Episodes
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I’m excited to welcome Dr. Dave Rabin today. Dr. Rabin is a translational neuroscientist and board-certified psychiatrist who specializes in treatment-resistant PTSD, addiction, vagus nerve activation, and HRV as a biomarker. He is also the author of A Simple Guide to Being Alive, a thoughtful and helpful guide to supporting our health, and one of my favorite books in the last several years.In this episode, we explore the habitat crisis and why we cannot bully our nervous system into safety. Dr. Rabin explains trauma and support, healing from within, the role of anhedonia, and why the absence of pleasure is a physiologic issue rather than a moral one. We also discuss wonder, awe, and play; the importance of touch, intimacy, eye contact, oxytocin, and co-regulation; the role of psychedelics, medication, and psychotherapy in trauma healing, and how kindness toward ourselves and others can help activate the vagus nerve.Stay tuned for an insightful discussion on supporting your nervous system, healing from within, and rethinking what it means to be truly alive.IN THIS EPISODE, YOU WILL LEARN: Why Dr. Rabin believes we are facing a habitat crisis rather than simply a mental health crisis What happens when you try to bully your nervous system into safety How the vagus nerve helps shift the body from chronic stress into recovery Being blamed or unsupported after hardship can reinforce a victim mindset. Why medicine, technology, practitioners, and other tools should help activate your own healing rather than become something you depend on Wonder, awe, play, and pleasure may support the body's natural healing response. How human connection, oxytocin, co-regulation, and shared experiences support nervous system regulation and recovery How psychedelic-assisted therapy fits into trauma healing How medication can help stabilize people while healing begins Why being kind to yourself is an essential part of healingBio: Dr. Davis RabinDr. David M. L. Rabin, MD, PhD, is a translational neuroscientist, psychiatrist, entrepreneur & inventor on a mission to cure mental illness. He has been studying the impact of chronic stress in humans for over 20 years, focusing on trauma, addiction, and human performance. Dr. Rabin is a Senior Research Scientist at the Institute for Human and Machine Cognition, the Chief Medical Officer and co-founder at Apollo Neuroscience, the Executive Director of The Board of Medicine Nonprofit Medical Board, and the Medical Director of The Apollo Clinic. In addition to hosting The Psychedelic Report and Your Brain Explained podcasts, Dr. Rabin regularly serves as an expert for news outlets such as The New York Times, Vogue, CBS News, The Washington Post, and The Wall Street Journal. In his spare time, he enjoys cooking, dancing, playing volleyball, sailing, and hiking with his wife, Kathryn, and their son, Sammy.Connect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia’s website. Submit your questions to [email protected] Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow. Purchase Cynthia’s book, The Menopause Gut. Cynthia’s Intermittent Fasting Transformation Book The Midlife Pause Supplement LineConnect with Dr. David Rabin On his website On social media: @DrDaveRabin The Psychedelic Report and Your Brain Explained Podcasts Dr. Rabin’s book: A Simple Guide to Being Alive
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I am happy to connect with Coach Bronson Dant today. He has spent over a decade guiding and training people in health and fitness. He discovered the benefits of a whole-food, animal-based ketogenic diet for optimizing metabolic health and performance, and wrote The Ultimate Ketogenic Fitness Book.
In our discussion today, we dive into the powerful story of Coach Bronson’s pain-to-purpose journey. We explore the value of mindset and look at how age-related changes affect muscle, inflammation, and metabolic flexibility. He shares his three pillars of muscle health related to nutrient density, bioavailability, and satiety, and we examine the importance of sleep, the impact of extremes in exercise, and the value of stress management. We also unravel the complexities of weight-loss resistance, and Coach Bronson discusses his research published in the Journal of Nutrition, Metabolism, and Health Science, sharing his perspective on macros and functional movement in menopausal women.
IN THIS EPISODE YOU WILL LEARN:
Coach Bronson shares his three pillars for nutrition
The limitations of basing nutrition on calories alone
How the hormone piece impacts effective weight management
How to avoid physical deterioration through fitness and nutrition
Why Coach Bronson advocates for living life to the fullest and dying quickly
How does muscle mass impact metabolic health?
The importance of taking a balanced approach to weight loss
How sleep aids muscle recovery and growth
Stress management, nutrition, and fitness for overall well-being
How alcohol affects our health and fitness
The benefits of combining functional movement training and proper nutrition for older adults
Connect with Cynthia Thurlow
Follow on X, Instagram & LinkedIn
Check out Cynthia’s website.
Submit your questions to [email protected]
Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow.
Purchase Cynthia’s book, The Menopause Gut.
Cynthia’s Intermittent Fasting Transformation Book
The Midlife Pause Supplement Line
Connect with Bronson Dant
On his website
YouTube and Instagram
The Ultimate Ketogenic Fitness Bundle -
Missing episodes?
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Today, I’m delighted to share a compilation of adrenal-centric discussions with experts Drs. Sonya Jensen, Carrie Jones, Scott Sherr, and Will Bulsiewicz, and geneticist Dr. Yael Joffe, Nurse Practitioner Heather Quaile, and Physician's Assistant McCall McPherson.
In this masterclass, we explore the effects of generational silence and how the thrifty genotype impacts the likelihood of poor metabolic health outcomes over time. We define the GABAergic system and the effects of decreased progesterone in perimenopause, and examine how our immune and nervous systems are impacted in midlife. We discuss the impact of GABA cofactors, the connection between adrenal and thyroid health, how stress affects ovarian aging, and the impact of genetics on our lifestyle choices and responses. We also unpack shift work and circadian rhythm disruption, and their influence on the gut microbiome.
Join us for today’s action - and information-packed, adrenal-centric podcast. I know you will enjoy listening to it as much as I enjoyed putting it all together.
IN THIS EPISODE, YOU WILL LEARN:
The impact of generational trauma on stress resilience and metabolic health across generations
How famine exposure, family history, and cultural background could contribute to our metabolic and hormonal health
How estrogen metabolism pathways can influence hormone balance and long-term health
The importance of B vitamins, magnesium, amino acids, protein, and overall nutritional status for healthy liver function and detoxification
How ongoing fight-or-flight activation can impair energy production and contribute to a cycle of worsening stress and fatigue
How hormones, sleep, toxins, infections, and insulin resistance can influence mitochondrial performance
The importance of optimizing thyroid and adrenal dysfunction together
How chronic stress and adverse childhood experiences can influence ovarian aging
How gut barrier dysfunction can contribute to chronic low-grade inflammation
How genetics and epigenetics can affect our appetite, hormone metabolism, mood, and treatment responses
Connect with Cynthia Thurlow
Follow on X, Instagram & LinkedIn
Check out Cynthia’s website
Submit your questions to [email protected]
Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow
Cynthia’s Menopause Gut Book is on presale now!
Cynthia’s Intermittent Fasting Transformation Book
The Midlife Pause Supplement Line
Connect with Dr. Sonya Jensen
On her book website: Heal Your Hormones, Reclaim Yourself
Instagram
Connect with Dr. Carrie Jones
On Instagram
Estrogen Detox Made Easy
Hello Hormones with Dr. Carrie Jones - Podcast
Connect with Dr. Scott Sherr
On his website
Troscriptions
Health Optimization Medicine
One Base Health
Connect with McCall McPherson
On Modern Thyroid Clinic
Instagram and TikTok
Modern Thyroid and Wellness Podcast
Thyroid Lab Guide
Connect with Heather Quaile
On her website
Instagram
Connect with Dr. Will Bulsiewicz
On his website
Connect with Yael Joffe
On 3X4 Genetics
Instagram
Facebook
Podcast Links:
Ep. 559 Heal Your Hormones, Reclaim Yourself: Women's Health in Midlife with Dr. Sonya Jensen | Perimenopause, Menopause & Hormones
Ep. 567 “Timing Is Everything” – The Best Way to Test Hormones, Cortisol & Thyroid for Real Answers with Dr. Carrie Jones
BONUS: "The Sympathetic Spiral of Doom!” – The Fastest Way To Reset Your Nervous System & End Burnout with Dr. Scott Sherr
Ep. 478 Thyroid Truths: Labs, Adrenals & Appetite Explained with McCall McPherson
Ep. 498 Chronic Stress Is Aging Your Ovaries – The Shocking Link Between Trauma, Hormones & Menopause with Heather Quaile
Ep. 537 The #1 Longevity Nutrient You’re Missing – How Fiber Supercharges Your Gut, Immunity & Sleep with Dr. Will Bulsiewicz
Ep. 558 Your DNA Isn’t Your Destiny – The Most Actionable Way to Use Genetics for Weight Loss with Dr. Yael Joffe -
Welcome to this week’s Midlife Minute.
In this episode, we’re focusing on progesterone, exploring the differences between progesterone and progestins, how progesterone is used in clinical practice, and how individual responses can vary significantly.
IN THIS EPISODE, YOU WILL LEARN:
Why bioidentical progesterone and synthetic progestins are not interchangeable
How early synthetic progestin studies continue to shape how progesterone is viewed
How different routes of progesterone administration produce different effects
Why do some women experience stronger neurological or physical effects than others on the same progesterone dose
How cyclical versus continuous use can affect how progesterone is used in the body
Why some women experience sleep or mood changes on oral progesterone
The importance of personalized decision-making
Connect with Cynthia Thurlow
Follow on X, Instagram & LinkedIn
Check out Cynthia’s website.
Submit your questions to [email protected]
Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow.
Purchase Cynthia’s book, The Menopause Gut.
Cynthia’s Intermittent Fasting Transformation Book
The Midlife Pause Supplement Line
Resources:
The pharmacodynamics and safety of progesterone doi:10.1016/j.bpobgyn.2020.06.002
Profiles of plasma estrogens, progesterone and their metabolites after oral or vaginal administration of estradiol or progesterone doi:10.1016/0378-5122(93)90064-O
Pharmacokinetics of progesterone and its metabolites allopregnanolone and pregnanolone after oral administration of low-dose progesterone doi:10.1016/j.maturitas.2005.11.005
Allopregnanolone and mood in the peripartum: a longitudinal assessment in healthy women doi:10.1016/j.psyneuen.2019.104465
Behavior of Male Gamete Fusogen GCS1/HAP2 and the Regulation in Arabidopsis Double Fertilization doi:10.3390/biom13020208
Tolerance to allopregnanolone with focus on the GABA receptor doi:10.1111/j.1476-5381.2010.01059.x
Effects of exercise training on the cardiovascular system: pharmacological approaches doi:10.1016/j.pharmthera.2007.03.010
Sex steroid induced negative mood may be explained by the paradoxical effect mediated by GABA modulators doi:10.1016/j.psyneuen.2009.02.003
Paradoxical effects of GABA modulators may explain sex steroid induced negative mood symptoms in some persons doi:10.1016/j.neuroscience.2011.03.061
Progesterone selectively increases amygdala reactivity in women doi:10.1038/sj.mp.4002030
Progesterone and allopregnanolone neuroprotective effects in the central nervous system doi:10.1016/S0006-8993(02)02366-5
Allopregnanolone and mood disorders doi:10.1016/j.pneurobio.2013.07.005
GABA receptor plasticity and neurosteroid cell withdrawal during the estrous cycle doi:10.1523/JNEUROSCI.2800-09.2009
Unequal risks for breast cancer associated with different hormone replacement therapies: results from the E3N cohort study doi:10.1007/s10549-007-9523-x
Management of Menopausal Symptoms: A Review doi:10.1001/jama.2022.24140
Progesterone vs. synthetic progestins and the risk of breast cancer: a systematic review and meta-analysis doi:10.1080/13697137.2018.1467611
Progesterone prevents sleep disturbances and modulates GH, TSH, and melatonin secretion in postmenopausal women doi:10.1210/jc.2010-2558 -
Today, I am thrilled to connect with a friend and colleague, Nat Niddam. Nat is a certified holistic nutritionist and epigenetic coach, and host of the Longevity with Nat Niddam podcast. She has one of the most engaged professional and public communities focused on peptide education and longevity protocols.
In today's discussion, we explain what peptides are and how they differ from HRT. We explore the differences between bioregulators and signaling peptides, clarify how peptides affect neurological and gut health, discuss beneficial peptides for muscle health and longevity, and examine the challenges surrounding peptide hype. We also explain why discernment is essential if you are considering peptides as part of a treatment plan with a licensed medical provider, and highlight specific topical peptides that can be helpful for aging skin.
I look forward to having Nat back to continue our conversation about peptide therapies.
IN THIS EPISODE, YOU WILL LEARN:
What are peptides?
How signaling peptides differ from bioregulators
Why it’s essential to work with a knowledgeable practitioner when considering peptides
Why sleep, hormones, stress levels, and gut health must be optimized before utilizing peptides
How peptides can support recovery, muscle maintenance, and heavy training periods
The importance of finding trustworthy practitioners and being skeptical of claims that sound too good to be true
Peptide compounds that can help people recover faster between workouts
Peptides and bioregulators that can support the immune system as we age
Topical peptides that can support collagen, elastin, wound healing, and skin repair
Bio: Nathalie Niddam
Nathalie Niddam, a holistic nutritionist and longevity educator, is dedicated to helping us all live joyful, vibrant lives well into our 50s, 60s, and beyond.
She shares strategies—from health tech to ancestral health, to peptides and more on her podcast, Longevity Podcast with Nathalie Niddam.
She speaks internationally, sharing her deep expertise on bioregulators—leading-edge compounds with the power to awaken the body's innate rejuvenation systems.
Connect with Cynthia Thurlow
Follow on X, Instagram & LinkedIn
Check out Cynthia’s website.
Submit your questions to [email protected]
Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow.
Purchase Cynthia’s book, The Menopause Gut.
Cynthia’s Intermittent Fasting Transformation Book
The Midlife Pause Supplement Line
Connect with Nathalie Niddam
On her website
Longevity with Nathalie Niddam (Podcast)
On Instagram -
I am honored to connect with Dr. Stacy Sims today. She is a forward-thinking international exercise physiologist and nutrition scientist on a mission to revolutionize exercise and nutrition performance- particularly for women.
In our conversation, we discussed the exclusion of women from research in the modern science era and how gender differences begin in utero. We look into the importance of tracking our menstrual cycles, the differences between follicular and luteal phases, and problematic ovulatory cycles, exploring the current research on oral contraceptives, the impact of the Women's Health Initiative, and the kind of training that is essential for women in perimenopause and menopause. We also cover the physiologic changes that occur in perimenopause and menopause, and Dr. Sims shares her thoughts on weight loss resistance, SECO, undereating, the importance of protein, and essential supplements for middle-aged women.
I know you will love this invaluable conversation with Dr. Stacy Sims.
IN THIS EPISODE YOU WILL LEARN:
Why are women still excluded from many studies?
How the physiological differences between men and women begin in utero and continue through adulthood
How stress during pregnancy affects the developing fetus
How the muscle morphology of women differs from that of men
Why girls need to learn new ways to move and build strength during puberty
How tracking menstrual cycle phases helps women optimize their training
The potential long-term effects of using oral contraceptives
Why a diverse diet is essential for supporting gut health
Common misconceptions surrounding hormone therapy
Why Dr. Sims recommends creatine for women in perimenopause and menopause
Connect with Cynthia Thurlow
Follow on X, Instagram & LinkedIn
Check out Cynthia’s website.
Submit your questions to [email protected]
Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow.
Purchase Cynthia’s book, The Menopause Gut.
Cynthia’s Intermittent Fasting Transformation Book
The Midlife Pause Supplement Line
Connect with Dr. Stacy Sims
On her website
Instagram
Facebook
TikTok -
Today, I am delighted to welcome Emily Sadri, a board-certified women’s health nurse practitioner and certified nurse-midwife, also trained in functional medicine. Emily is the founder of Aurelia Health, a private women’s health practice in the Van Aken district of Shaker Heights, Ohio, offering telehealth services specializing in hormone therapy and weight-loss support for women ages 35 to 55. As a leading hormone expert, she has built her practice around a hormones-first approach.
In today’s conversation, Emily explains the differences between being a nurse practitioner and a midwife, and we discuss nurse practitioner training, scope of practice, professional support, anticipatory guidance, and the limitations of conventional midlife care. Emily also shares why she prioritizes precision-oriented, personalized care, the value of Mira monitoring for precision hormone replacement therapy management in perimenopause, key hormonal changes she sees in early perimenopause, the impact of cyclic, static, and physiologic dosing of HRT, the influence of progestin IUDs, trends in healthcare, and less common reasons why women in midlife tend to become weight loss resistant.
Stay tuned for an insightful conversation on hormones, precision care, and supporting women through perimenopause and midlife.
IN THIS EPISODE, YOU WILL LEARN:
How women's health nurse practitioner training differs from midwifery, and how midwifery shaped Emily’s professional philosophy and ethics
Why women need to take ownership of their health throughout every life stage
The importance of moving beyond treating symptoms by using comprehensive lab work to identify broader hormonal and metabolic patterns
The value of using Mira, an at-home hormone monitoring system, to follow hormone patterns throughout an entire menstrual cycle, rather than relying on isolated laboratory measurements
Why Emily believes in looking at hormone patterns rather than progesterone decline or isolated estrogen levels when making hormone replacement therapy decisions
How static, cyclic, and physiologic HRT differ, and why Emily believes physiologic dosing deserves greater consideration.
Why treating hormones in isolation often fails to address the bigger picture, particularly during perimenopause
The importance of women being fully informed when considering hormonal birth control and intrauterine devices
Factors beyond sarcopenia, nutrition, sleep, and stress that could contribute to weight loss resistance
Bio: Emily Sadri
Emily Sadri is a Board Certified Women’s Health Nurse Practitioner, Certified Nurse Midwife, and hormone expert who founded Aurelia Health, a modern concierge telehealth company that serves women navigating perimenopause and menopause.
Emily's areas of expertise include metabolic health, precision hormone care, and longevity medicine. Her mission is to advance comprehensive care in midlife, create a model that fills in the gaps where primary care is failing women, and to recenter care around the relationship AS the medicine.
She resides in the Midwest with her husband, four children, and two dogs.
Connect with Cynthia Thurlow
Follow on X, Instagram & LinkedIn
Check out Cynthia’s website.
Submit your questions to [email protected]
Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow.
Purchase Cynthia’s book, The Menopause Gut.
Cynthia’s Intermittent Fasting Transformation Book
The Midlife Pause Supplement Line
Connect with Emily Sadri
On her website
Instagram
Aurelia Health -
Welcome to the latest Midlife Minute.
Today, we’re discussing how oral contraceptives and Depo Provera can impact women’s bone health over time.Stay tuned as I walk you through the research, prescribing trends, and ways women can support their bone health.
IN THIS EPISODE, YOU WILL LEARN:
How peak bone mass in adolescence affects bone health later in life
How oral contraceptives can interfere with the bone development of young women
The lack of informed conversations about the bone health risks associated with long-term contraceptive use
Why Depo Provera may have a stronger impact on bone density than oral contraceptives
The importance of nutrition and strength training for supporting bone health
How hormonal contraceptives can affect the gut microbiome and immune system
What you need to consider regarding your bone density and long-term health if you’ve been using oral contraceptives or Depo for many years
Connect with Cynthia Thurlow
Follow on X, Instagram & LinkedIn
Check out Cynthia’s website.
Submit your questions to [email protected]
Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow.
Purchase Cynthia’s book, The Menopause Gut.
Cynthia’s Intermittent Fasting Transformation Book
The Midlife Pause Supplement Line
Resources:
Depot medroxyprogesterone acetate, oral contraceptives and bone mineral density in a cohort of adolescent girls doi:10.1016/j.jadohealth.2004.07.005
Oral Contraceptive Use and Bone Density Change in Adolescent and Young Adult Women: A Prospective Study of Age, Hormone Dose, and Discontinuation doi:10.1210/jc.2010-3027
Adolescent use of combined hormonal contraception and peak bone mineral density accrual: A meta-analysis of international prospective controlled studies doi:10.1111/cen.13932
No need to specialize: reproductive health is for all adolescents doi:10.1016/j.jpag.2006.01.055
Injectable Hormone Contraception and Bone Density: Results from a Prospective Study doi:10.1097/00001648-200209000-00015
Hormonal contraception and the development of autoimmunity: A review of the literature doi:10.1080/00243639.2017.1360065
Oral contraceptives, reproductive factors and risk of inflammatory bowel disease doi:10.1136/gutjnl-2012-302362
Combined oral contraceptive use and the risk of systemic lupus erythematosus doi:10.1002/art.24398
Oral Contraceptives and Multiple Sclerosis/Clinically Isolated Syndrome Susceptibility doi:10.1371/journal.pone.0149094
The Experience of Surviving a High-Risk Pregnancy doi:10.1080/23293691.2016.1166104
Effects of 0.9 mg Recombinant Human Thyrotropin on Thyroid Size and Function in Normal Subjects: A Randomized, Double-Blind, Cross-Over Trial doi:10.1210/jc.2004-0914
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Today, I’m delighted to welcome Craig Emmerich as my guest. He's an electrical engineer and bestselling author who works closely with his wonderful wife, Maria. Craig has been following a keto diet for over 17 years and a carnivore diet for over six years to help him overcome chronic Lyme disease and inflammatory response syndrome. Focusing on the science of human nutrition, he has helped thousands of clients regain their health and vitality.
In today’s discussion, we explore the principles of metabolic health, the role of ultra-processed foods, the bliss point, and the loss of nutrient density. We examine midlife changes in metabolic health and body composition, and highlight the critical importance of metabolic flexibility and adequate protein intake. Craig clarifies why body composition should be considered rather than the scale and explains how he determines carbohydrate tolerance. We also examine the research on the gut microbiome, the insulin-fat cell relationship, insulin resistance, fasting, and the protein-sparing modified fast as strategies for weight loss, and discuss leptin resistance, alcohol, the effects of cortisol and sleep on the hormone cascade, and troubleshooting women’s midlife challenges around HRT, hydration, electrolytes, and body composition shifts.
Stay tuned for today’s informative discussion with Craig Emmerich, who has recently launched a new book, The Art of Metabolic Health, that he and his wife co-authored.
IN THIS EPISODE, YOU WILL LEARN:
The importance of consuming whole foods and prioritizing your protein intake
How companies engineer foods to encourage overeating
Why body composition matters more than the number on the scale
How building and maintaining muscle helps to improve insulin sensitivity and metabolic health
Why adequate protein intake is essential for maintaining and improving bone density
How your carbohydrate intake should be tailored to suit your personal goals, health status, and your response to different foods
How insulin resistance develops
Why alcohol can interfere with fat loss efforts
How inadequate sleep can worsen insulin resistance
Bio: Craig Emmerich
Craig Emmerich, who graduated in Electrical Engineering, has spent the last 16-plus years researching nutrition and working with thousands of clients alongside his wife, Maria Emmerich. He is an international bestselling author of “Keto: The Complete Guide” and “The Carnivore Cookbook”. He uses his knowledge of how our bodies work to help clients heal and lose weight, leveraging their biology to make it easier.
Craig has helped hundreds of thousands of people regain their health and vitality with a strong focus on the science of human nutrition.
Craig has been keto for over 17 years and carnivore for over 6 years to help treat his chronic Lyme disease and CIRS pain.
Connect with Cynthia Thurlow
Follow on X, Instagram & LinkedIn
Check out Cynthia’s website.
Submit your questions to [email protected]
Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow.
Purchase Cynthia’s book, The Menopause Gut.
Cynthia’s Intermittent Fasting Transformation Book
The Midlife Pause Supplement Line
Connect with Craig Emmerich
On his website -
I am delighted to have Dr. Ken Berry returning to the podcast for his fourth appearance today. He is a physician, bestselling author, and passionate advocate for health, known for his no-nonsense approach to wellness. Dr. Berry has practiced at the Berry Clinic since 2003 and is an active community member. He has a YouTube channel with more than 2 million subscribers- one of my favorite go-to resources for patients.
In our discussion today, we explore a recent Time news article and the growing concerns around the declining trustworthiness of media sources. We dive into the limitations of observational research, the problem with celebrity endorsements of ultra-processed foods, rising obesity rates in children and teens, and whether genetic factors are actually behind obesity, as highlighted recently in a 60 Minutes segment. We also discuss the impact of sugar, grains, and seed oils, as well as the significance of visceral fat.
You will not want to miss this invaluable discussion with Dr. Ken Berry.
IN THIS EPISODE YOU WILL LEARN:
Dr. Berry breaks down some deeper issues surrounding the recent Time article, where a lone registered dietitian claimed that ultra-processed foods are acceptable.
How media sources are losing their credibility
The vital part social media plays in changing the narrative and holding media sources accountable
Why consumers must stay informed and be proactive in their health choices
The health implications of eating ultra-processed foods
Dr. Berry shares his concerns about the American Academy of Pediatrics recommending drugs like Ozempic for children.
The benefits of eating whole foods
Dr. Berry shares his three rules for a healthy diet.
Why we need to avoid sugar and seed oils
How following a low-carb diet can help reduce visceral fat.
Dr. Berry introduces the American Diabetes Society and explains its mission.
Bio:
Dr. Ken D. Berry, MD, is a licensed family physician, best-selling author, and leading advocate for the Proper Human Diet (PHD). With over two decades of clinical experience, Dr. Berry specializes in helping patients improve their health through low-carbohydrate, nutrient-dense eating. His best-selling book, "Lies My Doctor Told Me: Medical Myths That Can Harm Your Health," and his popular YouTube channel, which has over 3 million subscribers, provide accessible, evidence-based guidance on nutrition and wellness. Dr. Berry's mission is to empower individuals to reclaim their health by debunking common medical myths and promoting sustainable dietary and lifestyle changes. He is also a member of the Diet Doctor low-carb expert panel and an active participant in the keto and low-carb communities. Dr. Berry lives with his wife Neisha and their children on a farm in Holladay, Tennessee.
Connect with Cynthia Thurlow
Follow on X, Instagram & LinkedIn
Check out Cynthia’s website.
Submit your questions to [email protected]
Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow.
Purchase Cynthia’s book, The Menopause Gut.
Cynthia’s Intermittent Fasting Transformation Book
The Midlife Pause Supplement Line
Connect with Dr. Ken Berry
On his website
YouTube
Dr. Berry’s Books
The American Diabetes Society -
I’m delighted to connect with Dr. Catherine Clinton today. She’s a licensed naturopathic physician, author, and the Founder and Chair of the Quantum Biology Health Institute. With over 18 years of clinical and educational experience, she helps wellness seekers and healthcare practitioners understand health through a systems-based, quantum biology lens. Her work is dedicated to expanding our understanding of health by honoring the body’s intelligence and its relationship with light, water, and the environment.
In today’s conversation, Dr. Clinton explains what quantum biology is and how light shapes circadian rhythms and hormone balance. We discuss the emerging science of structured water, grounding, fascia, mitochondrial health, and the gut's energetic environment, also exploring practical ways to support your health by paying attention to your body's relationship with its surroundings.
Join us for a truly fascinating discussion on how light, water, energy, and environment can influence our health in ways we have never even considered.
IN THIS EPISODE, YOU WILL LEARN:
How quantum biology differs from conventional biology
Why is natural morning light so important for our bodies?
The disruptive effects of LED lighting
Dr. Clinton explains what structured water is and the important role it may play in cellular function.
How healthy mitochondria support cellular energy production, hydration, overall health, and longevity
In addition to producing ATP, how the mitochondria can contribute to cellular hydration
How the minerals in drinking water can help the water move into and around cells
The value of grounding to support the electrical systems within the body
Why fascia is increasingly viewed as an active communication network within the body
Bio: Dr. Catherine Clinton
Dr. Catherine Clinton, ND, is a licensed naturopathic physician, author, and the Founder and Chair of the Quantum Biology Health Institute. With more than 18 years of clinical and educational experience, she helps wellness seekers and healthcare practitioners understand health through a systems-based, quantum biology lens.
While in naturopathic medical school, her diagnosis of two autoimmune conditions and Lyme disease reshaped her understanding of healing and led her beyond conventional models.
Dr. Clinton has published in peer-reviewed scientific journals, teaches internationally, and maintains a small clinical practice in Eugene, Oregon. Her work is dedicated to expanding our understanding of health by honoring the body’s intelligence and its relationship with light, water, and the environment.
Connect with Cynthia Thurlow
Follow on X, Instagram & LinkedIn
Check out Cynthia’s website.
Submit your questions to [email protected]
Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow.
Purchase Cynthia’s book, The Menopause Gut.
Cynthia’s Intermittent Fasting Transformation Book
The Midlife Pause Supplement Line
Connect with Dr. Catherine Clinton
On her website
Order a copy of Dr. Clinton’s book, Optimize, and get free bonuses -
Welcome to the latest Midlife Minute.
Today, we’re exploring the benefits of creatine monohydrate, essential aminos, grass-fed beef liver, and Yolked (fortotropin). I explain how these products work together, the importance of resistance training and hormone optimization as foundational factors in midlife, and how supplements fit in.
IN THIS EPISODE, YOU WILL LEARN:
The benefits of using creatine monohydrate when training
The value of essential aminos for muscle protein synthesis and reducing protein breakdown
The nutrients provided by grass-fed beef liver
What research suggests about how Yolked may relate to myostatin modulation, muscle hypertrophy pathways, and growth factor signaling
Why I recommend using creatine, essential aminos, beef liver, and Yolked together as a stacked approach
Why resistance exercise remains the primary signal for muscle growth
The importance of hormone optimization for energy, muscle building, executive function, motivation, and recovery
Connect with Cynthia Thurlow
Follow on X, Instagram & LinkedIn
Check out Cynthia’s website.
Submit your questions to [email protected]
Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow.
Purchase Cynthia’s book, The Menopause Gut.
Cynthia’s Intermittent Fasting Transformation Book
The Midlife Pause Supplement Line
Resources:
Visit getkion.com/cynthia for 20% off.
Yolked: Use the code CYNTHIA for 20% off
Ancestral Supplements: Use the affiliate code CYNTHIA -
Today, I am thrilled to connect with Dr. Linda Bluestein, a board-certified anesthesiologist and integrative pain medicine physician specializing in Ehlers-Danlos Syndrome, hypermobility spectrum disorders, and related conditions, including POTS, mast cell activation, and chronic pain.
In our discussion, we discuss the invisible illness problem and complex medical illnesses, and Dr. Bluestein shares how being diagnosed with EDS in her 40s prompted her to pivot her career to focus on what is missing in medicine regarding those complex illnesses. We explore different types of hypermobility conditions and why women are disproportionately more affected by those conditions than men. We clarify what hypermobility means, the cluster of EDS, POTS, and MCAS, what to do when you have unexplained multi-system symptoms, and how AI can be beneficial. We also examine pain science, hypermobility, sympathetic overdrive, kinesiophobia, anesthesia considerations in connective tissue disorders, and the impact of midlife transitions, HRT, medical gaslighting, nervous system regulation, movement, nutrition, and validation and hope for patients with complex medical illnesses.
I am delighted to share this informative conversation with Dr. Linda Bluestein with the Everyday Wellness community, and look forward to having Dr. Bluestein back to explore this topic further.
IN THIS EPISODE, YOU WILL LEARN:
How patients with complex symptoms often go from specialist to specialist, yet none of them connect the dots.
How patients tend to be blamed when treatments fail
How POTS diagnosis is often based on heart rate changes, even though it’s not primarily a heart rate condition
How dysautonomia affects multiple body systems
How, apart from joint flexibility, hypermobility can also involve skin, tissues, organs, and multiple body systems.
How EDS, POTS, and MCAS can overlap
The value of AI tools for helping patients organize complex symptom histories
How sympathetic overdrive and kinesiophobia can worsen chronic pain
The impact of medical gaslighting
Bio: Dr. Linda Bluestein
Dr. Linda Bluestein is a board-certified anesthesiologist and integrative pain medicine physician who specializes in Ehlers-Danlos Syndromes, hypermobility spectrum disorders, and related conditions, such as POTS, mast cell activation, and chronic pain.
She is the founder of Hypermobility MD and the host of the internationally recognized Bendy Bodies Podcast, where she bridges the gap between patients and clinicians by unpacking complex medicine through a pattern-based, whole-person lens. Dr. Bluestein is also an EDS patient herself, bringing both clinical expertise and lived experience to conversations about diagnostic delays, medical gaslighting, and compassionate, effective care.
Connect with Cynthia Thurlow
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Submit your questions to [email protected]
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Purchase Cynthia’s book, The Menopause Gut.
Cynthia’s Intermittent Fasting Transformation Book
The Midlife Pause Supplement Line
Connect with Dr. Linda Bluestein
Bendy Bodies Podcast
Dysautonomia Support Network -
I am delighted to have the privilege of reconnecting with Dr. Deb Matthew today. She joined me once before on Episode 259. She is a distinguished best-selling author, international speaker, and dedicated educator known as the Happy Hormone Doctor.
Cardiovascular disease is the number one killer of women in the United States, causing one of every 3.2 deaths among women annually. In our conversation today, Dr. Matthew and I delve into the realm of cardiovascular disease, exploring the benefits of hormone replacement therapy, essential laboratory testing, medications, and the neurocognitive changes that occur during perimenopause and menopause. We also focus on lifestyle, gut testing, and the all-time favorite topic: weight-loss resistance.
Stay tuned for today’s engaging, enriching, and enlightening discussion with Dr. Deb Matthew.
IN THIS EPISODE YOU WILL LEARN:
How HRT reduces the risk of cardiovascular disease
How long-term use of estrogen can reduce the risk of heart disease over time
Why you should do a hormone panel before starting HRT
How cortisol levels impact cardiovascular health
How the coronary calcium score helps to predict heart attack risk
Cholesterol markers and their significance in cardiovascular risk assessment
Managing cholesterol levels in perimenopausal women
The importance of addressing underlying hormonal imbalances in women to mitigate cognitive decline and lipid disorders
The connection between gut health and brain fog
How women’s testosterone levels impact their cognition and motivation
Hormone imbalance and weight loss resistance in women
Connect with Cynthia Thurlow
Follow on X, Instagram & LinkedIn
Check out Cynthia’s website.
Submit your questions to [email protected]
Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow.
Purchase Cynthia’s book, The Menopause Gut.
Cynthia’s Intermittent Fasting Transformation Book
The Midlife Pause Supplement Line
Connect with Dr. Deb Matthew
On her website
Facebook
Instagram
Dr. Deb Matthew’s book This is Not Normal on Amazon
Previous Episode featuring Dr. Matthew
Ep. 295: HRT’s Impact on Women’s Health Through Time with Dr. Deb Matthew -
I am honored to connect with Dr. Navaz Habib today. He is the Vagus Nerve Doc, a bestselling author, and host of the Health Upgrade podcast.
In our discussion today, we look at what it takes to upgrade the vagus nerve, exploring how it is regulated, the role of vagal tone, and how it can be damaged with chronic stress. We examine the impact of allostatic load and dysregulation, and how midlife physiology compels us to proactively address our vagal tone. We cover the impact of acetylcholine and other neurotransmitters, and why key nutrients like choline and omega-3s are necessary for proper vagal tone, and we dive into hormetic stressors and safety, how HRV and vagal tone are assessed, and targeted strategies to enhance vagus nerve performance. Dr. Habib also discusses his Vagus Program, which provides tools to improve vagal tone.
Stay tuned for this informative conversation with Dr. Habib. I look forward to inviting him back to continue the discussion.
IN THIS EPISODE, YOU WILL LEARN:
Dr. Habib describes the vagus nerve as the brake system of the autonomic nervous system, and explains how it connects to most major organs, working as a central communication highway
What vagal tone is
Dr. Habib frames allostatic load in the context of a combined stress burden
How “little t” trauma influences vagus nerve function and creates stress response patterns later in life
Why midlife can be a period of increased stress sensitivity and autonomic dysregulation
The key biochemical drivers of vagus nerve signaling and immune regulation
How diaphragmatic breathing can directly influence vagus nerve activity
What HRV actually measures, and how to interpret it correctly
A practical framework of small interventions to build long-term autonomic flexibility
Bio: Dr. Navaz Habib
Dr. Navaz Habib, aka "The Vagus Nerve Doc," is a best-selling author of 2 books - “Activate Your Vagus Nerve” and “Upgrade Your Vagus Nerve” and host of The Health Upgrade Podcast.
After using functional medicine to overcome his own health challenges, Dr. Habib built Health Upgraded, an online health program implementing his VAGUS protocol, to guide parents and professionals to enhance their health by unlocking the healing power of the Vagus nerve to reduce the effects of stress and inflammation.
Connect with Cynthia Thurlow
Follow on X, Instagram & LinkedIn
Check out Cynthia’s website.
Submit your questions to [email protected]
Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow.
Purchase Cynthia’s book, The Menopause Gut.
Cynthia’s Intermittent Fasting Transformation Book
The Midlife Pause Supplement Line
Connect with Dr. Navaz Habib
On Instagram
The Vagus Nerve Doc on YouTube
Learn more about Dr. Habib’s Vagus Protocol and become part of the online community.
Dr. Habib’s books: Activate Your Vagus Nerve and Upgrade Your Vagus Nerve -
Welcome to the latest Midlife Minute.Today, I’m taking a closer look at oral contraceptive use in perimenopause and menopause, exploring how oral contraceptives work, how they suppress or blunt perimenopausal and menopausal symptoms, alter hormone signaling and testing, what women may experience when they stop taking them, and why the gut microbiome is an essential part of the conversation.IN THIS EPISODE, YOU WILL LEARN: How oral contraceptives suppress certain key signaling hormones, making it difficult to assess women’s menopausal status accurately What women may experience when transitioning off oral contraceptives How long-term oral contraceptive use can alter gut microbial function and inflammatory pathways The association between long-term oral contraceptive use and nutrient depletion Why the standard reproductive hormone markers used to assess menopause (especially FSH/LH) are unreliable while on the pill How the microbiome changes that occur as women age may compound the effects of previous oral contraceptive use Helpful dietary, microbiome, and lifestyle strategies to support women navigating the post-pill transitionConnect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia’s website. Submit your questions to [email protected] Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow. Purchase Cynthia’s book, The Menopause Gut. Cynthia’s Intermittent Fasting Transformation Book The Midlife Pause Supplement LineResources: Sitruk-Ware R, Nath A. Characteristics and metabolic effects of estrogen and progestins contained in oral contraceptive pills. Best Practice and Research: Clinical Endocrinology and Metabolism. 2013;27(1):13–24. doi:10.1016/j.beem.2012.09.004 Schaffir J, Worly BL, Gur TL. Combined hormonal contraception and its effects on mood: a critical review. European Journal of Contraception and Reproductive Health Care. 2016;21(5):347–355. doi:10.1080/13625187.2016.1217327 Panzer C, Wise S, Fantini G, Kang D, Munarriz R, Guay A, Goldstein I. Impact of oral contraceptives on sex hormone-binding globulin and androgen levels: a retrospective study in women with sexual dysfunction. Journal of Sexual Medicine. 2006;3(1):104–113. doi:10.1111/j.1743-6109.2005.00198.x Palmery M, Saraceno A, Vaiarelli A, Carlomagno G. Oral contraceptives and changes in nutritional requirements. European Review for Medical and Pharmacological Sciences. 2013;17(13):1804–1813. PMID:23852908 Khalili H, Higuchi LM, Ananthakrishnan AN, Richter JM, Feskanich D, Fuchs CS, Chan AT. Oral contraceptives, reproductive factors and risk of inflammatory bowel disease. Gut. 2013;62(8):1153–1159. doi:10.1136/gutjnl-2012-302362 Flores R, Shi J, Fuhrman B, Xu X, Veenstra TD, Gail MH, Gajer P, Ravel J, Goedert JJ. Fecal microbial determinants of fecal and systemic estrogens and estrogen metabolites: a cross-sectional study. Journal of Translational Medicine. 2012;10:253. doi:10.1186/1479-5876-10-253 Baker JM, Al-Nakkash L, Herbst-Kralovetz MM. Estrogen-gut microbiome axis: physiological and clinical implications. Maturitas. 2017;103:45–53. doi:10.1016/j.maturitas.2017.06.025 Hua X, Cao Y, Morgan DM, Miller K, Chin SM, Bellavance D, Khalili H. Longitudinal analysis of the impact of oral contraceptive use on the gut microbiome. Journal of Medical Microbiology. 2022;71(4):001512. doi:10.1099/jmm.0.001512 Mihajlovic J, Leutner M, Hausmann B, Kohl G, Schwarz J, et al. Combined hormonal contraceptives are associated with minor changes in composition and diversity in gut microbiota of healthy women. Environmental Microbiology. 2021;23(6):3037–3047. doi:10.1111/1462-2920.15461 Seelig MS. Increased magnesium need with use of combined oestrogen and calcium supplementation. Magnesium Research. 1990;3(3):197–215. PMID:2133742 Donders GGG, Bellen G, Mendling W. Management of recurrent vulvo-vaginal candidosis as a chronic illness. Gynecologic and Obstetric Investigation. 2010;70(4):306–321. doi:10.1159/000314022 Krog MC, Hugerth LW, Fransson E, et al. The healthy female microbiome across body sites: effect of hormonal contraceptives and the menstrual cycle. Human Reproduction. 2022;37(7):1525–1543. doi:10.1093/humrep/deac094
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Today, I’m thrilled to connect with Rowan Jacobsen. Rowan writes about science, nature, and the world’s lesser-explored corners for publications including Harper’s, Outside, The Atlantic, Scientific American, Smithsonian, and The New York Times, among others. He is the author of nine books, has lectured at Harvard and Yale, and has appeared on CBS, NBC, and NPR.
In today’s conversation, we discuss his unique and fascinating new book, In Defense of Sunlight, which explores the nuances surrounding light exposure. We look at the value of sun exposure and vitamin D, and Rowan explains why light acts as a master regulator in the body and how our modern lifestyles may be disrupting our natural biology more than we realize. We examine the effects of shift work, cortisol rhythm dysregulation, and the minimum effective dose of sunlight intensity and exposure, and Rowan breaks down how UVA and UVB wavelengths impact our physiology. We also cover the importance of nitric oxide production, and Rowan shares recommendations from his work.
Stay tuned for an eye-opening conversation on why sunlight may be one of the most overlooked foundations of human health. For those who enjoy reading about science, I highly recommend Rowan’s book!
IN THIS EPISODE, YOU WILL LEARN:
Why so many people fear any sun exposure rather than aiming for sensible, moderate exposure
How light acts as a master regulator for circadian biology
Why does spending most of the day indoors with artificial lighting make it harder to maintain healthy circadian rhythms?
How shift work disrupts the body’s normal repair processes
How cortisol and melatonin work together as part of a coordinated daily rhythm
What research shows about cloudy outdoor environments providing higher light levels than most indoor spaces
The differences between how UVA and UVB exposure impact the body
How ultraviolet light can trigger nitric oxide release
Practical ways to support your circadian health
Connect with Cynthia Thurlow
Follow on X, Instagram & LinkedIn
Check out Cynthia’s website.
Submit your questions to [email protected]
Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow.
Purchase Cynthia’s book, The Menopause Gut.
Cynthia’s Intermittent Fasting Transformation Book
The Midlife Pause Supplement Line
Connect with Rowan Jacobsen
On his website
Rowan’s book, In Defense of Sunlight, will be available online and in bookstores on June 16th -
I had the honor of reconnecting with Chris Irvin today! (He was with me once before, on Episode 175.)Chris is a nutrition researcher, writer, and educator specializing in low-carb dieting for metabolic health and human performance. He is the author of Keto Answers, The Carnivore Diet for Beginners, and Mommy, Do I Have to Eat This? He is also the Chief Marketing Officer at BioCoach, a company dedicated to taking down prediabetes and diabetes.Chris is an incredible resource on the value of keto and low-carb diets! His book, Keto Answers, is one of my favorite keto resources to recommend to clients! In this episode, Chris and I discuss the differences between micro- and macronutrients. We talk about the therapeutic uses of keto, low-carb, hormesis, and carnivore diets; the role of metabolic health; the value of protein; balancing longevity and sarcopenia; and the results of over-fasting, over-restricting, and creating too much stress on the body. We also dive into questions from listeners about the impact of low-carb and ketogenic diets on cholesterol panels and endurance, how to troubleshoot digestive distress, protein excess, and Chris’s favorite gadgets and supplements. I hope you enjoy listening to this podcast as much as I did recording it! Stay tuned for more!IN THIS EPISODE YOU WILL LEARN: The therapeutic benefits of keto, carnivore, low-carb diets, and fasting. The value of protein. How much protein should you eat? The importance of having muscle. The benefits of eating grass-fed red meat. The problem with over-restricting, over-exercising, and over-fasting. Changing things up occasionally and using reverse dieting for optimum health. Adding more protein to your diet will make you feel better, and you won't gain weight. How will a low-carb or keto diet impact your overall cholesterol? Chris explains how a low-carb or keto diet affects the performance of endurance athletes. Products you can use to optimize endurance performance. Chris explains why digestive distress could occur with keto and shares his recommendations for overcoming it. The impact of a low-carb diet on thyroid function.Connect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia’s website. Submit your questions to [email protected] Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow. Purchase Cynthia’s book, The Menopause Gut. Cynthia’s Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Connect with Chris Irvin On his website On Facebook, Instagram, and Twitter: https://twitter.com/TheKetologist Thinking Health Newsletter The Keto Answers Podcast
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Today, I am delighted to reconnect with Dr. William Davis. He’s a cardiologist, New York Times bestselling author of the Wheat Belly book series, and author of Super Gut. He is also the founder and Medical Director of the Infinite Health Program and the co-founder and Chief Medical Officer of Realize Therapeutics Corp, which is developing innovative solutions to restore and support the human microbiome.
In our conversation, we explore the microbiome and how it is influenced by key changes in a woman’s life, including pregnancy and premature delivery, as well as how modern lifestyle factors disrupt our microbiome. Dr. Davis discusses endotoxemia and dysbiosis in fertility, uterine health, and cardiovascular disease, as well as antibiotic use, statins, atrial fibrillation, the role of blood glycocalyx, TMAO, and the dietary approach he considers important. He also discusses appropriate prescribed antibiotic use in the context of microbiome disruption.
Stay tuned for another fascinating discussion with Dr William Davis on the far-reaching impact of the microbiome on women's health, heart health, and longevity. I look forward to having Dr. Davis back on the show!
IN THIS EPISODE, YOU WILL LEARN:
How factors such as omega-3 fatty acid intake and microbiome health may affect pregnancy outcomes.
How microbial health extends beyond the gastrointestinal tract and can influence multiple organ systems
The disruptive effects of antibiotics, glyphosate, food preservatives, and emulsifiers on the microbiome
Dr. Davis describes how endotoxemia can affect the brain, skin, joints, metabolism, and cardiovascular system.
How endotoxemia influences multiple cardiovascular risk markers
How endotoxemia and glycation can contribute to atrial fibrillation
The role of the glycocalyx, and how damage to the integrity of the glycocalyx could influence arterial function and cardiovascular risk
Why fermented foods remain a key strategy for microbiome diversity
Dr. Davis shares his dietary choices and his approach to microbiome support
Bio: William Davis, MD
William Davis, MD, is a cardiologist and #1 New York Times bestselling author of the Wheat Belly series of books, as well as Undoctored and Super Gut.
Recent human clinical trials that Dr. Davis conducted have revealed that it is possible to lose fat weight while preserving muscle, thereby preventing weight regain and enjoying improved body composition, findings that inspired the writing of Bulge.
Dr. Davis is also Chief Medical Officer at Realize Therapeutics Corp., which he co-founded to explore the new science of the microbiome to improve health and appearance, including body composition.
Connect with Cynthia Thurlow
Follow on X, Instagram & LinkedIn
Check out Cynthia’s website.
Submit your questions to [email protected]
Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow.
Purchase Cynthia’s book, The Menopause Gut.
Cynthia’s Intermittent Fasting Transformation Book
The Midlife Pause Supplement Line
Connect with Dr. William Davis
On his website
Join Dr Davis’s Inner Circle
Dr. Davis’s books -
Welcome to this week’s Midlife Minute.Today, I’m focusing on all the questions I received about gallbladder health, including HRT-provoking symptoms, supplements that improve gallbladder health, and evidence-based food interventions.IN THIS EPISODE, YOU WILL LEARN: Why the risk of gallstones and gallbladder inflammation increases during the menopause transition How estrogen and progesterone HRT have different effects on gallbladder functioning The differences in risk between transdermal and oral HRT How the progesterone in HRT can cause gallbladder issues in some women What TUDCA is, and how it supports gallbladder health The value of TUDCA for women who have had their gallbladders removed How various nutrients and supplements support bile flow and gallbladder health What can contribute to gallstone formationConnect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia’s website. Submit your questions to [email protected] Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow. Purchase Cynthia’s book, The Menopause Gut. Cynthia’s Intermittent Fasting Transformation Book The Midlife Pause Supplement LineGallbladder Research: Cabrera D, Arab JP, Arrese M. UDCA, NorUDCA, and TUDCA in liver diseases: a review of their mechanisms of action and clinical applications. Seminars in Liver Disease. 2019;39(4):397–404. doi:10.1055/s-0039-1696799 Vang S, Longley K, Steer CJ, Low WC. The unexpected uses of urso- and tauroursodeoxycholic acid in the treatment of non-liver diseases. Global Advances in Health and Medicine. 2014;3(3):58–69. doi:10.7453/gahmj.2014.017 Bai M, Yang L, Liao H, et al. Tauroursodeoxycholic acid improves nonalcoholic fatty liver disease by regulating gut microbiota and bile acid metabolism. Journal of Agricultural and Food Chemistry. 2024;72(41):22655–22668. doi:10.1021/acs.jafc.4c04630 Simon JA, Hudes ES. Relation of serum ascorbic acid to serum vitamin B12, serum ferritin, and kidney stones in US adults. *Archives of Internal Medicine.*1999;159(6):619–624. doi:10.1001/archinte.159.6.619 Walcher T, Haenle MM, Kron M, et al. Vitamin C supplement use may protect against gallstones: an observational study on a randomly selected population. BMC Gastroenterology. 2009;9:74. doi:10.1186/1471-230X-9-74 Tsai CJ, Leitzmann MF, Willett WC, Giovannucci EL. Long-term intake of dietary fiber and decreased risk of cholecystectomy in women. American Journal of Gastroenterology. 2004;99(7):1364–1370. doi:10.1111/j.1572-0241.2004.30281.x Leitzmann MF, Stampfer MJ, Willett WC, Spiegelman D, Colditz GA, Giovannucci EL. Coffee intake is associated with lower risk of symptomatic gallstone disease in women. Gastroenterology. 2002;123(6):1823–1830. doi:10.1053/gast.2002.37085 Moerman CJ, Smeets FW, Kromhout D. Dietary risk factors for clinically diagnosed gallstones in middle-aged men — a 25-year follow-up study. Annals of Epidemiology. 1994;4(3):248–254. doi:10.1016/1047-2797(94)90099-x Association between dietary magnesium intake and gallstones: the mediating role of atherogenic index of plasma. Lipids in Health and Disease. 2024;23(1):82. doi:10.1186/s12944-024-02074-4 Pitt HA, Doty JE, Murphy MM, Schwarz MB. Progesterone alters biliary flow dynamics. Annals of Surgery. 1999;229(2):205–209. doi:10.1097/00000658-199902000-00008
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