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http://www.einstein.yu.edu - Jonathan Lai, Ph.D., and colleagues have engineered the first antibodies that can potentially neutralize the two deadliest strains of the virus that causes Ebola hemorrhagic fever. The findings were published online January 13 in the journal Scientific Reports. Dr. Lai, associate professor of biochemistry at Albert Einstein College of Medicine, and John Dye, Ph.D., branch chief of viral immunology at USAMRIID, were co-leaders on the study.
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http://www.einstein.yu.edu - New research on sickle cell disease by Paul Frenette, M.D., has found that using antibiotics to deplete the body’s microbiome may prevent acute sickle cell crisis and could offer the first effective strategy for warding off the disease’s long-term complications, such as organ failure. The findings were published online on September 16 in the journal Nature. Dr. Frenette is professor of medicine and of cell biology and chair and director of Gottesman Institute for Stem Cell and Regenerative Medicine Research at Albert Einstein College of Medicine.
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http://www.einstein.yu.edu - Results of a new survey of more than 1,000 U.S. adults has found that misperceptions about miscarriage and its causes are widespread. Results of the survey, conducted by Dr. Zev Williams show that guilt and shame are common and fewer than half of respondents say they received adequate emotional support from the medical community. The findings were published online on May 11 in the journal Obstetrics & Gynecology. Dr. Williams is director of the Program for Early and Recurrent Pregnancy Loss (PEARL) at Albert Einstein College of Medicine and Montefiore Health System and is assistant professor of obstetrics & gynecology and women’s health, and of genetics, at Einstein.
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http://www.einstein.yu.edu - Kartik Chandran, Ph.D., explains the novel strategies he and his colleagues are using to develop treatments for Ebola viral infections. Watch 3-D animations showing how Ebola enters a cell and delivers its payload in order to replicate and spread throughout the body. Dr. Chandran is associate professor of microbiology & immunology at Einstein. Major funding for this research is provided by the NIH, U.S. Defense Threat Reduction Agency, Chan Family Foundation, and Albert Einstein College of Medicine.
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http://www.einstein.yu.edu - With the help of animations, Betsy Herold, M.D. shows why some drugs that prevented HIV and herpes transmission in the lab failed to protect women in clinical trials. See how proteins in semen act as an “invisibility cloak” for HIV and herpes viruses allowing them to bypass drugs and infect cells. Using lab techniques informed by clinical results, Dr. Herold conducts translational research on the next generation of drugs to prevent HIV and HSV infection. She is professor of pediatrics and of microbiology and immunology at Albert Einstein College of Medicine and chief, division of pediatric infectious diseases at The Children’s Hospital at Montefiore.
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http://www.einstein.yu.edu - A new study by Dr. Sophie Molholm suggests that measuring how fast the brain responds to sights and sounds could help in objectively classifying people on the autism spectrum and may help diagnose the condition earlier. The paper was published today in the online edition of the Journal of Autism and Developmental Disabilities. Dr. Molholm is associate professor in the Dominick P. Purpura Department of Neuroscience and the Muriel and Harold Block Faculty Scholar in Mental Illness in the department of pediatrics at Albert Einstein College of Medicine. Read full press release:http://dev.einstein.yu.edu/news/releases/1041/brainwave-test-could-improve-autism-diagnosis-and-classification/
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http://www.einstein.yu.edu - Using animations and a walk through his lab, Dr. Steven Almo explains in lay terms why protein structure and shape are important in developing drugs to fight disease. See how proteins are turned into crystals, how X-ray crystallography works and how an immune cell’s ignition, accelerator and brakes can be manipulated to fight cancer or autoimmune disease. Dr. Almo is professor of biochemistry and Wollowick Family Foundation Chair in Multiple Sclerosis and Immunology at Albert Einstein College of Medicine. Learn more about Dr. Almo's research at: www.einstein.yu.edu/faculty/almo
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https://www.einstein.yu.edu - Dr. Joe Verghese has found that nearly 1 in 10 met criteria for pre-dementia based on a simple test that measures how fast people walk and whether they have cognitive complaints. People who test positive for pre-dementia were twice as likely as others to develop dementia within 12 years. The paper was published online on July 16 in Neurology. Dr. Verghese is professor in the Saul R. Korey Department of Neurology and medicine at Einstein, chief of geriatrics at Einstein and Montefiore, and senior author of the Neurology paper.
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https://www.einstein.yu.edu - Determined to find a treatment for children with the degenerative brain disease Niemann-Pick Type C, Steven Walkley, D.V.M., Ph.D., turned a serendipitous laboratory discovery into a successful national research collaboration with other academic institutions and the National Center for Advancing Translational Sciences' program for rare diseases (Therapeutics for Rare and Neglected Diseases). These efforts led to an NIH Phase 1 clinical trial testing cyclodextrin
as a therapy for children with this disease. Dr. Walkley is a professor in the Dominick P. Purpura Department of Neuroscience and director of the Rose F. Kennedy Intellectual and Developmental Disabilities Research Center at Albert Einstein College of Medicine. -
https://www.einstein.yu.edu/cerc - Pediatrician Lisa Shulman shows the motor milestones expected in typically developing babies, from head control to walking and what pediatricians look for during a well-baby visit. She also explains the specific types of motor control a baby must master before the next milestone can be achieved. Dr. Shulman is associate professor of clinical pediatrics at Albert Einstein College of Medicine and an attending physician in pediatrics at The Children's Hospital at Montefiore. She is also director of the RELATE program for the diagnosis and treatment of autism and related disorders at Einstein's Children's Evaluation and Rehabilitation (CERC).
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http://www.einstein.yu.edu - Researchers at Albert Einstein College of Medicine developed a mouse model in which molecules crucial to making memories (beta-actin mRNA) were given fluorescent "tags" so they could be tracked. This clip shows them traveling within a live brain cell in real time. Video Credit: Credit: Hye Yoon Park, Ph.D. Read news release: http://www.einstein.yu.edu/news/releases/968/watching-molecules-morph-into-memories/
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http:/www.einstein.yu.edu - The Western Diet -- defined by fried and sweet foods, processed and red meat, refined grains and high-fat dairy products -- has been liked to colon cancer. Leonard Augenlicht, Ph.D., explains his research into how diet impacts the colon and the development of the disease. Dr. Augenlicht is director of Einstein's Biology of Colon Cancer Program and a professor of medicine and of cell biology at Albert Einstein College of Medicine.
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http://www.einstein.yu.edu - Dr. Hannes Buelow has identified a gene that orchestrates the crucially important branching of nerve fibers that occurs during development. The findings were published online today in the journal Cell. Dr. Buelow is associate professor in the Dominick P. Purpura Department of Neuroscience and of genetics at Albert Einstein College of Medicine. See accompanying release: http://www.einstein.yu.edu/news/releases/941/previously-unstudied-gene-is-essential-for-normal-nerve-development/
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http://www.einstein.yu.edu - Dr. Jean Hébert has found that inner-ear dysfunction can directly cause neurological changes that increase hyperactivity. The paper was published online in the journal Science on September 5, 2013. Dr. Hébert is professor in the Dominick P. Purpura Department of Neuroscience and of genetics at Albert Einstein College of Medicine. See accompanying release: http://www.einstein.yu.edu/news/releases/932/inner-ear-disorders-may-cause-hyperactivity/
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http://www.einstein.yu.edu - John Foxe, Ph.D. shows how his lab measures multisensory integration in high-functioning children with autism spectrum disorder (ASD). He found that younger children with ASD have trouble integrating the auditory and visual cues while listening to speech, but that the problem clears up in adolescence. Dr. Foxe is director of research at Albert Einstein College of Medicine's Children's Evaluation and Rehabilitation Center and professor of pediatrics and of neuroscience.
Watch video about the study: http://youtu.be/iES0xGDqbQc
See the press release: http://www.einstein.yu.edu/news/releases/931/autistic-children-can-outgrow-difficulty-understanding-visual-cues-and-sounds/ -
http://www.einstein.yu.edu - Dr. John Foxe has shown that high-functioning autism spectrum disorder (ASD) children appear to outgrow a critical social communication disability. The paper was published online August 28, 2013, in Cerebral Cortex. Dr. Foxe is professor of pediatrics and in the Dominick P. Purpura Department of Neuroscience, as well as director of research of the Children's Evaluation and Rehabilitation Center at Albert Einstein College of Medicine. See accompanying release: http://www.einstein.yu.edu/news/releases/931/autistic-children-can-outgrow-difficulty-understanding-visual-cues-and-sounds/
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http://www.einstein.yu.edu - Researchers Drs. Yvette Calderon, Jason Leider and Ethan Cowan have found that community-based pharmacies can be effective locations for offering rapid HIV testing, diagnosing HIV, and connecting those who test positive with medical care quickly. Their paper published in the August 2013 edition of AIDS Patient Care and STDs. See accompanying release: http://www.einstein.yu.edu/news/releases/928/community-pharmacies-are-effective-locations-for-rapid-hiv-testing/
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Dr. Paul Frenette has found that nerves play a critical role in both the development and spread of prostate tumors. The paper was published online July 12, 2013, in Science. Dr. Frenette is professor of medicine and of cell biology and director of the Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research at Albert Einstein College of Medicine. See accompanying release: http://www.einstein.yu.edu/news/releases/922/nerves-play-key-role-in-triggering-prostate-cancer-and-influencing-its-spread/
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May 21, 2013 - Dr. William Jacobs, Jr., has determined that vitamin C kills drug-resistant tuberculosis bacteria in laboratory culture. The paper was published online May 21, in Nature Communications. Dr. Jacobs is professor of microbiology & immunology and of genetics at Einstein. Dr. Jacobs is also a Howard Hughes Medical Institute investigator. See accompanying release: http://www.einstein.yu.edu/news/releases/907/study-finds-vitamin-c-can-kill-drug-resistant-tb/
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March 3, 2013 - Dr. Ana Maria Cuervo has discovered why toxic clumps of proteins accumulate in brain cells of those with a familial form of Parkinson's disease. The paper was published online March 3 in Nature Neuroscience. Dr. Cuervo is professor of developmental & molecular biology and the Robert and Renee Belfer Chair for the Study of Neurodegenerative Diseases at Albert Einstein College of Medicine. See accompanying release:http://www.einstein.yu.edu/news/releases/875/scientists-identify-clean-up-snafu-that-kills-brain-cells-in-parkinsons-disease/
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