Episódios
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00:00 Intro 01:30 What are peptides and how are they made 07:20 Safety of peptides 12:52 FDA and peptides 18:45 BPC157 31:10 TB500 37:20 Growth hormone peptides 44:20 Longevity peptides, Epitalon, Melanotan 52:35 Fundamentals of lifestyle 56:45 Preparing for peptide protocolsDr Silvana Laith Instagram: https://www.instagram.com/drsilvanalaith/
Noah Laith Instagram: https://www.instagram.com/thestoicbiohacker/
I Took BPC 157 Peptide for 2 Months and Here's What Happened: https://youtu.be/9qc9dhDDDhc
Order my new book: https://www.amazon.com/dp/B0CW1B2XM1
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Hello, this is a casual livestream. The list is based on my opinionOrder my new book: https://www.amazon.com/dp/B0CW1B2XM1
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Timestamps:
00:00 Intro 00:32 Bon Charge Sponsorship 01:20 Declining Heart Disease Rates 05:10 Biggest Risk Factors of Heart Disease 10:15 What Is Heart Disease and Atherosclerosis 13:55 When Does Atherosclerosis Begin 20:55 Biggest Risk Factors of Heart Disease 27:55 Role of Genetics in Heart Disease 31:50 High vs Low Lipids 39:40 Managing Your Risk Trajectory Over Time 45:30 Lp(a) 52:30 ApoB vs Cholesterol 57:20 Does HDL Reduce the Risk of Heart Disease 59:35 Homocysteine 01:02:55 Does Too Much Exercise Cause Atherosclerosis 01:09:55 Practical Steps to Heart Disease Prevention 01:15:30 Detecting Calcium in the Arteries 01:20:35 Calcified Hard Plaques vs Non-Calcified Plaques 01:22:45 At What Calcium Score Can You Get a Heart AttackDr Paddy Barrett Twitter: https://x.com/paddy_barrett
Dr Paddy Barrett Substack: https://paddybarrett.substack.com/
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Timestamps:
00:00 Introduction 00:37 Twenty since Aubrey coined the Longevity Escape Velocity 11:13 When will we reach Longevity Escape Velocity 16:45 Slowing down aging vs regeneration 19:44 What breakthroughs we need for longevity escape velocity 24:00 Seven types of aging damage that needs to be repaired 24:37 Loss of cells and stem cells 33:57 Regenerating limbs and organs 36:10 Mitochondrial free radical theory of aging 41:15 Intracellular and Extracellular waste products 47:15 How far is gene therapy now? 49:15 Death resistant cells 53:52 Do you need long telomeres 57:15 Extracellular matrix stiffening and glycation 01:00:48 Biggest breakthroughs in the next 5 years 01:04:30 What to do to live until the longevity escape velocityThe Longevity Escape Velocity Foundation: https://www.levf.org/
Aubrey de Grey Twitter: https://x.com/aubreydegrey
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Timestamps:
00:30 Introduction 00:50 What is cancer 04:30 Does everyone have cancer all the time? 06:30 When does cancer become lethal 11:30 Hallmarks of cancer 21:20 Senescent cells vs cancer cells 25:00 Evolutionary purpose of cancer 27:30 Cancer prevention 30:10 Ultra processed food and cancer risk 35:35 Organic vs non-organic food 38:40 What are carcinogens 45:10 Immune function and cancer 48:15 Meat and cancer 51:20 mTOR and cancer 01:02:20 Glucose, Warburg Effect and cancer 01:07:00 Ketones and cancer 01:11:00 Artificial sweeteners 01:16:40 Environmental toxinsDr Joe Zundell YouTube channel: https://www.youtube.com/@dr.joezundell
Dr Joe Zundell Instagram: https://www.instagram.com/dr.joezundell/
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Timestamps:
00:01 Supplements that are bad for the heart 08:45 Will we see someone live to 125 11:56 Bon Charge sponsorship 12:46 Maltodextrin in protein powder 13:59 Hyaluronic acid supplementation and cancer 15:32 Creatine reduces VO2 max 17:55 Limiting factor in losing visceral fat 20:45 Which disease am I most afraid of 25:13 Weighted stretching for muscle growth 28:00 Protein restriction and lifespan 32:22 How to train with joint pain 35:39 How much NAC for 60+ 37:23 How to stimulate appetite 40:47 What's a good VO2 max for womenOrder my new book: https://www.amazon.com/dp/B0CW1B2XM1
Get The Longevity Leap Worksheet: https://www.siimland.co/offers/gX7pV7RF
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Order my new book: https://www.amazon.com/dp/B0CW1B2XM1
Timestamps:
00:37 Omega 3 Health Benefits as of 2024 03:50 Why Are Omega 3 Fats Beneficial 08:57 My New Book The Longevity Leap 09:15 Why Aren't Omega 3s Essential 09:57 What Is the Omega 3 Index 14:45 Is There Risk of Healthy User Bias 17:50 How High Omega 3 Index Is Optimal 26:28 How to Increase Omega 3 Index 29:38 Different Types of Omega 3 Supplements 32:40 Are Omega 3 Supplements Oxidized and Rancid 35:15 How to Choose an Omega 3 Supplement 40:15 Heart Disease and Omega 3s 46:25 Neurodegeneration and Omega 3s 48:00 Omega 6 Fats and Mortality 55:00 How Much Omega 6 Is Too Much 59:48 Omega 9 Fats 01:02:15 How to Store Omega 3 Supplements -
Order my new book: https://www.amazon.com/dp/B0CW1B2XM1
Timestamps:
00:29 Introduction 02:43 Question 1: Death and longevity 11:23 Julie’s advice to Siim 12:58 Meeting likeminded people interested in longevity 17:33 Dave getting stem cells 19:33 Rejuvenation Olympics 22:18 How I share evidence 28:53 Longevity as a sport 40:58 How the Rejuvenation Olympics works 48:28 What’s the best biological age clock 53:58 Telomere length 58:31 How long can we make humans live 01:12:52 Panel about exercise routines 01:19:38 Panel about sleep 01:25:52 Panel about nutrition 01:36:44 Panel about supplements 01:46:44 Best low-hanging fruitsAdam the host's channel: https://youtube.com/@nopara73?si=7z6gKAq6s5vZTT_T
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Timestamps:
00:30 Misconceptions about stem cell therapy 04:20 Different types of stem cells 07:10 Bon Charge sponsorship 07:55 Stem cells and aging 09:00 Studies about stem cell anti-aging effects 13:32 FDA regulations regarding stem cells 25:19 How Joy got into stem cells 36:39 Cost of stem cell therapy 43:40 Process of getting umbilical cord stem cells 49:45 Stem cell procedures 57:55 Finding reliable stem cell clinics 01:02:48 Joy Kong's clinic and contentDr Joy Kong YouTube channel: https://www.youtube.com/@JoyKongMD/featured
Order my new book: https://www.amazon.com/dp/B0CW1B2XM1
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Code LEAP for 15% off the Longevity Leap Bundle: https://donotage.org/longevity-leap-bundle
Timestamps:
00:29 Leigh’s background 06:44 Health benefits of cold exposure and breathwork 09:44 Mammalian dive reflex 11:45 DoNotAge Longevity Leap supplement bundle 13:20 Benefits of breath holds 16:55 How long can you hold your breath for 20:30 Are there benefits to being able to hold your breath for long 25:56 Hyperventilation vs breath holds 34:46 Breathwork exercises for beginners 40:27 How to breathe correctly 45:00 Nasal breathing vs mouth breathing 52:00 How to breathe during exercise 54:45 Leigh’s new bookLeigh Ewin's new book: https://www.leighewin.com/leigh-events/p/re-spiritual-awakening-audiobook-pre-order
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Timestamps:
00:01 Are Too Many Supplements Bad for Organs 03:46 How to Clear Caffeine From the Body 07:00 When Do I Think Longevity Escape Velocity Will Begin 11:05 Bon Charge Sponsorship 11:49 How to Improve Sleep 14:45 What Biomarker I Want to Improve 19:04 mTOR and Longevity 24:05 How to Increase HRV Besides Exercise 26:25 Do I Have Cheat Meals 27:46 Astaxanthin and Testosterone 29:02 Taking 35 Grams of Glycine Per Day 31:09 Thoughts on Pterostilbene for Longevity 32:25 Essential Supplements for Vegans 34:20 Cancer Prevention 35:42 How to Improve Skin Elasticity 36:43 Does Calorie Restriction Decrease PerformanceOrder my new book: https://www.amazon.com/dp/B0CW1B2XM1
Get The Longevity Leap Worksheet: https://www.siimland.co/offers/gX7pV7RF
Join my next retreat at a longevity clinic: https://www.siimland.co/retreat
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Get The Longevity Leap Worksheet: https://www.siimland.co/offers/gX7pV7RF
Order my new book: https://www.amazon.com/dp/B0CW1B2XM1
Timestamps
00:12 Alexis' background 03:00 What's available for regeneration currently 04:37 Alexis’ 3 step process for longevity medicine – Phase 1 09:30 The Longevity Leap Worksheet 10:09 Phase 2 - cleanup 12:35 Evidence for chelation therapies 13:58 Effects of senolytics 18:20 Phase 3 - regeneration 19:39 Exosomes and stem cells 28:09 Can exosomes extend lifespan 33:25 Peptides 39:08 Restoring melatonin levels 42:13 How many stem cells do you have 45:05 Why don't we live to 120 51:30 Can you remove plaque from arteries 56:10 What supplements Alexis takes 01:12:00 Diet and exercise 01:17:28 After the 3 phase planAlexis Ortega MD Instagram: https://www.instagram.com/alexis_ortega_md/
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Get my new book The Longevity Leap: https://www.siimland.co/offers/Mo7aiaAh/
Join our next retreat: https://www.siimland.co/retreat
Timestamps:
00:40 Joe's 7th time at the clinic 01:25 Utilization of amino acids 09:00 What tests is Joe doing frequently 10:29 My new book The Longevity Leap 11:08 Joe on taking 150 supplements per day 22:02 Why Joe takes so many supplements 28:42 How genetics affects homocysteine 33:12 How Joe started coaching Liver King 36:47 Does everyone in the modern world need supplements 46:15 GeneticsJoe Cohen YouTube channel: https://www.youtube.com/@thejoecohenshow
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Timestamps:
01:00 Senescent Cells and Aging 09:18 Bon Charge Sponsorship 10:00 Immune System Aging 15:08 What Triggers Cell Senescence 18:50 How to Measure Cell Senescence 22:58 Senolytic Supplements and Drugs 35:50 mTOR, Rapamycin and Senescence 38:25 Aging and Autoimmunity 46:00 Recent Study on IL-11 and Life Extension 55:00 Mice Living Pathogen Free in LabsMatt Kaeberlein Optispan YouTube Channel: https://www.youtube.com/@optispan
Get my new book The Longevity Leap: https://www.siimland.co/thelongevityleap
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Timestamps:
00:01 Recommended supplements for people in their 40s? 08:44 Three simplest ways to increase VO2 max 13:45 What will you do in your 30s that makes the biggest bang for your buck that is not exercise? 16:42 How to decrease stress levels? Any breath method? Supplements to deal with it? 19:57 I supplement with omega 3 high dose but I eat many nuts as well. Is my omega 3 wasted? 22:34 If you don’t have a sauna does a very hot shower bring the same or near benefits? 25:11 Does sex help increase longevity? 27:52 How did you do a fat loss phase? Lower carbs or fat? 30:42 I’d like to gain the weight healthy. Do you have any recommendations for the food, training? 34:16 Are you planning to start taking rapamycin? 36:24 When is your next retreat to India cause we’re coming 37:28 How did you lower your LDL? 38:54 Top 5 things that improved your sleep 42:42 What oil do you use to fry your sweet potato fries? 43:41 Thoughts on astaxanthin? Daily dose? 44:44 Do you take novos core supplement?Pre-order my new book: https://www.siimland.co/offers/Mo7aiaAhJoin my next retreat at a longevity clinic: https://www.siimland.co/retreat
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Pre-order my new book The Longevity Leap: https://www.siimland.co/offers/Mo7aiaAh/checkout
Timestamps:
00:31 Life Expectancy Trends 03:08 Delay Chronic Diseases 06:26 Longest Living Man In History 10:21 Timeline of Chronic Diseases 12:23 Heart Disease and Neurodegeneration 14:45 Metabolic Syndrome 18:27 Slow Down Decline 22:17 Heart Rate and HRV 24:04 Muscle and Strength 25:35 Cognitive DeclineJoin the Biohacker Summit: https://biohackersummit.com/
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Pre-order my new book The Longevity Leap: https://www.siimland.co/offers/Mo7aiaAh/checkout
Timestamps:
00:56 The Longevity Mix 01:28 Calcium Alpha-Ketoglutarate 03:58 Vitamin C 06:30 Creatine Monohydrate 07:32 Magnesium Citrate 09:18 Glucosamine Sulfate 10:15 Taurine 11:08 Glycine 13:17 Glutathione 14:14 Lysine 15:26 Ashwagandha 16:40 Theanine 17:26 Sodium Hyaluronate 18:42 Essential Softgels 19:05 Vitamin K1 21:00 Vitamin K2 22:20 Astaxanthin 23:35 Lutein and Zeaxanthin 24:25 Lycopene 25:06 Essential Capsules 25:41 Nicotinamide Riboside (NR) 26:40 Spermidine 27:37 Lithium 28:15 Rhodiola Rosea 28:30 CoQ10 29:17 NAC+Ginger+Curcumin 29:20 NAC 30:01 Curcumin 30:41 Ginger 31:34 Red Yeast Rice 32:10 Garlic 33:20 My Final Rating for Blueprint Supplements -
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Timestamps:
00:05 Supplements That Kill Your Gains 03:43 Gelatin Powder Instead of Glycine 05:02 Bon Charge Sponsorship 05:54 Superfoods to Eat Daily 12:54 Key Supplements for 50+ 19:38 How I Treat Elbow Pain 23:35 How Much Vitamin D Is Normal 26:19 After the Basics, Top 3 Things for Longevity 31:30 How to Go From 21% Bodyfat to 12% 34:20 How Much Fruit I Eat 34:59 Are Smartwatches and Fitness Trackers HarmfulPre-order my new book: https://www.siimland.co/offers/Mo7aiaAh
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Timestamps:
02:40 What Is VO2 Max 05:29 Bon Charge Sponsorship 06:20 How to Measure VO2 Max 13:00 How Much VO2 Max for Longevity 18:25 How to Slow Down VO2 Max Decline With Aging 25:15 What Determines VO2 Max 29:42 Does Too Much Exercise Cause Artery Calcification 34:50 Can Exercise Make Up for Bad Sleep 37:40 HIIT Cardio vs Zone 2 Cardio 46:20 How to Know If You're Doing HIIT 50:15 Optimal HIIT Intervals 54:40 How Much Zone 2 Training 57:10 Running and Injuries 01:00:00 Supplements That Increase VO2 Max 01:06:00 How High VO2 Max Is Too HighBrady Holmer Twitter: https://x.com/B_Holmer
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