Episódios
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In this episode of TransplantRPh, April discusses the latest updates in endocrinology and diabetes mellitus, including advancements in treatments for primary aldosteronism, diabetic retinopathy, chronic kidney disease, diabetic macular edema, polycystic ovary syndrome, obesity, osteoporosis, Cushing disease, thyroid storm, and Graves' hyperthyroidism. Connect with April on LinkedIn at April Oliveros, YouTube at Pharmacist April, Instagram at PharmacistApril, or via email at [email protected]. Don’t miss her new e-book providing a step-by-step guide for foreign pharmacy graduates on becoming pharmacists in the USA! https://stan.store/pharmacistapril
Detailed Notes:
Monitoring After Negative Confirmatory Testing for Primary Aldosteronism:Repeat testing recommended after at least two years; 20% diagnosed with primary aldosteronism over five years.
-No Reduction in Diabetic Retinopathy Incidence with Omega-3 Fatty Acid Supplementation:Omega-3 supplementation does not provide additional benefits for retinopathy prevention.
- Subcutaneous Semaglutide and Risk of Kidney Disease Progression:** Significantly reduces major kidney events in patients with type 2 diabetes and CKD.
- Extended-Interval Intravitreal Aflibercept Dosing: Higher doses at extended intervals effective for diabetic macular edema.
- Continuous Glucose Monitoring: Modestly reduces A1C levels and helps identify glycemic patterns for behavior and pharmacologic therapy adjustments.
- Noninsulin Antidiabetic Medications and Pregnancy: No increased frequency of congenital anomalies, but still avoided due to lack of comprehensive safety data.
- Inositol Ineffective for PCOS: No significant improvements in metabolic or hormonal measurements.
- Risk of Suicide Attempts in PCOS: Higher rate of suicide attempts compared to controls; mental health support needed.
- Premature Ovarian Insufficiency and Impaired Sexual Function: Lower sexual function scores; systemic estrogen therapy not effective.
- Bariatric Surgery and PCOS: Increases spontaneous ovulatory events and improves cardiometabolic profiles.
- Effects of Tirzepatide Discontinuation on Weight: Partial weight regain after discontinuation; long-term treatment may be necessary.
- Severe Hypocalcemia with Denosumab Therapy: Higher incidence in dialysis patients; increased monitoring needed.
- Risk of Autoimmune Disease After Surgical Cure of Cushing Disease: Higher rate of new-onset autoimmune diseases; long-term monitoring recommended.
- Potassium Iodide for Thyroid Storm: Reduces hospital stay and costs; supports use in acute management.
- AI Decision Support for Thyroid Nodule Classification: Improves accuracy and consistency; reduces unnecessary biopsies.
- Selection of Therapy for Graves' Hyperthyroidism: Shift towards antithyroid drugs; patient preferences and radiation concerns influence treatment choice. -
In this episode of TransplantRPh, April discusses the latest updates in neurology, including advancements in treatments for cerebrovascular disease, epilepsy, headache, movement disorders, neuromuscular disease, and neurooncology. Connect with April on LinkedIn at April Oliveros, YouTube at Pharmacist April, Instagram at PharmacistApril, or via email at [email protected]. Don’t miss her new e-book providing a step-by-step guide for foreign pharmacy graduates on becoming pharmacists in the USA! https://stan.store/pharmacistapril
Detailed Notes:
Surgical Decompression for Severe Cerebral Venous Thrombosis:Hemicraniectomy shows promise in selected cases, particularly younger patients with less severe preoperative findings.
- Mechanical Thrombectomy for Extremely Large Core Infarcts: May benefit patients with ASPECTS of 0 to 2, challenging existing selection criteria.
- Reversal Strategy for Intracerebral Hemorrhage: Andexanet alfa demonstrates higher hemostasis rates but increased thrombotic events.
- Risk of Epilepsy After Aneurysmal Subarachnoid Hemorrhage: 12% of patients develop epilepsy within seven months, with several identified risk factors.
- CGRP Antagonists for Migraine Prevention: Now considered first-line therapy based on efficacy and safety.
- GLP-1 Receptor Agonists in Parkinson Disease: Mixed results in trials; larger studies needed.
- Suicidality in Parkinson Disease: 22% prevalence of suicidal ideation; importance of depression screening and treatment.
- Efgartigimod Alfa-Hyaluronidase in CIDP: Shows significant improvement and reduced clinical deterioration.
- Behavioral Therapy in ALS: ACT improves quality of life in ALS patients.
- Tovorafenib in Pediatric Low-Grade Gliomas: Shows promising response rates and duration in BRAF-altered gliomas.
- ONC201 in H3 K27M-Mutant Diffuse Midline Glioma: Promising activity with a 20% response rate and median duration of 11.2 months. -
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In this episode of TransplantRPh, April discusses the latest updates in drug therapy, including advancements in treatments for hepatitis C, intracerebral hemorrhage, food allergies, eosinophilic esophagitis, paroxysmal nocturnal hemoglobinuria, chronic lymphocytic leukemia, chronic inflammatory demyelinating polyneuropathy, and Duchenne muscular dystrophy. Connect with April on LinkedIn at April Oliveros, YouTube at Pharmacist April, Instagram at PharmacistApril, or via email at [email protected]. Don’t miss her new e-book providing a step-by-step guide for foreign pharmacy graduates on becoming pharmacists in the USA! Detailed Notes:
- Cost-Effectiveness of Treating Hepatitis C Virus Infection During Childhood: Early intervention saves nearly $50,000 in lifetime healthcare costs.
- Reversal Strategy for Intracerebral Hemorrhage:Andexanet alfa shows higher rates of hemostasis but with increased thrombotic risk.
- Omalizumab for Food Allergy: Approved for reducing allergic reactions to multiple foods, requires regular injections.
- Benralizumab for Eosinophilic Esophagitis: Achieves higher rates of histologic remission, need for more biomarkers.
- Iptacopan for Paroxysmal Nocturnal Hemoglobinuria: Reduces transfusion needs, risk of serious infections.
- CAR-T Cell Therapy for Multiply Relapsed CLL: Approved for patients after two or more lines of therapy.
- Efgartigimod Alfa-Hyaluronidase in CIDP: Shows significant improvement in symptoms and lower rates of clinical deterioration.
- Givinostat for Duchenne Muscular Dystrophy: Slows disease progression, particularly in the four-stair climb test. -
In this episode of TransplantRPh, April introduces the new 'What's New' series, covering the latest advancements in allergy and immunology. From new treatments for COPD and eosinophilic esophagitis to breakthroughs in gene editing therapy for hereditary angioedema, stay updated with the most recent findings. Connect with April via email at aprilfortinoliveros, and follow her on LinkedIn, YouTube, and Instagram. Detailed Notes:
Ensifentrine for COPD: Approved for stable COPD, improves bronchodilation, dyspnea, and reduces exacerbations.
- Dupilumab for COPD: Reduces exacerbations in patients with high eosinophil counts, potential for those with persistent symptoms.
- Benralizumab for EoE: Achieves high histologic remission rates, need for more biomarkers.
- Omalizumab for Food Allergies: Approved to reduce reactions from accidental exposures, requires regular injections.
- Mavorixafor for WHIM Syndrome: Reduces infection severity and increases white blood cell counts.
- Anti-IL-23 Antibodies: Correlate with severe infections in thymoma patients, potential treatment avenues.
- Allergic Rhinitis in Childhood: Steady increase in prevalence up to age 16, highlights early diagnosis importance.
- Systemic Symptoms in CSU: Common in chronic spontaneous urticaria, necessitates comprehensive management.
- NTLA-2002 for HAE: Gene editing therapy significantly reduces angioedema attacks, promising new treatment. -
In this episode of TransplantRPh, April explores the best places to practice pharmacy in the USA for foreign pharmacy graduates and immigrant pharmacists. Learn about the scope of practice, pay, licensing requirements, support networks, cost of living, taxes, and more. Discover which states offer the best opportunities and environments to advance your pharmacy career. Connect with April via email at [email protected] or follow her on LinkedIn, YouTube (Pharmacist April) , and Instagram (@pharmacistapril) Don’t miss her new e-book with a step-by-step guide on becoming a pharmacist in the USA! https://stan.store/pharmacistapril
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Welcome to TransplantRPh! I’m excited to kick off this journey with you. This week, we dive into the essentials of starting and succeeding in a pharmacy career in the United States.
Join us as we explore the diverse practice areas for pharmacists, from community and hospital settings to clinical, long-term care, academic, government, and beyond. Understanding the broader landscape of the pharmacy profession in the US is crucial for aligning your career goals with industry demands and opportunities.
Pharmacy is a dynamic and versatile field, offering numerous career paths beyond traditional roles. Pharmacists play a crucial role in healthcare, ensuring the safe and effective use of medications. We'll delve into various practice settings and specialized fields where pharmacists can thrive.
**What You’ll Learn:**
1. The different roles and settings for pharmacists in the US.
**Why It Matters:**
Gaining insight into the pharmacy landscape helps align your career aspirations with the evolving needs of the healthcare industry.
Stay tuned for more insights into building a successful pharmacy career in the US. Don’t forget to subscribe for the latest episodes and valuable content!
#TransplantRPh #PharmacyCareer #PharmacyLife #HealthcareProfessionals #CareerGoals #PharmacyEducation #Pharmacist #Healthcare #Podcast -
In this short episode, we discuss about CMV,EBV and BK virus in post kidney transplant patients
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In the short episode, we talk about medication, reconciliation in post kidney transplants.
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Short episode talking about immunosuppressant pearls in post kidney transplant.
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In this episode of TransplantRPh, your guide through the transplant journey, April, the transplant pharmacist, explores the critical topic of herpes zoster prevention and vaccination. Join her as she unravels the complexities of varicella-zoster virus reactivation and the path to safeguarding against shingles. From understanding the nuances of immunocompetent patients to navigating the intricacies of immunocompromised adults, April provides valuable insights into the two types of herpes zoster vaccines. Get ready for a deep dive into the world of immunity, vaccination strategies, and crucial considerations for patients who meet the criteria for herpes zoster vaccination. Stay informed, stay protected—this is TransplantRPh.
Disclaimer: The content provided in this podcast, TransplantRPh, is for educational purposes only. The information shared by April, the transplant pharmacist, is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always consult with your healthcare team, including your physician and pharmacist, for personalized guidance tailored to your unique medical situation. The content is based on general knowledge and is not a replacement for individualized healthcare decisions. Any actions or decisions made based on the information in this podcast are at the listener's discretion. April, the host, and TransplantRPh assume no liability for any outcomes resulting from the use of this information. If you have specific medical concerns or questions, seek guidance from your healthcare professionals. -
Unlock the truth behind immune-boosting supplements in a riveting episode of TransplantRPh with your host, April. As we navigate the ever-expanding world of wellness, we dive deep into a case series study examining 30 immune health dietary supplements. Purchased from Amazon.com, these supplements claim to support or boost the immune system, but do they live up to the label? Join April as she unravels the findings, exposing inaccuracies, misbranding, and the potential risks that may be lurking behind those enticing product claims. Get ready to be informed, empowered, and equipped to make the right choices for your well-being. Tune in to "Transplantrph" and let's decode the secrets of immune-boosting supplements together.
Disclaimer: TransplantRPh offers insightful discussions on various health topics, but it's essential to note that the information provided in this episode is for educational and informational purposes only. We are not providing medical advice, diagnosis, or treatment. The case series study discussed reveals specific findings related to immune health dietary supplements, but individual experiences may vary. Always consult with your healthcare provider before making decisions about dietary supplements or any health-related matters. The views and opinions expressed in this episode are those of the host and guests and do not necessarily reflect the official policy or position of TransplantRPh. Stay informed, stay curious, and prioritize your well-being. -
Podcast Description:
Welcome to TransplantRPh where we untangle the threads of vital health topics, providing you with the knowledge to make informed decisions about your well-being. In this episode, we explore the world of RSV (respiratory syncytial virus) and its impact on adults, uncovering recent vaccine recommendations and crucial insights. Join us as we navigate the complexities of RSV infections, vaccination benefits, and protective measures.
Disclaimer:
The information presented in this podcast is for general informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult with your healthcare provider or a qualified medical professional for personalized advice tailored to your specific health circumstances.
While we strive to provide accurate and up-to-date information, the field of healthcare is dynamic, and new research may impact our understanding of certain topics. The hosts, guests, and producers of this podcast are not responsible for any actions taken based on the information presented, and they do not endorse or guarantee the effectiveness of specific treatments or interventions discussed in the episodes.
By listening to this podcast, you acknowledge and agree that the hosts, guests, and producers are not liable for any direct or indirect consequences resulting from the use of the information provided. Take charge of your health responsibly, and stay informed for a healthier tomorrow. -
Discover how GLP-1 receptor agonists have shown promise in improving glucose control and addressing diabetes-related comorbidities in non-transplant patients. Join us as we break down a retrospective analysis of 17 transplant recipients who initiated GLP-1 receptor agonists, shedding light on their safety, efficacy, and potential impact on weight loss and blood glucose control. We'll explore the concerns surrounding gastrointestinal side effects and the absorption of transplant medications, offering insights into the diverse experiences of these patients.
Stay tuned to learn about the intriguing results and conclusions drawn from this study, suggesting that GLP-1 receptor agonists could be a safe and effective treatment for solid-organ transplant recipients with type 2 diabetes. But, as always, there's more to uncover. The podcast aims to ignite curiosity and encourage a deeper understanding of the evolving landscape of medical science.
Disclaimer:
The information presented in this podcast episode is for general informational purposes only and should not be considered a substitute for professional medical advice, diagnosis, or treatment. The podcast hosts, guests, and producers do not endorse or guarantee the effectiveness of any specific treatment or intervention discussed. Individuals should consult with qualified healthcare professionals for personalized advice tailored to their unique health circumstances. -
In this episode, we unravel the intricacies of four groundbreaking medications—Wegovy, Zepbound, Mounjaro, and Ozempic—designed to address weight management and diabetes. Join us on this enlightening journey as we explore the science behind these medications, their study outcomes, and their potential impact on your health and well-being. From dosage details to how they function in the body, we break down the facts you need to know. Tune in to empower yourself with the knowledge necessary for informed decision-making on your health journey.
Remember, knowledge is a powerful tool, but it's essential to consult with your healthcare professional for personalized advice tailored to your health needs. Let's navigate this intricate terrain of pharmaceutical innovations together.
SUMMARY:
- FDA-Approved Incretin Mimetics:
- Wegovy (semaglutide) and Zepbound (tirzepatide) are FDA-approved for chronic weight loss and maintenance.
- Ozempic (semaglutide) and Mounjaro (tirzepatide) are approved for managing blood glucose in type 2 diabetes, with potential for significant weight loss.
- Usage Conditions:
- All agents are prescribed in conjunction with a reduced-calorie diet and exercise.
- Administration involves self-administered subcutaneous pen injections on a weekly basis.
- Weight Loss Results:
- Semaglutide (Ozempic, Wegovy) demonstrated approximately 15% weight loss in adults.
- Ozempic showed 6-7% weight loss in adults, while Wegovy exhibited a 16.1% BMI reduction in children aged 12 and older.
- Zepbound (tirzepatide) demonstrated up to 52 lb (21%) weight loss in patients without type 2 diabetes.
- Gastrointestinal Side Effects:
- Nausea, diarrhea, decreased appetite, vomiting, constipation, dyspepsia, and abdominal pain may occur.
- Slowly titrating the dose, as recommended by the manufacturer, may help reduce stomach-related side effects.
- Other Side Effects:
- Injection site reactions, allergic reactions, and hair loss are potential side effects.
- FDA Approval Date:
- Zepbound received FDA approval for weight loss on November 8, 2023.
- Caution and Consultation:
- This information does not encompass all aspects of Mounjaro, Ozempic, Wegovy, and Zepbound.
- Review the full patient medication guide and discuss any questions with your doctor or healthcare provider.
Disclaimer: The information provided is for general informational purposes only and should not be considered as professional advice. Always consult with qualified healthcare professionals or specialists for personalized guidance and recommendations tailored to your specific situation. Any reliance on the information provided is at your own risk. -
Join me, April Oliveros, transplant pharmacist at TransplantRPh, as we explore BK virus risks and monitoring post-transplantation. Whether you're a transplant recipient or curious about organ transplants, this video provides insights. Let's unravel the complexities together!
Disclaimer: This video offers general information, not a substitute for professional medical advice. Consult your healthcare provider for personalized guidance. April Oliveros and TransplantRPh do not endorse specific medications or interventions. Viewer discretion advised; actions based on this information are at your own risk. TransplantRPh and April Oliveros are not responsible for consequences. Stay informed and consult your healthcare provider for health concerns. -
Welcome to TransplantRPH, the podcast where we dissect the latest research and breakthroughs in the field of transplantation. Join your host, April Oliveros, as she navigates through complex studies, providing clear insights into the world of organ transplants. From cutting-edge advancements to in-depth explorations, TransplantRPH is your go-to source for staying informed in the ever-evolving landscape of transplantation.
Disclaimer:
TransplantRPH is an educational podcast that discusses research findings and developments in the field of organ transplantation. The content provided is for informational purposes only and should not be considered as medical advice. Always consult with your healthcare professional for personalized guidance based on your specific medical condition. The views and opinions expressed in this podcast belong to the host and guests, not to be taken as endorsements or recommendations. TransplantRPH is not responsible for any consequences resulting from the use of information presented in the episodes.
JAMA Network Open. 2023;6(12):e2349538.doi:10.1001/jamanetworkopen.2023.49538
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2813288?resultClick=24 -
Welcome to TransplantRPH, where we dive deep into the world of abdominal transplantation and pharmaceutical insights. Join your host, April Oliveros, an experienced abdominal transplant pharmacist, as she navigates through the complexities of pharmacy practices in the realm of organ transplantation. From discussing the latest advancements in transplantation to sharing real-life patient stories and expert insights, this podcast aims to be your go-to resource for all things transplant pharmacy. Subscribe now and stay informed about the evolving landscape of abdominal transplantation. Let's transplant knowledge together!
Disclaimer:
The information provided in this podcast is intended for general informational purposes only. It does not constitute professional medical or pharmaceutical advice. Always consult with your healthcare provider or a qualified medical professional for personalized guidance. The views and opinions expressed in this podcast are those of the host and guests, and do not necessarily reflect the official policy or position of any healthcare institution or organization.
https://jamanetwork.com/journals/jama/fullarticle/2805945 -
Welcome to TransplantRPH, the podcast where we explore the intricate world of abdominal transplantation through the lens of pharmacy insights. I'm your host, April, an abdominal transplant pharmacist, and in each episode, we unravel the complexities of medications in the transplant journey.
Join us as we discuss the importance of medications in maintaining immunosuppression, preventing rejection, and ensuring the success of abdominal transplants. From dosage and adherence to managing side effects, we dive deep into the pharmaceutical aspects that contribute to the well-being of transplant recipients.
TransplantRPH is not just about pills; it's about the stories of resilience, the collaboration among healthcare professionals, and the hope that medications bring to those who undergo abdominal transplantation. Whether you're a healthcare professional, a transplant patient, or simply curious about this field, our podcast is here to provide valuable insights and foster understanding.
*Disclaimer: The content presented in TransplantRPH is for educational purposes only and should not be considered as medical advice. Consult with your healthcare provider for personalized guidance.
Subscribe now and join us on this journey through the intricacies of abdominal transplantation and the vital role of pharmacy in this transformative process -
Unlock the secrets of kidney transplantation with TransplantRPh! In this episode, our host April, a seasoned transplant pharmacist, delves into the world of compatibility and its pivotal role in successful kidney transplants. Learn about blood type matching, tissue compatibility, and the evolving landscape of immunotherapy. Stay informed and be a part of the conversation. Follow us on Instagram and Twitter @TransplantRPh for more updates. #KidneyTransplant #Compatibility #TransplantRPh
Feel free to adjust the script as per your preferences, and best of luck with your podcast! -
In this episode of TransplantRPH, April navigates the intricacies of Cytomegalovirus (CMV), an often asymptomatic but potentially severe viral infection. This episode provides a comprehensive understanding of CMV, exploring its impact on various individuals, from the risks for immune-compromised patients to potential complications in pregnant women. Listeners will uncover symptoms, diagnostic procedures, and treatment options, catering to a diverse audience seeking clarity on CMV
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