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In this episode, Stacey B. Trooskin, MD, PhD, MPH, Mark S. Sulkowski, MD, FIDSA, FAASLD, and Ronni Marks discuss hepatitis C virus (HCV) screening and treatment, focusing on people who use drugs, and highlight the following topics:
Screening recommendationsStrategies to improve HCV screeningHCV testingTreatment goalsStrategies to improve HCV treatment uptakePresenters:
Stacey B. Trooskin, MD, PhD, MPH
Executive Medical Officer
Mazzoni Center
Faculty, University of Pennsylvania
Perelman School of Medicine
Philadelphia, PennsylvaniaMark S. Sulkowski, MD, FIDSA, FAASLD
Professor of Medicine
Director, Division of Infectious Diseases Johns Hopkins Bayview Medical Center
Johns Hopkins University School of Medicine
Baltimore, MarylandRonni Marks
Founder/Director, The Hepatitis C Mentor and Support Group (HCMSG)
Patient Advocate
New York, New YorkLink to full program:
https://bit.ly/4grbwPT -
Listen in as Stephen Cantrill, MD, FACEP; Rajesh T. Gandhi, MD; and Payal K. Patel, MD, MPH, FIDSA, discuss best practices in treating patients hospitalized with mild to moderate COVID-19, including:
Current guidelines from the Infectious Diseases Society of America and National Institutes of Health How to optimize therapy selection based on patient risk factors, including key data supporting best practicesA detailed patient case to illustrate key takeawaysPresenters:
Stephen Cantrill, MD, FACEP
Associate Director and Medical Director (Retired)
Department of Emergency Medicine
Denver Health Medical Center
Associate Professor
Department of Emergency Medicine
University of Colorado Health Sciences Center
Denver, ColoradoRajesh T. Gandhi, MD
Massachusetts General Hospital
Professor of Medicine
Harvard Medical School
Boston, MassachusettsPayal K. Patel, MD, MPH, FIDSA
Systemwide Director of Antimicrobial Stewardship
Associate Professor, Division of Infectious Diseases
Intermountain Health
Salt Lake City, UtahLink to full program:
https://bit.ly/4fs7HcbGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.
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Clinical gaps in the treatment of pruritus in primary biliary cholangitis (PBC) remain. In this episode, taken from a recent symposium, Marlyn J. Mayo, MD; Stuart C. Gordon, MD; and Pam Rivard, RN, a person living with PBC, discuss emerging therapies currently in clinical trials for the management of this disease that can dramatically affect patients’ quality of life.
Listen as they discuss:
Gaps in current managementPatient perspectives: why we should not dismiss itching as an underlying psychologic problemPPAR agonists and how they affect pruritusBEZURSO and FITCH ELATIVEENHANCE and RESPONSEIBATs (inhibitors of bile acid transport)GLIMMERCommon questionsPresenters:
Marlyn J. Mayo, MD
Professor of Internal Medicine
Division of Digestive & Liver Diseases
UT Southwestern Medical Center
Dallas, TexasStuart C. Gordon, MD
Professor of Medicine
Wayne State University School of Medicine
Director, Division of Hepatology
Henry Ford Health
Detroit, MichiganPam Rivard, RN
Person living with PBCLink to full program:
https://bit.ly/3Dnfb2E -
Although there is currently no FDA-approved treatment for pruritus in primary biliary cholangitis (PBC), symptoms can be mitigated with nonpharmacologic or pharmacologic agents. In this episode, Marlyn J. Mayo, MD; Stuart C. Gordon, MD; and Pam Rivard, RN, a person living with PBC, discuss the clinical management of pruritus in PBC, including:
Pruritus assessment toolsOptimal use of tools, including frequency of assessmentCurrent management of pruritusNonpharmacologic interventionsPharmacologic agentsStrategies to optimize assessment and management of pruritusCollaborative careDevelopment of a treatment planOngoing assessment and adjustment of therapyResources and support for patientsPresenters:
Marlyn J. Mayo, MD
Professor of Internal Medicine
Division of Digestive & Liver Diseases
UT Southwestern Medical Center
Dallas, TexasStuart C. Gordon, MD
Professor of Medicine
Wayne State University School of Medicine
Director, Division of Hepatology
Henry Ford Health
Detroit, MichiganPam Rivard, RN
Person living with PBCLink to full program:
https://bit.ly/3Dnfb2E -
In this episode, Marlyn J. Mayo, MD; Stuart C. Gordon, MD; and Pam Rivard, RN, a person living with primary biliary cholangitis (PBC), discuss the burden of pruritus in PBC and the impact it has on quality of life, including both physical and mental health, from a patient’s perspective.
Presenters:
Marlyn J. Mayo, MD
Professor of Internal Medicine
Division of Digestive & Liver Diseases
UT Southwestern Medical Center
Dallas, TexasStuart C. Gordon, MD
Professor of Medicine
Wayne State University School of Medicine
Director, Division of Hepatology
Henry Ford Health
Detroit, MichiganPam Rivard, RN
Person living with PBCLink to full program:
https://bit.ly/4gDGDaB -
In this episode, Jean-Michel Molina, MD, PhD, and Joseph J. Eron, Jr., MD, discuss results from key clinical trials on HIV prevention and treatment as well as sexually transmitted infection (STI) prevention presented at IDWeek and Glasgow 2024, including:
PURPOSE 1 and 2 comparing lenacapavir injection vs oral TDF/FTCTRIO Health Cohort and OPERA examining long-acting cabotegravir as PrEPDOLCE comparing DTG/3TC as first-line therapy in treatment-naive patients with HIVPRIDOX evaluating the use of DoxyPEP on STI incidence in men who have sex with men on PrEP
Presenters:Jean-Michel Molina, MD, PhD
Professor of Infectious Diseases
University of Paris Cité
Head of the Department of Infectious Diseases
Hospital Saint-Louis and lariboisière
Paris, FranceJoseph J. Eron, Jr., MD
Professor of Medicine, School of Medicine
Herman and Louise Smith Distinguished Professor
Chief, Division of Infectious Diseases
Director, Clinical Core, UNC Center for AIDS Research
Adjunct Professor of Epidemiology, Gillings School of Global Public Health
University of North Carolina at Chapel Hill
Chapel Hill, North CarolinaLink to full program:
https://bit.ly/3BBaZvJ -
In this episode, Christopher L. Bowlus, MD, discusses recent advances in the management of primary biliary cholangitis (PBC), including:
Treatment goalsUse of PPAR agonists for the treatment of PBCClinical trial results for elafibranor (ELATIVE), seladelpar (RESPONSE), and bezafibrate (BEZURSO)Presenter:
Christopher L. Bowlus, MD
Lena Valente Professor and Chief
Division of Gastroenterology and Hepatology
University of California Davis School of Medicine
Sacramento, CaliforniaLink to full program:
https://bit.ly/41tvSDuGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.
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In this episode, a transfemme nonbinary individual living with HIV shares her experience navigating the healthcare system, alongside her infectious disease physician, Michelle D. Collins-Ogle, MD, FAAP, FPIDS, AAHIVS. Hear them discuss key considerations when caring for gender-diverse individuals, including:
Understanding how people are more than just a diagnosis Prioritizing individuals’ needs and providing whole-person care using shared decision-makingStrategies to make an environment more affirming and welcoming How to be an ally to transgender individualsListen to the individual in front of youHear what they’re telling youMake sure they are being affirmed and seenLink to the full program:
https://bit.ly/3AAOGpvGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.
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Listen in as Rebekah Fenton, MD, MPH, and Sharon G. Humiston, MD, MPH, discuss strategies to achieve health equity in HPV vaccination, including:
Trends among males vs femalesMessaging considerations for those from diverse populations (eg, LGTBQ+ and rural communities)How healthcare professionals can address barriers to careThen, hear answers from the experts to frequently asked questions regarding HPV vaccination recommendations, timing, and example case studies.
Presenters:
Rebekah Fenton, MD, MPH
Adolescent Medicine Physician
Alivio Medical Center
Chicago, IllinoisSharon G. Humiston, MD, MPH
Director for Research
Associate Editor of IZ-Express
Immunize.org
Rochester, New YorkTo access all of our new podcast episodes, subscribe to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.
Follow along with the slides:
https://bit.ly/4flDxYbLink to full program:
https://bit.ly/4f06tW4 -
In this rapid webinar, Meredith E. Clement, MD, and Linda-Gail Bekker, MBChB, DTMH, DCH, FCP(SA), PhD, provide an overview of important topics and studies presented at HIVR4P 2024, including:
Expanding PrEP options based on results from PURPOSE 2, IMPOWER-22, IMPOWER-24, IPM 054, MTN-025/HOPE OLE, CATALYST, and the HPTN 084 substudyImplementing injectable PrEP based on results from PEPFAR, the USAID DISCOVER-Health LA CAB Demonstration Project in Zambia, and the LA CAB PrEP Rapid Start Model in Public Health ClinicsImproving PrEP uptake based on results from SPrEP and HPTN 091
Presenters:Meredith E. Clement, MD
Associate Professor
Infectious Diseases
Louisiana State University Health Sciences Center
New Orleans, LouisianaLinda-Gail Bekker, MBChB, DTMH, DCH, FCP(SA), PhD
Director and Professor, The Desmond Tutu HIV Centre, UCT
CEO, The Desmond Tutu Health Foundation
Cape Town, South AfricaTo access all of our new podcast episodes, subscribe to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.
Link to full program:
https://bit.ly/3NJIDSA -
Listen in as Rebekah Fenton, MD, MPH, and Sharon G. Humiston, MD, MPH, discuss strategies to improve your messaging techniques with the HPV vaccine, including:
Persisting in vaccine recommendation after initial refusalEducating patients and their families togetherEnsuring staff are trained to correctly answer questionsKnowing when interested patients in your state can consent to vaccination without needing parental consentPresenters:
Rebekah Fenton, MD, MPH
Adolescent Medicine Physician
Alivio Medical Center
Chicago, IllinoisSharon G. Humiston, MD, MPH
Director for Research
Associate Editor of IZ-Express
Immunize.org
Rochester, New YorkTo access all of our new podcast episodes, subscribe to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.
Follow along with the slides:
https://bit.ly/4flDxYbLink to full program:
https://bit.ly/4f06tW4 -
Listen in as Sharon G. Humiston, MD, MPH, discusses current trends in HPV, including:
Incidence and prevalence trends in the USSex-related features of HPV-attributable cancersHow HPV vaccination uptake can prevent certain types of cancerCurrent guidelines and recommendations for HPV vaccinationPresenter:
Sharon G. Humiston, MD, MPH
Director for Research
Associate Editor of IZ-Express
Immunize.org
Rochester, New YorkTo access all of our new podcast episodes, subscribe to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.
Follow along with the slides:
https://bit.ly/4flDxYbLink to full program:
https://bit.ly/4f06tW4 -
In this episode, Kathleen Page, MD, and Glenn J. Treisman, MD, PhD, discuss the interplay between addiction and HIV. Learn as they share their approaches to reframing the conversation about addiction and overcoming barriers to effective addiction care for people living with HIV.
Presenters:
Kathleen Page, MD
Professor
Infectious Diseases
Johns Hopkins School of Medicine
Baltimore, MarylandGlenn J. Treisman, MD, PhD
Eugene Meyer III Professor of Psychiatry and Medicine
Johns Hopkins University School of Medicine
Baltimore, MarylandDownloadable slides:
https://bit.ly/3TR3OVVProgram:
https://bit.ly/3WB2VCO -
In this episode, Alexander Wong, MD, FRCPC, discusses how to optimize treatment and engagement in care for individuals with HIV and substance use disorder, including:
Barriers to care for persons with substance use disorder Colocating HIV and other services (eg, addiction care medicine, social services) Leveraging a multidisciplinary approach to care Integrating a low-barrier model to foster an environment of open discussion Best practices for opioid agonist therapy implementationConsiderations for cultural dynamics to provide personalized treatment plansImportance of supporting his team membersPresenter
Alexander Wong, MD, FRCPC
Associate Professor
Division of Infectious Diseases
Department of Medicine
University of Saskatchewan
Regina, Saskatchewan, CanadaLink to full program:
https://bit.ly/3xicSeFGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.
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In this episode, Jennifer Cocohoba, PharmD, AAHIVP, and David Koren, PharmD, MPH, AAHIVP, FIDSA, cover the most impactful LA ART and LA PrEP clinical studies presented at AIDS 2024, including:
The PURPOSE 1 study of twice-yearly lenacapavir injections vs daily oral tenofovir as PrEP in cisgender womenAn open-label extension of HPTN 084 evaluating LA CAB safety during pregnancy48-week data from the IMPAACT 2017/MOCHA study of LA CAB + RPV in adolescents with HIVA substudy of FLAIR evaluating the efficacy, safety, and tolerability of SC self-administration of LA CAB + RPV
Presenters:
Jennifer Cocohoba, PharmD, AAHIVP
Professor of Clinical Pharmacy
Department of Clinical Pharmacy
University of California San Francisco School of Pharmacy
San Francisco, CaliforniaDavid Koren, PharmD, MPH, AAHIVP, FIDSA
Adjunct Clinical Professor
Temple University School of Pharmacy
Clinical Pharmacist Specialist
Temple University Health System
Philadelphia, Pennsylvania
To access all of our new podcast episodes, subscribe to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.See the full program here.
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In this episode, Tristan J. Barber, MA, MD, FRCP, and Glenn J. Treisman, MD, PhD, discuss the importance of screening, diagnosing, and treating PTSD in people with HIV. They illustrate their discussion through a patient case and provide strategies for accomplishing this, sharing their own experiences and approaches to thinking about PTSD, structuring appointments, and integrating care.
Presenters:
Tristan J. Barber, MA, MD, FRCP
Consultant in HIV Medicine
Royal Free London NHS Foundation Trust
Honorary Associate Professor
Institute for Global Health
University College London
London, United KingdomGlenn J. Treisman, MD, PhD
Eugene Meyer III Professor of Psychiatry and Medicine
Johns Hopkins University School of Medicine
Baltimore, MarylandDownloadable slides:
https://bit.ly/4dBu929Program:
https://bit.ly/3WB2VCO -
In this episode, Colleen F. Kelley, MD, MPH, and Jemma Samitpol discuss key considerations to improve the patient experience among transgender persons with HIV, including:
Unique circumstances faced by transgender people trying to access HIV care (eg, stigma, discrimination)Best practices to improve access and linkage to HIV careWays to integrate gender-affirming care into HIV careCreating a welcoming and inclusive environmentOffering same-day HIV treatmentAddressing potential drug–drug interactions with gender-affirming hormone therapy (GAHT), including ART and natural remediesUnderstanding and communicating expectations of GAHT (eg, treatment response, timing of effects)Providing information on the safety of gender-affirming surgeriesImportance of providing person-centered care (eg, mental health, substance abuse, housing, harm reduction)Strategies on how to promote a gender-affirming environment (eg, wearing pronoun buttons, staff training)Consequences to the lack of gender recognition lawsHow to “be an ally” for transgender people with HIVPresenters
Colleen F. Kelley, MD, MPH
Professor of Medicine
Division of Infectious Diseases
Department of Medicine
Co-Director, Emory Center for AIDS Research
Associated Dean for Research, Emory at Grady
Emory University School of Medicine
Atlanta, GeorgiaKritima Jemma Samitpol
Tangerine Clinic Supervisor
Institute of HIV Research and Innovation
Bangkok, ThailandGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast channel on Apple Podcasts, Google Podcasts, or Spotify.
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In this episode featuring faculty from the United States and Europe, Aadia I. Rana, MD, and Laurence Slama, MD, PhD, discuss the subtleties of deciding among HIV treatment options in people with adherence challenges.
Listen as they debate the potential risks and benefits of long-acting ART in this population, considerations for people with viremia or resistance, recommendations concerning proviral DNA genotyping, and how to interpret guidelines and provide truly patient-centered care.
Presenters
Aadia I. Rana, MD
Professor of Medicine
Division of Infectious Diseases
University of Alabama at Birmingham Heersink School of Medicine
Birmingham, AlabamaLaurence Slama, MD, PhD
Doctor
Department of Infectious Diseases
Hôtel Dieu University Hospital
University Paris Cité
Paris, FranceFollow along with the slides here.
See the full program here.
Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast channel on Apple Podcasts, Google Podcasts, or Spotify.
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In this episode, Gregory Huhn, MD, MPHTM, presents a case study of a person with a long HIV treatment history, exploring when and how to consider agents with novel mechanisms of action.
Listen as he discusses:
The importance of engaging with patients to understand their perspectives and improve their satisfaction with their HIV careOptions in people with multiclass resistanceStudies of agents with novel mechanisms of action:BRIGHTE (fostemsavir)TMB-301/-311 (ibalizumab)CAPELLA (lenacapavir)
Faculty
Gregory Huhn, MD, MPHTM,
Interim Chief, Division of Infectious Diseases
Senior Director of HIV Services
Cook County HIV Integrated Programs
Interim Medical Director, The RMR CORE Center
Professor, Division of Infectious Diseases
Rush University Medical Center
Chicago, IllinoisFollow along with the slides.
https://bit.ly/4fHmxg5Get access to all of our new podcast episodes. Subscribe to the CCO Infectious Disease podcast on Apple Podcasts, Google Podcasts, or Spotify.
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In this episode, Yvonne Gilleece, MB BCh, BAO, FRCP, uses a case study to illustrate why giving people space and time to engage in HIV care on their terms is key to overcoming potential shame and stigma.
She discusses how people can be very vulnerable when engaging in HIV care, and trauma-informed care can help address these vulnerabilities in a safe, respectful way. Listen as she gives her perspectives on:
Trauma-informed careOvercoming stigma and shameStaying in care
Presenter:
Yvonne Gilleece, MB BCh, BAO, FRCP
Honorary Clinical Professor and Consultant in HIV Medicine & Sexual Health
Brighton & Sussex Medical School and University Hospitals Sussex NHS Foundation Trust
Chair of the British HIV Association
Lead for HIV & Women
Lead for HIV & Hepatitis
Brighton, United KingdomContent based on an online CME program supported by an educational grant from Gilead Sciences, Inc.
Link to full program:
https://bit.ly/3xicSeFGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.
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