Episódios

  • We tackle ethics, organoid intelligence and will we ever stop using animals?
    Watch the video here too.

    00:01:03,59: Introducing our special guest Professor Thomas Hartung from the Johns Hopkins Bloomberg School of Public Health.

    00:01:39,03: Marianna and Stephen talk about their extensive travels this month. Includes wonderful meeting at Yale Medical School where there's a lot of people and lots of technologies of organoids and spatial transcriptomics that are really advancing in urological research and teaching young scientists at the Xerox summer school for organ on chip systems in Tubingen.

    00:05:20,59: Thomas Hartung, tells us about his background, interests and more and exciting new opportunities.

    00:09:14,71: Now we talk about ethics in using organoids and organ on a chips, a very big area and a hot topic inc: Intellectual property, regulation, consent, approvals, living donors, data ownership and need for clarity, organoid intelligence and more.

    00:21:17,66: We take a look at some of the reasons and meaning behind evidence based shifts to animal alternatives in research and its challenges. We then look at and discuss examples of why another can't
    represent a human? Will we ever stop using research animals? And how can a simple organoid really replace a big animal? Memory, learning and cognition with organoid intelligence?

    00:40:13,31: We pose the question; What do you see as the biggest obstacle science faces in adopting non animal techniques and what can be done to overcome them? Us and the next generation learning to and design our experiments in a different way using MPS tools rather than animal models. Show in a human complex in vitro system.

    00:44:26,67: Demonstrating with objective data what we can get and what we can't get from animals.

    00:45:20,06: I'm really loving this! The shift towards alternatives to
    animals is also a part of a larger part of society and where we are in the world. We discuss the economic costs, the maths of the research and impact seen.

    00:48:30,26: Quick recap on the ‘3Rs’ Reduction, Refinement, Replacement in practice.

    00:50:18,78: The ethics of AI and potential consciousness of neural organised chips and organoid intelligence. What exactly is organoid intelligence? Are these terms which have meaning in everyday life, intelligence or self-awareness, consciousness relevant? When does intelligence start?

    00:57:08,51: Harrison Ford in the ‘Blade Runner’ and ‘Humanoids’.

    01:04:35,87: Can we use brain organoids today for testing drugs or
    other stimuli? Let's talk about the ethics of it.

    01:14:14,38: Wrap up, The Beatles, conferences coming up, beer, guitar and pizza.

    Visit the HOME of the Podcast here: WORC.Community

  • The WORC.Community podcast at the free to join network for organoid, organ-on-a-chip & NAM researchers!

    Research is better connected, FREE join the WORC.Community today!
    Latest news, papers, webinars, technologies and more.

    Proud supporters of WORD+2025 The event for both Organoid & Organ-on-a-chip Researchers!' 11th to 13th February 2025, Cambridge, U.K!

    Visit the HOME of the Podcast here: WORC.Community

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  • The WORC.Community podcast at the free to join network for organoid, organ-on-a-chip & NAM researchers!

    Research is better connected, FREE join the WORC.Community today!
    Latest news, papers, webinars, technologies and more.

    Proud supporters of WORD+2025 The event for both Organoid & Organ-on-a-chip Researchers!' 11th to 13th February 2025, Cambridge, U.K!

    Visit the HOME of the Podcast here: WORC.Community

  • The WORC.Community podcast at the free to join network for organoid, organ-on-a-chip & NAM researchers!

    Research is better connected, FREE join the WORC.Community today!
    Latest news, papers, webinars, technologies and more. Proud supporters of WORD+2025 The event for both Organoid & Organ-on-a-chip Researchers!' 11th to 13th February 2025, Cambridge, U.K!

    Jump to these highlights:

    2mins: back ground of hosts and why and how did you get into organoid and organ-on-a-chip research?9min30s: What are organoids and organ-on-a-chips, why and how are they being used and analysed in research?18min15s: What is driving organoid and organ-on-a-chip research?25mins: How trustworthy is the data?30mins20s: What research has stood out the last few months?35mins45s: Consequences of 'Hype in research/media' how should you manage them?42mins15s: Media reporting and interpretation of quotes and context!44min15s: Funding- drops and returns and media impact.50mins40s: Recap of organoids and work that has to be done, hot topics for next podcast; standardisation, ethics, usage, multi-disciplinary research and sharing of information- that's just to begin with!52mins58s: Where to meet our hosts this month-come day hello!


    Meet Marianna this month at:

    https://ursonline.org/

    https://www.aacr.org/meeting/aacr-special-conference-pancreatic-cancer-2024/

    https://www.ibcnweb.com/2024-ibcn-meeting/

    EV15_23-24SETT2024_ROME.pdf (mitcongressi.it)

    Meet Steven this month at:

    https://isc2024.org/

    https://euroocs.eu/summer-school/

    https://nordic-innovation-fair-2024.b2match.io/page-2441

    https://informaconnect.com/nordic-life-science-2024/

    Steven discussed this paper:

    https://www.worc.community/documents/roadblocks-confronting-widespread-dissemination-and-deployment-of-organs-on-chips

    Visit the HOME of the Podcast here: WORC.Community