Spilt
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Some huge data coming out of #ESMO21 this week! And as ever, the amazing STAMPEDE trial delivers another practice-changing headline grabber. This time it's a focus on so-called "M0 high-risk" patients in STAMPEDE, with clear data showing that the addition of two years of abiratrone acetate to standard of care provides a massive benefit in metastasis-free survival and overall survival.
We are joined today by STAMPEDE co-PI Professor Noel Clarke, Urologist and Professor of Urological Oncology at the Christie NHS Foundation Trust, and Professor Silke Gillessen, Medical Oncologist at the Oncology Institute of Southern Switzerland, and also a STAMPEDE investigator. Silke is also the co-Chair of the fantastic Advanced Prostate Cancer Consensus Conference (APCCC) which we also discuss today (see link for upcoming virtual APCCC in October).
Regular hosts Professor Declan Murphy and Dr Renu Eapen are also joined in studio by Associate Professor Arun Azad, Medical Oncologist at Peter MacCallum Cancer Centre.
Once again, we are cross-posting to YouTube so you can watch the team enjoy a lively discussion!
Links
GU Cast on YouTube
APCCC upcoming meeting
Silke Gillessen Twitter
APCCC Twitter -
So said UCSF Oncologist and major league podcaster Dr Vinay Prasad in his recent Plenary Session podcast, reviewing the VISION trial in NEJM. We have already covered VISION here at GU Cast, but we decided to invite Vinay on the podcast to de-visit VISION and other aspects of trial design. Vinay is a Haematologist Oncologist at the University of California, San Francisco, and researcher interested in health policy. He is author of "Malignant", and has huge listenership to his Plenary Session Podcast and YouTube channel. He is certainly not afraid to call out issues with trial design and health policy! We have often used clips of his on GU Cast to illustrate issues with GU trials.
Plus we welcome back Professor Michael Hofman, Nuclear Medicine Physician who leads all things PSMA at Peter MacCallum Cancer Centre.
Regular hosts Dr Renu Eapen and Professor Declan Murphy at the helm.
Streaming also on Declan's YouTube channel
Links:
Dr Vinay Prasad Twitter
Plenary Session podcast on VISION
Plenary Session Patreon
Vinay YouTube
GU Cast/PCF webinar on VISION -
These two old mates join us for a "robust discussion" on the role of prostate MRI in the early detection of prostate cancer!
Dr Ben Davies, Professor of Urology, University of Pittsburgh, and Dr Matt Cooperberg, Urologic Oncologist at the University of California, San Francisco, certainly have differing views on the value of MRI in the early detection of prostate cancer. This was most evident on twitter after Matt et al (Andrew Vickers and Sigrid Carlsson), penned a piece in European Urology recently which was pretty negative about MRI.
No holds barred here as Ben has a crack at Matt's enthusiasm for genomic testing, and his scepticism about MRI. Plus some observations about disclosures.... got to tune in!!! A classic.
Plus we're now posting some GU Cast episodes on Youtube. See links below. This was a particularly good one to watch!!!
Links:
GU Cast on YouTube
Matt's Eur Urol paper (paywall sorry)
Ben Davies Twitter
Matt Cooperberg Twitter
