødevand et al. [11:27] Cao et al. [14:07] Smucny et al. [16:18] Cannon [17:03]Transcript
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Dr. Luis Farhat and Dr. Guilherme V. Polanczyk (University of São Paulo, Brazil) join AJP Audio to discuss the impact of socioenviromental factors, emotional dysregulation, and other factors impact neurodevelopment in children. Afterwards, we’ll once again be joined by American Journal of Psychiatry Editor-in-Chief, Dr. Ned Kalin, to discuss the rest of the September issue of AJP and what brings it together.
Farhat and Polanczyk interview [00:54] Comorbidities and associations [03:22] Twins Early Development Study and the Avon Longitudinal Study of Parents and Children [04:47] Limitations [07:35] Clinical Implications [09:32] Further research [11:48] Kalin interview [13:20] Farhat et al. [13:35] Nguyen et al. [15:37] Docherty et al. [18:02] Chatzinakos et al. [20:18] Marr et al. [24:06]Transcript
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Dr. Antony Chum (York University, Toronto) joins AJP Audio to discuss disparities in suicide-related behaviors between sexual orientations by gender in a large cohort from the province of Ontario. Afterwards, we’ll once again be joined by American Journal of Psychiatry Editor-in-Chief, Dr. Ned Kalin, to discuss the rest of the September issue of AJP and what brings it together.
Transcript
Chum interview [00:34] Results [02:14] Using a large data set [03:21] Correcting the limitations of previous research [04:40] Taking changing societal circumstances into account [06:11] Immediate clinical implications [07:57] What’s next for your research? [09:47] Kalin interview [11:23] Chum et al. [11:34] Widge et al. [13:15] Russell et al. [15:06] Deligiannidis et al. [15:34] Clayton et al. [18:41] Kumar et al. [19:59]Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Stitcher, Spotify, or wherever you listen to it.
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Dr. Lucy S. King (Tulane University School of Medicine, New Orleans) and Dr. Kathryn L. Humphreys (Vanderbilt University, Nashville) join AJP Audio to discuss the long term impacts of a pioneering randomized controlled trial that looked at the impacts of institutional care versus home foster care in children, the Bucharest Early Intervention Project. They also discuss the impacts of deprivation on children’s development and mental health, and the thorny ethics of research involving children.
Transcript
The impact of deprivation [01:19] Bucharest Early Intervention Project and the ethics of research involving children [04:43] Analyzing diverse data [08:57] Why revisit this trial? [16:05] Long term impacts of the intervention [18:39] Limitations [23:22] Policy implications [26:16] Further research [30:18]Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Stitcher, Spotify, or wherever you listen to it.
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Dr. Dylan J. Jester (VA Palo Alto Medical Center in Palo Alto, California) joins AJP Audio to discuss the differential impact of selected social determinants of health on the mental health outcomes of older Black, White, and Latinx adults in the United States. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin discusses how issues of substance use disorder draw together the rest of the July issue.
Transcript
Jester interview [00:48] Which social determinants of health did you focus on? [03:31] Societal factors versus individual criteria [04:30] Data [05:25] Lessons for policymakers [06:30] Limitations [07:37] What’s next for your research? [08:36] Kalin interview [10:11] Jester et al. [10:21] Dienel et al. [12:50] Jacob et al. [16:15] Joshi et al. [18:50]Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Stitcher, Spotify, or wherever you listen to it.
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Dr. Mark Olfson (Columbia University) discusses the links between opioid prescribing and suicide risk in the United States. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin discusses how issues of substance use disorder draw together the rest of the June issue.
Transcript
Olfson interview [00:46] Geographic commuting areas [01:06] Opioid prescription measures [02:10] Rates of opioid prescription and suicide [03:27] Youngest age cohorts as outliers [04:19] Regional variations [04:57] Limitations [05:17] Clinical implications [05:55] What’s next for your research? [06:21] Kalin interview [06:42] Olfson et al. [07:00] Vickers-Smith et al. [08:36] Rognli et al. [10:44] Garrison et al. [12:51]Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Stitcher, Spotify, or wherever you listen to it.
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Ms. Gal Arad (Tel Aviv University, Tel Aviv, Israel) discusses a non-pharmacological intervention for the treatment of social anxiety disorder in comparison with standard care. Afterwards, we’ll be joined once again by AJP Editor-in-Chief Dr. Ned Kalin to discuss the rest of the May issue.
Transcript
Arad interview [00:18] What were your results? [02:11]
Reduction in dwell time on threatening faces [03:36]
Limitations [04:09]
Immediate clinical implications [05:27]
Further research [05:58]
Kalin interview [06:37]
Arad et al. [06:55]
Grant et al. [09:07]
Reddy et al. [10:59]
Taipal et al. [13:28]
Buchanan and Krane [14:39]
Brandt et al. [15:41]Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Stitcher, Spotify, or wherever you listen to it.
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