Episodes

  • OK SO - -

    I help people solve their health puzzles, and they are often complex puzzles. I love it, but it can be a little confusing to explain what I do, especially if you are just getting into the "chronic health problems" world.....but my expertise is in connecting the dots on symptoms, mechanisms, physical diagnosis and lab interpretation and using those clues to help people solve puzzles.

    So we start with a very detailed health history (90 mins), then this guides us towards certain lab testing, then based on the history, symptoms, and lab testing I give recommendations consisting of diet, lifestyle, and supplement protocols. This is similar to many health practitioners, but what SETS ME APART is my clinical experience, knowledge, and ability to explain these mechanisms to people so they make sense, give them goals, keep them on track, and put their puzzle pieces in the right order. Hopefully if you have heard the podcast you have realized that they way I put puzzle pieces together is different than most, so we are able to solve puzzles that most can't solve. At least that's always my goal :)

    Krystal was referred to my office, and initially she had A LOT OF SYMPTOMS - regular headaches, light sensitivity, vertigo, chemical sensitivities, hormone imbalances, she was taking 4 naps a day, she had a history of prednisone and other medication usage, she had to use her rescue inhaler all the time, she was sensitive to fragrances, foods, had gut inflammation with a severely restricted diet, you name it. I told her when she came in that she was one of my top 3 most sensitive patients, and that's a hard prize to win!! So then we ran labs, we took lots of supplements, we did parasite cleanses, coffee enemas, detox support, etc etc....and now she is doing great....

    That's the long story short. The details are in the podcast, but we talk about the MINDSET required for healing, we talk about her journey, we talk about how we EXPECTED roadblocks and setbacks, but we figured them out and we worked through them.

    This is a great podcast, but my favorite part is hearing Krystal's mindset and the way she thought about healing. My recommendations and protocols are NOT what separates who gets well and who doesn't get well, mindset does. This is YOUR health journey, not mine. It's YOUR responsibility. Krystal is a Life Coach, and we talk extensively about how her skills in that area helped her have the healing mindset necessary to get good results, and how she has helped other people change the way they THINK about their symptoms, illness, or healing journey.

    If you are in need a great life coach, look her up!!

    @krystal.stegmaier on Instagram
    Kystal Stegmaier - Life Coach on Facebook
    and her website:
    krystalstegmaierlifecoach.com

    If you are interested in working with me, you can schedule a New Client Consultation with me here, or check out my Instagram, Youtube, check out our website www.autoimmunedocpodcast.com or listen to more podcast episodes to learn more about my approach to complex illnesses.

  • Autoimmune Doc Supplement Store

    Limbic System and Cell Danger Response Video

    Binaural Beats Video

    Here is the final episode in my 4-part series on the brain - Brain Solutions. This episode ties together the previous 3 episodes: you have to understand some of the general targets you are aiming at - neuroinflammation, methylation, oxygenation, low omega 3s - that is episode one, Brain Overview. Next you have to understand the neurotransmitters - dopamine, serotonin, GABA, acetylcholine - this is episode two. Last, you have to understand the brain regions - the prefrontal cortex, amygdala, hypothalamus, cerebellum - this is episode three, Brain Regions.

    NOW, you can choose your tools from the solutions tool box, and that is what this episode is all about.

    In this episode I focus on the tools that I personally use, which are typically inexpensive and non-invasive, but I also give my opinion on several other options that are out there available for people who can access them, such as hyperbaric oxygen therapy and neurofeedback. Many of these solutions are the specific supplements that I suggest to support neuroinflammation or neurotransmitters, when I might recommend using them, and how I would use them, but I also discuss other tools for vagus nerve stimulation, vestibular rehabilitation, and more. There are a lot of options out there and a lot of opinions, I hope this helps you choose the right tools for you. Purchase TENS Devices, supplements, and more at our online supplement store!

    Schedule a New Client Consultation with me HERE.

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  • Here is episode #3 in my series on brain health.....let's recap.

    The brain is complex. There are important mechanisms (neuroinflammation), functions (neuronal signaling), neurotransmitters (serotonin, dopamine, GABA), and regions that are helpful to understand for those out there trying to support their brain or support a certain symptom such as brain fog or heightened anxiety.

    The first episode was about general brain health, the second was about neurotransmitters and their functions, and this episode is about specific brain regions, including the prefrontal cortex, the hippocampus, the amygdala, and the cerebellum.

    For example, the amygdala is part of the brain's Limbic System. The amygdala is the "fear center" and increased amygdala activity is associated with heightened anxiety....but the neurotransmitters involved may be epinephrine and GABA, and the mechanism may be microglial neuroinflammation, which may be triggered by mast cell activation, and the underlying cause(s) could be gut inflammation, it could be a traumatic childhood, or it could be mold toxins, or gluten, or it could be a combination, and it's always a combination of factors that need to be addressed.

    Understanding these brain regions and their functions can give you options (that aren't just supplements...) for training or rehabilitating a specific area, such as specific exercises you can easily do at home, or avoiding gluten and dairy to avoid cerebellar cross-reactivity.

    My next episode will tie all of these brain puzzle pieces together. It's all about brain solutions (which I give a lot of in this episode as well...), including all the supplements, brain exercise programs, and dietary strategies that I employ when trying to help someone support their brain health and function, and all of the options available and when or why you might consider using them.

    Enjoy! Leave a rating and review, and share this with a friend or family member with a brain!

  • One of the most important things a healthy brain needs is appropriate neurotransmitter activity. Neurotransmitters regulate our brain function, our energy, our focus, our mood, and our lives. Imbalances in neurotransmitters can come from many things, including past trauma, unhealthy relationships, bad habits, chronic stress, poor gut health, crappy diet, toxins, autoimmunity, neuroinflammation....the list goes on and on, but it can be helpful to know which neurotranmitters are imbalanced in the hopes of supporting your specific brain functions and symptoms. The most important neurotransmitters, which I discuss in this podcast, are:

    Serotonin - regulates some aspects of mood, appetite, happiness, enjoyment of activities, appreciation of art.
    Acetylcholine - regulates working memory, computation, muscle contractions, and parasympathetic nervous system (vagus nerve) activity to the gut.
    Dopamine - important for motivation, pleasure, focus, mood, addiction, thrill-seeking.
    Epinephrine/Norepinephrine - aka "adrenaline", stimulates "fight or flight" stress response centrally in the brain and also peripherally from the adrenal glands.
    GABA - the primary "calming" neurotransmitter, GABA is inhibitory and is often inadequate in symptoms of anxiety, depression, and neuroexcitation.

    These neurotransmitters can all be modulated with lifestyle strategies and targeted nutraceuticals, whether it be providing the building blocks for the neurotransmitters itself (tyrosine for dopamine for example), or impacting the receptor sensitivity (L-theanine for GABA), or using nutrients to support certain pathways like the Kynurenine Pathway, Dopamine Beta Hydroxylase, or other genetic pathways (COMT, MTHFR, MAO) of neurotransmitter metabolism. Supporting neurotransmitter metabolism can be a game changer when supporting brain function, and my goal is to teach people how to solve their own puzzles, so I hope this is helpful, next episode is part 3/4, brain regions!

  • Anxiety, Mast Cell Activation, and LPS (video)

    Cell Danger Response and Limbic System Dysfunction (video)

    Anxiety, Neuroinflammation, and Autoimmunity (podcast)

    Your brain is the most complex organ in an incredibly complex body, and it's running the show. I continue to see a massive uptick in brain-based symptoms coming into my clinic (and everyone else's), such as depression, anxiety, depersonalization, derealization, dizziness, vertigo, fatigue, brain fog, memory loss, panic attacks, bipolar episodes, nausea, pain syndromes, and so much more.

    I have a lot of brain-related content available, and I linked some at the top of the show notes for this episode. My goal with this series is to help people understand how all these puzzle pieces fit together - neurotransmitters, brain regions, how to use all of the different tools available. Today's episode is an overview of some of the more important concepts in the brain, and reviewing what a healthy brain needs:

    Neurotransmitter Activity - serotonin, dopamine, acetylcholine, epinephrine/norepinephrine, GABAAdequate Oxygen - good blood flow, no anemiaSteady Fuel - no hypoglycemia, and no insulin resistanceProper Lipid Morphology - omega 3s, DHA, phosphatidylcholineHealthy Stimulation - learning, fun, skills, memory, coordination, visual complexity, connecting with other humansHormone Balance - estrogen, testosterone, progesterone, cortisol (steroid hormones), thyroid Gut-Brain Connection - good micro biome, bacterial diversity and abundance, no infections/overgrowths, good vagus nerve activityHealthy Circadian Rhythms - good light exposure, good sleep....

    I also briefly talk through a patient's case history and some of her symptoms, lab findings, and how we have kept her brain healthy and kept her symptoms under control over the past several years. The next several episodes will be more of this, teaching you how to solve your own puzzle!

  • Long Haulers UPDATED (video)

    Long Haulers Mechanisms (video)

    SARS-CoV-2 and the gut-brain-lung axis (video review of a research paper)

    From the onset of the pandemic through the last (almost) 3 years, we have continued to find out new things about how people respond after coronavirus infection. Not surprisingly, there is more and more research coming out indicating that an increased autoimmune response may be responsible for many of the lingering symptoms.

    Early on in the pandemic, SARS-CoV-2 was nicknamed "The Autoimmune Virus" because it appeared to be triggering more of an autoimmune response than other viral infections. As science has continued to evolve our understanding, it turns out that COVID infection is absolutely associated with increased autoimmunity - both exacerbation of existing autoimmunity as well as new autoimmunity.

    Autoimmunity is the process in which the body "loses self tolerance" for tissues of the body and begins to initiate an immune "attack" against self-tissue (thyroid, joints, brain, gut, etc) as if they were a foreign invader - which leads to chronic inflammation, tissue damage, and a gradual loss of function, and can eventually become a diagnosed autoimmune "disease" like Type 1 Diabetes or Rheumatoid Arthritis.

    One of the ways that viruses can trigger autoimmunity is by means of "molecular mimicry", or what can be described as a case of "mistaken identity". In this podcast I describe it like this - I have a blue F150 pickup truck, extended cab, long bed. There are many blue F150s on the road, so what if the police were looking for a blue F150 and they accidentally pull ME over instead of the bad guy they are looking for? That's a case of mistaken identity. Well COVID antibodies can also misdirect their immune attack, and they can accidentally attack many tissues, and in this episode I go through dozens of different autoantibodies that have now been associated with COVID - - thyroid autoantibodies, neurological autoantibodies, mitochondrial autoantibodies, and more.

    We now know that COVID infection can lead to a myriad of symptoms, and they can all be described as the "long-haul", but the mechanisms can be all quite different, so they are NOT all the same thing, and it's not fair to group everyone together as "long-haulers". You could have POTS, dysautonomia, clotting/coagulation, neurological (depression, brain fog, and TONS of anxiety...), digestive changes, fatigue, or you could develop post-COVID diabetes or arthritis.....as science continues to learn more are we going to find that it's ALL autoimmune in nature?? Only time will tell, but I believe that treating any condition as if it were an autoimmune case is never a bad approach - decrease inflammation, balance the immune system, and look for (and remove) any root cause triggers!

  • Your liver is seriously pretty amazing. I'm a 'mechanisms' kind of guy, and the liver is the king of mechanisms, including:

    - The liver is crucial for metabolism, regulating blood sugar, lipid, and protein metabolism.
    - The liver participates in immune surveillance and pathogen clearance, and is intimately connected with the gut.
    - The liver performs "hepatic biotransformation", or transforming toxins into things that can be excreted, aka DETOXIFICATION.

    The liver can be damaged by many things including lifestyle, alcohol, viruses, parasites, and especially toxins. As liver damage progresses, the liver becomes more congested, toxins begin to accumulate, and metabolic dysfunction can follow. Liver damage is generally a spectrum of worsening fibrosis, and often starts with "fatty liver" and then progresses toward cirrhosis, which is liver scarring. Liver damage can be detected by several labs, and I discuss these labs in detail.

    In the liver there are many functions, but this podcast focuses mostly on hepatic biotransformation, or detoxification. This includes Phase 1 and Phase 2 of liver detox, cytochrome P450, and includes processes like methylation, sulfation, conjugation, and more. These processes require many cofactors such as B vitamins and amino acids, and I discuss these all in detail.

    There are also many genetic mutations that can affect liver and detoxification, so I discuss these as well, along with the common and popular liver supplements and what their mechanisms are. All together this is a comprehensive overview of everything I know about the liver and how I use that information clinically in helping sick people get well!

    Youtube video about Liver, Carnitine, and Depression....

  • Parasites are interesting. That word means different things to different people, some people are terrified of the idea of worms living inside their body, but at the same time parasite cleanses are super trendy on Instagram and social media, and yet some people think that parasite cleansing is the solution to all health problems....which one is it?

    Parasites are paradoxical in the research world, many areas of the world that have endemic parasitic infections have virtually no autoimmunity, and helminth therapy is actually an incredibly promising treatment for certain autoimmune cases. The reason that parasites are so relevant in the population of people that I see is because of our junk food supply, the toxins everywhere, and the rampant metabolic and immune disruption - - but they aren't always the ONLY culprit, they show up more often with the presence of heavy metals, Candida, SIBO, mold and other toxins. When they are recognized as bad, they elicit a strong and specific immune response that I talk about in detail in the podcast, triggering a Th2 immune response via IL-4 and activating mast cells and histamine, and often keeping someone stuck there (sound familiar??) as they become allergic to more foods, chemicals, and more sensitive to their world. They can also drive inflammatory bowel processes, cause liver and gallbladder issues, disrupt neurotransmitters, infect the brain, and much more.

    While I certainly do NOT believe that parasites are a piece of every person's health puzzle, I do think "parasite cleansing" can be incredibly helpful in the right situation. In this podcast I share my personal opinions and personal experiences that I have had with parasites (including when I passed one!) and many stories of helping people with them, and they are pretty drastic stories. I also talk about the testing available and what I personally look for, as well as the supplements and protocols I recommend for people and how those are given, and basically everything that I know and think about parasites!

    Leave a rating, review, share this episode with a friend!!




  • Ok so let's talk about gut health. Gut health and detox are pretty much the two most important topics, and toxins affect gut health....but good gut health is necessary for proper detoxification.....I think gut health wins. At least for this next podcast series :)

    Gut health is foundational to health, inflammation, and aging. It's so crucial, but so few people seem to have it mastered IF they are still experiencing symptoms, and I mean ANY symptoms - joint pain, fatigue, anxiety, depression, bipolar, metabolic, certainly autoimmune flares, not just digestive symptoms. I'm going to go deeper into some specific topics in the next few episodes, but this one is an overview, and I made a list of the 10 most important things for gut health. The first 3 are symptoms, the next 4 are mechanisms, and the last 3 are infections, and understanding these 10 things will give you a pretty good grasp on understanding gut health and digestion overall!

    Diarrhea - I talk about IBS, IBD, low microbiome and good bacteria/probiotics, glutamine, mast cells, and hydrogen SIBO....Constipation - I talk dysbiosis/methane, and a LOT about vagal motor outflow and vagus nerve activity that controls motility as well as HCL, bile, enzymes....Bloating - When I hear bloating I think small intestine and fermentation. Dysbiosis is often at the root, which includes proper digestion (HCL and bile), and I touch on SIBO/SIFO, avoiding FODMAPs foods....Digestion - This is critical!! Chewing your food, being in parasympathetic mode, then proper stomach acid - it can be too high (mast cells) or too low (more common), pancreatic digestive enzymes, bile from the gallbladder (steatocrit), and of course VAGUS BABY!Dysbiosis - The 10 lbs of bacteria in your gut can become imbalanced. Low good bacteria, general microbiome imbalances…..and LPS!!!!!Leaky Gut - Everyone can have some intestinal permeability, is yours pathological, and if so what kind is it - paracellular or transcellular? Food Sensitivities - IgG testing, and how food sensitivities can drive autoimmune reactivity, general inflammatory tone, and initiate T cell mediated tissue damageSIBO - Bloating! Fermentation of fibers, starches, sugars, FODMAPs ...why you need HCL, bile, vagus outflow……Why I think SIBO testing is dumb….Candida - OMG….the single biggest thing I see. Antibiotics, sugar, stress, birth control, mold exposure, can drive a Th17 inflammatory response (autoimmune), can also drive Th2 (and both will decrease Th1)......and why I love urinary organic acids testing for fungal issues.Parasites - this I am going to do a whole episode on because it’s crazy, it’s quite frankly pretty controversial in the autoimmune world, is it better to have or to not have them??? The answer is IT DEPENDS. But I do talk about someone who was diagnosed with Ulcerative Colitis and it actually seemed to be a parasitic infection, pretty interesting story :)

    Share this with someone, subscribe, leave a rating and review, and follow me elsewhere!

  • Ok so the past several episodes have been about toxins, and this is the last and perhaps most important episode - how do you avoid toxins? Well, we don't sell plastic bubbles......

    Toxins are everywhere, and detoxifying and removing them from your body is often a really important piece of healing from any inflammatory or autoimmune condition, but what if you have never experienced many symptoms or chronic disease? It's just as important!!

    In this episode I drop a ton of recommendations and suggestions (as always) for areas of your life to focus on if your goal is a non-toxic lifestyle, including:

    Clean Air - I think this is the most important/underlooked area in non-toxic living!! Indoor air quality matters more than outdoor air quality (where do you live? indoors.), but both matter. Particulate matter, dust, mold, mycotoxins, pollution, formaldehyde, VOCs, off-gassing - - I discuss all of these risks in this episode along with air purifiers, air scrubbers, special filters, formaldehyde meters, ozone, and more for CLEAN AIR!

    Clean Water - this one is pretty easy to understand and something that many people address - - filter your water! Water could have metals, medications, hormones, pesticides and other toxins toxins toxins - - and sometimes well water is worse than municipal - - and I talk about all these risks. The solution is to filter your water, but what is the best??? My answer may surprise you.....(listen to the episode!)

    Clean Food - another fairly well-understood and obvious one, but besides the problems with some "natural" foods (high sugar, vegetable oils, gluten, dairy, lectins), your food is TOXIC!!! Food has pesticides, aluminum, dyes, preservatives, and all sorts of toxins that need to be removed via your detoxification pathways. Eat organic, but I also talk about the value of knowing where your food comes from and some of the resources my family utilizes to get clean food.

    Clean Skin - I admit this is not my specialty, I don't really use anything on my skin, but the point is that the stuff is TOXIC, and these toxins accumulate and affect things like hormones and fertility. Aluminum in deodorant, sodium laurel sulfate in shampoo, parabens in lotion, coal tar in lipstick, VOCs in nail polish - - don't put anything on your skin you wouldn't eat!!

    Clean Brain - believe it or not, I'm not talking about neurotoxins in this section, I'm talking about what you put into your MIND - - is social media and video games or books and positive affirmations? Your brain can be neurotoxic with aluminum, pesticides, or mycotoxins, but a toxic MIND can sometimes be even worse.

    I also touch on a few other things - - exercise, sauna, and probably more :) As always, let me know what you think, leave a rating or review, and follow my social channels!!

  • Purchase these detoxification products HERE!

    Ok this series is a lot like the mitochondria series, it requires multiple episodes because order to understand the solutions you have to understand the mechanisms first. Last episode was all about the most important "big picture" concepts for detoxification such as understanding the old "toxic bucket" metaphor, my next episode will be about how to make sure you aren't filling the bucket....but this episode is all about how you empty the toxic bucket - aka how you DETOXIFY YOUR BODY.

    In this episode I go over MANY MANY tools that I use regularly to support detoxification, including lifestyle strategies like sauna, coffee enema, rebounding, etc and I give my opinion on various supplement companies, individual ingredients (different important vitamins, herbs, amino acids, etc), and also all the specific products that I like and use regularly, and why I like them, including support for:

    Bowel FunctionKidney FunctionLiver and Bile FlowLymph DrainageBINDERS!GlutathioneMethylationMitochondriaCell Membrane Support


    and lots, lots more. ENJOY! Please leave a rating and review, follow me on Instagram and Youtube, and share with a friend!!


  • Detox Pathways and Protocols (Youtube)

    Free 15-min phone consult!

    Website and Supplement Store

    So - yup, toxins are a big problem. We are exposed to tons of them, and if our bodies aren't detoxifying properly, they can accumulate or cause damage to our cells, organs, and systems and wreak havoc on our lives. So how do you make sure you aren't overflowing your bucket? Here are 10 Important Concepts:

    Bucket Theory explains everything - keep this in mind if things are NOT getting better. SOMETHING is still filling the bucket from somewhere if you are actively trying to detoxify and leading a non-toxic life and you aren't improving. You have to empty the bucket faster than you are filling - you either aren't emptying it well, or you are still exposed somewhere.Breathing - There are only a few "exits" for things to get out of the body, breath is one of them. Think about a roadside alcohol test - you breathe out toxins to get rid of them.Peeing - this one is more obvious that you are "getting rid of waste", but the kidneys filter toxins and toxic metabolites, and you pee them out, so that system has to be working well too. Pooping - This one is the most obvious - - waste is bad so you want to get it out of you!! Your poop is how you get rid of MANY MANY toxins, and if your gut is not moving well, everything else backs up. Sweating - You are slightly limited on how much you can speed up your breathing, peeing, and pooping, but you can always open the other exit - sweat. Many toxins have been found excreted in the sweat - mycotoxins, BPA, parabens, metals, etc, so sweating is crucial for detoxification.Liver/Bile Flow - The liver filters toxins (through many processes - phase I and II, cytochrome P450 enzymes, glutathione, conjugation, glucuronidation, methylation, etc). These toxins are then put into bile, which is stored and released by the gallbladder. You have to have good liver function to filter the toxins, and then you have to have good gallbladder function and bile flow for the toxins to get into the gut, then you have to be pooping for them to get out.Lymph Drainage - The lymphatic system is one way that toxins and waste products are transported around the body to be excreted, and your lymphatic system has to be moving, it can't be stagnant. Cell Membranes - Toxins damage your cell membranes (including mitochondrial membrane), causing lipid peroxidation, stiffening, and poor membrane fluidity. Then toxins can also STORE in the cell membranes, so you need good healthy cell membrane support - this can be really important for detoxification.Mitochondria - THEY DO IT ALL!!!! Toxins store in the mitochondria, they damage the mitochondria, they affect fatty acid beta oxidation, Kreb's Cycle, Oxidative Phosphorylation, all the things - and mitochondria power detoxification in the liver, organs, cells, etc. It's all mitochondrial!Relevant Genes - There are a lot of relevant genes in detoxification, and it's super important. Many of them relate to "methylation", like MTHFR, COMT, PEMT, HNMT, but there are many others that regulate processes like glutathione recycling, cytochrome P450 activity, and many many more.
  • www.autoimmunedocpodcast.com

    The thyroid is a REALLY, REALLY important gland.

    Thyroid hormones regulate your metabolic rate and because of that, are important for basically every function in your body to work properly - all of your energy, healing, digestion, brain function, cellular functions, all of it. Every single cell in your body has receptors for thyroid hormones. It's also the target of the single most prevalent autoimmune disease in the U.S. - Hashimoto's thyroiditis, and millions of Americans have diagnosed thyroid conditions, while potentially 100s of millions have subclinical thyroid "problems".

    The thyroid is very susceptible to damage from toxins, so in this podcast I talk about those toxins, what they are, where they come from, and why you should be scared of them. The toxins are, in no particular order:

    - BPA - found in plastics, receipts, etc
    - Mercury - found in fish, dental fillings, some vaccines
    - Perchlorate - mostly found in fertilizers and drinking water
    - Fluoride - mostly found in drinking water and dentist's offices

    Toxins cause problems. Sometimes they bind to tissue and cause adducts and autoimmunity. Sometimes they block receptors, sometimes they just deplete glutathione and drive oxidative damage causing cellular inflammation. But no matter their mechanism, they can wreak havoc on your health (hence the obvious name....they are TOXIC, duh!), and it's very important to know about them and how to avoid them - if you want to avoid problems like thyroid problems!!

    Youtube Video about BPA and Autoimmunity!

    Listen back to the last episode (TOXINS TOXINS TOXINS!) and my previous episode on Toxins and Autoimmunity (episode 25), and my previous episodes on the Thyroid Puzzle - episodes 14, 15, and 16!

  • www.autoimmunedocpodcast.com

    OMG where do I begin with toxins?!?

    This episode is just me talking about toxins and the problems associated with chronic toxin exposure. I share some opinions, I share some stories, I share some science, but the bottom line is that toxins are making us sicker quicker, and it's a TOTAL EXPOSURE thing, not simply this toxin or that toxin. It's your TOXIC BUCKET, and it fills drop by drop.

    In this episode I give a shout out to Dr. Jill Carnahan MD and her personal story with toxins (cancer, Crohn's, Mold...), I talk about toxins from fertilizers, golf courses, drinking water, hair and nail salons, glass work, even just my office tested high for formaldehyde from the carpet. I also talk a little bit about carnitine, the liver, genetics, and some of my interesting patients - mothers and sons, daughters, sisters, the similarity in their testing results and the genetics that they likely share, along with the environment.

    I don't think I talked about glutathione in this episode at all?!?! Don't worry, I will soon :)

    This podcast is just me talking about toxins and toxicity and not as much of a "lecture", but I think it's interesting and valuable content and I hope you do too. I also often think that if you heard some of the stories that I hear day in and day out, you would take toxins pretty seriously too!

  • How to Stimulate Your Vagus Nerve with a TENS Device

    UPDATED Vagus Nerve Stimulation Video with new Ear Clips

    Research Studies on Vagus Nerve and Brain (video)

    Vagus Nerve Stimulation "has been life-changing!" (video)

    BUY a TENS and EAR CLIPS: www.autoimmunedocpodcast.com

    The Vagus Nerve is the primary nerve of the parasympathetic nervous system, and it has gained wild popularity lately in the scientific and biohacking, alternative wellness, and autoimmune disease communities.

    As the primary nerve of the PNS, the vagus is largely responsible for "pushing the brakes" on the stress response, the sympathetic nervous system.

    The vagus innervates the heart, lungs, liver, spleen, gallbladder, diaphragm, entire digestive tract, and more. It's two way nerve 'superhighway system' acts as the modulator of the "gut-brain connection", sending sensory signals upward from all of your organs and sending signals downward regulating stomach acid, enzyme, and bile release, digestive motility, and more, and back up to your brain. Decreased vagal tone is associated with both inflammatory digestive diseases as well as psychiatric diseases like depression and PTSD.

    The vagus also sends nerves to the spleen, and its activation blocks the release of Tumor Necrosis Factor Alpha (TNFa), and in the liver blocks Interleukin 6 release from Kuppfer cells, all through something called the Cholinergic Anti-Inflammatory pathway.

    The only place on the outside of the body that the vagus nerve travels is part of the ear, oddly enough, but the vagus nerve can be stimulated by acupressure or my preferred method which I talk about in the podcast - using an inexpensive TENS Device with an ear clip.

    The vagus nerve can also be stimulated by yoga, mediation, acupuncture, chiropractic, deep breathing, contrast showers, humming, gargling, and gagging, and I speak on all of these things in this episode!

  • www.autoimmunedocpodcast.com

    Anxiety was escalating at a rapid rate before 2020, and now it's just crazy. Long-haulers, mandates, lockdowns, wars, masks, headlines, our kids.....let's just say it isn't expected to get any better anytime soon, hence counseling services are increasing, doctors visits and prescriptions are increasing, but so are people searching for information and trying to solve their anxiety puzzle without medications, on their own. There are tons of options for medications, supplements, and general advice out there - where do you turn and what do you do?? Understand the mechanisms of anxiety, neuroinflammation, and autoimmunity.

    UNDERSTANDING MECHANISMS PROVIDE SOLUTIONS!

    I have at least 20 things in my Vitamin Store that I have used in my clinic that have helped people tremendously with anxiety, including magnesium, CBD, L-theanine, B6 and other B vitamins, keto diet, avoiding gluten or dairy, binders, methyl donors, sauna, herbs for pathogens, probiotics, adaptogens, vagus nerve stimulation. Some of these people were mold, Lyme, EBV, IBS, or autoimmune disease patients with a list of 10+ other symptoms, but some were kids, moms, dads, people who just dealt with a lot of anxiety but otherwise had few complaints. It can happen to anybody. What are the mechanisms for YOU?? Here is a list of 10 things you need to know about when searching for the next clue to solve your health puzzle:

    1. Mitochondria - the batteries behind it all!! Also the cause behind it all.....listen to episodes 30, 31, 32 for more info on mitochondria but you have a QUADRILLION of them in your brain, so they are kinda important.....

    2. Brain Cells - Neurons vs. Microglia vs. Mast Cells vs. Astrocytes.....you don't need to know everything, but a little bit about each one can help!

    3. Brain Regions - limbic regions - amygdala, insula, hippocampus, hypothalamus; cerebellar-vestibular regions

    4. Neurotransmitters - GABA/Glutamate, Serotonin, Dopamine, Acetycholine, Epinephrine, Norepipheprine

    5. Hormones - HPA Axis (adrenals), Thyroid, Androgens, Estrogens, and most importantly Cortisol

    6. Blood-Brain-Barrier - protector of the brain - damaged by head traumas, glutathione depletion, histamine, gut inflammation and permeability (leaky gut)

    7. Dysfunctional Pathways - Reactive Oxygen/Nitrogen Species (ROS/RNS), LPS, Mast Cell Activation, Kynurenine Pathway, Methylation, NO/ONOO, iNOS, excitotoxins (MSG, red 40), EMF radiation

    8. Nervous System Balance - Sympathetic/Parasympathetic balance - "fight or flight" vs. "rest and digest"

    9. Mitophagy/Autophagy - the clearing of "junk" from the brain

    10. Autoimmunity! - Self-tissue antibodies against things like GAD-65, cerebellum, thyroid, Myelin Basic Protein, Synapsin, Asiologanglioside, etc


    These are 10 heavy topics!! But they are all important. You don't need to know everything about them, but knowing a little bit about each topic can help you figure out a bit more what's going on in your brain!

  • Long Hauler Webinar

    How To Stimulate Your Vagus Nerve with a TENS Device

    Long Haul, long COVID, Post Acute COVID Syndrome (PACS)....call it what you will - the bottom line is that a lot of people are experiencing new, lingering symptoms such as:

    FatigueBrain FogAnxiety/DepressionInsomniaHeadachesHair LossHeart PalpitationsMenstrual Changesand more!

    People are suffering with these new symptoms and don't know where to turn, there is a lot of opinion on the internet but WHAT IS REALLY GOING ON???

    That's the point of this podcast (and the Long Haulers Youtube webinar linked above!) - explain (some of) the mechanisms, explain why you may have gotten here, how you can know what YOU need to target, go over the labs that can help explain your personal symptoms, talk about the supplements that work, and the natural lifestyle strategies that make sense, and review the science and research behind all of it.

    Please share this!! A lot of people are experiencing these symptoms and don't know where to look for answers!!

  • This episode is the 3rd in our series on mitochondria, and they've all been leading up to this - - what can you do for your mitochondria?

    The good news is there is a lot you can do to support the different mitochondrial and metabolic processes, so that's what this whole episode is about. I discuss a wide variety of important strategies, some well-known and some becoming more popular, and I go over the mitochondrial mechanisms behind them, including:

    Exercise - nothing is better for your mitochondria!Targeted Supplements (including my Top 10 List!)Fasting - Intermittent and ExtendedKetogenic Diet - a "Mitochondrial Therapy"Red/Infrared Photobiomodulation (Low-Level Light Therapy, LLLT)Cold ThermogenesisGrounding/Earthing...and why you need to avoid things like EMF radiation, excessive blue light, toxins like pesticides, mycotoxins, heavy metals, and a high sugar diet.


    Many of these wellness strategies are well-known (like exercise or avoiding sugar) while others have become downright trendy in recent years (like fasting, keto diets, cold plunges, and red light therapy), but it's because people are experiencing great results by doing these things, there is excellent science coming out about the mechanisms, and because IT'S ALL ABOUT THE MITOCHONDRIA.

  • If you missed the last episode, go back and listen to it, but the takeaway was that your MITOCHONDRIA ARE REALLY, REALLY, IMPORTANT for autoimmunity, or anything else. Like - the most important thing for your health. These little cellular batteries power your brain, your heart, your muscles, everything. When they become dysfunctional, it leads to symptoms like fatigue, weight gain/inability to lose weight, brain fog, malaise, and eventually disease processes like autoimmunity, dementia, and metabolic diseases like heart disease and diabetes.

    HOW DO MITOCHONDRIA MALFUNCTION?

    To understand how mitochondria MALfunction, you have to understand some basics about how they are SUPPOSED TO FUNCTION PROPERLY (and how to test that!) so that you can support your mitochondria appropriately with strategies I will discuss in the next episode.

    In this podcast I describe 4 main aspects of mitochondrial function that you need to understand in order to understand your personal metabolism:

    1. Glycolysis - this is a sugar-fermenting pathway that actually occurs outside the mitochondria, but dysfunctional cells can get "stuck" in glycolysis, which ferments sugar to produce energy less efficiently than "respiration". YOU DON'T WANT THAT!

    Viruses induce a glycolytic shift, it helps them survive. Toxins induce a glycolytic shift. But most of all, a high sugar diet and a sedentary lifestyle will encourage your cells to get "stuck" in this glycolytic shift, which is a hallmark of many cancer and Alzheimer's cells.

    2. Kreb's Cycle and Oxidative Phosphorylation - sounds fancy, don't get PTSD from high school bio, but this is the BIG MOTOR that we want our cells to use, and glycolysis is the TROLLING MOTOR (listen to episode 30 if that doesn't make sense!). We WANT the body to use the Kreb's Cycle and then the Electron Transport Chain to produce ATP (energy) because it produces the most energy with the least exhaust!

    3. Electron Transport Chain - your food gets broken down and goes through the Kreb's Cycle and those electrons get put into something called the Electron Transport Chain (ETC), which is a "chain" of 5 proteins that pass electrons from one to the other, this drives the pumping of protons and like quantum cellular magic, out spits ATP, or ENERGY. YOU WANT THAT!!!

    Poisons like cyanide and carbon monoxide shut this down immediately and you die. Popular supplements like CoQ10 help this. You want electrons passing through this chain at the highest rate possible!

    4. Beta-Oxidation - this process shuttles fat into the mitochondria to be burned for fuel, and many people have broken or "less-than-optimal" beta-oxidation function (think: "I can't burn this last 20 lbs even though I'm exercising!")

    If you have metabolic issues, it's really important to know what's wrong with YOUR mitochondria - you could have issues in #1, #2, #3, #4, or in ALL FOUR!!

    Many basic lab tests actually give you an idea of your mitochondrial function (iron, thyroid, blood sugar, inflammation....almost all labs because mitochondria power all functions). These labs are obviously very important for any case or condition, but my favorite testing for mitochondrial function is Urinary Organic Acids testing that actually shows specific markers for Glycolysis, markers of Kreb's Cycle dysfunction, Beta-Oxidation dysfunction, and much more, and gives us more detailed answers on how the mitochondria are malfunctioning so that we can support them properly!

  • It's impossible to overstate the importance of your mitochondria, whether for managing autoimmunity, avoiding chronic degenerative disease, aging gracefully, or just functioning at your highest level everyday.

    Mitochondria turn your food into energy in the same way that your motor turns your gasoline into energy. This cellular energy powers everything you do - not just getting out of bed in the morning, but thinking, healing, detoxifying, and forming memories and pathways in your brain.

    Simply put, if the motor doesn't work, nothing works. When your mitochondria don't function properly, your body will not function properly, and disease will ensue.

    Dysfunctional mitochondria are associated with autoimmunity, Alzheimer's, cancer, diabetes, heart disease, chronic fatigue, fibromyalgia, autism, and just general fatigue, pain, inflammation, brain fog, and nearly every other disease or symptom under the sun.

    Excessive sugar, chemical additives, inflammatory fats, environmental toxins, artificial blue light, electromagnetic radiation, and a sedentary lifestyle can all damage mitochondria.

    Many supplements like B vitamins, magnesium, CoQ10, and antioxidants help support or protect the mitochondria. The benefits of red light therapy (low-level laser therapy, or LLLT) come from effects on the mitochondria. Cold thermogenesis works on the mitochondria. Ketogenic diets work on the mitochondria and are often considered more of a "mitochondrial therapy" than a "diet". Sunlight helps the mitochondria function properly. Exercise is the best thing for the mitochondria!

    None of these things are that shocking, these are the lifestyle factors that make people sick and the healing strategies that can help people regain their health - but the mitochondria is the HOW.

    In this episode, I discuss this in more detail, and I give an overview of the importance of mitochondria, from a 30,000 ft view of how they function and can become dysfunctional. In the next several episodes I'm going to dive deeper into the specific functions of the mitochondria (glycolysis, Krebs cycle, beta-oxidation, electron transport chain), expected symptoms or testing for each of these specific functions, how you can support these specific functions, and how it all works. When you begin to understand these mechanisms, your solutions for health become obvious!