Episodes
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If you're struggling with back pain, neck pain or unexplained body aches, the answer might not be where it hurts. Learn how your brain, stress, sleep and movement all shape pain.
Dr Anisha Joshi is an osteopath and author of Heal Your Back. She joins Dr Karan to debunk the biggest myths about body pain.
Timestamps
(0:00) Intro - What you don’t realise about the pain in your body
(1:57) What is an osteopath?
(3:42) The daily mistakes making your pain worse
(5:25) Does pain equal damage?
(8:58) What causes back pain?
(13:17) The link between poor sleep and back pain
(14:38) What is sciatica?
(17:15) How breathing can reduce pain
(20:26) Is running bad for your knees and joints?
(23:05) What causes neck pains?
(24:35) Can you “fix” a neck hump?
(27:39) Are you hurting yourself when cracking your neck or back?
(31:27) Do massage guns and foam rollers work?
(33:40) Can ancestral movements help?
(35:28) Daily exercises to improve mobility and reduce pain
(37:54) A bedtime routine for a healthier back
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🚽 Throne Science
Discover the world’s first continuous tracker for getting personalized insight about gut health, hydration, and prostate health with every flush.
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📧Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity:
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📕 This Book May Save Your Life
The No.1 Sunday Times bestseller packed with evidence-based advice to improve your health.
https://geni.us/DrKaranBook
📕 This Is Vital Information
Order my new book covering everything you're too embarrassed to ask your doctor but really should.
https://linktr.ee/ThisisVitalInformation
🤖 Dr Karan's Digital Twin
Ask my AI twin your health questions anytime.
http://DrKaran.ai
About Dr Karan:
Dr. Karan Rajan is a doctor, author, Founder of LOAM Science and Chief of Science at Throne Science, dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor.
📱Connect with me:
Instagram: https://www.instagram.com/drkaranrajan/
TikTok: https://www.tiktok.com/@dr.karanr
Facebook: https://www.facebook.com/DrKaranR/
Website: www.drkaranrajan.com
X: https://twitter.com/drkaranrajan
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💬 If you want to live longer, stay independent and have more energy, you don't need another fitness hack - you need to move more.
⚡️ Walking, building strong legs, improving grip strength and simply moving more every day could have a bigger impact on your health than the perfect workout routine.
In this episode Dr Karan is joined by Dan Go, a high-performance health coach who helps busy people get fit, build sustainable habits, and stay healthy for the long run.
🎧 Stay tuned to find out:
➡︎ Why daily movement matters more than a perfect gym routine
➡ Why you need to try The Japanese Method of interval walking training
➡︎ Why strong legs are one of the biggest predictors of healthy ageing
➡︎ How farmer’s carries can reshape your body and extend your lifespan
➡︎ Why showing up is the only habit you need to learn
#DrKaran, #Walking, #Longevity, #HealthyAging, #StrengthTraining, #ExerciseScience, #FitnessTips, #HealthPodcast
Don't miss an episode! Subscribe NOW: https://www.youtube.com/@DrKaran?sub_confirmation=1
📕 Chapters
(0:00) Intro - How to work out sustainably
(3:45) Why walking beats running for most people
(8:58) Are desk treadmills actually worth it?
(12:28) Why daily movement matters more than the gym
(19:46) The farmer's carry: one of the best functional exercises
(22:30) Why strength becomes even more important as you age
(27:46) How to start exercising consistently
(33:48) Resting heart rate: what yours says about your health
(36:10) Should you track calories?
(42:57) How your breakfast sets the tone
(47:00) Dan's dream supplement stack
🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com
🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe
🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook
📕 Pre-order my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation?utm_source=linktree_profile_share<sid=472cbbde-00e2-42ab-8a3f-725656fab3a5
🔥 Head to https://loamscience.com/ try LOAM - and get an additional 10% with code POD10.
🎙️ An OG Podcasts production.
About Dr Karan:
Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.
📱Connect with me:
Instagram: https://www.instagram.com/drkaranrajan/
Facebook: https://www.facebook.com/DrKaranR/
TikTok: https://www.tiktok.com/@dr.karanr
X: https://twitter.com/drkaranrajan
Website: https://linktr.ee/ThisisVitalInformation
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Missing episodes?
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💬 Skin conditions affect a massive proportion of the population. Most people reach for creams and retinoids first - but the solution is often much simpler. So what should you do to protect your skin microbiome and reduce signs of aging?
⚡️ Dr Thivi Maruthappu is a consultant dermatologist, nutrition researcher, and author of Skin Food: Your 4-Step Solution to Healthy, Happy Skin.
⚡️ In this episode, Thivi and I discuss what your skin can reveal about your overall health, the science behind specific skin conditions, why a good skincare routine isn't always enough, and the growing evidence linking skin conditions to your gut microbiome.
🎧 Stay tuned to find out:
➡︎ Whether skin issues are a sign of a deeper health issue
➡ If supplements like collagen are actually effective
➡︎ What might be causing your rosacea or eczema
➡︎ Whether putting food on your face actually works
➡︎ Why your nails may reveal more about your health than you realise
#DrKaran, #MedicalScience, #HealthEducation, #HealthTips, #SkinCareRoutine, #SkinHealth, #DietAdvice, #NutritionScience
Don't miss an episode! Subscribe NOW: https://www.youtube.com/@DrKaran?sub_confirmation=1
📕 Chapters
(0:00) Intro
(04:18) Your skin is a microbiome
(04:11) How your diet impacts your skin
(07:21) Ozempic face
(09:13) Gut/skin connection
(21:01) Strict diets
(24:57) Collagen
(27:40) Nutrient and vitamin deficiency
(30:39) Hormones and skin health
(32:53) Tips to maintain skin health
(37:50) Perfect skin diet
🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com
🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe
🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook
📕 Pre-order my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation?utm_source=linktree_profile_share<sid=472cbbde-00e2-42ab-8a3f-725656fab3a5
🔥 Head to https://loamscience.com/ try LOAM - and get an additional 10% with code POD10.
🎙️ An OG Podcasts production.
About Dr Karan:
Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.
📱Connect with me:
Instagram: https://www.instagram.com/drkaranrajan/
Facebook: https://www.facebook.com/DrKaranR/
TikTok: https://www.tiktok.com/@dr.karanr
X: https://twitter.com/drkaranrajan
Website: https://linktr.ee/ThisisVitalInformation
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💬 If you improve your foot health and strength, you’ll not only fix back pain and bunions - you’ll increase your lifespan and improve your brain health!
⚡Most of us ignore our feet, squishing them into tight, cushioned shoes. But weak feet can cause problems throughout the body - and fixing them is easier than you think.
Dr Courtney Conley and Dr Jenifer Perez are the founders of Gait Happens - and experts in foot health. They join Dr Karan to share the top things you should start doing now.
🎧 Stay tuned to find out:
➡ Why back, hip and knee pain so often starts at the feet
➡︎ How to undo the damage of bunions and plantar fasciitis
➡︎ Why flat feet aren’t a death sentence
➡︎ Whether barefoot shoes are really worth your money
➡︎ Simple things parents can do to protect their kid’s feet
➡︎ Training and gadgets you can use for strong feet
#DrKaran, #MedicalScience, #HealthEducation, #HealthTips, #FootHealth, #BarefootShoes, #ToeStrength, #PlantarFasciitis
Don't miss an episode! Subscribe NOW: https://www.youtube.com/@DrKaran?sub_confirmation=1
📕 Chapters
(0:00) Introduction - How foot strength affects your brain, lifespan and entire body
(2:13) What you’re doing to weaken your feet
(3:09) Why foot strength becomes increasingly important beyond 50
(5:54) How to fix bunions
(7:33) Why plantar fasciitis is so hard to get rid of
(10:38) What are the signs of a weak foot?
(14:00) How far up the chain do feet problems impact?
(16:36) Biggest mistakes people make when buying shoes
(21:50) Are barefoot/minimalist shoes worth it?
(26:36) Should you spend more time barefoot?
(28:10) Best ways to protect our children's feet
(32:32) Favourite daily foot strengthening exercises
(38:33) One thing anyone can start doing today
🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com
🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe
🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook
📕 Pre-order my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation?utm_source=linktree_profile_share<sid=472cbbde-00e2-42ab-8a3f-725656fab3a5
🔥 Head to https://loamscience.com/ try LOAM - and get an additional 10% with code POD10.
🎙️ An OG Podcasts production.
About Dr Karan:
Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.
📱Connect with me:
Instagram: https://www.instagram.com/drkaranrajan/
Facebook: https://www.facebook.com/DrKaranR/
TikTok: https://www.tiktok.com/@dr.karanr
X: https://twitter.com/drkaranrajan
Website: https://linktr.ee/ThisisVitalInformation
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💬 Should you be taking peptides? From anti-aging promises to superhuman healing - peptides are massively hyped right now, and are being aggressively marketed online. But here’s why you should think twice before giving in to the marketing.
⚡While there are many FDA-approved peptides that you can get your hands on, most of the hype right now is focussed on grey-market, unregulated drugs. Things like BPC-157, TB-500 and the “Wolverine stack”.
In this AMA, Dr Karan answers your top questions about peptides and breaks down the real science behind the online claims.
🎧 Stay tuned to find out:
➡ What a peptide actually is - explained as simply as possible
➡︎ Whether peptides in skincare actually work - and how they differ from injectables
➡︎ If peptides can slow down aging - or help with autoimmune diseases
➡︎ Why marketing is drawing comparisons between peptides and GLP-1s
➡︎ If BPC-157 actually helps with healing and recovery - and the possible dangers
➡︎ The side effects of injecting peptides your body doesn't actually need
#PeptideTherapy, #LongevityScience, #EvidenceBasedHealth, #Biohacking, #HealthPodcast, #DrKaran, #MedicalMythsDebunked
Don't miss an episode! Subscribe NOW: https://www.youtube.com/@DrKaran?sub_confirmation=1
📕 Chapters
(0:00) Introduction
(1:18) What is a peptide?
(4:11) Difference between skincare peptides and injectables
(6:03) Which peptides are FDA-approved?
(7:58) Why people compare GLP-1s with peptides
(9:22) Why isn’t the FDA cracking down on illegal sales?
(11:05) The real science of BPC-157
(12:58) Have these peptides been studied for cancer causing effects?
(15:16) Side effects of injecting peptides you don’t need
(17:04) Are the anti-aging claims really true?
(18:53) Do peptides help with autoimmune diseases?
(20:14) What is the “Wolverine stack”?
(22:03) Is there a best way to take peptides?
(23:12) Overview and summary
🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com
🤖 Discover my digital twin here: http://DrKaran.ai
🔥 Head to https://loamscience.com/ try LOAM - and get an additional 10% with code POD10.
🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe
🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook
📕 Order my new book, This Is Vital Information, here: https://amzn.eu/d/0gfgOXFo
🎙️ An OG Podcasts production.
About Dr Karan:
Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.
📱Connect with me:
Instagram: https://www.instagram.com/drkaranrajan/
Facebook: https://www.facebook.com/DrKaranR/
TikTok: https://www.tiktok.com/@dr.karanr
X: https://twitter.com/drkaranrajan
Website: https://linktr.ee/ThisisVitalInformation
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Prostate cancer is the most common cancer in men, but it often has no obvious symptoms.
In this episode, Dr Karan Rajan speaks with Professor Prabhakar Rajan, a urologist and prostate cancer specialist, about prostate cancer risk, PSA testing, MRI scans, treatment choices, testicular cancer, and why men often delay asking for help.
They discuss when urinary symptoms, blood in urine, persistent back pain, testicular lumps, and changes in sexual or urinary function should be checked. While also unpacking the controversy around PSA screening, overdiagnosis, active surveillance, robotic prostatectomy, focal therapy, radiotherapy, and the future of AI in prostate cancer diagnosis.
This is a practical, evidence-led conversation about men’s health, prostate cancer, testicular cancer, screening, stigma, and the questions men should feel able to ask their doctor.
💩 Head to https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaranexplores to try LOAM - and get an additional 10% with code POD10.
💊 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe
🚽 Discover Throne's incredible new smart toilet device at http://thronescience.com
📘 For more useful science for your everyday life, grab my best selling book "This Book May Save Your Life": https://geni.us/DrKaranBook
📕 Get my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation
🤖 Discover my digital twin here: http://DrKaran.ai
🧬 Sign up for my Microbiome Course waitlist: https://drkaran.kit.com/microbiome-course-waitlist
About Dr Karan:
Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.
📱Connect with me:
Instagram: / drkaranrajan
Facebook: / drkaranr
TikTok: / dr.karanr
X: / drkaranrajan
Website: www.drkaranrajan.com
00:00 Prostate cancer symptoms men should know
01:02 Meet Professor Prabhakar Rajan
02:00 Why prostate cancer can have no symptoms
05:28 Are we overtreating early prostate cancer?
06:31 Surgery, radiotherapy and active surveillance
07:51 How MRI changed prostate cancer diagnosis
08:30 Why men avoid prostate health conversations
10:24 Prostate cancer risk in Black men
13:00 PSA tests: useful, imperfect and controversial
21:56 Why treatment decisions must be personal
24:39 Questions to ask before prostate surgery
25:10 Active surveillance and focal therapy
26:20 Nerve-sparing prostatectomy explained
28:22 Sexual function after prostate surgery
30:06 Testicular cancer symptoms in young men
31:18 What to do if you find a testicular lump
34:17 How to check your testicles properly
38:05 Could AI help diagnose prostate cancer?
40:25 The one thing men should do for their health
41:02 Why men’s health needs better conversations
#MensHealth #DrKaranRajan #MensHealthPodcast #Podcast
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Gut health is about much more than what you eat. In this episode, Dr Karan Rajan speaks with Kaitlin Colucci about the gut-brain connection, IBS, bloating, stress, sleep, meal timing, yoga, and the nervous system.
They discuss why diet may only be one part of the gut health puzzle, how stress can affect digestion, why eating on the go may worsen symptoms, and how simple habits like breathwork, better sleep, mindful eating, fibre, and movement can support a healthier gut.
Kaitlin explains how the gut and brain communicate through the nervous system, why IBS is often misunderstood, and why gut symptoms are not always “just a food problem”.
This conversation also explores ultra-processed foods, caffeine, alcohol, artificial sweeteners, protein bars, fizzy drinks, meal timing, the migrating motor complex, yoga for IBS, and the role of social connection in digestion.
In this episode:
-Why gut health is not just about diet- How stress affects digestion and gut motility
- What the gut-brain axis actually means
- Why IBS can involve nervous system sensitivity
- How sleep and circadian rhythm affect the gut
- Why grazing all day may worsen bloating
- How yoga, meditation, and breathwork may support IBS symptoms
- Practical ways to eat more mindfully
- The role of fibre, meal timing, and food diversity
💩 Head to https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaranexplores to try LOAM - and get an additional 10% with code POD10.💊 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe
🚽 Discover Throne's incredible new smart toilet device at http://thronescience.com
📘 For more useful science for your everyday life, grab my best selling book "This Book May Save Your Life": https://geni.us/DrKaranBook
📕 Get my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation
🤖 Discover my digital twin here: http://DrKaran.ai
🧬 Sign up for my Microbiome Course waitlist: https://drkaran.kit.com/microbiome-course-waitlist
About Dr Karan:
Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.
Connect with me:
Instagram: / drkaranrajan
Facebook: / drkaranr
TikTok: / dr.karanr
X: / drkaranrajan
Website: www.drkaranrajan.com
00:00 Welcome Kaitlin Colucci
01:34 Gut Health Rapid-Fire
07:42 Why Eating on the Go Affects Digestion
08:23 What People Miss About Gut Health
09:04 The Gut-Brain Connection Explained
11:16 How Stress Impacts Digestion
12:21 IBS, Gut Sensitivity & Visceral Hypersensitivity
15:26 How to Regulate Your Nervous System
16:29 Mindful Eating, Food Diaries & Eating Without Distractions
19:04 Reconnecting With Food & Social Eating
22:13 Sleep, Circadian Rhythm & Gut Health
23:37 Meal Timing, Grazing & the Gut “Clean-Up Crew”
28:25 Yoga, IBS & Final Gut Health Advice
36:46 Modern Gut Health & Final Takeaways
#GutHealth #IBS #GutBrainAxis #DrKaranRajan #KaitlinColucci -
Male fertility is declining, but sperm count is only part of the story.
Dr Karan Rajan chats with Professor Sheryl Homa about male infertility, sperm DNA damage, lifestyle, heat exposure, environmental toxins, microbiome health, and why men’s fertility is often overlooked.
Professor Homa explains why infertility should be treated as a health issue for both partners, what semen analysis can and cannot tell you, and why sperm health may reflect wider problems such as diabetes, inflammation, kidney disease, hemochromatosis, stress and metabolic health.
In this conversation, we cover:
• Why global sperm counts appear to be falling
00:00 Sperm Counts Are Falling Globally
Head to https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaranexplores to try LOAM - and get an additional 10% with code POD10.
Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe
Discover Throne's incredible new smart toilet device at http://thronescience.comFor more useful science for your everyday life, grab my best selling book "This Book May Save Your Life": https://geni.us/DrKaranBook
Get my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation
Discover my digital twin here: http://DrKaran.ai
Sign up for my Microbiome Course waitlist: https://drkaran.kit.com/microbiome-course-waitlist
About Dr Karan:
Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.
Connect with me:
Instagram: / drkaranrajan
Facebook: / drkaranr
TikTok: / dr.karanr
X: / drkaranrajan
Website: www.drkaranrajan.com
#MaleFertility #SpermHealth #MensHealth #DrKaran #podcast -
Your gut microbiome affects far more than digestion. In this episode, Dr Karan Rajan sits down with gut health expert Jordan Haworth to break down the science of gut health, probiotics, fibre, acid reflux, oral microbiome health, fermented foods, GLP-1, bloating, sleep, fasting, and the everyday habits that actually improve your microbiome.
Here is a link to preorder Jordan's new book out June 18th: How to Gut Health: Science-backed hacks for immunity, metabolism and better sleep
https://lnk.to/howtoguthealth
The connection between oral health and gut healthWhy chewing food properly changes digestionThe truth about probiotics and fermented foodsBest foods for beneficial gut bacteriaGut-friendly habits that improve digestion naturallyAcid reflux hacks backed by scienceWhether greens powders and fibre gummies are worth itThe role of fasting, sleep, exercise and stress on the microbiomeWhy gut health affects metabolism, immunity, mood and more
We speak about:
00:00 Gut Health Starts In The Mouth
01:15 Why Chewing Improves Digestion
04:10 Eating Slowly, GLP-1 & Feeling Full
06:55 Oral Microbiome, Mouthwash & Gum Disease
11:25 Acid Reflux & The Lower Oesophageal Sphincter
19:40 Bitter Foods, Coffee & Digestion
22:05 Nausea, Ginger & Fart Walking
31:00 Foods That Feed Bifidobacteria
34:00 Fermented Foods & Lactic Acid Bacteria
37:50 Slow-Fermenting Fibres For The Colon
40:35 Prebiotics, Probiotics & Postbiotics Explained
50:40 Nature, Sleep, Exercise & The Microbiome
53:10 Fasting, Akkermansia & Gut Rest
54:45 Sweeteners, Vinegar, Greens Powders & Fibre Gummies
Head to https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaranexplores to try LOAM - and get an additional 10% with code POD10.
Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe
Discover Throne's incredible new smart toilet device at http://thronescience.com
For more useful science for your everyday life, grab my best selling book "This Book May Save Your Life": https://geni.us/DrKaranBook
Get my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation
Discover my digital twin here: http://DrKaran.ai
Sign up for my Microbiome Course waitlist: https://drkaran.kit.com/microbiome-course-waitlist
About Dr Karan:
Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor.
Connect with me:
Instagram: / drkaranrajan
Facebook: / drkaran
TikTok: / dr.karanr
X: / drkaranrajan
Website: www.drkaranrajan.com
#GutHealth #Microbiome #DigestiveHealth #Probiotics #DrKaran -
Your phone is not just distracting you, it may be changing what your brain finds rewarding.
In this episode of Dr Karan Explores, Dr Karan Rajan speaks with neuroscientist TJ Power, founder of DOSE Lab, about dopamine, phone addiction, AI, “brain rot,” digital anhedonia, and why modern technology can make ordinary life feel less pleasurable. TJ’s DOSE framework focuses on dopamine, oxytocin, serotonin, and endorphins, the four brain chemicals he says are being disrupted by the way modern humans live.
This conversation explores why so many of us feel stuck in loops of scrolling, distraction, apathy, and low motivation, and what it takes to reset our relationship with stimulation without pretending technology is “bad.” TJ shares why he believes 72 hours without screens can feel transformative, why boredom is harder than it sounds, and why becoming a “professional unplugger” may be one of the most important skills for the next generation.
In this episode, we cover:
What dopamine actually does beyond the online “dopamine detox” clichésWhy phones, short-form content, sugar, alcohol, and AI can hijack reward pathways“Digital anhedonia”: Why normal life can start to feel dull or boringThe 72-hour unplugged experiment and what happens by day two and day threeWhy boredom, stillness, walking, and doing nothing can restore creativityThe default mode network and why your best ideas may need silenceAI, “brain rot,” passive screen time, and outsourcing your thinkingHow to become a “professional unplugger” without quitting modern life🎬 Chapters
01:13 – Why Modern Life Is Rewiring Our Brains
03:18 – What Dopamine Actually Does
06:06 – Phones, Short-Form Content & Dopamine Overload
09:28 – Why Nothing Feels Fun Anymore
12:27 – How to Break the Stimulation Loop
14:01 – 72 Hours Without Screens: What Happens to Your Brain
17:49 – Boredom, Creativity & the Default Mode Network
21:41 – Instant Gratification and the Collapse of Waiting
22:47 – AI, Brain Rot & Outsourcing Your Thinking
29:34 – Passive Screen Time vs Active Technology Use
32:37 – Are Some Brains More Dopamine-Hungry?
39:04 – Stillness, Silence & Rebuilding Attention
42:35 – AI Relationships, Oxytocin & Artificial Connection
46:10 – Why Technology Evolves Faster Than the Human Brain
48:27 – Dopamine and Why Time Feels Faster
52:03 – Becoming a Professional Unplugger
53:31 – Final Takeaway: Quiet Mornings, Coffee & No Phone💩 Head to https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaranexplores to try LOAM - and get an additional 10% with code POD10.💊 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe🚽 Discover Throne's incredible new smart toilet device at http://thronescience.com📘 For more useful science for your everyday life, grab my best selling book "This Book May Save Your Life": https://geni.us/DrKaranBook📕 Get my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation🤖 Discover my digital twin here: http://DrKaran.ai🧬 Sign up for my Microbiome Course waitlist: https://drkaran.kit.com/microbiome-course-waitlistAbout Dr Karan:Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.📱Connect with me:Instagram: / drkaranrajanFacebook: / drkaranrTikTok: / dr.karanrX: / drkaranrajanWebsite: www.drkaranrajan.com
#Dopamine #BrainRot #PhoneAddiction #Neuroscience #DigitalDetox
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💬 Protecting first time parents from the realities of childbirth comes at a price. Not knowing how difficult it can be often leaves them unprepared - feeling guilty if it doesn’t go “perfectly”.
⚡With all the misinformation around - and shockingly high maternal mortality rates in the US - Dr Jennifer Lincoln has decided to take childbirth into her own hands. The social media educator has just released The Birth Book: An OB-GYN’s Guide to Demystifying Labor and Delivery.
🎧 Stay tuned to find out:
➡ What a “normal” labour really looks like
➡︎ What you can say “no” to during labour (Hint: anything)
➡︎ The truth about epidurals, C-sections and natural birth
➡︎ That children can be healthy no matter how childbirth goes
➡︎ Why the US is the highest rich nation for maternal mortality
➡︎ How 1 in 3 births cause psychological trauma for the mum
#DrKaran, #Pregnancy, #BirthScience, #Labour, #BirthTrauma, #ChildbirthMyths #WomensHealth, #MedicalScience, #HealthEducation, #MythBusting
Don't miss an episode! Subscribe NOW: https://www.youtube.com/@DrKaran?sub_confirmation=1
📕 Chapters
(0:00) Introduction - We need to be realistic about childbirth
(2:10) How should women really prepare for birth?
(3:27) Are doctors good patients when it comes to childbirth?
(5:16) What does a normal first time labour really look like?
(7:11) How to know when it’s time to go to the hospital
(8:28) Should you pack a hospital bag?
(10:07) What it really means to induce labour
(14:09) Is there a best birthing position?
(16:37) What can you say “no” to?
(18:54) How to tell the difference between optional and necessary interventions
(20:23) How different is second time labour?
(22:38) What to do when a baby’s breach
(24:22) Why you shouldn’t feel guilty about an epidural
(28:51) Does vaginal seeding help?
(29:25) Conversations to have before labour starts
(31:56) The problem of “maternity deserts” in the US
(34:52) Why maternal mortality is so high in the US
(35:57) Why do black women have the worst childbirth outcomes?
(39:16) What to consider if you’re having a homebirth
(40:09) Why traumatic births are much more common than we realise
🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com
🤖 Discover my digital twin here: http://DrKaran.ai
🔥 Head to https://loamscience.com/ try LOAM - and get an additional 10% with code POD10.
🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe
🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook
📕 Pre-order my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation?utm_source=linktree_profile_share<sid=472cbbde-00e2-42ab-8a3f-725656fab3a5
🎙️ An OG Podcasts production.
About Dr Karan:
Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.
📱Connect with me:
Instagram: https://www.instagram.com/drkaranrajan/
Facebook: https://www.facebook.com/DrKaranR/
TikTok: https://www.tiktok.com/@dr.karanr
X: https://twitter.com/drkaranrajan
Website: https://linktr.ee/ThisisVitalInformation
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GLP-1 weight loss drugs are changing medicine, but are we talking about them in the right way? In this episode, Dr Karan Rajan speaks with Dr Federica Amati about GLP-1s, food noise, metabolic health, appetite, gut health, muscle loss, side effects and why nutrition support matters.
Dr Federica Amati explains why these medications should not be seen as simple “weight loss drugs”, how food noise differs from real hunger, and what people should know before, during and after GLP-1 treatment.
📗 Pre-order Dr Federica's book 'The Appetite Reset' here: https://shor.by/fP5H
In this conversation, we cover:
* Why diet remains one of the biggest drivers of chronic disease
* What GLP-1s actually do beyond weight loss
* The difference between homeostatic hunger, hedonic hunger and microbiome-driven hunger
* Why food noise can dominate appetite and eating behaviour
* How protein and resistance training can help protect muscle
* Why micronutrients, fibre and hydration matter on GLP-1s
* The risks of black market or poorly regulated weight loss injections
* How gut health may influence appetite, side effects and long-term success
* Why whole foods and nutrient density still matter most
Chapters
00:00 Preview: GLP-1s, food noise and diet
01:18 Welcome and Dr Federica Amati introduction
02:18 Why GLP-1s need lifestyle and nutrition support
03:21 Diet, chronic disease and preventable deaths
05:08 Who should be using GLP-1 medications?
07:18 Why GLP-1s are metabolic health medications
08:13 GLP-1s, the brain and food noise
08:51 Homeostatic, hedonic and microbiome-driven hunger
09:22 Internal vs external food noise
11:37 Practical ways to reduce food noise
13:40 Loam sponsor read
14:39 Why digestion starts in the brain
17:29 Fullness, stomach stretch and meal replacements
19:47 GLP-1s, muscle loss, protein and resistance training
21:02 Micronutrients, hydration and nutrient density
24:06 Supplements and Mediterranean dietary patterns
26:10 Body image, identity and emotional changes on GLP-1s
28:34 Regulation, TikTok access and black market risks
30:47 Gut microbiome, appetite and natural GLP-1 signalling
42:31 Preparing your gut, managing side effects and final advice
💩 Head to https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaranexplores to try LOAM - and get an additional 10% with code POD10.
💊 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe
🚽 Discover Throne's incredible new smart toilet device at http://thronescience.com
📘 For more useful science for your everyday life, grab my best selling book "This Book May Save Your Life": https://geni.us/DrKaranBook
📕 Get my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation
🤖 Discover my digital twin here: http://DrKaran.ai
🧬 Sign up for my Microbiome Course waitlist: https://drkaran.kit.com/microbiome-course-waitlist
About Dr Karan:
Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.
📱Connect with me:
Instagram: / drkaranrajan
Facebook: / drkaranr
TikTok: / dr.karanr
X: / drkaranrajan
Website: www.drkaranrajan.com
#GLP1 #WeightLossDrugs #FoodNoise #GutHealth #MetabolicHealth
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💬 How can you tell if a supplement actually does what it promises to do? There are so many on the market that are underdosed, understudied and not backed up by science. So before you choose your next supplement - this is the data that should inform your decision.
⚡When Dr Karan created LOAM, his aim was to create a fibre supplement backed up by clinically robust data. In this special episode, he outlines the lengthy process that went into making sure it actually delivers results.
🎧 Stay tuned to find out:
➡ What a preclinical study is - and why they are essential
➡︎ How a study can actually show you what’s going on inside someone’s gut
➡︎ Why propionate is so important for gut health - and how LOAM boosts it
➡︎ Why LOAM produces less gas and bloating than other fibre supplements
➡︎ What trials are coming in the future for LOAM
#DrKaran, #LOAM, #Supplements, #Microbiome, #Butyrate, #GutHealth, #MedicalScience, #HealthEducation, #MythBusting
Don't miss an episode! Subscribe NOW: https://www.youtube.com/@DrKaran?sub_confirmation=1
📕 Chapters
(0:00) Introduction - How to choose a supplement that works
(0:41) Why preclinical studies are so important
(4:27) The combination that creates gold standard results
(8:14) How the LOAM preclinical study actually worked
(11:44) Surprising results from the LOAM trials
(14:02) The importance of the short-chain fatty acid propionate
(17:43) Why LOAM produces results so quickly
(20:02) Why supplements don’t impact all people the same
(22:18) How LOAM produces less gas than other fibre supplements
(25:36) Fibre fermentation💩 Head to https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=spotify&utm_medium=podcast&utm_campaign=podcast_loam_clinical_trials
🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com
🤖 Discover my digital twin here: http://DrKaran.ai
🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe
🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook
📕 Pre-order my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation?utm_source=linktree_profile_share<sid=472cbbde-00e2-42ab-8a3f-725656fab3a5
🎙️ An OG Podcasts production.
About Dr Karan:
Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.
📱Connect with me:
Instagram: https://www.instagram.com/drkaranrajan/
Facebook: https://www.facebook.com/DrKaranR/
TikTok: https://www.tiktok.com/@dr.karanr
X: https://twitter.com/drkaranrajan
Website: https://linktr.ee/ThisisVitalInformation
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Sleepwalking into arthritis isn’t inevitable. And some changes can show up faster than most people expect.
In this episode, Dr Karan Rajan speaks with Professor Tamiko Katsumoto about why arthritis rates are rising, the differences between rheumatoid arthritis and osteoarthritis, and what the best evidence says about reducing joint inflammation, including a lifestyle medicine intervention where benefits were seen as early as 8 weeks (with the primary endpoint at 16 weeks).
This isn’t about “miracle cures.” It’s about stacking the odds in your favour: Diet quality, fibre, fermented foods, weight and metabolic health, sleep, stress, movement. And how these interact with inflammation, the gut, and joint symptoms.
In this episode, we cover:
∙ RA vs OA: Classic symptom patterns and why they’re treated differently
∙ Why treatments for osteoarthritis can feel limited (and why lifestyle is still worth discussing)
∙ “Food as medicine” and why joints are a symptom you can actually feel change
∙ The “Plants for Joints” study: What changed at 8 weeks and what the 16-week endpoint showed
∙ The gut-joint axis: Gut barrier, microbial diversity, and immune regulation
∙ Why some patients flare on ultra high meat / fibre-free approaches (and what to do instead)
∙ Practical “build my plate” guidance for joint and inflammation support
#Arthritis #JointPain #RheumatoidArthritis #Osteoarthritis #Inflammation
💩 Head to https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaranexplores to try LOAM - and get an additional 10% with code POD10.
💊 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe
🚽 Discover Throne's incredible new smart toilet device at http://thronescience.com
📘 For more useful science for your everyday life, grab my best selling book "This Book May Save Your Life": https://geni.us/DrKaranBook
📕 Get my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation
🤖 Discover my digital twin here: http://DrKaran.ai
🧬 Sign up for my Microbiome Course waitlist: https://drkaran.kit.com/microbiome-course-waitlist
About Dr Karan:
Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.
📱Connect with me:
Instagram: / drkaranrajan
Facebook: / drkaranr
TikTok: / dr.karanr
X: / drkaranrajan
Website: www.drkaranrajan.com
-
💬 One majorly overlooked part of health is your pelvic floor. You may think it’s just a worry for women - but men need to train their pelvic muscles too. The question is, how?
If you’re the type of person who spends a lot of time sitting all day, have ever experienced gut problems or back pain - or you just want to improve your physique - this one’s for you.
⚡Dr Kelly Peterson is the master of pelvic floor exercises - and shares all her best techniques in this episode.
🎧 Stay tuned to find out:
➡ The 3 types of people who need to work on their pelvic floor
➡︎ What the pelvic floor is actually doing day-to-day
➡︎ The difference between a weak and an overactive pelvic floor
➡︎ Why holding in your pee - and forcing out your poop - are big no-nos
➡︎ The exercises you can do - anywhere! - to strengthen your pelvic floor daily
#DrKaran, #PelvicFloor, #PoopHealth, #GutHealth, #BackPain, #BreathingTechniques, #WomensHealth, #MensHealth, #MedicalScience, #HealthEducation, #MythBusting
Don't miss an episode! Subscribe NOW: https://www.youtube.com/@DrKaran?sub_confirmation=1
📕 Chapters
(0:00) Introduction
(0:31) How do you train your pelvic floor?
(2:47) What does the pelvic floor actually do day-to-day?
(4:56) Difference between weak and overactive pelvic floor
(9:03) Common pelvic floor problems in men
(12:30) Big no-nos when you go for a poop
(16:14) Breathing techniques to use on the loo
(20:59) Should you worry about making sounds while on the toilet?
(23:02) How to potty train kids and turn them into super poopers
(28:34) Why you shouldn't pee ‘just in case’
(31:05) Tips to improve your pelvic floor - wherever you are
(33:29) How often should we do pelvic floor exercises?
🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com
🤖 Discover my digital twin here: http://DrKaran.ai
🔥 Head to https://loamscience.com/ try LOAM - and get an additional 10% with code POD10.
🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe
🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook
📕 Pre-order my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation?utm_source=linktree_profile_share<sid=472cbbde-00e2-42ab-8a3f-725656fab3a5
🎙️ An OG Podcasts production.
About Dr Karan:
Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.
📱Connect with me:
Instagram: https://www.instagram.com/drkaranrajan/
Facebook: https://www.facebook.com/DrKaranR/
TikTok: https://www.tiktok.com/@dr.karanr
X: https://twitter.com/drkaranrajan
Website: https://linktr.ee/ThisisVitalInformation
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Most people can’t name five menopause symptoms beyond hot flushes and the biggest problem might start with the word itself. In this episode, Dr Karan Rajan speaks with Dr Louise Newson, a hormone and menopause specialist, about what’s actually happening biologically, why symptoms get missed or mislabelled, and how evidence, guidelines, and real-world prescribing shape care.
In this conversation, we cover:
Why “menopause” as a label can obscure the underlying hormone biology
The three-hormone framework: Oestrogen, progesterone, testosterone
Why symptoms like brain fog, mood changes, and gut symptoms can be misattributed
Bioidentical vs synthetic hormones (and why molecular structure matters)
Osteoporosis risk, prevention, and what “healthy ageing” should include
Dosing and absorption: Patches vs gels, and why some people need higher doses
Why “guidelines” are a guide and where personalisation matters most
🎬 Chapters
01:22 – Most people can’t name five symptoms beyond hot flushes
01:56 – The definition problem: “A year without a period” doesn’t explain biology
02:59 – Back to basics: oestrogen, progesterone, testosterone
04:24 – Is menopause “just ageing” or a treatable deficiency state?
06:21 – Misdiagnosis: IBS, brain fog, depression and missed hormone deficiency
08:40 – Why “hard to measure” symptoms got ignored in research and guidelines
09:04 – Hormones and inflammation: metabolic risk shifts in perimenopause
10:32 – Osteoporosis risk and prevention: Why this matters clinically
11:22 – Sponsor: Loam
12:14 – Bioidentical vs synthetic hormones: The “key and lock” explanation
14:59 – Contraindications and breast cancer conversations
17:12 – Guidelines vs optimisation: Why safe does not always mean best
18:31 – How to read guidelines: Who wrote them, conflicts, and cited studies
20:18 – Dosing: “lowest effective dose” and why needs vary
22:25 – Louise’s own dosing story: Symptom improvement within days
24:14 – Absorption science: Skin variation and patch placement differences
26:01 – When to consider hormones: Symptoms and quality-of-life impact
27:18 – PMS and PMDD: Severe pre-period symptoms and hormone strategies
28:58 – The timing hypothesis and what WHI got wrong
31:04 – The “stop at 60” myth, synthetic-hormone data, and fear headlines
32:26 – The risks of not taking hormones
34:07 – Sponsor: Throne
35:11 – Gut microbiome and hormones: Reflux, bloating, and symptom shifts
41:29 – Outcomes and personalisation: The metric is quality of life
42:15 – Mental health outcomes discussion and clinic data
💩 Head to https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaranexplores to try LOAM - and get an additional 10% with code POD10.
💊 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe
🚽 Discover Throne's incredible new smart toilet device at http://thronescience.com
📘 For more useful science for your everyday life, grab my best selling book "This Book May Save Your Life": https://geni.us/DrKaranBook
📕 Get my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation
🤖 Discover my digital twin here: http://DrKaran.ai
🧬 Sign up for my Microbiome Course waitlist: https://drkaran.kit.com/microbiome-course-waitlistAbout Dr Karan:Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humour. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.📱Connect with me:Instagram: / drkaranrajanFacebook: / drkaranrTikTok: / dr.karanrX: / drkaranrajanWebsite: www.drkaranrajan.com
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💬 All your GLP-1 weight loss questions answered in this AMA with Dr Karan. Should you take them if you’re not overweight? Can you stay on them forever? How can you eat better when your appetite is gone?
⚡ Answering the questions sent in by you, Dr Karan explains the science, benefits, risks and ethics of using drugs like Ozempic, Wegovy Mounjaro and Tirzepatide.
🎧 Stay tuned to find out:
➡ Whether BMI matters when you’re thinking about going on GLP-1s
➡︎ If it’s safe to stay on GLP-1s forever - and how to come off safely
➡︎ Are maintenance doses and microdosing effective?
➡︎ How weight loss drugs affect the gut microbiome
➡︎ What to eat to hit fibre, protein and calorie targets when you have no appetite
➡︎ How hormones and women’s health conditions are impacted
➡︎ Why GLP-1s benefits extend way beyond weight loss
#DrKaran, #WeightLoss, #Ozempic, #Tirzepatide, #GutHealth, #GLP1, #AMA, #MedicalScience, #HealthEducation, #MythBusting
Don't miss an episode! Subscribe NOW: https://www.youtube.com/@DrKaran?sub_confirmation=1
📕 Chapters
(0:00) Introduction
(1:10) What is a GLP-1 agonist?
(2:00) Can fit people use Tirzepatide during a fat loss period to target visceral fat?
(3:58) What BMI do you need to have?
(5:22) Is everyone secretly on GLP-1s?
(6:03) Using GLP-1s for food noise, even if not overweight?
(8:00) Will the NHS soften the criteria for GLP-1s?
(8:55) Can you stay on GLP-1s forever?
(10:37) How to safely come off weight loss drugs
(12:03) Can you stop food noise once you come off the drugs?
(13:53) Are maintenance doses effective?
(14:57) Is microdosing GLP-1s an option?
(16:42) Short term vs long term side effects
(19:10) Is nausea a permanent side effect of weight loss drugs?
(20:16) Should you force yourself to eat?
(22:51) How to deal with “Ozempic face”
(24:13) Effect of GLP-1s on the gut microbiome
(26:32) How to eat enough while working out when you have no appetite?
(27:52) Can you build muscle on GLP-1s?
(29:56) Are hormones affected by GLP-1s?
(31:16) Can it help with endometriosis?
(32:53) Why LOAM can help while using GLP-1s
(34:29) Tips on high fibre, low calorie foods for GLP-1 users
(35:30) Inflammation, heart health - and other benefits of GLP-1s
🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com
🤖 Discover my digital twin here: http://DrKaran.ai
🔥 Head to https://loamscience.com/ try LOAM - and get an additional 10% with code POD10.
🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe
🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook
📕 Pre-order my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation?utm_source=linktree_profile_share<sid=472cbbde-00e2-42ab-8a3f-725656fab3a5
🎙️ An OG Podcasts production.
About Dr Karan:
Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.
📱Connect with me:
Instagram: https://www.instagram.com/drkaranrajan/
Facebook: https://www.facebook.com/DrKaranR/
TikTok: https://www.tiktok.com/@dr.karanr
X: https://twitter.com/drkaranrajan
Website: https://linktr.ee/ThisisVitalInformation
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Most people are missing one of the most important nutrients for long-term health: fibre.In this solo episode, Dr Karan breaks down everything you need to know about fibre. From the cheapest ways to get more, to when you should eat it, and how it impacts your gut, cholesterol, metabolism, and long-term disease risk.What You’ll Learn:The cheapest high-fibre foods (and why beans dominate)When to eat fibre for maximum benefitHow fibre affects your gut microbiomeWhether fibre supplements are worth itHow much fibre you actually needWhy most people are under-consuming fibreThe science behind bloating and fibre adaptationHow fibre supports long-term health and disease preventionKey Insights from the Episode:“Your gut health and your microbiome health should not be compromised by your budget.”“If the goal is maximum fibre for the least amount of money, you're not going to find better than beans and legumes.”“The best time to take your fibre is basically whenever you remember to take your fibre.”“Only 5% of us are feeding our gut properly.”“I managed to reverse my high cholesterol… through increasing dietary fibre intake.”
About Dr Karan:Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor.
🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com 🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 📕 Pre-order my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation?utm_source=linktree_profile_share<sid=472cbbde-00e2-42ab-8a3f-725656fab3a5🔥 Head to https://loamscience.com/ try LOAM - and get an additional 10% with code POD10.🤖 Discover my digital twin here: http://DrKaran.ai
📱Connect with me:Instagram: / drkaranrajanFacebook: / drkaranTikTok: / dr.karanrX: / drkaranrajanWebsite: www.drkaranrajan.com#GutHealth #Fibre#Microbiome #HealthScience #Nutrition
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💬 Exercise during pregnancy is surrounded by myths, fear, and outdated advice. But the truth is staying active can be one of the most powerful things you can do for both you and your baby.
⚡To unpack what safe, effective exercise really looks like during pregnancy and why misinformation is still so widespread - Dr Karan is joined by Dr Margie Davenport, professor and leading researcher in exercise during pregnancy. Whether you’re expecting, planning a pregnancy, or supporting someone who is, this conversation is essential listening.
🎧 Stay tuned to find out:
➡ Why there’s so much confusion and misinformation around exercise in pregnancy
➡︎ The science behind common myths about exercising while pregnant
➡︎ What “safe” exercise really looks like at each stage of pregnancy
➡︎ How physical activity benefits your baby’s health and development
➡︎ The role exercise plays in reducing the risk of serious complications
➡︎ Why outdated advice still persists in medical and public spaces
➡︎ How to approach exercise with confidence during pregnancy
#DrKaran, #PregnancyHealth, #PrenatalFitness, #ExerciseDuringPregnancy, #WomensHealth, #MedicalScience, #HealthEducation, #MythBusting
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📕 Chapters
(0:00) Introduction - The biggest myth regarding exercise and pregnancy
(1:00) Why exercise in pregnancy is surrounded by misinformation
(2:05) What the evidence says
(4:02) Exercise at different stages of pregnancy
(6:00) The role of epigenetic factors
(7:55) How exercise during pregnancy impacts a child's long-term health
(11:00) Exercise and gestational diabetes and preeclampsia
(12:03) How exercise affects labor outcomes
(13:50) Walking or aerobic exercise versus strength training
(16:50) The fear of miscarriage
(18:57) Exercises pregnant women should definitely avoid
(22:10) Weightlifting during pregnancy
(24:03) Taking creatine and supplements during pregnancy
(27:49) Optimal heart rate during pregnancy
(30:03) Exercise and high risk pregnancies
(33:02) How to conduct safe and ethical research in this area
(36:00) How to exercise safely postpartum
(41:00) Exercise and the gut microbiome
(42:57) What Margie is researching next
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About Dr Karan:
Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.
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Cooking isn’t just about flavour, it directly impacts your brain, gut, and heart health.
How food impacts brain function and mental healthWhy fibre is critical for your gut and brainThe truth about tofu, coffee, and mushroomsWhy “anti-inflammatory diets” actually matterThe gut-brain connection explained simplyHow cooking methods affect nutritionAnti-inflammatory curry pasteTofu (high-protein, low saturated fat)Fibre-rich vegetablesGinger, garlic, turmeric & spicesCashew cream alternative to coconut milk
In this special episode, Dr Karan teams up with The Brain Docs, Drs. Ayesha & Dean Sherzai, to cook a nutrient-dense curry while breaking down the real science behind food and its impact on your body. From fibre and omega-3s to anti-inflammatory ingredients and the gut-brain connection.
Discussed in the episode:
“the basic everyday food you eat literally makes your brain.”
“what happens in your gut determines everything.”
This is not about “superfoods”, it’s about dietary patterns, real ingredients, and how what you eat daily shapes your long-term health.
What You’ll Learn:
Anti-inflammatory curry pasteTofu (high-protein, low saturated fat)Fibre-rich vegetablesGinger, garlic, turmeric & spicesCashew cream alternative to coconut milk
What We Cook:Chapters:
00:00:30 – Intro
00:03:29 – “What happens in the gut determines everything”
00:04:24 – Tofu as the protein + the soy myth
00:06:51 – Coffee & cognition: What the data suggests
00:11:20 – Ginger for nausea & gut motility
00:12:36 – Dietary patterns over single foods (Mediterranean-style pattern explained)
00:16:55 – “Eat the rainbow”: Polyphenols, fibre types, carotenoids
00:19:29 – Omega-3 index & omega-3s as brain building blocks
00:20:19 – Omega-3 supplements: When it’s reasonable
00:22:23 – Prevention & the “pillars” analogy for long-term brain health
00:35:42 – Mental health & the gut: It’s multi-layered
00:36:24 – IBS: treating gut symptoms and mental health burden
00:48:01 – Turmeric for brain health & research background
00:49:20 – Turmeric supplements: Why high-dose curcumin is different from food
01:06:12 – “Taste and adjust”: The most important cooking step before serving
01:08:55 – Basil at the end & final flavour check
01:09:20 – Curry ready
01:12:50 – Dessert reveal: Chia pudding with cashews & mango
01:22:08 – Final thoughts - Show more
