Episoder
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There's nothing new under the sun... except for these new antifungals which we will now educate you on!
One's an inhaled azole (OK not that new)One's sort of an echinocandin (shut up)Two are unpronounceable (but related to fungicides which we're using already)And Alyssa and Jame are joined by Dr Neil Stone, ID:IOTS Podcast Novel Antifungal Agent Correspondent, to guide you through it all!
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Callum was recently on the Primary Care Knowledge Boost podcast (https://pckb.org/), talking about what happens to microbiology specimens sent in to the lab. He did so well we thought we'd share it with you here! Enjoy...
Original podcast blurb here:
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Doctors Lisa and Sara are joined by Medical microbiology and Infectious Diseases Consultant Dr Callum Mutch to follow the journey of a urine sample and a throat swab as they are processed. We discuss the important points to get right in the pre-analytical, analytical and post analytical stages of their journeys. Some fascinating insights (including how the clinical details can affect what is tested for) that have changed our practice for the better.
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Manglende episoder?
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Process your Polyene Prescribing Paralysis by partaking in this proliferous podcast pondering on the particulars of these P-harmacological agents.*
*Alyssa had no part in the making of this podcast description.
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Prep notes for completed episodes can be found here (Not all episodes have prep notes).
If you are enjoying the podcast please leave a review on your preferred podcast app! -
Jame and Callum are joined by Christina Petridou. In this episode we give you an overview of ticks and the key infections they transmit..., but NOT Lyme disease.
Some of the infections we DO cover include: Rickettsiosis (spotted fever group), relapsing fevers, anaplasmosis, ehrlichiosis, babesiosis, TBE & CCHF.
Not Lyme. THIS IS NOT A LYME DISEASE EPISODE.
Show notes (including lots of summary tables and horrible tick pics) for this episode are here.
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If you are enjoying the podcast please leave a review on your preferred podcast app! -
Flucytosine. A much maligned antifungal, consigned to adjuvant use in Cryptococcus...
WELL THAT CHANGES... well not today because the resistance barrier is shockingly low, but at least in 20m time you'll know all you need to about 5-FC!
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Lab containment levels 1-4Safety cabinets 1-3ACDP approved list of biological agents 2-4Counterterrorism act schedule 5 pathogensCat A and Cat B transport SAPO?!
Confused? We're not surprised, but things will all become clear.... Once you listen to this masterclass from Dr Claire Gordon on all things biosafety and biosecurity from a UK lab perspective.
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If you are enjoying the podcast please leave a review on your preferred podcast app! -
What could be more Rare Imported or Pathogenic than the Viral Haemorrhagic fevers?!
Callum is joined again by Drs Claire Gordon and Amy Bellfield to talk all things VHF and HCID from the clinical lab perspective.
We're sure you'll all be Very Happy Fans by the end of this one...
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Terbinafine! Griseofulvin!
2 weird antifungals that the dermatologists use much more than us!
But we here at the ID:IOTS Podcast love all our antifungal agents equally so here's an episode on literally everything you need to know about both these agents!
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If you are enjoying the podcast please leave a review on your preferred podcast app! -
Now this an episode, first of a triple
About all the work of a lab called RIPL
And we'd like to take minute now so sit right here
And learn about all the horrible pathogens you now should fear
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If you are enjoying the podcast please leave a review on your preferred podcast app! -
Part 2 of 2 on Echinocandins!
Tihana Bicanic gives a masterclass on Rezafungin, its use now and in the future, and gives an update on the relevant clinical trials and studies you need to know to make you a Master Echinocandologist.
Alyssa and Jame are here too, but very much in receive-only mode. Listen in and find out why!
Notes for this episode are found here: https://idiots.notion.site/132-133-Echinocandins-2d76a1ea09d8811f800ad3a446c6726e
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If you are enjoying the podcast please leave a review on your preferred podcast app! -
Alyssa and Jame are joined by Tihana Bicanic, to discuss the second great antifungal drug class, Echinocandins.
Part 1 of 2! (this episode we discuss the old stuff, next episode we discuss Rezafungin in more detail).
Show note for this episode found here: https://idiots.notion.site/132-133-Echinocandins-2d76a1ea09d8811f800ad3a446c6726e
(Note if you have any echo on the audio for this episode, try re-downloading the episode)
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Prep notes for completed episodes can be found here (Not all episodes have prep notes).
If you are enjoying the podcast please leave a review on your preferred podcast app! -
BIOCIDES ARE COMING FOR YOU.
Find out what they are, what the benefits and harms they have, and what we can do to control their use in consumer products.
This was a fascinating, wide-ranging discussion on the use of agents that can affect the human/animal microbiome and environmental microbes, and the problems with trying to regulate them (in the UK at least). Hope you enjoy it.
Bios:
Natalie Bennett has been a Green Party representative in the UK House of Lords for six years, after being leader of the England & Wales Party from 2012-2016. Her first degree - from the University of Sydney - was in agricultural science, and she can get very geeky about soils; she got tardigrades into Hansard (the parliamentary record) for the first time ever in her maiden speech. Her Consumer Products (Control of Biocides) Bill was introduced to the House in January 2025. Her first book is Change Everything: How We Can Rethink, Repair and Rebuild Society, and her second (Green Thinking Unlearning Outdated Ideas in Science, Economics and Politics) will be out from Routledge next April.
Anastasia “Tash” Theodosiou is an Academic Clinical Lecturer at the University of Glasgow and a Specialty Registrar in Microbiology & Infectious Diseases. Her research explores how the microbiome shapes health and disease, with a particular focus on early life; her PhD produced the world’s first human challenge study performed in pregnancy. She also coined the term microbiotoxicity, a framework for recognising the unintended impacts of antimicrobial products on the microbiome, and is a passionate advocate for embedding microbiome stewardship into clinical practice, prescribing, and policy.
Jame is a podcaster. He works for the NHS on occasion.
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Prep notes for completed episodes can be found here (Not all episodes have prep notes).
If you are enjoying the podcast please leave a review on your preferred podcast app! -
Flustered by fluconazole?
An ignoramus on itraconazole and isavuconazole?
Puzzled by Posa? VEXED BY VORI?
Never fear: You can be amazed at the Azoles, just learn how to use 'em right! That's what this episode's all about! Alyssa and Jame UNITE in the first of our episodes on antifungal drugs!
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Prep notes for completed episodes can be found here (Not all episodes have prep notes).
If you are enjoying the podcast please leave a review on your preferred podcast app! -
AKA Penicillin Allergy 3: Delabel Hard With A Vengeance
A departure from our semi-annual penicillin allergy episode: one on cephalosporin allergy!
Jame and Callum are joined by Fionnuala Cox to discuss Cephalosporin allergy in general, and the CEPH-FAST risk assessment tool in particular.
Ever wanted to know how to deal with cephalosporin allergy? Listen on!
Paper here:
Cox F, Vogrin S, Sullivan RP, Stone C, Koo G, Phillips E, et al. Development and validation of a cephalosporin allergy clinical decision rule. Journal of Infection. 2025 June 1;90(6). Available from: https://www.journalofinfection.com/article/S0163-4453(25)00089-1/fulltext
https://doi.org/10.1016/j.jinf.2025.106495
(It's open access, don't worry)
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Yo ho ho, for our listeners dearest
We present an antibiotics tier list
Ranking drugs from S to D
In a manner oh so Christmassy
So sit back relax and have a drink
As we discourse in cladist think
And if you rank a different way
We'll forgive you this Christmas day.
Proper episodes next year. See you in 2026!
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If you are enjoying the podcast please leave a review on your preferred podcast app! -
In which Callum and Jame discuss Brucellosis, named after a Scottish feminist, a disease hard to diagnose but easy to treat, as long as the treatment works which it may not. Listen on!
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If you are enjoying the podcast please leave a review on your preferred podcast app! -
It's the best pun Cal's ever done, and I don't say that lightly, son. Here's an episode on Capnocytophagia!
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If you are enjoying the podcast please leave a review on your preferred podcast app! -
It’s World Antimicrobial Awareness Week! And did you know AMR might kill us all? The British Society of Antimicrobial Chemotherapy do, and they’ve partnered up with interested politicians to drive AMR up the political agenda. But how?
Jame is joined by Dr Helen Callaby, Dr Nick Brown and Dr Danny Chambers MP to discuss the workings of the UK’s All Party Parliamentary Group on AMR, the BSAC parliamentary internship, how to get involved in pushing AMR up the political agenda, and more!
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If you are enjoying the podcast please leave a review on your preferred podcast app! -
SporotrichosisMycetomaChromoblastomycosis...Entomophthorales.
Let's face it: you don't know anything about these diseases.
That's OK: neither do Callum or Alyssa. That's why we've got a guest! Dr David Chandler is a Consultant Dermatologist, BSMM member and is a member of the Global Mycetoma Working Group. Listen on for everything you need to know about chronic subcutaneous infections caused by moulds!
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Alyssa and Callum talk all things dermatophytes and Tinea:
Tinea capitis – scalp, hairTinea corporis – trunk, limbs (ringworm)Tinea manuum/pedis - palms and soles (athlete’s foot)Tinea cruris - groin (jock itch)Tinea barbae - beard area and neckTinea faciale - faceTinea unguium / onychomycosis - nailsWhat does Anthropophilic mean and how do you pronounce it? Tune in to find out.
Show notes for this episode here: https://idiots.notion.site/12-Moulds-Dermatophytes-3e6b963f48db46808f67985884be5794?source=copy_link
Support the show
Support us on:
Patreon: https://www.patreon.com/cw/IDIOTS_pod
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Prep notes for completed episodes can be found here (Not all episodes have prep notes).
If you are enjoying the podcast please leave a review on your preferred podcast app! - Vis mere
