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What if we could target genetic diseases at their root, offering lifelong cures instead of temporary solutions?
And what role do statisticians play in making this breakthrough possible?
In this episode of The Effective Statistician, I dive into the fascinating world of gene therapy—an area packed with both promise and complexity.
I'm thrilled to finally cover this revolutionary field with two expert guests, Avery McIntosh from Pfizer and Alex Sverdlov from Novartis. Together, we break down the science behind gene therapies, explore the ethical and logistical challenges, and reveal how statisticians drive these life-changing treatments forward.
So, how close are we to curing diseases through gene therapy? Let’s jump in and find out. -
What does it take to create an effective clinical development plan? How do our early decisions shape the path of a compound through clinical phases? And how can statisticians actively balance the demands of science, speed, and cost in drug development?
In this special 400th episode of The Effective Statistician, I dive into these questions with Carrie Li, a biostatistics expert whose career spans both big pharma and startups. Carrie shares how she builds clinical development plans from scratch, collaborates with cross-functional teams, and uses statistical expertise to create strategies that drive both scientific and commercial success.
Join us as we explore the impact statisticians have on the clinical development journey. -
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Have you wondered how large language models (LLMs) like ChatGPT are transforming the way we work?
How can AI tools boost efficiency in statistics and pharmaceutical research?
In this episode of The Effective Statistician, I talk with Pietro Mascheroni from Boehringer Ingelheim to answer these questions. Pietro, a physicist, shares how LLMs are being used in real-world applications, from simplifying document retrieval to enhancing data exploration and refining code.
We dive into why it’s crucial to maintain human oversight, how AI can improve team communication, and the challenges in validating these models.
If you're eager to learn how AI can revolutionize your work or help you stay ahead in this fast-paced field, tune in to this insightful episode! -
Are you a statistician looking to expand your career beyond the statistics department?
Do you want to know how your data expertise and strategic thinking can open new doors?
In this episode of The Effective Statistician podcast, I sit down with Swarna Khare, who made that leap and found success in strategic roles across the industry. We explore her journey, discussing how statisticians can leverage their skills to create a bigger impact outside of technical roles.
If you're ready to take your career to the next level, this episode is packed with actionable insights to help you step beyond the statistics function and into new opportunities. -
Are you trying to boost your productivity and organize your tasks more efficiently?
In this episode of The Effective Statistician, I talk with Taina Pereenniemi about how Notion can help you take control of your workflows. Taina shares how she transformed her own productivity by using Notion to manage tasks, projects, and collaboration all in one place.
We dive into how you can start using Notion right away to simplify your work and personal life.
Plus, get a preview of Taina’s upcoming workshop at the Effective Statistician conference, where she'll guide participants through setting up their own Notion systems. -
What can statisticians gain from the world of software engineering?
How can coding practices from companies like Google help us enhance the quality of statistical work in the pharmaceutical industry?
In this episode of The Effective Statistician, I talk with Daniel Sabanés Bové to explore these questions. Daniel walks us through his career, from working as a biostatistician at Roche to becoming a data scientist at Google, and shares why he returned to healthcare. We discuss how applying software engineering principles—like clean coding, automation, and collaboration—can transform the way statisticians work.
If you want to improve your coding skills and efficiency using open-source tools and better workflows, this conversation with Daniel offers practical insights and a glimpse into his new consulting venture, RCONIS. -
Are you curious about how predictive models forecast future outcomes?
Or how do experts build and test these models to ensure they’re reliable?
In this episode, I sit down with Chantelle to explore these questions and dive deep into the world of predictive modeling. We break down the process, from analyzing the data to validating the final model, and discuss how these techniques are used, especially in healthcare.
If you're eager to understand how predictive models work and why they matter, this episode is for you. -
How can artificial intelligence simplify your daily work?
How do tools like GitHub Copilot streamline tasks for statisticians and data scientists?
In this episode of The Effective Statistician, I explore these questions with Paolo Eusebi, who shares his direct experience using Copilot in R Studio. We dive into how AI can suggest accurate code, assist with data manipulation, and help you quickly learn new programming techniques. We also discuss the critical need to safeguard data privacy when using these tools in larger organizations.
Join us to see how AI can boost your productivity and transform how you work! -
Are you feeling nervous about delivering your next presentation? Do you dread the moment you step in front of an audience? You’re not alone.
But what if you could turn that anxiety into confidence and deliver your presentation like a pro? In this episode, I guide you through practical tips to help you feel more comfortable and in control. You’ll learn how to shift your focus to the audience, practice to build confidence and master your setup, whether in-person or virtual. I also show you how to use your voice effectively, incorporate gestures, and even film yourself to identify areas for improvement. Ready to transform your presentation skills? Let’s get started! -
In this episode, I dive into some key questions:
How does luck influence our careers?
How do we stay humble while continually learning and growing?
What can we learn from someone who has shaped the field of statistics for decades?
I’m thrilled to explore these topics with one of the most influential statisticians, Stephen Senn. Stephen shares his journey, revealing the pivotal decisions that guided his career and the insights he gained along the way.
Join me as we uncover the lessons that can inspire and guide statisticians at every stage of their careers. -
Do your slides overwhelm your audience with too much information?
Are they cluttered, and distracting from the message you want to deliver?
In this episode, I help you tackle these challenges by showing you how to craft better, more engaging slides. Building on the last two episodes about preparing presentations, I guide you through practical strategies to simplify your slides, focus on key takeaways, and enhance them with visuals and storytelling.
With these tips, you’ll create slides that captivate your audience and strengthen your overall presentation. -
Are you curious about how artificial intelligence is transforming clinical research?
Do you want to know how statisticians can use AI to improve healthcare outcomes?
In this episode, I explore these questions with Francois Vandenhende, a seasoned expert in the pharmaceutical industry with nearly three decades of experience. Francois shares his journey from using traditional statistical methods to pioneering AI and machine learning in clinical development. We dive into how AI is making a difference in areas like digital twins and the integration of structured and unstructured data. Francois also highlights how statisticians can leverage AI to shape the future of healthcare.
Join us as we uncover the exciting opportunities AI offers in clinical research and why it’s more than just a trend. -
Do you ever wonder what makes a presentation truly resonate with your audience?
What turns a simple delivery into something unforgettable?
In this episode, I tackle these questions head-on by exploring three key areas that every presenter must address: ethos, logos, and pathos. These timeless concepts, rooted in Greek philosophy, still hold incredible power today.
By mastering them, you can boost your credibility, sharpen your message, and forge a stronger emotional connection with your audience.
Join me as I reveal how these strategies can elevate your presentations and enhance your influence as a statistician. -
Have you ever questioned how biostatistics and IT intersect, or why managing this relationship can feel so challenging?
In this episode, I sit down with Pablo Joerger, a statistician who transitioned into programming after over 40 years in the pharmaceutical industry. We explore how the shift from mainframes to cloud computing has revolutionized our field and examine the pivotal role IT plays in supporting modern statistical analyses.
If you're looking to better understand or improve your work at the intersection of biostatistics and IT, this episode offers practical insights and valuable takeaways. -
Are you ready to elevate your presentation skills?
Do you know the key steps to create a presentation that drives action?
What if a few simple questions could drastically improve your presentation outcomes?
In this episode, I guide you through the five essential questions that will help you create presentations that do more than just inform—they inspire action.
Whether you're aiming to influence decision-makers, communicate complex study designs, or share ideas effectively, mastering these fundamentals will make all the difference in your communication strategy. Join me as we explore how to make every presentation count. -
Today, we’re diving into some intriguing questions:
How can big pharmaceutical companies and small providers work together more effectively?
What hidden costs and inefficiencies are lurking in traditional outsourcing models?
And how can innovative solutions transform these dynamics?
I'm joined by Sheila Mahoney, a seasoned drug development expert with over 25 years of experience. Sheila introduces us to LifeSciHub, a platform designed to streamline contracting processes and enhance collaboration.
Together, we explore how LifeSciHub's approach not only improves cost-effectiveness but also ensures access to top-tier expertise.
Join us as we uncover new ways to optimize pharma collaborations for better outcomes. -
In this exciting continuation of our series on digital transformation and innovation, we dive deeper into the crucial role of policies in driving successful change.
I’m joined once again by Chris Colangelo, who brings his extensive experience from working closely with IT and digital teams.
In this episode, we examine how companies often overlook strategic policies and the implications of build versus buy decisions. Chris shares his insights on aligning technology strategies with business objectives and navigating the complexities of organizational change.
Join us as we explore these essential aspects and provide actionable advice to help you lead effective digital transformation in your organization.
Here is Part 1 of this series:
https://theeffectivestatistician.com/digital-transformation-and-innovation-part-1/ -
Have you ever wondered why some digital transformation efforts fail miserably while others succeed brilliantly?
Are you curious about the key elements that can make or break innovation in your organization?
Today, I explore these questions with my former colleague and friend, Chris Colangelo. With extensive experience in digital transformation at Eli Lilly and Pfizer, Chris now leads his own consultancy, Colangelo Advisory Group.
In this episode, we uncover the critical mistakes to avoid and the strategies to embrace for successful innovation and transformation. From understanding the importance of mindset and managing emotions to navigating policies and effective communication, Chris shares invaluable insights for statisticians looking to drive meaningful change.
Let’s dive in and discover how to turn digital transformation challenges into opportunities! -
Have you ever wondered how coaching can impact your career and success?
Are you curious about the differences between coaching and mentoring and how each can benefit you?
In this episode, I explore these questions with Alun Bedding, a seasoned statistician who has recently ventured into the world of coaching. I'm thrilled to welcome Alun back to the show. He shares his inspiring journey from taking leadership courses to launching his own coaching business. We explore the value of having a coach, the transformative power of effective coaching practices, and practical advice for enhancing your professional skills.
Whether you want to gain new perspectives or unlock your potential, this episode offers valuable insights for statisticians and professionals alike. Join us as we uncover how coaching can propel you toward greater achievements. -
Are you curious about how benefit-risk assessments in healthcare evolve?
Do you wonder how patient preferences shape these evaluations?
Today, I speak with Tommi Tervonen, a leading expert in this field, to answer these questions and more. Tommi, the Chief Scientist at Kielo Research in Zurich, brings nearly two decades of experience in Multi-Criteria Decision Analysis (MCDA), patient preferences, and benefit-risk evaluations.
This episode sheds light on the past, present, and future of benefit-risk assessments and shows how incorporating patient input is transforming healthcare decisions. Join us as we dive deep into this fascinating topic and discover the importance of structured methodologies and patient-centric approaches in making informed healthcare choices. - もっと表示する
