Episoder
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In this episode of The Effective Statistician, I tackle a challenge that many of us face—working long hours and feeling stuck in an endless cycle of pressure and expectations.
I’ve spoken to countless professionals who struggle with ever-growing workloads, limited resources, and rigid workplace structures that make it difficult to work more efficiently. But the real issue isn’t just about managing tasks better—it’s about shifting the way we think about work.
Here, I break down the limiting beliefs that keep us trapped, like equating our value with how hard we work, mistaking busyness for productivity, and chasing perfection at the expense of progress. Join me as I share strategies to work smarter, achieve more, and create a healthier work-life balance.
Plus, I’ll tell you about an upcoming free webinar where I’ll dive even deeper into how you can become a more effective statistician while still enjoying life outside of work. -
In this episode of The Effective Statistician, I explore how GAMS—the General Algebraic Modeling System—can solve complex optimization problems and transform how you approach modeling.
I talk with Steve Dirkse, an expert who explains how GAMS simplifies challenges in logistics, healthcare, and beyond. Unlike generalized additive models, GAMS uses an algebraic modeling language to handle intricate systems with ease.
Together, we uncover how you can start using this powerful tool, access its resources, and apply it to real-world scenarios. Join me as we dive into this fascinating topic and uncover how GAMS can make a difference in your work! -
Mangler du episoder?
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Are you tired of rushing through endless meetings, juggling countless tasks, and feeling like the grind never stops?
Do you wonder if all this hustle is worth the toll it’s taking on your health, relationships, and happiness?
In this episode of The Effective Statistician, I challenge the unsustainable culture of constant hustle and offer a better path: long-haul leadership. I’ll show you how focusing on personal growth, prioritizing your well-being, and building meaningful connections can help you break free from the burnout cycle. Let’s explore how to create a career that’s not only impactful but also sustainable for the long run. -
Welcome to another episode of The Effective Statistician podcast!
Today, I tackle the essential skill of negotiation—a tool we statisticians use every day, often without realizing it. We negotiate when we push for better study designs, adjust project timelines, or secure resources like training and conference budgets. Beyond work, we negotiate in our personal lives with family, friends, or vendors.
In this episode, I share proven strategies to prepare for negotiations, uncover interests behind positions, and confidently advocate for yourself and your work.
Mastering these skills empowers you to drive success and create a bigger impact as a statistician. Let’s jump in! -
In this Friday edition of The Effective Statistician, Alun Bedding takes center stage to discuss a topic central to leadership and personal influence: Trust.
With his characteristic insight and practical approach, Alun explores how trust forms the foundation of effective leadership, regardless of one’s title or position. Drawing on real-world examples and actionable strategies, he highlights the habits and choices that help build trust, foster authenticity, and inspire those around us.
Whether you consider yourself a leader or not, this episode will challenge you to think differently about your role and influence. Tune in and discover how trust can transform your personal and professional life. -
Welcome to a brand-new year and an exciting new episode of The Effective Statistician!
I’m thrilled to kick off 2025 by sharing some incredible news—I’ve written a book! After years of planning, false starts, and a lot of learning along the way, How to Be an Effective Statistician is finally complete and will officially launch on January 15th. In this episode, I take you behind the scenes of how the book came to life. I’ll share why I wrote it, how it’s structured, and the practical insights it offers for statisticians, data scientists, and other quantitative professionals.
Whether you’re looking to improve communication, manage challenges, or simply be more effective in your role, this book was designed with you in mind. I’ll also give you all the details about the book launch party, where we’ll celebrate, learn, and connect.
Join me as I reflect on this journey and what it means for our community! -
In this Friday edition of The Effective Statistician podcast, Alun Bedding tackles the pervasive issue of imposter syndrome. He shares his own experiences with self-doubt, offering listeners a transparent and relatable perspective on how these feelings can affect even accomplished professionals.
Drawing insights from Dr. Steve Peters' The Chimp Paradox and other tools, Alun explains how our "inner chimp" drives insecurities and outlines actionable steps to regain control. -
What makes a great leader?
How do you build trust, influence others, and create real value in your organization?
In this episode of The Effective Statistician, I show you how to grow as a leader by following a powerful cycle: learn, do, reflect, and start again.
Leadership goes beyond authority—it’s about taking action, communicating effectively, and driving meaningful change. I share practical steps you can apply right away to strengthen your skills and make an impact.
If you’re ready to take charge and become a more effective leader, this episode will guide you every step of the way! -
Planning for 2025 doesn’t have to be overwhelming—it can be a powerful exercise in aligning your goals with your ideal lifestyle and long-term aspirations. In this episode, Alun Bedding provides actionable strategies and thoughtful insights to help you approach the year ahead with clarity and purpose. Whether you’re aiming to elevate your career, find balance, or simply refine your approach to goal-setting, this episode is packed with ideas you won’t want to miss. So, listen now and take the first step toward making 2025 your most impactful year yet. And if you found this episode valuable, don’t keep it to yourself—share it with friends and colleagues who could benefit from these transformative strategies!
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How do we find the right dose in immune-oncology trials?
Is the traditional “maximum tolerated dose” approach still enough, or should we also focus on efficacy?
In this episode of The Effective Statistician, I talk with Teppo Huttunen, a seasoned statistician and co-founder of the boutique CRO, Estimeds. We uncover the shortcomings of the conventional three-plus-three design and explain how the Bayesian Optimal Interval (BOIN) design gives us more flexibility and better insights. Teppo shares practical tips on dose optimization and highlights the critical role statisticians play in shaping smarter, evidence-based decisions for phase two trials.
If you want to learn how we can balance safety, efficacy, and practical challenges in oncology studies, this episode is for you! -
Are you feeling stuck or overwhelmed in your work as a statistician?
Do you wonder how to stay sharp and maintain balance while tackling complex challenges?
In this Friday episode of The Effective Statistician, my co-host for, Alun Bedding, takes the lead to unpack the concept of "sharpening the saw," inspired by Stephen Covey's Seven Habits of Highly Effective People. Alun dives into the art of continuous renewal—physical, mental, social, and spiritual—to help you stay proactive and effective. He shares practical tips, personal insights, and lessons from recent PSI webinars, offering actionable steps to improve focus and boost productivity.
Listen in and discover how small, intentional changes can sharpen your edge as a statistician! -
Welcome to this episode of The Effective Statistician! Today, I explore an exciting and rapidly growing field: digital health interventions.
Have you ever wondered how to define engagement with these tools?
Why does measuring engagement matter so much for their success?
And how can statisticians solve the unique challenges that come with this digital space?
I speak with Jack Elkes, a PhD researcher focused on digital health, to answer these questions. Together, we tackle the complexities of these interventions, their use in areas like mental health, and how tools like cluster analysis help make sense of multidimensional data. With over 10,000 mental health apps already on the App Store, this field expands rapidly, creating opportunities and challenges.
If you want to know how engagement in digital health connects to marketing strategies or how these tools reshape decentralized trials, you’ll find plenty of insights here. Let’s dive in! -
Have you ever thought about how clinical trials affect the environment?
I hadn’t, until I spoke with Annie Wright, a first-year PhD student at Imperial College who is passionate about greener research. In this episode, we uncover how clinical trials contribute to climate change, from travel emissions to operational inefficiencies. We dive into practical actions statisticians and researchers can take to reduce the carbon footprint of trials, like adopting decentralized approaches and streamlining study designs.
Join us as we explore how to transform clinical research into a more sustainable practice while still delivering valuable scientific outcomes. -
Have you faced the challenge of dealing with non-proportional hazards in survival analysis?
In this episode, I team up with Kaspar Rufibach, a statistical methodology expert, to break down what proportional hazards mean, why the assumption often fails, and how you can tackle these situations effectively.
We explain key concepts like hazard functions, discuss practical ways to analyze and visualize survival data, and share strategies for designing better clinical trials.
Whether you’re working on your first survival analysis or refining your approach, this episode will equip you with the tools to address non-proportional hazards confidently. -
Introduction to Episode: "How Real Leaders Help Their People Grow Professionally and Personally"
What does it take to be a great leader?
How do you build trust, inspire growth, and create real value for your team and organization?
In this episode of The Effective Statistician, I sit down with Aziza Yormirzaeva and Klaus Breuer to answer these questions. Aziza shares how Klaus, her former manager, guided her to discover her passion for statistics and grow both as a professional and as a person. Klaus explains how he empowers his team, fosters trust, and creates a workplace culture that prioritizes learning and collaboration.
Their story is filled with practical lessons, inspiring moments, and insights that will challenge how you think about leadership and personal growth.
Let’s jump right into this fascinating conversation! -
What makes gene therapy so different from traditional drug development?
How do we address safety when each patient only receives a single dose?
And why are statisticians so essential in this process?
In this episode of The Effective Statistician, I sit down with Oscar Segurado, an MD, PhD, an expert in gene and cell therapies, to answer these questions and more. Oscar draws on decades of experience in academia, med tech, and biopharma—including his work on the blockbuster drug Humira—to guide us through the complexities of clinical development in gene therapy. We discuss everything from early clinical trials to commercialization, uncovering the unique challenges of treating rare diseases like hemophilia A and spinal muscular atrophy.
Whether you’re a statistician, data scientist, or just curious about the future of medicine, this episode offers valuable insights into the clinical development of gene therapies and the vital role statisticians play in advancing these groundbreaking treatments. -
What if we could target genetic diseases at their root, offering lifelong cures instead of temporary solutions?
And what role do statisticians play in making this breakthrough possible?
In this episode of The Effective Statistician, I dive into the fascinating world of gene therapy—an area packed with both promise and complexity.
I'm thrilled to finally cover this revolutionary field with two expert guests, Avery McIntosh from Pfizer and Alex Sverdlov from Novartis. Together, we break down the science behind gene therapies, explore the ethical and logistical challenges, and reveal how statisticians drive these life-changing treatments forward.
So, how close are we to curing diseases through gene therapy? Let’s jump in and find out. -
What does it take to create an effective clinical development plan? How do our early decisions shape the path of a compound through clinical phases? And how can statisticians actively balance the demands of science, speed, and cost in drug development?
In this special 400th episode of The Effective Statistician, I dive into these questions with Carrie Li, a biostatistics expert whose career spans both big pharma and startups. Carrie shares how she builds clinical development plans from scratch, collaborates with cross-functional teams, and uses statistical expertise to create strategies that drive both scientific and commercial success.
Join us as we explore the impact statisticians have on the clinical development journey. -
Have you wondered how large language models (LLMs) like ChatGPT are transforming the way we work?
How can AI tools boost efficiency in statistics and pharmaceutical research?
In this episode of The Effective Statistician, I talk with Pietro Mascheroni from Boehringer Ingelheim to answer these questions. Pietro, a physicist, shares how LLMs are being used in real-world applications, from simplifying document retrieval to enhancing data exploration and refining code.
We dive into why it’s crucial to maintain human oversight, how AI can improve team communication, and the challenges in validating these models.
If you're eager to learn how AI can revolutionize your work or help you stay ahead in this fast-paced field, tune in to this insightful episode! -
Are you a statistician looking to expand your career beyond the statistics department?
Do you want to know how your data expertise and strategic thinking can open new doors?
In this episode of The Effective Statistician podcast, I sit down with Swarna Khare, who made that leap and found success in strategic roles across the industry. We explore her journey, discussing how statisticians can leverage their skills to create a bigger impact outside of technical roles.
If you're ready to take your career to the next level, this episode is packed with actionable insights to help you step beyond the statistics function and into new opportunities. - Se mer