Episódios
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Relationships are challenging.
In this episode, we explore some of the Autistic phenotype challenges in relationships. We discuss symptoms from criteria A are external and criteria B are internal, and how criteria B complicates the symptoms in criteria A. In addition, Autism is a comparison to social-norms, and this is a problem. Some environments/relationships discussed include peer-to-peer, romantic, and parent-child. To begin, we explain the mechanisms behind the speaker-receiver and the use of conveying speech in socialness.
Before we begin, we cover a brief explanation of Speaker-Receiver and human communication.
Dr. Theresa Regan episode https://youtu.be/aUhIreFd5sw
Autism and Adaptive Responses https://podcasts.apple.com/us/podcast/from-the-spectrum-finding-superpowers-with-autism/id1737499562?i=1000658438095
What is Autism: Criteria A https://podcasts.apple.com/us/podcast/from-the-spectrum-finding-superpowers-with-autism/id1737499562?i=1000651048705
The Roles of Oxytocin and Vasopressin in the Autistic Phenotype https://podcasts.apple.com/us/podcast/from-the-spectrum-finding-superpowers-with-autism/id1737499562?i=1000660031273
(0:00) Intro; Speaker-Receiver explanation when conveying speech
(3:55) Unpredicableness in socialness; black and white thinking and context-dependent and adaptive responses; Metabolic energy/resources; Oxytocin and Serotonin
(7:10) Biology that gives us Autism gives us complications to socialness and relationships; Sex-differences and socialness
(8:40) Criteria A is external, Criteria B is internal; Sensory-Processing
(10:32) B.2 and B.3 implicates socialness
(16:58) Direct social interactions
(22:26) Autism versus social norms; Romantic relationships
(26:51) Do Autistics outgrow Autism?
(28:04) Parenting
(31:30) Cohabitating
(32:28) Wrap Up
(32:45) Reviews/Ratings and contact info
Links: hopp.bio/fromthespectrum
X: https://twitter.com/rps47586
Email: [email protected]
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For today's episode, we speak with Dr. Theresa Regan, PhD & CAS, about adolescents and adults with Autism. Dr. Regan is a neuropsychologist with over 25 years of experience serving adolescents, adults, and seniors in hospital settings. She is a Certified Autism Specialist and the Director of the OSF HealthCare Adult Diagnostic Autism Clinic. Dr. Regan has conducted over 1,000 assessments on adolescents and adults with Autism. Her expertise in brain-behavior relationships, adult and geriatric medical conditions, and autism has provided her with a unique set of qualifications for serving adults with autism.
In addition to her clinical work, Dr. Regan is the author of Understanding Autism and the host of the podcast "Autism in the Adult." During the episode, Dr. Regan shares valuable tools and protocols for Autistics as we learn to navigate various responsibilities such as employment and relationships. Her role as a neuropsychologist offers her insights into alternative approaches beneficial for both Autistics and their friends, family, as well as in employment and educational settings.
Dr. Theresa Regan https://www.adultandgeriatricautism.com
OSF Healthcare https://www2.osfhealthcare.org/providers/theresa-regan-1602000
Autism in the Adult https://open.spotify.com/show/2POoTBvzgPr0yIkU7dmw2m?si=31381356153f4903&nd=1&dlsi=8f401dc6fce54bb5
Understanding Autism https://www.amazon.com/dp/B098KQKZT7?binding=kindle_edition&ref_=ast_author_bsi
0:00 Dr. Theresa Regan
1:42 Journey into Psychology and Autism
7:20 Understanding Autism in Adults
13:39 The Role of Self-Knowledge in Relationships
19:47 Challenges faced by Adults with Autism
25:32 Tools and Protocols for Regulation
31:48 Navigating Employment
37:54 The Importance of Self-Care and Balance
43:35 Resources and Future Direction
55:18 Reviews/Rating and Contact Info
X: https://x.com/rps47586
Hopp: https://www.hopp.bio/fromthespectrum
email: [email protected]
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In this episode, we discuss Autism with Nicole Rincon, PA-C from Rossignol Medical Center. Nicole Rincon is a board-certified Physician Assistant (PA-C) who specializes in Pediatric Special Needs, MAPS (Medical Academy of Pediatric Special Needs), Integrative, and Functional Medicine. At Rossignol Medical Center, she is actively involved in patient care, research, and educational content. Nicole adopts valuable holistic and patient-centered care approaches in her practice.
Nicole also brings a deeply personal perspective to the discussion as a mother of children with regressive Autism. This personal journey has fueled her motivation to explore the complexities of Autism, leading her to Rossignol Medical Center. Prior to this, Nicole spent years in medical weight management, focusing on nutritional counseling and wellness supplementation. This background provides her with unique insights into the metabolic, gastrointestinal, and environmental factors influencing Autism.
Disclaimer: This is not Medical Advice
Nicole Rincon https://www.nicolerincon.com/nicole-rincon
Rossignol Medical Center https://rossignolmedicalcenter.com/doctors/nicole-rincon/
TACA Info: https://tacanow.org/wp-content/uploads/2019/10/F-H-2-Nicole-Rincon-Beginning-Biomed.pdf
TACA Talks: https://www.nicolerincon.com/videos
X: https://x.com/NicoleRinconPA
Publications https://rossignolmedicalcenter.com/articles-publications/#published-2024-2-articles
0:00 Nicole Rincon
2:07 Nicole's Personal and Professional Journey into Medicine and Autism; "Who's the guy in Charge?"
12:30 Understanding Autism Trough Research and Interventions; Regression; Omegas and Toxins
21:56 Functional Medicine Approach to Autism; Rossignol Medical Center
25:07 Introduction to various Folate factors, Folate Receptor Antibodies, and Methylation
30:36 The Role of Mitochondrial Dysfunction and the many Comorbid Conditions of Autism (Autism and X, Y, Z)
36:02 Collaborative Approach at Rossignol Medical Center; Research Insights and Opportunities from Nicole's multiple roles
42:22 Challenges with the Current Medical Paradigm
44:09 Maternal Health and its Impact on Autism
48:34 Investigating Autism Beyond Vaccines
50:59 The Role of Light and Environment in Human Biology; Electrons and Magnetism
53:26 Introduction to Nicole's Comprehensive Evaluation from a Functional Medicine Approach; Understanding the Patient and Upstream Dysfunctions
1:02 Multifactorial Approach
1:05 The Future of Medicine, integrating Functional and Patient Center Care
1:13 Reviews/Ratings and Contact Info
X: https://x.com/rps47586
Hopp: https://www.hopp.bio/fromthespectrum
email: [email protected]
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For today’s episode, we discuss Autism with J.D. Barker. J.D. is a New York Times and International Best-Selling Author. His debut novel, Forsaken, caught the attention of legendary Author, Stephen King, who allowed Barker to use one of his characters from Needful Things for Barker’s debut novel. His writing career took off with The Fourth Monkey, which drew widespread attention, leading to a series of auctions and pre-empts for its publishing rights globally. Barker's style often involves intricate plots that blend psychological depth with supernatural or crime elements, appealing to fans of both horror and thriller genres.
Barker's work expanded when he was approached by Bram Stoker's family to co-author a prequel to Dracula, titled Dracul, utilizing previously unpublished notes by Stoker. Barker is a frequent co-author with legendary writer, James Patterson. Listen to how Barker can create such vivid imagination with the characters he creates. In addition, Barker shares critical information on how he navigates such a prolific and successful writing career, often managing many projects with great efficiency. This episode provides critical insights on how the Autistic Phenotype can strive with their unique superpowers.
J.D. Barker https://jdbarker.com/books/heavy-are-the-stones/
J.D Barker and Christine Daigle's upcoming book in November, Heavy Are the Stones https://www.amazon.com/Heavy-Are-Stones-J-D-Barker-ebook/dp/B0D5RKLYPC/ref=sr_1_1?crid=2TRLN3LUMCEFA&dib=eyJ2IjoiMSJ9.FJj1OgrpA4iJyLa9pHJ9ZQ.GiVjyydPJtKVpMdmN0HupggAyTd0GcjUBJ9l5UUA6xM&dib_tag=se&keywords=heavy+are+the+stones+jd+barker&qid=1728672013&sprefix=jd+barker+heavy%2Caps%2C119&sr=8-1
J.D. Barker Books https://www.amazon.com/s?k=JD+Barker&crid=18DBO8RHA8T05&sprefix=jd+barker%2Caps%2C111&ref=nb_sb_noss_1
X: https://x.com/jdbarker
0:00 JD Barker
2:49 Early Years of Creativity, Books, & Understanding Autism; Trying to Fit-In; Following Rules, Black and White thinking versus Gray
11:43 Superpowers of Writing as a Reflection, Creativity, & Intelligence of the Inner World
15:00 Superpowers of Autism by Creating Catalogs: Patterns, Visual & Thinking in Pictures, & Creating Characters
20:42 Balancing Life with Autism
23:51 The Writing Bout; the Importance of Managing Energy to avoid Burnout
35:42 Focusing on the Process, not the Outcome
39:35 Stephen King's Blessing & Approval of Forsaken; the journey to meet King
41:44 James Patterson Collaborations
43:25 Bram Stoker & the Prequel to Dracula, Dracul; Superpower of the Autistic Brain example
46:11 Recognizing Autism in Children
49:11 Future work
52:42 Review/Ratings & Contact Info
X: https://x.com/rps47586
Hopp: https://www.hopp.bio/fromthespectrum
email: [email protected]
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In this episode, we discuss Autism and the Default Mode Network. According to Lisa Feldman-Barrett, the Default Mode Network has many names because it has been discovered, named, rediscovered, and renamed many times. I do not disagree with the Science regarding Autism and the Default Mode Network. However, I disagree with the Interpretation of the Data. This IS our Default; our preferred state; the core of the Autistic Phenotype.
After listening to this episode and understanding B.3, you can understand MOST of Autism. The only reason you cannot understand ALL of Autism from these two episodes is the amount of Phenotypes branching off of B.3 and our Default Mode. Autism IS preference for ALONENESS and SAMENESS. This minimizes sensations and distractions that interfere with our internal world. This state is NOT abnormal, how society interferes with it makes it abnormal.
If you want more Autistics to ACHIEVE, then understand your interaction, interference, and interpretation of what YOU think Autism is, and that delta determines how much we are prevented in life. This, of course, becomes slightly different the more profound the Autistic Phenotype is with that specific person.
In this episode, we will explore the different brain regions and the goals of these regions as it relates to our phenotypes. We will get into some "Thinking in Picture" and thinking styles. This will be a good time because of a future guest on From the Spectrum Podcast discussing Autism and Creativity. This is exciting for me.
Lisa Feldman-Barrett Core System (DMN) https://lisafeldmanbarrett.com/2017/02/05/core-systems/
0:41 Research at UT-Austin and the Importance of the INFRARED LIGHT study with Autism
5:48 Autism and the Default Mode Network (DMN); Buzzword in Science
7:19 Humans and our Prediction Machine and Sensory Processing; Innate or Learned; Oxytocin in the Autistic Phenotype;
9:36 History of DMN (from Lisa Feldman-Barrett) and the many names; Core Systems
11:58 medial Prefrontal Cortex (covered in many episodes); roles, E/I, connectivity, Internal Calculators
14:45 Posterior Cingulate Cortex (PCC); Self-Referential Thinking, Memory, Attention, Task-Switching and the harms of calling it ADHD
18:03 Angular Gyrus; Language, Sensory Processing "Bee Movie" example, Mental Images, Narratives, Empathy
21:12 Supplementing Relationships
23:36 Sensation-Perception
24:30 Precuneus; Self-Awareness, Episodic Memory, Prediction and Strategic Planning
25:52 Social Cognition; Social Cues and Skills
27:50 Autism and Anxiety- Avoidance, Breathing (Physiology), and Valence (how we feel)
28:48 Internal Calculators; Metabolic Bank Account and Demands
29:26 the DMN is a Misnomer and the Default (tendency, phenotype) of the Autistic
33:04 Reviews/Ratings, Contact Info
X: https://twitter.com/rps47586
Hopp: https://www.hopp.bio/fromthespectrum
email: [email protected]
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For today's episode, we discuss Autism with Dr. Yehezkel Ben-Ari. Dr. Ben-Ari is a pioneer in the field of human development with over five decades of academic and private research. He has over 520 publications with a strong passion for early detection and treatment of brain disorders. His work includes studying Human Development, Autism, Epilepsy, Parkinson's, and Brain Tumors. He is a leader in how science understands the roles GABA and Chloride during early development and the NCCK1 importer and KCC2 exporter during the Excitation/Inhibition shift.
In 1986, he led INSERM Neurobiology and Pathophysiology of Development before shifting to Start-Up private investigation in 2008. He is the founder of Neurocholre, B & A Biomedical, B & A Oncomedical, INMED, and IBEN. Recently, Dr. Ben-Ari has made wonderful contributions towards Autism identification in the Placenta using the work of "Neuroarchaeology" and Machine Learning. Dr. Ben-Ari is the recipient of many awards including Grand Prix de l'INSERM, Grand Prix European Society of Epilepsy, and Grand Prix Gagne Van Heck Belgian National Scientific Research (FNRS), to name a few. His book, The First 1000 Days, will soon have an English version. Treating Autism with Bumetanide is available now.
Dr. Yehezkel Ben-Ari https://www.inmed.fr/en/evenement/en-yehezkel-ben-ari
Neurochlore https://www.neurochlore.fr/en/
Machine Learning https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994821/
Excitatory Actions of GABA https://www.nature.com/articles/nrn920
GABA https://journals.physiology.org/doi/full/10.1152/physrev.00017.2006
Neuro-Archaeology https://pubmed.ncbi.nlm.nih.gov/18951639/e
Books: https://www.amazon.com/s?k=yehezkel+ben-ari&crid=1LZK6JWEBG4NC&sprefix=yehezkel+ben-ari%2Caps%2C196&ref=nb_sb_noss
0:00 Dr. Yehezkel Ben-Ari
3:08 Understanding Autism: Origins and Early Detection
8:08 The Roles of Machine Learning Data Analysis in Identification
14:56 The Impact of Environment and Autism
23:18 Treatment Approaches and Efficacy, Bumetanide, and NKKC1 Inhibitors
31:04 Challenges in Autism Research, including the Genetic Debate, Medical Paradigms, and Decision-Makers
38:00 Future Direction and Innovative Research, Autism in the Placenta and the Environment during Pregnancy
53:56 Wrap Up / Reviews and Ratings, Contact Info
X: https://x.com/rps47586
Hopp: https://www.hopp.bio/fromthespectrum
email: [email protected]
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For today, just a brief introduction to research beginning at UT-Austin, University of Texas at Austin, led by Dr. Francisco Gonzalez-Lima. The study is called: Effects of Transcranial Infrared Light Stimulation on Symptoms of Autism Spectrum Disorder. In the link below, it is Study #2.
Dr. Francisco Gonzalez-Lima https://dellmed.utexas.edu/directory/francisco-gonzalez-lima
Research Link (Study #2) https://labs.la.utexas.edu/gonzalez-lima/participate-in-our-research/
Research Team https://labs.la.utexas.edu/gonzalez-lima/team/
X: https://x.com/rps47586
Hopp: https://www.hopp.bio/fromthespectrum
email: [email protected]
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In this episode, we discuss eye-tracking as an early biomarker for Autism. Eye-tracking, on infants, improve assessment outcomes at young ages, as young as 14-months-old. Adding biomarkers to the assessment process is valuable, and Autism research is beginning to offer more biomarkers. We've covered biomarkers in cellular respiration, serotonin, two studies on 6-week-olds- 1) predicted profound Autism with brain cortical organoids and 2) salience network connectivity. Today, we review four scientific papers on eye-tracking being added to the assessment process.
A valuable consideration is the roles our eyes have on brain development, which we cover as well.
Pierce et al 2019 https://pubmed.ncbi.nlm.nih.gov/31034004/
Wen et al 2022 https://www.nature.com/articles/s41598-022-08102-6
Keehn et al 2024 https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2818669
Early Autism Evaluation (EAE) https://medicine.iu.edu/expertise/indiana-health/access-to-care/autism/care
Rudling et al 2024 https://journals.sagepub.com/doi/full/10.1177/13623613231203037
The Roles of Oxytocin and Vasopressin in the Autistic Phenotype https://www.youtube.com/watch?v=DAtmC-s1_e0
0:00 Intro; 2 studies on 6-week-olds; Eye Development and Brain Development, Opsins
5:23 OCT (Optical Coherence Tomography) scans and Brain predictors, Melanopsin and Choroid Plexus
7:06 Melanin and Melanopsin through the body and biochemistry
8:39 Fruit Tree Example from Dr. Kruse
9:29 Eye-tracking and Autism as a Biomarker; Neuroplasticity- Human's capacity to think; Autism is NEW in human evolution
14:05 Social Attention; Oxytocin- magnocellular and parvocellular; Objects over People; Gaze Following
17:21 Gaze Attention
18:02 Joint Attention
19:12 Studies on Infants; Pierce et al, 2019
25:00 Wen et al, 2022
27:03 Keehn et al, 2024 and Early Autism Evaluations (EAE)
29:25 Rudling et al, 2024
32:15 Wrap-Up/Final Thoughts
34:55 Reviews/Ratings, Contact Info
X: https://x.com/rps47586
Hopp: https://www.hopp.bio/fromthespectrum
email: [email protected]
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For this episode, we discuss the roles and sensitivity of mitochondria with Dr. Richard Frye, MD, PhD. Dr. Frye received an MD and a PhD in Physiology and Biophysics from Georgetown University. He is board certified in Pediatrics, Neurology with special competence in Child Neurology, and as a Certified Principal Investigator. In addition, he has a Masters in Biomedical Sciences and Biostatistics from Drexel University. Dr. Frye has over 300 publications in leading journals and book chapters.
He currently sees patients as a Neurologists and Director of Research at Rossingnol Medical Center and at Neurodevelopmental Precision Medicine. In 2022, Dr. Frye co-founded the Autism Discovery and Treatment Foundation where they are dedicated to discover biomarkers, metabolic endophenotypes, and treatments for neurodevelopemental disorders.
Dr. Frye shares many figures during the conversation so the listener can follow along.
Dr, Richard Frye https://drfryemdphd.com
CV https://wparticles.seek2understand.org/wp-content/uploads/2023/02/DrFryeCVJan2023.pdf
Rossingnol Medical Center Facebook https://www.facebook.com/RossignolMedicalCenter
Neurobiology of Disease 2024 paper https://www.sciencedirect.com/science/article/pii/S0969996124001190?via%3Dihub
Autism and GI, and exploring how changes in Light have major implications (Apple) https://podcasts.apple.com/us/podcast/from-the-spectrum-finding-superpowers-with-autism/id1737499562?i=1000664349495
0:00 Dr. Richard Frye
6:13 Intro into mitochondria & energy production, various disease & dysfunction
11:16 Mitochondrial DNA, sensitivity, and the roles with epigenetics
16:16 Biomarkers of mitochondrial dysfunction, delicate delivery (space and time) into the electron transport chain
20:58 Cytochrome C Oxidase (complex IV); Carnitine, Fat, and Creatine
26:57 Molecules connected to aging & cellular respiration, environemental signals implicating mitochondria
30:26 Terrible Trio: oxidative stress, mitochondria dysfunction, immune/inflammation, DAMPS & inflammation
34:29 Environmental risks for the Embryo, overreactivity of mitochondria (200%) and physiological insults and regression
42:50 Tryptophan (aromatic amino acid), NAD, and Gastrointestinal biosynthesis
45:52 Light as an environmental change factoring into the Autistic Phenotype, Infant Tree and Adult Tree examples; Vitamin D (skin & brain are connected through Neuroectoderm)
54:54 Future Research
59:58 Wrap up, Reviews/Ratings
X: https://twitter.com/rps47586
Hopp: https://www.hopp.bio/fromthespectrum
email: [email protected]
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In this episode, we discuss the mitochondria. You know mitochondria as the "powerhouse" of the cell, but this biological process is biophysics meeting biochemistry. We discuss glycolysis, the TCA cycle (or Citric Acid cycle or Krebs cycle), and Oxidative Phosphorylation. This discussion goes deep inside the atomic molecular level with electrons and protons. Hang in there with the discussion and topic of Autism and understanding of the generational link to a loss of electrons.
Jack Kruse https://www.patreon.com/DrJackKruse/posts
Glycolysis https://www.ncbi.nlm.nih.gov/books/NBK470170/#:~:text=Glycolysis%20is%20a%20central%20metabolic,use%20in%20other%20metabolic%20pathways.
Citric Acid cycle https://en.wikipedia.org/wiki/Citric_acid_cycle
Oxidative Phosphorylation https://en.wikipedia.org/wiki/Oxidative_phosphorylation
0:00 Intro; Light, water, magnetism; The "powerhouse" and understanding of healthy living organisms and different cell types; Photosynthesis and Cell Respiration
4:11 Prokaryotes, Eukaryotes, and Cytochrome C Oxidase (CCO)
6:53 Mitochondria and Cellular Respiration 1) Glycolysis, 2) Citric Acid cycle, and 3) Oxidative Phosphorylation (OXPHOS)
8:25 Glycolysis
10:03 Citric Acid cycle
12:02 OXPHOS
13:51 Cytochrome I
15:07 Cytochrome II
16:08 Cytochrome III
17:10 Cytochrome IV and creating water
19:56 Not all water is equal/same; Aging; Light and Melanin and Rates of Autism
29:20 Cytochrome V and ATPase; Chromophores
33:56 Evolution and losing electrons; Autism and modern health complications
37:50 Environmental signals due DNA sequencing; Autism research and Genetic studies
40:23 Reviews/Ratings and contact info
X: https://twitter.com/rps47586
Hopp: https://www.hopp.bio/fromthespectrum
email: [email protected]
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In this episode, we challenge the modern trend of Autism and ADHD comorbid diagnosis. We will use children from Kanner and Asperger to show these so-called ADHD symptoms are simply parts of the Autistic Phenotype. However, society finds it easier to lump these two conditions together, and we question why. We review both, the inattentive criteria and the hyperactivity and impulsivity of ADHD and explain when the Autistic phenotype exhibit these conditions.
The criteria for ADHD are downstream behaviors seen across multiple reasons and act as a collect-all. I did not say ADHD does not exist, but I do say Autism and ADHD existing simultaneously seems unlikely if you really understand the phenotypes. Might it just be easier for society to lump these together instead of challenging the differences?
B.3 and Inattention are complete opposites. Hyperactivity and Impulsivity can show up when anyone is in the wrong or horrible environment.
Autism and ADHD https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8918663/
Leo Kanner http://www.autismtruths.org/pdf/Autistic%20Disturbances%20of%20Affective%20Contact%20-%20Leo%20Kanner.pdf
Hans Asperger https://psycnet.apa.org/record/1992-97284-002
0:00 Intro; Brief Note on how environmental signals such as electromagnetic fields (EMF, i.e., Light) informs the genes on how to respond, and how disease manifests
2:51 Autism and ADHD; Neurodiversity; and some problems in society
7:58 Core of Autism- B.3, and Donald Triplett example; B.2 and Social Communication
13:27 Autistic Phenotypes
19:01 ADHD Phenotypes
21:41 Specifiers and Lumping Contrasting Phenotypes
33:18 Medication and ODD (Oppositional Defiant Disorder) Rant
35:42 Autism conundrum with ADHD
38:45 Reviews/Ratings and Contact Info
Hopp: https://www.hopp.bio/fromthespectrum
X: https://twitter.com/rps47586
email: [email protected]
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My guest today is Jonathan Mitchell. Jonathan is a senior citizen Autistic, Author of numerous novels and blogs, and stands up for the purpose of Autism. His blog, Autism Gadfly, provides perspectives of Autism otherwise not considered by the lay-public or researchers in Autism. Jonathan's views have been mentioned in Newsweek, NPR, Autism Daily Newscast, and HuffPost.
Jonathan was born in 1955 in Los Angeles. We discuss his experience at an early age including psychoanalytic therapy, psychological assessment, and troubles through education. Eventually, Jonathan and his family learned about Autism while on a trip to the East. Jonathan faced many challenges through his education in different schools beginning in kindergarten. However, Jonathan graduated from UCLA with a bachelors of arts in psychology.
We also discuss challenges in professional and personal life as an adult where he faced various barriers. In the early 2000s, when the internet allowed for different communication platforms, Jonathan began to call out things wrong in Autism. In addition, he carries a loud voice for a cure/treatment for Autism. Recently, you can find him on X as he continues to be a voice for the Autistic community.
The Mu Rhythm Bluff https://www.amazon.com/Mu-Rhythm-Bluff-Jonathan-Mitchell-ebook/dp/B00BQN84GM/ref=sr_1_1?crid=2UHATAWKAT5YA&dib=eyJ2IjoiMSJ9.eocnp6hSIjLZqAuzxnIcPw.vv03H-Vx-BeqtHx4_dYo4W6QomZdOkuZ4JEBPgbA-IQ&dib_tag=se&keywords=the+mu+rhythm+bluff&qid=1724157644&sprefix=the+mu+rhy%2Caps%2C104&sr=8-1
X: https://twitter.com/autismgadfly
Jonathan Mitchell website http://www.jonathans-stories.com
Wikipedia https://en.wikipedia.org/wiki/Jonathan_Mitchell_(writer)
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Hans Asperger called the children "little professors"- This is Autism.
In this episode, we explore criteria B.3, which is the core of Autism. Donald Triplett's father's first sentence to Leo Kanner- He seems self-satisfied.
Leo Kanner http://www.autismtruths.org/pdf/Autistic%20Disturbances%20of%20Affective%20Contact%20-%20Leo%20Kanner.pdf
Hans Asperger https://psycnet.apa.org/record/1992-97284-002
Erwin Schrödinger https://en.wikipedia.org/wiki/Erwin_Schrödinger
0:00 Intro, Erwin Schrödinger and Leo Kanner; Light gives Life to Cells
2:29 B.3
5:15 Hans Asperger, Autist
7:19 Leo Kanner
8:31 Paths to Superpowers; Autism and Education; Medicine and Charles Sidney Burwell
13:50 Personal Experiences; Vietnam War; B.2 complications with B.3
15:22 Baseball Game and Probability
16:52 Adult Examples
17:55 1950s and Novel- example of Abnormal B.3; Thinking in Pictures and Supplementing Relationships
21:29 Disruptions from unplanned or outside interference; Medication Approach and Warning
23:36 Unusual Objects; ADHD prep; Finding interests in Life
26:31 Check-Out lanes and Autism; Self-Satisified- This is Autism
28:53 Circumscribed
31:36 Perseverative; The Nervous System
35:44 Bible; Inner-focus using B.3 as a Superpower and directing focus
39:16 Dogs and Snakes
39:50 Autistic Phenotype and B.3 at the Center
40:30 Reviews/Ratings and Contact Info
X: https://twitter.com/rps47586
Hopp: https://hopp.bio/fromthespectrum
email: [email protected]
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In this episode, we explore typical topics with Autism research and try to understand the purpose. Autism research is confounding, and maybe, lacks direction. We offer a research suggestion based on the most plausible cause of Autism- the new modern day environmental factor- Artificial Light. Remember, Autism just shows up, so it makes sense to send the mother and father back to an environment pre-Autism.
Quantum Biology https://www.patreon.com/DrJackKruse/posts
Photobiological Implications of Folate https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862485/
B9 (folate) and B12 (cobalamin) are Photoreceptors, too.
0:00 Autism Research Direction and missing the beginning; Is it Click-Bait?; Confounding
3:30 Changes in Light and the Full Spectrum; the number of Genes involved with Autism Research
5:07 Genetic Variants, Copy Number, Duplications, Deletions
7:04 Gene-Envrionment Interaction; MTHFR; Methylation, Myelin
13:03 Brain Connectivity and Neurobiology
13:55 Socio-Environmental/Socioeconomic; Robert Sapolsky
14:25 Early Diagnosis and Bio-markers
14:47 Comorbid Conditions
16:05 Personalized Interventions
16:27 Medications and the PROFIT MILL
18:36 Today's Purpose; Parental Melanin, Artificial Light, and nnEMF
19:30 Research Idea with 3 Groups and Returning the Environment before Autism magically shows up
25:17 Shift-Work Warning
26:20 Back to Autism; Amish
29:07 Reviews/Ratings, Contact Info
X: https://twitter.com/rps47586
Hopp: hopp.bio/fromthespectrum
email: [email protected]
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In the episode, we will explore a common problem with Autism- the Gastrointestinal Tract. The one consistent finding with Autism and GI is a problem exists. However, research on complicated in these complicated and complex areas of human biology despite what appears to be tight controls in the studies. However, one crucial component is missing- Light. In this episode, we will cover how biology structures order from the light input and the chaos from the environment.
Major Areas include Enterochromaffin Cells, Serotonin, Aromatic Amino Acids, Vitamin D, Enteric Nervous System, the endocrine systems, and the Hypothalamic-Pitutary-Adrenal Axis.
Cause of Autism: https://podcasts.apple.com/us/podcast/from-the-spectrum-finding-superpowers-with-autism/id1737499562?i=1000662271496
Su study: https://www.nature.com/articles/s41564-024-01739-1
Sunlight and Vitamin D: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897598/
Multi-Axis-Meta-Analysis https://www.nature.com/articles/s41598-022-21327-9
Quantum Engineering 33, 54, and 55 https://www.patreon.com/DrJackKruse/posts
(0:00) Autism and the GI Tract; inconsistent research; Order versus Chaos- Light and Environment and Health Conditions
(3:10) The GI Tract; Gut-Brain Axis; Gut Microbiome and Various Nervous Systems
(6:22) POMC; HPA; Stress example
(8:19) Common Autism problems in the GI
(9:23) Enterochromaffin Cells; Serotonin; Immune and Inflammation
(14:09) Melanin/POMC; Clock-Timing; Omentum
(16:31) Real-life Acute GI Fix; Bacteria makes Dopamine in the Gut
(19:04) Vitamin D Receptors and more Clock-Timing
(22:13) Obesity and Autism connection? (uncoupled systems); Biosynthesis of Vit D and specific Wavelength of Light with Shared Biological Processes- DNA, RNA, Aromatic Amino Acids
(24:33) Avoiding UV Light implications
(26:18) Scientific Literature; Archaea, Bacteria, Fungi, Virus; "confounding" data
(30:03) Ubiquinol-7, COQ10, Thiamine Diphosphate; TCA cycles
(32:38) Controls (plural) in Research and lack of Control (singular); LIGHT is GREATER than FOOD
(38:27) Reviews/Ratings and Contact Info
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In this episode, we explore Autism developing in the embryo. We will review a couple Scientific papers discussing specific time frames of development within the embryo based on each trimester and specific cellular abnormal processes occurring. We will connect previous biological and environmental components and how it influences the creation of Autism and previous episodes of From the Spectrum podcast.
Remember in the Cause of Autism episode- Light, Water, Magnetism, Periodic Elements, Vitamins, and Proteins because they are involved. During the episode, we review risk-genes and how this could be the wrong direction for Autism research. As a counter, I provide where research and funding needs to focus- pregnancy.
Cause of Autism https://podcasts.apple.com/us/podcast/from-the-spectrum-finding-superpowers-with-autism/id1737499562?i=1000662271496
Eric Courchesne https://profiles.ucsd.edu/eric.courchesne
Prenatal Origins of ASD: The When, What, and How of ASD Development https://www.cell.com/trends/neurosciences/fulltext/S0166-2236(20)30051-5?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0166223620300515%3Fshowall%3Dtrue
The ASD Living Biology: from cell proliferation to clinical phenotype https://www.nature.com/articles/s41380-018-0056-y
Leukocytes and Melanin Pigmentation https://core.ac.uk/download/pdf/81931995.pdf
mTOR and PTEN https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743803/
Cancer Drug for "Autism" https://neurosciencenews.com/asd-cognition-cancer-pharmacology-26481/
0:00 Autism and the Embryo; Review of previous developmental milestones, and the processes and "ingredients" used in our Biology
5:45 Cellular processes; ASD Living Biology; becoming the complex living organism
8:17 1st Trimester: Proliferation, neurogenesis, migration
8:46 2nd Trimester: Neurite overgrowth, synaptogenesis and synaptic function
9:12 3rd Trimester: Neural networks
9:33 Epoch 1 and 2
13:04 Scientific Literature; risk-genes; send research and funding to pregnancy
17:57 Abnormal brain development in the embryo
21:39 Excitation and the risk-genes and consequences to the Nervous System
24:36 Be cautious of research direction; MEDICATION and MEDICAL PARADIGM RANT
29:32 Connecting Light and Abnormal Development across the Body- Example Melanin and Leukocytes
33:12 Recap on the Past 3 episodes
36:00 Reviews/Ratings and Contact Info
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In this episode, we explore some critical dates and understanding of Autism. We will time travel from 1911 to 2024 with a goal of understanding why the sharp increase in Autism diagnosis of late. We review the closeness of schizophrenia and the separation from schizophrenia. In addition, we will review Autism becoming a separate diagnosis in the DSMs from the 1980s and review the closeness of Vaccines and Assessment Standardization that parallels this time. Hopefully, some consideration about the rates of Autism are presented.
Top Revenue Business Types- Not good. https://www.ibisworld.com/united-states/industry-trends/biggest-industries-by-revenue/
Bayh-Dole Act https://www.govinfo.gov/content/pkg/USCODE-2011-title35/html/USCODE-2011-title35-partII-chap18.htm
How Autism became Autism https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757918/#bibr56-0952695113484320
Eugon Bleuler DEMENTIA PRAECOX OR THE GROUP OF SCHIZOPHRENIAS https://philpapers.org/archive/BLEDPO-2.pdf
Dr. Catherine Lord https://podcasts.apple.com/us/podcast/from-the-spectrum-finding-superpowers-with-autism/id1737499562?i=1000659246090
(0:00) Intro, Classifications, Symptoms, Schizophrenia, DSM, Assessments, Vaccines and Bayh-Dole Act
(3:21) 1911; Twilight Peaks; Psychoanalysis; Eugon Bleuler; Early Autism
(10:37) 1959- Separating from Schizophrenia; Generational Lineage; Visual Imagery; Communication Problems are noticed
(14:21) The DSM and the Development of Autism Diagnosis
(17:32) Assessments becoming Standardized
(20:22) Vaccines and the Bayh-Dole Act of 1980; Vaccine Schedule and Centralized Medicine and Revenue
(25:06) 1980s-2000 emergence of Diagnosis and Assessments; Rates of Autism and Explainations
(30:03) Reviews/Ratings and Contact Info
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Autism just magically shows up.
In this episode, we explore neuroplasiticity in our biology for one common environmental change- Light. Please consider 1) Critical Thinking and 2) Curiosity as we travel upstream in the biological implications causing Autism. In addition, we will explore other common health conditions related to Light. These health conditions are dementia, type 1 diabetes, obesity, type 2 diabetes, cancer, and cardiovascular diseases.
The episode will discuss light as an electromagnetic strip and how our biology uses this energy. We discuss the embryo, neuroectoderm (brain and skin), proteins being wide-band gap semiconductors, photoelectric effect, cytochromes and mitochondria, chromophores, and related topics.
"... I realized that all biochemistry is the bridesmaid to physics. I then realized that physics are how the business of cells gets completed. Light is the biophysical levers that control substrate level biochemistry in cells." - Dr. Jack Kruse
(Start here) Regenerative Health with Dr. Max Guhlane and Dr. Jack Kruse https://www.youtube.com/watch?v=Ln3WszTq0uA
Tetragrammaton with Rick Rubin, Jack Kruse, and Bill Gifford https://www.youtube.com/watch?v=EHe78j9UrMI
Tetragrammaton with Rick Rubin, Jack Kruse, and Andrew Huberman https://www.youtube.com/watch?v=oK9_j6fa2P4
Decentralized is the way (The Status Quo is NO GOOD) https://www.youtube.com/watch?v=VO4JwdXuXXs
Tryptophan Biosynthesis https://faseb.onlinelibrary.wiley.com/doi/epdf/10.1096/fj.04-2079rev
Autism and Vit Bs and Serotonin https://www.patreon.com/posts/quantum-19-74498277
Autism and Melanin https://www.patreon.com/posts/quantum-45-83724567
Regions of Interest:
Atoms,
Aromatic Amino Acids,
Artificial Light,
Chromophores,
Cytochromes,
Electromagnetic,
Embryo,
Folate Acid (and Folic Acid)
Sunlight,
Melanin (Neuromelanin),
Melanocytes,
Melanogenesis,
Melanopsin,
Mitochondria,
Neuroectoderm,
Neuroplasticity,
Periodic Elements,
Photoelectric Effect,
Pro-opiomelanocortin (POMC)
Proteins (wide-band gap semiconductors),
Serotonin,
Tryptophan Hydroxylase 1 and 2,
Vitamins A, b9 (Folate/Folic Acids), B12, and D,
Water
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In this episode, we discuss Autism with Dr. Leanna Hernandez. Dr. Hernandez is an Assistant Professor in the Department of Psychiatry and Biobehavioral Sciences at UCLA and director of the Hernandez Lab. She is a member of UCLA’s Center for Autism Research and Treatment, Center for Neurobehavioral Genetics, and the Brain Research Institute, and serves as Co-Director of the Genetics, Genomics, and Informatics Core for UCLA’s Intellectual and Developmental Disabilities Research Center.
Hernandez Lab https://www.hernandezlabucla.org
Additive effects of oxytocin receptor gene polymorphisms on reward circuitry in youth with autism https://www.nature.com/articles/mp2016209
Imaging-genetics of sex differences in ASD: distinct effects of OXTR variants on brain connectivity https://www.nature.com/articles/s41398-020-0750-9
Oxytocin and Vasopressin and the Autistic Phenotype https://podcasts.apple.com/us/podcast/from-the-spectrum-finding-superpowers-with-autism/id1737499562?i=1000660031273 https://www.youtube.com/watch?v=DAtmC-s1_e0
(0:00) Intro; Dr. Leanna Hernandez
(2:24) Autistic Phenotypes
(4:13) Dr. Hernandez education journey into Autism and the Hernandez Lab
(9:03) 2017 Paper Oxytocin Receptor Gene, Common Genetic Variance, Single Nucleotide Polymorphisms (SNP), and Reward and Social Processing and the Nucleus Accumbens (NAc)
(15:10) Differences in Brain Connectivity between Autistics and Non-Autistics
(20:06) Social Cognition, Boy Bias in Autism; GENDAAR Consortium and Sex- and Diagnosis-Differences
(21:48) GENDAAR
(22:45) Boys versus Girls Connectivity involving the NAc with and without Autism
(25:38) Different Connectivity correlated with Different ADOS scores for Repetitive Behaviors
(26:35) Female Protective Effect for Autism; Camouflaging/Masking
(30:19) The Assessment process for Girls and the Oxytocin Receptor Gene Sex Differences and Socialness and understanding the Boy Bias
(32:48) Current Research and a Genome Wide approach and Polygenic Risk Scores
(35:10) Oxytocin and Excitation/Inhibition
(37:08) Sharing Information and Current Research
(41:45) The Future of Autism Research
(45:48) Reviews/Ratings and Contact Info
email: [email protected]
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We expand on a critical network discussed in the Autism and Adaptive Responses episode. The biology that gives us Autism, gives us a condition the outside world is chaotic. The trade off is our inner world is comfortable. See criteria B.3.
The Salience Network is used to determine what we send our attention to as we orient ourselves with the outside world. You can see this in Autism versus Non-Autism. Autistics orient to single objects or single interests more than multiple objects or interests. That's Criteria B of Autism- Restricted, Repetitive Interests, Behaviors, or Activities.
In Autism, the Salience Network connects to different regions compared to Non-Autism, and this is shown at Six-Weeks-Old. And, this implicates our Social Attention and Social Motivation. Remember Hans Aspergers called the children "little professors" because Autism provides a path of Superpowers based on those fixated interests that are "abnormal in intensity or focus."
Covered Here. Also, we prepare for another discussion with a leading scientist from UCLA.
Study on Six-Week-Old https://www.nature.com/articles/s42003-024-06016-9
GENDAAR https://pubmed.ncbi.nlm.nih.gov/34050743/
(0:00) Intro; Human's Capacity to Think; the Salience Network and the NAc
(2:56) Insula
(4:47) Defining the Salience Network and Salience Detection; getting "hijacked" and metabolic bank account
(7:42) the Biology that gives us Autism causes a Chaotic outside world
(9:00) Returning to Six-week-olds and the Salience Network
(10:28) The Prefrontal Cortex and Human Cortex quiets things so we can properly evaluate things
(13:52) Salience Connections of six-week-olds; social attention at 3-12 months; Autistic traits at 12 months
(17:40) Sex-and-Diagnosis Differences; GENDAAR study using 8-17 year olds; Salience Network and Sensorimotor and Repetitive Behaviors
(20:47) Second Key Finding and possible cause of Boys Bias with Autism
(21:30) The Nucleus Accumbens- Reward Hub; Two Parts; shell and core
(25:20) Preparing for a future episode
(30:27) Reviews/Ratings and Contact Info
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