Episoder
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In this compelling episode of The Alpha Human Podcast, host Lawrence Rosenberg welcomes Dakota Meyer—United States Marine, scout sniper, the second-youngest living Medal of Honor recipient, and author of three transformative books: Into the Fire: A Firsthand Account of the Most Extraordinary Battle in the Afghan War, The Way Forward: Master Life’s Toughest Battles and Create Your Lasting Legacy, and his latest, Why to What: The One-Word Answer to Taking Back Control of Your Life, which we explore in depth.
In their conversation, Dakota underscores the transformative power of shifting from problem-based "why" questions and unproductive rumination to solution-focused "what" questions, empowering individuals to take actionable control of life's challenges. He also delves into the skill of categorizing obstacles as inconveniences, problems, or emergencies, providing a practical framework for mastering the management of emotional energy.
We also explore Dakota's groundbreaking "Box Method," a powerful tool for identifying core values and aligning decisions and actions to create a life of purpose. Complementing this, he introduces the "Dash Method," a dynamic approach that underscores the role of decisions, actions, support systems, and habits in shaping a lasting legacy.
Additionally, Dakota emphasizes the profound impact of intentionality in everyday actions, relationships, and goals, offering a fresh perspective on support—not just through people, but also through the places and things that influence mindset and productivity. His practical strategies for breaking unproductive habits and cultivating new ones aligned with personal values offer an inspiring roadmap for meaningful growth.
Dakota's candid reflections, practical advice, and unfiltered honesty offer a blueprint for overcoming adversity and achieving meaningful growth.
Links:
https://dakotameyer.com/
https://dashstrategies.com/
Instagra: @dakotameyer0317 -
In this episode of The Alpha Human Podcast, host Lawrence Rosenberg interviews retired Navy SEAL Mark Green, delving into his impressive 20-year career in the SEAL Teams. Mark shares insights from his journey as an elite SEAL sniper, sniper instructor, and officer, leading deployments in Iraq and Afghanistan.
The conversation covers Mark's mindset during high-stakes missions, the relentless pursuit of mastery in the SEAL sniper program, and the distinct mental discipline required to operate in chaotic environments. Mark discusses how SEAL training taught him to break overwhelming challenges into manageable parts, a skill that among other things, helped him through some of the darkest moments of his transition back to civilian life, an often overlooked and challenging phase for veterans.
After retiring, Mark dedicated himself to helping veterans by joining the University of Southern California to support veteran programs, and by writing his new book, Unsealed: A Navy SEAL’s Guide to Mastering Life’s Transitions. The book aims to provide a roadmap for veterans, their families, and civilians navigating life changes, offering valuable lessons in resilience, leadership, and vulnerability.
This episode is a powerful exploration of what it means to persevere, adapt, and redefine purpose beyond the battlefield, making it essential listening for anyone interested in personal growth, high-performance mindset, or understanding the often-hidden struggles veterans face when they return home.
Links:
Mark's website: https://www.themarkgreene.com/
Mark's book on Amazon "Unsealed: A Navy Seal's Guide to Mastering Life's Transitions": https://a.co/d/cht58h4
Mark Greene on Instagram: https://www.instagram.com/themarkgreene -
Mangler du episoder?
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In this episode of the Alpha Human Podcast, host Lawrence Rosenberg engages in a compelling conversation with retired U.S. Army Green Beret Lieutenant Colonel Scott Mann. Beyond his 23-year military career in combat operations across Colombia, Iraq, and Afghanistan, he is an accomplished playwright and actor who created the stage play "Last Out: Elegy of a Green Beret," shedding light on veterans' untold stories and the profound cost of war on military families.
He's also the bestselling author of "Operation Pineapple Express," which details a grassroots mission to rescue Afghan elite forces allies during the chaotic withdrawal from Afghanistan. In addition, Scott founded Rooftop Leadership to train corporate leaders, law enforcement, and military teams, as well as The Heroes Journey, a nonprofit helping veterans and first responders find their voice as they transition to civilian life.
During their conversation, Lawrence and Scott explore Scott's new book "Nobody Is Coming to Save You: A Green Beret's Guide to Getting Big Sh*t Done." They delve into the importance of connection and rapport by understanding the human operating system, that humans are meaning-seeking, emotional, and social storytellers who struggle.
They also delve into "the churn" as a modern challenge, a metaphor for the forces that divide and isolate people, eroding trust and fueling fear and anger. Scott shares insights on how to find meaning and purpose through "leaving tracks," and how to use storytelling and narrative competence (the ability to influence and inspire others), as potent leadership tools that help ensure we get big things done.
Links:
https://scottmann.com/
https://scottmann.com/patreon/
https://rooftopleadership.com/ -
In this episode of the Alpha Human Podcast, host Lawrence Rosenberg sits down with Nick Lavery, an extraordinary Green Beret who truly embodies the term 'unstoppable.'
In their discussion, Nick, who made history as the first above-knee amputee to return to full combat operations in Special Forces, delves into his book 'Objective Secure' and his powerful achievement oriented philosophy, highlighting the importance of having a true perspective on the ephemeral nature of time, brutal self-honesty, and the careful use of language to shape one's reality and push beyond perceived limits.
Nick also explores the 3 essential questions to finding one's purpose, the often overlooked but very real concept of the 'fear of success,' and the costs of following one's ambition. The conversation is also rich with practical advice on navigating the grind, overcoming the monotony that can derail even the most passionate pursuits, and maintaining discipline when motivation wanes.
This episode is a must-listen for anyone seeking to break through their perceived limits to achieve the extraordinary.
Links:
Team Machine: https://teammchn.com/
Nick's YouTube Chanel: @NickMACHINELavery -
In this episode of the Alpha Human Podcast, Lawrence Rosenberg welcomes Jeff Struecker, a distinguished US Army Ranger and member of the Ranger Hall of Fame, who served in 17 combat deployments across five US wars, including the infamous Battle of Mogadishu, which was memorialized in the film Black Hawk Down.
The discussion explores how Jeff overcame the fear of certain death while leading his squad through intense enemy fire in the chaotic streets of Mogadishu, Somalia. Additionally, the conversation delves into 'the war within'—the internal struggle to align one's life with spiritual convictions, and key lessons from his book "Start Here," emphasizing the importance of never outgrowing the Gospel, understanding the cost of following Christ, and the '4-lane bridge' to the Kingdom of God.
Links:
https://jeffstruecker.com/
http://unbeatablearmy.com/
https://www.instagram.com/jeffstruecker/
https://www.youtube.com/@jeff_struecker -
Disclaimer: The content of this podcast, and any information, advice, opinions or statements within it are not intended, and are not to be used as a substitute for professional medical advice, diagnosis, or treatment. You should not disregard or delay in obtaining medical advice for any medical condition you may have, and you should seek the assistance of a healthcare professional for any such conditions, and always inform your doctor of any changes you make, or are thinking about making to your lifestyle.
In this episode of the Alpha Human Podcast, Lawrence Rosenberg welcomes back Jay Feldman from the Energy Balance Podcast to discuss the benefits of a high-carbohydrate diet on autoimmune conditions and liver health. Lawrence also shares his remarkable transformation after applying Jay's recommendations, noting a dramatic improvement in his liver health, liver enzymes, and resolution of a brief appearance of fatty liver.
Additionally, Jay and Lawrence delve into scientific studies linking high sugar intake to inflammation and autoimmune disease and why a high-carb, bioenergetic approach is more effective and healthier in the long run for managing inflammatory conditions, autoimmune diseases, and non-alcoholic fatty liver disease (NAFLD).
Their discussion underscores the importance of re-evaluating ketogenic, low-carb dietary choices and considering the broader implications of these nutritional strategies, highlighting the potential benefits of a well-balanced, high-carbohydrate diet for long-term health.
Links:
Jay's Website: https://jayfeldmanwellness.com/
The Energy Balance Podcast: https://www.youtube.com/@JFwellness
www.alphahuman.org
Studies mentioned in the episode:
How sugar promotes inflammation: https://www.sciencedaily.com/releases/2022/03/220322122836.htm
Dietary sugar lowers immunity and microbiota that protect against metabolic disease: https://www.cell.com/cell-metabolism/fulltext/S1550-4131(22)00396-5
Ketogenic diet alleviates colitis by reduction of colonic group 3 innate lymphoid cells through altering gut microbiome: https://www.nature.com/articles/s41392-021-00549-9
An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans: https://www.cell.com/cell-metabolism/fulltext/S1550-4131(18)30054-8
Short-term weight loss and hepatic triglyceride reduction: evidence of a metabolic advantage with dietary carbohydrate restriction: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076656/
Emerging Role of Hepatic Ketogenesis in Fatty Liver Disease: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289363 -
On this episode of The Alpha Human Podcast, host Lawrence Rosenberg talks with Sgt. Charlie Eipper, a former U.S. Army helicopter pilot with over 30 years of front-line law enforcement experience. Sgt. Eipper spent 16 years as a member of the Wichita Falls, Texas SWAT team, gaining extensive experience as a SWAT sniper and serving as the head of the department’s Gang Task Force Unit. Throughout the conversation, Sgt. Eipper delves into the qualities and traits essential for excelling in the complex and demanding role of a sniper in law enforcement, as well as the profound psychological challenges that can arise following deadly encounters, offering a glimpse into the mental and emotional landscape that police and soldiers must navigate when using lethal force.
Sgt. Eipper also shares his insights on the intersection of faith and duty as outlined in his book, "Jesus Christ on Killing," and explores the scriptural interpretations of taking a life, examining various biblical passages to understand what the bible articulates about the morality and ethics of killing, and how scripture provides a framework for understanding the morality and legality of lethal force, emphasizing the conditions under which such actions are considered permissible by God. This discussion reflects on the biblical narratives and commandments that discuss the sanctity of innocent lives while also acknowledging the realities of justice and protection that sometimes necessitate and justify taking a life under certain circumstances, such as self-defense, war, and capital punishment.
Additionally, Sgt. Eipper addresses the fundamental misunderstanding of Christ's role as the Lamb of God and His commandment to "turn the other cheek," challenging the belief that Jesus is a pacifist. He provides a compelling case for the notion that Jesus will actually return as a "Man of War."
Links:
https://www.facebook.com/jesuschristonkilling
https://www.amazon.com/Jesus-Christ-Killing-Charlie-Eipper/dp/1628716096 -
In this episode of the Alpha Human Podcast, Lawrence Rosenberg talks with Jay Feldman, host of The Energy Balance Podcast, who offers a deep dive into the bioenergetic perspective on health, challenging prevailing dietary paradigms, particularly the skepticism around high-carbohydrate diets and the necessity of carbohydrates. Feldman methodically deconstructs the myths that carbohydrates are non-essential and that our ancestors had limited access to them, presenting evidence that ancient diets were likely rich in carbohydrates, which are crucial for optimal metabolic health and energy production.
Feldman also tackles the misconceptions about sugar and fructose, providing a nuanced explanation of their metabolic effects and disputing the common belief that sugars are inherently harmful. He emphasizes the body's ability to utilize carbohydrates efficiently, arguing against the notion that high carbohydrate intake inevitably leads to insulin resistance or metabolic disorders.
Additionally, the conversation explores the metabolic implications of low-carb and ketogenic diets, underscoring the bioenergetic view that carbohydrates are the body's preferred energy source. Feldman argues that this preference is not just about survival but about thriving, with optimal energy production and metabolic health being the key benefits.
Links:
Jay's Website: https://jayfeldmanwellness.com/
The Energy Balance Podcast: https://www.youtube.com/@JFwellness
www.alphahuman.org
Studies/Articles:
In Defense of Low Fat: A Call for Some Evolution of Thought:
https://deniseminger.com/2015/10/06/in-defense-of-low-fat-a-call-for-some-evolution-of-thought-part-1/
Neanderthals carb loaded, helping grow their big brains:
https://www.science.org/content/article/neanderthals-carb-loaded-helping-grow-their-big-brains
Humans were apex predators for two million years:
https://phys.org/news/2021-04-humans-apex-predators-million-years.html -
In this episode of the Alpha Human Podcast, host Lawrence Rosenberg talks with Bill Rapier, a former Navy SEAL who spent 14 years as an elite operator with the Naval Special Warfare Development Group (DEVGRU) and who is now dedicated to leveraging his vast experience in special operations to train civilians in self-defense through AMTAC Shooting and AMTAC Blades.
In this compelling discussion, Bill shares profound insights into how his Christian faith intertwines with his professional ethos, specifically as it pertains to teaching life-preserving skills in potentially lethal scenarios. He opens up about reconciling the use of force with his spiritual beliefs, offering a nuanced perspective on serving in combat roles while maintaining a strong moral compass. His reflections provide a deeper understanding of the interplay between duty, faith, and the ethical considerations of self-defense and combat.
The podcast also explores Bill's approach to personal development, highlighting the significance of physical fitness, mindset, and spiritual alignment in effectively handling violent confrontations. He advocates for a holistic training philosophy that encompasses not just tactical skills but also the cultivation of mental and spiritual resilience.
Links:
https://amtacblades.com
https://www.amtacshooting.com/
https://www.youtube.com/@amtacshooting
https://www.instagram.com/amtacshooting
https://www.instagram.com/amtacblades -
In this episode of the Alpha Human Podcast, Lawrence Rosenberg talks with Jeff Tiegs, a distinguished combat veteran with over 25 years of experience across elite units within U.S. Special Operations. Tiegs's military journey took him from serving as an Army Ranger and Green Beret to leadership roles as an assault force commander and Lieutenant Colonel within the storied ranks of Delta Force, otherwise known as "The Unit," where his contributions were pivotal in combat operations across Panama, Iraq, and Afghanistan.
Transitioning from the battlefield, Tiegs now directs his expertise toward a different fight - combating sex trafficking through his nonprofit initiative, Skull Games, which takes a groundbreaking approach to bringing predators to justice and delivering freedom to innocent women and children.
Jeff is also the author of "Where Have All the Heroes Gone?: A Pilgrimage Through the Bible, the Battlefield, and Back Home Again," an impactful autobiography that interlaces his experiences with the U.S. Army Special Forces alongside pivotal stories from the bible and his spiritual journey, enriched with compelling insights into the lives of biblical figures such as King David and Jesus Christ.
Throughout the podcast, Jeff reflects on the nuances of leadership, the moral complexities of combat, and the transformational power of Christian faith and duty. His story is a testament to the resilience of the human spirit, the importance of a purpose-driven life, and the continuous quest for redemption and service beyond the uniform. -
Disclaimer: The content of this podcast, and any information, advice, opinions or statements within it are not intended, and are not to be used as a substitute for professional medical advice, diagnosis, or treatment. You should not disregard or delay in obtaining medical advice for any medical condition you may have, and you should seek the assistance of a healthcare professional for any such conditions, and always inform your doctor of any changes you make, or are thinking about making to your lifestyle.
In this episode of the Alpha Human Podcast, Lawrence Rosenberg talks with Dr. AbulKalam M. Shamsuddin, a trailblazer in the field of cancer prevention and early detection. His distinguished career spans 43 years as a professor of pathology at the University of Maryland and includes his role as a senior scientist at the National Cancer Institute.
Dr. Shamsuddin has made notable contributions to cancer research, authoring over 100 scientific papers on cancer detection and prevention, particularly as it pertains to his groundbreaking findings on IP6 (inositol hexaphosphate), a natural anti-cancer compound whose development and commercialization he pioneered.
Dr. Shamsuddin is also the inventor of a rapid cancer test that can identify up to 90% of cancers and precancerous lesions, making it a significant advancement in the early detection of cancer. This technology is the core of cancer diagnostics company OncoVue’s screening technology, where D. Shamsuddin is the Co-Founder & Chief Scientific Officer.
In this episode of the podcast, Dr. Shamsuddin delves into the discovery of IP6 as a broad-spectrum anti-cancer compound, as well as its effectiveness in various conditions such as osteoporosis, kidney stones, autoimmune diseases, and diabetes.
Links:
Dr. Shamsuddin's IP-6 Research site:
http://ip-6.net
Dr. Shamsuddin's IP-6 Facebook group:
https://www.facebook.com/profile.php?id=100062344197196
Dr. Shamsuddin's revolutionary cancer screening test for rapid detection of cancer in its earliest stages:
https://www.oncovue.health/
Dr. Shamsuddin's book on IP6:
'IP6: Nature's Revolutionary Cancer Fighter'
https://www.amazon.com/IP6-Revolutionary-Cancer-Fighter-Shamsuddin-Abulkalam/dp/B015QL2WW6
Dr. Kim Vanderlinden & Dr. Ivana Vucenik's book on IP6:
'Too Good to Be True? Inositol + Cal Mag IP6'
http://www.ip-6.net/files/77513690.pdf
Inositol hexaphosphate (IP6) inhibits key events of cancer metastasis
https://pubmed.ncbi.nlm.nih.gov/14666663/
Inositol hexaphosphate plus inositol induced complete remission in stage IV melanoma: a case report
https://pubmed.ncbi.nlm.nih.gov/30615010/
Inositol Hexaphosphate (IP6): A Novel Treatment for Pancreatic Cancer
https://www.journalofsurgicalresearch.com/article/S0022-4804(05)00057-0/fulltext
Prostate Cancer and Inositol Hexaphosphate: Efficacy and Mechanisms
https://ar.iiarjournals.org/content/anticanres/25/4/2891.full.pdf
Efficacy and Mechanisms
Protection Against Cancer by Dietary IP6 and Inositol
https://www.tandfonline.com/doi/abs/10.1207/s15327914nc5502_1
Cancer Inhibition by Inositol Hexaphosphate (IP6) and Inositol: From Laboratory to Clinic
https://www.sciencedirect.com/science/article/pii/S002231662302535X
IP6 + Inositol: Nature's Medicine For The Millennium!: Discover How A Cocktail of Simple Molecules Can Prevent And Fight Cancer And Other Diseases by Prof AbulKalam M Shamsuddin MD PhD
https://www.amazon.com/IP6-Inositol-Medicine-Millennium-Molecules/dp/984332708X -
Disclaimer: The content of this podcast, and any information, advice, opinions or statements within it are not intended, and are not to be used as a substitute for professional medical advice, diagnosis, or treatment. You should not disregard or delay in obtaining medical advice for any medical condition you may have, and you should seek the assistance of a healthcare professional for any such conditions, and always inform your doctor of any changes you make, or are thinking about making to your lifestyle.
In this episode of The Alpha Human Podcast, Lawrence talks with renowned fitness expert Clark Bartram about his personal journey with prostate cancer. Clark's approach to the disease is unconventional, focusing on alternative treatments instead of traditional methods like surgery or radiation, with a battle plan that centers on four key objectives: slow the cancer, stop the cancer, destroy the cancer, and heal the root cause behind the cancer's occurrence.
Clark also shares his perspective on testosterone deprivation therapy, commonly used in prostate cancer treatment and emphasizes the importance of not letting your anxiety dictate your treatment path. He encourages those facing a similar diagnosis to take time to research, understand their condition, and make informed decisions rather than rushing into treatments out of fear.
Clark's story is a powerful reminder of the importance of self-advocacy and personalized care in the face of health challenges, and his experience offers valuable insights and inspiration for those facing prostate cancer.
Links:
Clark's CBX Men's Health Test Kit: clarkbartramsystems.com/products/mens-health-test-kit
Clark's YouTube Channel: www.youtube.com/@ClarkBartram
Clark's Personal Coaching: maximizedmanelite.com
instagram.com/clarkbartram
facebook.com/theclarkbartram
Supraphysiological Testosterone Therapy as Treatment for Castration-Resistant Prostate Cancer
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972313
This Gene Could Be the Link Between Iron and Prostate Cancer
https://www.futurity.org/iron-levels-prostate-cancer-1773212-2
Serum ferritin in combination with prostate-specific antigen improves predictive accuracy for prostate cancer
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392292
Inositol Hexaphosphate Inhibits Tumor Growth, Vascularity, and Metabolism in TRAMP Mice
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662486/ -
Disclaimer: The content of this podcast, and any information, advice, opinions or statements within it are not intended, and are not to be used as a substitute for professional medical advice, diagnosis, or treatment. You should not disregard or delay in obtaining medical advice for any medical condition you may have, and you should seek the assistance of a healthcare professional for any such conditions, and always inform your doctor of any changes you make, or are thinking about making to your lifestyle.
In this episode of The Alpha Human Podcast, Lawrence Rosenberg talks with Morley Robbins, founder of the Root Cause Protocol, on iron overload and its connection to cancer.
Robbins delves into the history and misconceptions surrounding iron and its perceived deficiency in human health leading to a societal fixation on iron supplementation. Robbins challenges this narrative, highlighting the abundance of iron in the environment and the human body's natural ability to regulate iron through copper.
Robbins asserts that many health issues, including cancer, are due to a lack of bioavailable copper and an excess of unregulated iron. He describes how the body's metabolism, particularly in cancer cells, shifts from using oxygen (oxidative phosphorylation) to fermenting sugar (glycolysis) due to a copper deficiency. This shift, known as the Warburg Effect, indicates a lack of bioavailable copper necessary for iron regulation and oxygen metabolism.
The conversation also touches on the role of liver impairment and non-alcoholic fatty liver disease, which Robbins attributes to an imbalance of copper, retinol, and iron. He emphasizes the importance of retinol (animal-based vitamin A) in maintaining copper balance and its critical role in overall health. Robbins challenges conventional wisdom on supplements like vitamin D and ascorbic acid, arguing that they can impede the body's natural mineral balance.
https://therootcauseprotocol.com/
"Copper deficiency will favor glycolysis and cell proliferation":
Role of Copper on Mitochondrial Function and Metabolism https://www.frontiersin.org/articles/10.3389/fmolb.2021.711227/full
The Disturbed Iron Phenotype of Tumor Cells and Macrophages in Renal Cell Carcinoma Influences Tumor Growth
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139531/
Altered Iron Metabolism and Impact in Cancer Biology, Metastasis, and Immunology
https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2020.00476/full
Copper deficiency increases iron absorption in the rat
https://journals.physiology.org/doi/full/10.1152/ajpgi.00509.2002
Association between blood copper and nonalcoholic fatty liver disease according to sex
https://www.sciencedirect.com/science/article/abs/pii/S0261561420304982 -
In this episode of The Alpha Human Podcast, Lawrence Rosenberg shares his experience with chromophobe kidney cancer and how taking control of his healing journey transformed his mindset, fostering hope and positivity. He delves into the concept of locus of control, discussing its psychological significance in recovery. He also explores studies demonstrating the mind-body connection's potential impact on healing via enhanced immune function, and the modulation of neurotransmitters, neuropeptides, hormones, and gene expression via epigenetics.
Lawrence also delves into the relationship between the mind's healing capabilities, emphasizing intention and visualization. He references two influential books: David Hamilton's "How Your Mind Can Heal Your Body" and Gerald Epstein's "Healing Visualizations: Creating Health Through Imagery." Hamilton discusses the critical role of visualization in the healing process and the significance of having a clear intent to guide imagination effectively. Epstein also emphasizes the importance of intention and how directing your will inward, allows for the conscious mastery of health. Lawrence goes further and adds that, when our intention and will is empowered by Jesus Christ, then anything becomes possible.
To that end, Lawrence explores Annette Capps' book "Quantum Faith," which draws parallels between quantum physics and Jesus Christ's teachings on faith and the spoken word. Lawrence illustrates how observation or intention can fundamentally alter the behavior of subatomic particles, emphasizing that reality may only manifest when observed or intended. This leads to a discussion of the power of intention and faith, referencing Bible verses underlining the impact of words and beliefs on reality.
Lawrence also discusses Kenneth Hagin's book, "Words," which underscores the significance of not only having faith but also professing and speaking one's beliefs and describes his daily routine of communion with Christ, visualizing healing through His light, energy, and spirit. He discusses the transformative impact of faith and the desire to honor and glorify Jesus Christ with his words and actions.
Links:
"Immune System and Psychological Changes in Metastatic Cancer Patients Using Relaxation and Guided Imagery": https://www.tandfonline.com/doi/abs/10.1080/16506078809455814
"Immune responses to guided imagery during breast cancer treatment": https://pubmed.ncbi.nlm.nih.gov/18077773/
"Rapid changes in histone deacetylases and inflammatory gene expression in expert meditators": https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039194/
"Is Oxytocin 'Nature's Medicine'?" https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7495339/
"Catecholamine levels in practitioners of the transcendental meditation technique": https://www.sciencedirect.com/science/article/abs/pii/S0031938400003863?via%3Dihub
"Daytime hormonal rhythms in practitioners of the transcendental meditation-Sidhi program": https://www.alliedacademies.org/articles/daytime-hormonal-rhythms-in-practitioners-of-the-transcendental-meditationsidhi-program.html
"Levels of immune cells in transcendental meditation practitioners": https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097901/
How Your Mind Can Heal Your Body by David Hamilton
https://shorturl.at/stvWY
Healing Visualizations: Creating Health Through Imagery by Gerald Epstein
https://shorturl.at/jmBDT
Quantum Faith by Annette Capps
https://shorturl.at/bIW04
God's Creative Power for Healing by Charles Capps
https://shorturl.at/ikl03
Words by Kenneth E. Hagin
https://shorturl.at/lxFM7 -
Disclaimer: The content of this podcast, and any information, advice, opinions or statements within it are not intended, and are not to be used as a substitute for professional medical advice, diagnosis, or treatment. You should not disregard or delay in obtaining medical advice for any medical condition you may have, and you should seek the assistance of a healthcare professional for any such conditions, and always inform your doctor of any changes you make, or are thinking about making to your lifestyle.
In this episode of the Alpha Human Podcast, Lawrence examines various interventional studies on the effects of dairy consumption on cancer progression and shares evidence suggesting that bovine milk, particularly its casein content, can lead to the metastasis of cancer. With that said, milk proteins have also been shown to possess anti-cancer properties as well and here we navigate this nuanced landscape, presenting both sides of the argument.
Intriguingly, and beyond the milk protein debate, Lawrence raises a far larger concern with respect to dairy and cancer, an issue starker than the conjecture surrounding casein protein, and that is the problems related to extracellular vesicles (EVs) derived from milk—a concern that could reshape the way we think about dairy consumption for individuals dealing with cancer.
The podcast explores a study that yielded unexpected results—while milk-derived EVs induced cellular senescence in cancer cells, reducing primary tumor size, they paradoxically accelerated cancer metastasis. This finding serves as a pivotal warning to those with cancer who might consider consuming dairy.
Lawrence's analysis of this critical revelation underscores the importance of carefully evaluating dietary choices, especially for individuals navigating cancer, and making informed decisions based on the available evidence.
Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis
https://www.nature.com/articles/s41467-021-24273-8
β-casein-derived peptides, produced by bacteria, stimulate cancer cell invasion and motility
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC275444/
Promotion of Aberrant Crypt Foci and Cancer in Rat Colon by Thermolyzed Protein
https://academic.oup.com/jnci/article-abstract/84/13/1026/985189
Milk Stimulates Growth of Prostate Cancer Cells in Culture
https://www.tandfonline.com/doi/full/10.1080/01635581.2011.609306
A Milk Protein, Casein, as a Proliferation Promoting Factor in Prostate Cancer Cells
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166373/
The milk protein α-casein functions as a tumor suppressor via activation of STAT1 signaling, effectively preventing breast cancer tumor growth and metastasis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507493/
Growth inhibitory effects of casein hydrolysates on human cancer cell lines
https://pubmed.ncbi.nlm.nih.gov/20053315/
Casein and Peptides Derived from Casein as Antileukaemic Agents
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754885/
The Therapeutic Potential of Milk Extracellular Vesicles on Colorectal Cancer
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224713/
Bovine milk-derived exosomes for drug delivery
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706492/
Camel Milk Modulates the Expression of Aryl Hydrocarbon Receptor-Regulated Genes, Cyp1a1, Nqo1, and Gsta1, in Murine hepatoma Hepa 1c1c7 Cells
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345340/ -
Disclaimer: The content of this podcast, and any information, advice, opinions or statements within it are not intended, and are not to be used as a substitute for professional medical advice, diagnosis, or treatment. You should not disregard or delay in obtaining medical advice for any medical condition you may have, and you should seek the assistance of a healthcare professional for any such conditions, and always inform your doctor of any changes you make, or are thinking about making to your lifestyle.
In this episode of the Alpha Human Podcast, Lawrence Rosenberg discusses the potential link between the consumption of peanuts and cancer metastasis. Peanuts contain peanut agglutinin (PNA), a lectin that binds to a complex sugar known as the T-antigen, a glycan bound to proteins found on certain cancer cells. This interaction mimics the actions of galectin-3, an endogenously produced human lectin (often overexpressed in cancer patients) that can bind to dysregulated glycoproteins on the membranes of cancer cells leading to enhanced cellular adhesion, invasion, migration, metastasis, angiogenesis, and immune evasion.
Additionally, PNA has been shown to interact with endothelial cells and trigger the secretion of metastasis-promoting cytokines that can lead to increased adhesion between tumor cells and blood vessel walls, facilitating tumor cell metastasis.
Lawrence also highlights modified citrus pectin (mCP), a natural compound that has been found to block galectin-3 activity and inhibit tumor growth. Additionally, mCP has shown promising results targeting multiple critical rate-limiting steps involved in cancer metastasis due to its anti-adhesive, apoptosis-promoting, and apoptosis-inducing properties.
Links:
'Peanut agglutinin appearance in the blood circulation after peanut ingestion mimics the action of endogenous galectin-3 to promote metastasis by interaction with cancer-associated MUC1'
https://academic.oup.com/carcin/article/35/12/2815/336118
'Appearance of peanut agglutinin in the blood circulation after peanut ingestion promotes endothelial secretion of metastasis-promoting cytokines'
https://academic.oup.com/carcin/article/42/8/1079/6315265
'Pectins from various sources inhibit galectin-3-related cardiac fibrosis'
https://www.sciencedirect.com/science/article/pii/S2452318621000477
Study: 'Modified citrus pectin stops progression of liver fibrosis by inhibiting galectin-3 and inducing apoptosis of stellate cells'
URL: https://cdnsciencepub.com/doi/10.1139/cjpp-2015-0284
Study: 'Modified citrus pectin inhibited bladder tumor growth through downregulation of galectin-3'
URL: https://www.nature.com/articles/s41401-018-0004-z
Study: 'Modified citrus pectin anti-metastatic properties: one bullet, multiple targets'
URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782490/ -
Disclaimer: The content of this podcast, and any information, advice, opinions or statements within it are not intended, and are not to be used as a substitute for professional medical advice, diagnosis, or treatment. You should not disregard or delay in obtaining medical advice for any medical condition you may have, and you should seek the assistance of a healthcare professional for any such conditions, and always inform your doctor of any changes you make, or are thinking about making to your lifestyle.
In this episode of The Alpha Human Podcast, Lawrence delves into the science behind several natural compounds that hold the power to combat cancer by triggering ferroptosis. These include:
Withaferin-A, isolated from the roots of Withania Somnifera (Ashwagandha), a traditional medicinal plant that has been found to induce ferroptosis and be significantly more potent than the standard chemotherapeutics Etoposide and Cisplatin in killing a set of high-risk neuroblastoma cell lines:
Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma
jci.org/articles/view/99032
Withania somnifera: from prevention to treatment of cancer
ncbi.nlm.nih.gov/pmc/articles/PMC4899165/
Berberine, a natural compound that appears to exhibit selective effects on ferroptosis (protecting healthy cells from the deadly effects of iron-mediated ROS while using these very same free radicals to induce cell death in cancer cells):
Berberine exerts its antineoplastic effects by reversing the Warburg effect via downregulation of the Akt/mTOR/GLUT1 signaling pathway
spandidos-publications.com/10.3892/or.2021.8204
Berberine inhibits erastin-induced ferroptosis of mouse hippocampal neuronal cells possibly by activating the Nrf2-HO-1/GPX4 pathway
pubmed.ncbi.nlm.nih.gov/35790446/
Berberine Induces Combined Cell Death in Gastrointestinal Cell Lines
mdpi.com/1422-0067/24/7/6588
Quercetin, a flavonoid that has been linked to the inhibition of multiple cancer types through various mechanisms also promotes ferroptosis via lysosomal activation:
Quercetin induces p53-independent cancer cell death through lysosome activation by the transcription factor EB and Reactive Oxygen Species-dependent ferroptosis
bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15350
Plumbago Zeylanica, known as Ceylon Leadwort, which demonstrates anticancer activity against multiple cancer cell lines through diverse mechanisms, has also been shown to induce ferroptosis in glioma cells:
Anticancer Effects and Mechanisms of Action of Plumbagin: Review of Research Advances
ncbi.nlm.nih.gov/pmc/articles/PMC7725562/
Targeting NQO1/GPX4-mediated ferroptosis by plumbagin suppresses in vitro and in vivo glioma growth
nature.com/articles/s41416-022-01800-y
Piperlongumine, an alkaloid extracted from the fruits and roots of Piper longum Linn, which exhibits anxiolytic, antiangiogenic, anti-metastatic, anti-tumoral, cytotoxic activity has also been found to induce Ferroptosis in pancreatic cancer cells:
The promising potential of piperlongumine as an emerging therapeutics for cancer
ncbi.nlm.nih.gov/pmc/articles/PMC9400693/
Piperlongumine, a potent anticancer phytotherapeutic: Perspectives on contemporary status and future possibilities as an anticancer agent
sciencedirect.com/science/article/abs/pii/S1043661820307830?via%3Dihub
Piperlongumine rapidly induces the death of human pancreatic cancer cells mainly through the induction of ferroptosis
spandidos-publications.com/10.3892/ijo.2018.4259
Curcumin, a natural compound found in turmeric, has been shown to induce ferroptosis in breast cancer cells and non-small-cell lung cancer cells:
Curcumin suppresses tumorigenesis by ferroptosis in breast cancer
bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15350
Curcumin induces ferroptosis in non-small-cell lung cancer via activating autophagy
onlinelibrary.wiley.com/doi/10.1111/1759-7714.13904 -
In this episode of The Alpha Human Podcast, Lawrence delves into drugs that can induce Ferroptosis, a form of cell death characterized by the accumulation of lipid peroxides and iron-dependent reactive oxygen species, as this might be an Achilles' heel for cancers that exhibit iron overload.
Although there are currently no approved drugs designed for this purpose, there are a number of existing pharmaceuticals that have demonstrated the ability to trigger ferroptosis in cancer cells.
For instance, Lawrence highlights Auranofin, a rheumatoid arthritis drug, and Metformin, a widely prescribed drug for diabetes that have both demonstrated the ability to induce ferroptotic death in cancer cells.
Additionally, Lawrence discusses the effectiveness of Artesunate, a derivative of artemisinin commonly prescribed as an anti-malarial drug, and Sulfasalazine, primarily used for treating inflammatory bowel diseases like ulcerative colitis, as both have shown the capability to trigger ferroptosis as well.
Targeting glutamine metabolism as a therapeutic strategy for cancer
nature.com/articles/s12276-023-00971-9
Auranofin mitigates systemic iron overload and induces ferroptosis via distinct mechanisms | Signal Transduction and Targeted Therapy
nature.com/articles/s41392-020-00253-0
Mechanisms of metformin inhibiting cancer invasion and migration:
ncbi.nlm.nih.gov/pmc/articles/PMC7540116/
Metformin may induce ferroptosis by inhibiting autophagy via lncRNA H19 in breast cancer
ncbi.nlm.nih.gov/pmc/articles/PMC8727937/
Iron plays a role in sulfasalazine-induced ferroptosis with autophagic flux blockage in K7M2 osteosarcoma cells
academic.oup.com/metallomics/article-abstract/14/5/mfac027/6571254
Sulfasalazine impacts on ferroptotic cell death and alleviates the tumor microenvironment and glioma-induced brain edema
oncotarget.com/article/8651/text/#F2
Sulfasalazine‑induced ferroptosis in breast cancer cells is reduced by the inhibitory effect of estrogen receptor on the transferrin receptor
spandidos-publications.com/or/42/2/826
Artesunate synergizes with sorafenib to induce ferroptosis in hepatocellular carcinoma
ncbi.nlm.nih.gov/pmc/articles/PMC8026986/#CR25
Identification of Artesunate as a specific activator of ferroptosis in pancreatic cancer cells
ncbi.nlm.nih.gov/pmc/articles/PMC4468338/
Artesunate induces ferroptosis via modulation of p38 and ERK signaling pathway in glioblastoma cells
sciencedirect.com/science/article/pii/S134786132200007X
Artesunate Inhibits the Growth Behavior of Docetaxel-Resistant Prostate Cancer Cells
frontiersin.org/articles/10.3389/fonc.2022.789284/full
Artesunate Inhibits Growth of Sunitinib-Resistant Renal Cell Carcinoma Cells through Cell Cycle Arrest and Induction of Ferroptosis
ncbi.nlm.nih.gov/pmc/articles/PMC7692972/
Disclaimer: The content of this podcast, and any information, advice, opinions or statements within it are not intended, and are not to be used as a substitute for professional medical advice, diagnosis, or treatment. You should not disregard or delay in obtaining medical advice for any medical condition you may have, and you should seek the assistance of a healthcare professional for any such conditions, and always inform your doctor of any changes you make, or are thinking about making to your lifestyle. -
In this episode of the Alpha Human Podcast, Lawrence Rosenberg dives into the fascinating connection between iron overload and cancer. Iron is an essential micronutrient that plays a crucial role in various biological processes, including energy production, DNA synthesis, and immune system function.
However, excess iron is also toxic and iron accumulation is typically seen in renal cell carcinoma (as well as other cancers), and increased iron metabolism is associated with the malignant transformation of cells, cancer progression, drug resistance, and immune evasion. In fact, individuals working in iron and steel occupations have a higher risk of developing kidney cancer.
With that said, Lawrence also introduces a recently discovered form of programmed cell death called ferroptosis, which is induced by elevated intracellular iron levels and subsequent depletion of the antioxidant glutathione. Ferroptosis represents a natural mechanism to eliminate cancer cells, as well as those cells deficient in key nutrients or damaged by infection or ambient stress. While ferroptosis is beneficial in removing problematic cells, it should also be noted that dysregulation or excessive activation can contribute to disease pathogenesis, including neurodegenerative disorders.
Interestingly, Lawrence highlights the unique characteristic of chromophobe renal cancer cells in having strikingly elevated levels of glutathione, which acts as a reactive oxygen species scavenger that protects these cells from ferroptosis. And although this metabolic dependency on glutathione enables chromophobe renal cell carcinoma (as well as a number of other cancers) to survive despite iron overload and oxidative stress, it may also turn out to be cancer's Achilles heal.
'Ferroptosis, a new form of cell death: opportunities and challenges in cancer':
https://jhoonline.biomedcentral.com/articles/10.1186/s13045-019-0720-y
'Study uncovers novel treatment for chromophobe renal cell carcinoma':
https://www.news-medical.net/news/20220620/Study-uncovers-novel-treatment
'Hypersensitivity to ferroptosis in chromophobe RCC is mediated by a glutathione metabolic dependency':
https://www.pnas.org/doi/10.1073/pnas.2122840119
'Metabolic reprogramming and elevation of glutathione in chromophobe renal cell carcinomas':
https://www.biorxiv.org/content/10.1101/649046v1.full
'The Disturbed Iron Phenotype of Tumor Cells and Macrophages in Renal Cell Carcinoma Influences Tumor Growth':
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139531/
'Altered Iron Metabolism and Impact in Cancer Biology, Metastasis, and Immunology':
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160331/
'Iron metabolism: State of the art in hypoxic cancer cell biology':
https://www.sciencedirect.com/science/article/pii/S0003986122000844
'Iron accumulation typifies renal cell carcinoma tumorigenesis but abates with pathological progression, sarcomatoid dedifferentiation, and metastasis':
https://www.frontiersin.org/articles/10.3389/fonc.2022.923043/full#B39
'Reactive Oxygen Species-Induced Lipid Peroxidation in Apoptosis, Autophagy, and Ferroptosis':
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815535/#B101
'The Two Faces of Reactive Oxygen Species in Cancer':
https://www.annualreviews.org/doi/abs/10.1146/annurev-cancerbio-041916-065808
Disclaimer: The content of this podcast, and any information, advice, opinions or statements within it are not intended, and are not to be used as a substitute for professional medical advice, diagnosis, or treatment. You should not disregard or delay in obtaining medical advice for any medical condition you may have, and you should seek the assistance of a healthcare professional for any such conditions, and always inform your doctor of any changes you make, or are thinking about making to your lifestyle. -
In this thought-provoking episode of the Alpha Human Podcast, Lawrence presents compelling insights from the medical and scientific literature that challenge the traditional theory of cancer as a disease driven by genetic mutations, introducing evidence that underwrites alternative explanations for how cancer develops. The episode also explores the causes of Chromophobe Renal Cell Carcinoma (ChRCC), the type of cancer Lawrence has been living with for the past seven years, delving into the influence of mitochondrial dysfunction, compensatory metabolic pathways, and cell-to-cell cannibalism.
Lawrence discusses significant findings from the scientific literature that could have a profound impact on ChRCC. While two of these findings were detailed in the previous episode and are particular to his case, the third explores insights from Thomas Seyfried, a renowned professor of biochemistry and genetics at Boston College that has implications for managing a broad spectrum of cancers.
Lawrence also continues to share his personal journey and the importance of understanding the causes of ChRCC and cancer in general, introducing alternative hypotheses that challenge the widely accepted somatic mutation theory (SMT) of cancer.
Lawrence discusses the tissue organization field theory (TOFT) as a substitute explanation for the development and progression of cancer and also explores Otto Warburg's theory of cancer as a mitochondrial metabolic disease. Lawrence cites research that supports ChRCC as a case study in line with Warburg's hypothesis, highlighting the role of mitochondrial dysfunction and the impact it has on epigenetic signaling.
Furthermore, Lawrence discusses the compensatory mechanisms employed by cancer cells to survive under adverse conditions, and how Thomas Seyfried's press-pulse strategy for managing cancer exploits this adaptive response, a method that may be a powerful alternative for dealing with cancer in a nontoxic manner, and the implications it has on the unexpected way ChRCC (and a few other cancers) obtain nutrients - which may present its own unique Achille's heal (or two).
Paradoxical Behavior of Oncogenes Undermines the Somatic Mutation Theory: www.ncbi.nlm.nih.gov/pmc/articles/PMC9138429/#B15-biomolecules-12-00662
Over a century of cancer research: Inconvenient truths and promising leads:
journals.plos.org/plosbiology/article?id=10.1371%2Fjournal.pbio.3000670
On the Origin of Cancer Cells: www.science.org/doi/10.1126/science.123.3191.309
The Prime Cause and Prevention of Cancer with two prefaces on prevention:
https://t.ly/7n66a
Impairment of gamma-glutamyl transferase 1 activity in the metabolic pathogenesis of chromophobe renal cell carcinoma: www.ncbi.nlm.nih.gov/pmc/articles/PMC6142242/
Press-pulse: a novel therapeutic strategy for the metabolic management of cancer: https://shorturl.at/fIOY4
Metabolic reprogramming and elevation of glutathione in chromophobe renal cell carcinomas:
www.biorxiv.org/content/10.1101/649046v1.full
Decreased Mitochondrial DNA Content Drives OXPHOS Dysregulation in Chromophobe Renal Cell Carcinoma:
https://t.ly/Q33FH
Endocytosis-Mediated Replenishment of Amino Acids Favors Cancer Cell Proliferation and Survival in Chromophobe Renal Cell Carcinoma: https://t.ly/i0oJL
Glutathione Metabolism in Renal Cell Carcinoma Progression and Implications for Therapies:
https://t.ly/eUsw9
Disclaimer: The content of this podcast, and any information, advice, opinions or statements within it are not intended, and are not to be used as a substitute for professional medical advice, diagnosis, or treatment. You should not disregard or delay in obtaining medical advice for any medical condition you may have, and you should seek the assistance of a healthcare professional for any such conditions, and always inform your doctor of any changes you make, or are thinking about making to your lifestyle. - Se mer
