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My guest today is Dr. Kristen Lyall, ScD. Dr. Lyall received a Doctor of Science in Epidemiology from Harvard School of Public Health. During her postdoctoral training, she received training in Nutrient Science at Harvard and Pediatric Epidemiology at UC-Davis MIND Institute's Autism Research Training Program. Currently, Dr. Lyall is an Associate Professor at Drexel University's A.J. Drexel Autism Institute – Modifiable Risk Factors Program.
The overarching goal of the Modifiable Risk Factors program is to identify factors that can be changed to prevent or mitigate the adverse effects associated with Autism, thereby potentially improving outcomes for individuals and informing public health policy and practice. Dr. Lyall's expertise provides actionable tools for listeners to understand the environmental risks of Autism. By the end of the episode, we hope you gain insight into the identified modifiable risk factors for Autism.
Dr. Kristen Lyall: https://drexel.edu/autisminstitute/about/our-team/all-staff/Kristen-Lyall/
Dr. Lyall publications link: https://pubmed.ncbi.nlm.nih.gov/?term=Kristen%20Lyall&sort=pubdate
ECHO: https://echochildren.org
Fish not Supplements: https://echochildren.org/research-summaries/fish-but-not-supplements-consumed-in-pregnancy-associated-with-lower-rates-of-autism-diagnosis-and-related-traits-echo-cohort-study-finds/
Other Resources:
Biological Energy: Quantum Mechanisms, Water, DHA, and NF-kB (Autism is a loss of energy- electrons, photons, protons)
https://youtu.be/2-IA_gunXbw
0:00 Dr. Kristen Lyall
2:30 Her Journey into Epidemiology & Autism
7:50 The Role of Epidemiology & Autism
12:15 Modifiable Risk Factors
17:32 Dietary Influences on Autism Risk; Eat more FISH (DHA!)
22:53 Assessing Exposure & Risk Factors
32:35 Immune & Hormonal Factors in Autism; Cytokines & Inflammation
39:17 The Impact of Acute Events during Pregnancy
44:45 Air Pollution & its Effects in Neurodevelopment; Oxidative Stress
48:14 Current & Future Research; ECHO & EARLI
56:34 Reviews/Ratings, Contact Info
X: https://x.com/rps47586
YouTube: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuA
Hopp: https://www.hopp.bio/fromthespectrum
email: [email protected]
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In this brief episode, we discuss keeping up in the classroom during teacher lecture. Specifically, we discuss the delays in sensory processing, taking notes, visual thinking, and some challenges with keeping up. This is a pressing issue for Autistics, and in my opinion, education needs to do better for the Autistic phenotype.
Autism and Education https://youtu.be/zQpNtvS-tWw
X: https://x.com/rps47586
Hopp: https://www.hopp.bio/fromthespectrum
email: [email protected]
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For today's episode, we discussing transferring energy from the environment across our biology. We discuss a few quantum theories, atoms, molecules, water, DHA, and NF-kB. Life on Earth is driven by energy from the environment, and this could be missed with humans, and especially with developmental problems like Autism.
Water Podcast 1: Rubin, Kruse, Huberman https://www.youtube.com/watch?v=0lBAcUMGIeI&t=43s
Water Podcast 2: Gulhane and Kruse (Light changes the Physics of Water !) https://www.youtube.com/watch?v=l9Ubguvfpys
Water Podcast 3: Gulhane and Kruse https://www.youtube.com/watch?v=W5w0WainlMM
https://www.plefa.com/article/S0952-3278(12)00147-0/abstract
https://pmc.ncbi.nlm.nih.gov/articles/PMC5793004/#:~:text=Electrons%20exist%20in%20all%20matter,role%20in%20oxidation%2Dreduction%20reactions.
Quantum-coherent energy transfer: implications for biology and new energy technologies https://pmc.ncbi.nlm.nih.gov/articles/PMC3385675/#:~:text=In%20the%20simplest%20picture%2C%20quantum,transport%20at%20the%20molecular%20scale.
Quantum cognition: The possibility of processing with nuclear spins in the brain https://www.sciencedirect.com/science/article/abs/pii/S0003491615003243
Role of semiconductivity and ion transport in the electrical conduction of melanin https://www.pnas.org/doi/10.1073/pnas.1119948109
0:00 Intro
0:40 Quantum Biology, Coherence, Thermodynamics, Water, DHA, NF-kB, and transferring energy - Atoms & Molecules
2:00 Oxygen and CCO; Mitochondria
3:55 Quantum Biology; Environments influence Atoms & Molecules
5:50 Coherence & States; Light guides Life on Earth; Light provides Energy after it hits Matter
7:16 Modern Human Environments
7:41 Quantum Thermodynamics; Melanin, Electrons; Rules
9:03 Biophotons, Photons and Lux; Seasonal Impact
11:15 Electrons & Mitochondria; Real sources of Energy
12:00 Artificial Light versus 280nm-3100nm Light; Big Harma & GLP-1 sidebar
14:16 Autism and Loss of Biological Energy; changes in Light
15:43 Electrons in Biology; Water; Coherent Domains; Semiconductors
17:15 DHA; Electron Efficiency; Cells; Photoreceptors and Converting Energy and Developing Nervous Systems (plural)
19:20 Phylogeny of Oxytocin and DHA sidebar; pi-electons; DHA dictates DNA
22:40 Jack Kruse Quote
23:36 Cells, Tissues, & Synapses; Origins of Autism; DHA roles
26:14 Autism and X, Y, Z comorbid conditions (plural); definitions of Autism (modern versus origins), Criteria
29:23 DHA takeaways; efficiency
31:41 NF-kB; creating the womb and nervous systems; Autism and Orbitofrontal Cortex (OFC)
35:06 Reviews/Rating & Contact Info
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These are comments about my opinion and experience with education- the classroom and the school day. There are many contrasts to the Autistic phenotype when it comes to the classroom and school day.
Autism and Education https://youtu.be/zQpNtvS-tWw
B.3 https://youtu.be/Ov_Bw--zzrQ
Kanner Kids https://youtu.be/FjELhG5FKzs
Asperger's Autistic Intelligence https://youtu.be/qygNL6wCrhg
X: https://x.com/rps47586
Hopp: https://www.hopp.bio/fromthespectrum
email: [email protected]
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For today’s episode, Dr. Hanna Stevens joins me to discuss early prenatal factors of early brain development. Dr. Stevens received an MD and PhD in Neuroscience from the University of Illinois. Dr. Hanna Stevens leads the Psychiatry and Early Neurobiological Development Lab at the University of Iowa Carver College of Medicine. Dr. Stevens is a distinguished Professor of Psychiatry and holder of the Ida P. Haller Chair.
Her work leads groundbreaking research into the molecular and cellular foundations of early brain development, and is pivotal in linking prenatal stress, environmental factors, and genetic influences on childhood behavior and the emergence of disorders. With a focus on the critical periods of pregnancy and early childhood, her research aims to revolutionize the diagnosis and treatment of conditions throughout the lifespan. By the end of this episode, we hope you receive valuable information about the Placenta, Womb, and Development.
Dr. Hanna Stevens https://medicine.uiowa.edu/psychiatry/profile/hanna-stevens
Iowa Healthcare https://uihc.org/childrens/providers/hanna-e-stevens
Psychiatry and Early Neurobiological Development Lab (PENDL) https://stevens.lab.uiowa.edu
Publications https://stevens.lab.uiowa.edu/publications
0:00 Dr. Hanna Stevens
2:00 Journey into Neuroscience and Psychiatry
8:13 Prenatal Development of Autism
14:02 The significance of NF-kB in Brain Development
23:10 Serotonin; Leukocytes as a window into our Biology; Cortisol
29:02 Steroid Hormones and Stress & Development
34:12 Methylation
40:00 Cell Proliferation & Migration in Fetal Development; Antioxidants
45:56 Oxidative Stress; Mitochondria; Antioxidants
48:30 Quantum Biology/Physics
** Me shaking my head at minute 48:50 is not intended at Dr. Stevens, but at myself because I tell myself not to keep going to the electrons and light for a Cause of Autism to guests
53:19 Future Research & Dorsal Striatum; Volume; Brain Development
1:00 Reviews/Rating; Contact Info
X: https://x.com/rps47586
Hopp: https://www.hopp.bio/fromthespectrum
email: [email protected]
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For today's episode, we go back to the origins of Autism. It seems necessary because of the recent shifts in what is Autism and the confusion in the rates of Autism. Autism was here in the 1930's, and it magically showed up in different areas of the world. The two-part series intends to remember the phenotypes that appeared and became known as Autism and Asperger's.
It is my opinion, the recent shifts in defining Autism could be rooted in questionable intentions. Regardless, one goal of the podcast is understanding and explaining Autism. By the end of the episode, and by the end of the two-part series, I hope you gain understanding of the Autistic Phenotype.
If the children described by Asperger in Autistic Psychopathy in Childhood were alive today, they would receive a smorgasbord of diagnosis.
Introduction to the Podcast (00:00:00 - 00:00:41,320):
Asperger's Work and Concept of Autism (00:00:41,320 - 00:02:21,040):
Historical Context and Asperger vs. Kanner (00:02:21,040 - 00:05:10,520):
Case Study: Fritz V. (00:05:45,080 - 00:11:25,920):
Detailed case study of Fritz, highlighting social integration issues, motor delays, superior speech, and behavioral challenges.Discussion on how modern medicine might label Fritz with multiple diagnoses.Case Study: Harold L. (00:13:21,040 - 00:15:25,240):
Description of Harold's struggles with school, social withdrawal, and the conflict between autistic capabilities and societal expectations.Case Study: Ernest (00:17:37,960 - 00:21:00,160):
Ernest's case with normal development but severe academic struggles, social withdrawal, and unique learning styles, suggesting individual teaching methods for autistics.Case Study: Hellmuth L. (00:21:16,680 - 00:24:40,240):
Helmuth's case with complications at birth, delayed development, obesity, and later sexual tendencies, linking these to environmental and light exposure changes.Common Features Across Asperger's Cases (00:24:49,600 - 00:26:29,720):
Summary of common traits observed across Asperger's 200 cases, including eye gaze issues, peripheral vision, and social interaction patterns.Asperger's Insights on Autistic Intelligence (00:26:29,720 - 00:27:37,760):
Discussion on the unique intelligence and original ideas in autistic children, introducing the concept of "Asperger's little professors."Reflection on Autism as a Phenotype vs. Disorder (00:27:37,760 - 00:29:12,680):
Historical Figures and Autism (00:29:12,680 - 00:29:41,480):
Speculation on whether historical geniuses might have had autistic traits, highlighting that autism could be viewed as a superpower in certain contexts.Conclusion (00:29:41,480 - 00:30:42,800):
X: https://x.com/rps47586
Hopp: https://www.hopp.bio/fromthespectrum
email: [email protected]
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For today's episode, we go back to the origins of Autism. It seems necessary because of the recent shifts in what is Autism and the confusion in the rates of Autism. Autism was here in the 1930's, and it magically showed up in different areas of the world. (Part 2 on Asperger's "little professors" next). The two-part series intends to remember the phenotypes that appeared and became known as Autism.
It is my opinion, the recent shifts in defining Autism could be rooted in questionable intentions. Regardless, one goal of the podcast is understanding and explaining Autism. By the end of the episode, and by the end of the two-part series, I hope you gain understanding of the Autistic Phenotype.
Leo Kanner: Autistic Disturbances of Affective Contact http://www.autismtruths.org/pdf/Autistic%20Disturbances%20of%20Affective%20Contact%20-%20Leo%20Kanner.pdf
0:00 Intro
0:45 Erwin Schrödinger Quote; Quantum Physics; Missing link in Medicine
2:56 Kanner's Autistic Disturbances of Affective Contact; Demographics
3:52 Ages; Boys versus Girls; Phenotypes; Family History
6:26 Important consideration of Family History- electricity and nnEMF; general observation and important phenotypes
9:30 Anticipatory Motor Adjustment; Reflexes; Sensory and Adaptive Responses
13:32 Monotonous Repetitions; Sameness
15:26 Spelling and Language
18:20 Commands and Intrusions
18:57 Autism, not Autism and ADHD; Intense Fixations & Neuroplasticity; Default Mode Network; Sameness
24:00 Oblivious to Others; Inattentive- It's not ADHD, it's Autism
27:39 Changes & More on Sameness & Repetitions
30:10 Rote Memory; Gastrointestinal: Timelines and Milestones
X: https://x.com/rps47586
Hopp: https://www.hopp.bio/fromthespectrum
email: [email protected]
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For today's episode, Dr. Eric Weiss, MD, explains an exciting medical approach for Autism. Dr. Weiss, who holds board certification in Plastic and Reconstructive Surgery, is a notable figure in regenerative medicine. Dr. Weiss is a Veteran of the U.S. Navy. Dr. Weiss attended Duke University Medical School for his medical degree, completed his General Surgery Residency at the University of California, San Francisco (UCSF), and did his Plastic Surgery Residency at the University of Miami. He has a special interest in using regenerative therapies to address autism.
Dr. Eric Weiss recounts his journey into innovative medical practices, moving away from conventional pharmaceutical treatments. As a father to Marston, his dedication to exploring treatments for autism stems from personal experience. Throughout his story, his enthusiasm for natural healing methods is evident. By the end of this episode, listeners should gain insight into a thoroughly researched medical intervention that's gaining traction in the autism community.
Dr. Eric Weiss, MD: https://northfloridastemcells.com
Dr. Eric Weiss, MD: https://linktr.ee/neflps
Educating Marston: https://www.educatingmarston.com
Disclaimer: This is not Medical Advice.
0:00 Dr. Eric Weiss, MD
1:55 Dr. Weiss's Medical Journey
5:01 Intersection of Autism and Stem Cell Research
12:09 Personal Experience as a Parent with Autism
15:58 Understanding Umbilical Cord Blood Treatment
22:39 The Process of Umbilical Cord Blood Donation
25:55 The Science behind Stem Cell Healing
32:31 Future of Regenerative Medicine
34:24 Natural Healing and Lifestyle, Not Big Pharma
36:56 Mitochondrial Function & Energy Production
39:09 The Impact of Light on Health
41:07 Understanding Inflammation & Modern Disease
44:30 Stem Cell Therapy: Mechanisms & Effects
48:41 The Future of Medicine: Beyond Pharmaceuticals
54:14 Professional Transition into Stem Cell and Regenerative Therapy
58:05 Exploring Cytokines & Interleukins; Patterns of Disease; Dr. Weiss's Contact Info
1:07 Reviews/Ratings; Contact Info
X: https://x.com/rps47586
Hopp: https://www.hopp.bio/fromthespectrum
email: [email protected]
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For today's episode, Nicole Rincon, PA-C, returns to discuss the risks associated with Autism development. The conversation spans from before conception through to after birth. We'll explore how factors related to the mother can influence autism risk, and we'll look at specific tests and signs in the body (labs and biomarkers) that have been linked to Autism. Additionally, we'll cover environmental influences, dietary considerations, acute medical conditions and medications, seasonal patterns, and various other aspects to be mindful of.
By the end of the episode, we hope you'll gain valuable insights to consider as you navigate pregnancy. Our goal is to educate listeners, especially those who are pregnant or planning to conceive, about these potential risk factors, equipping them with the knowledge to make informed decisions or to be more aware during these pivotal times.
Nicole Rincon https://www.nicolerincon.com/nicole-rincon
Rossignol Medical Center https://rossignolmedicalcenter.com/doctors/nicole-rincon/
TACA Info: https://tacanow.org/wp-content/uploads/2019/10/F-H-2-Nicole-Rincon-Beginning-Biomed.pdf
TACA Talks: https://www.nicolerincon.com/videos
X: https://x.com/NicoleRinconPA
Publications https://rossignolmedicalcenter.com/articles-publications/#published-2024-2-articles
Other Resources:
Autism and the Embryo, and expanding Artificial Light as a possible cause of Autism
https://www.youtube.com/watch?v=NOVp4mIroug
(See 18:36)
https://www.youtube.com/watch?v=OtA-aMN7ziY
DISCLAIMER: THIS IS NOT MEDICAL ADVICE.
0:00 Nicole Rincon
1:00 Understanding Pre-Pregnancy Risks
4:02 Maternal Risks Factors for Autism
6:53 Environmental Factors for Autism
9:56 Alternatives to Common Medications
12:58 The Role of Light & Seasonal Factors
16:02 Serotonin & Autism
18:56 Inflammation & Mitochondria
22:08 Infections & Antibiotics
25:08 Lab Work & Biomarkers for Maternal Health
27:46 Tyrosine, Thyroid, & Iodine; Depression, Fatigue
31:07 Folate & Methylation in Pregnancy; Autoimmune; Pregnancy Complications
40:40 Amino Acids; Dietary Types & Autism; Personal Diets
49:00 Eating Seasonally & Locally
51:01 Post-Pregnancy Nutrition
54:00 Breastfeeding versus Formula Feeding; Environmental Factors & Toxins, Plastics, Water
1:00 The Role of Sunlight on Human Biology; Leptin & Hormones, Metabolism Accountant; Red Light
1:02 Sun and Sunscreen; Beta-Endorphins, Cannabinoids, Hormones
1:07 Concluding Thoughts on Health & Family
X: https://x.com/rps47586
Hopp: https://www.hopp.bio/fromthespectrum
email: [email protected]
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Relationships are challenging.
In this episode, we explore some of the Autistic phenotype challenges in relationships. We discuss symptoms from criteria A are external and criteria B are internal, and how criteria B complicates the symptoms in criteria A. In addition, Autism is a comparison to social-norms, and this is a problem. Some environments/relationships discussed include peer-to-peer, romantic, and parent-child. To begin, we explain the mechanisms behind the speaker-receiver and the use of conveying speech in socialness.
Before we begin, we cover a brief explanation of Speaker-Receiver and human communication.
Dr. Theresa Regan episode https://youtu.be/aUhIreFd5sw
Autism and Adaptive Responses https://podcasts.apple.com/us/podcast/from-the-spectrum-finding-superpowers-with-autism/id1737499562?i=1000658438095
What is Autism: Criteria A https://podcasts.apple.com/us/podcast/from-the-spectrum-finding-superpowers-with-autism/id1737499562?i=1000651048705
The Roles of Oxytocin and Vasopressin in the Autistic Phenotype https://podcasts.apple.com/us/podcast/from-the-spectrum-finding-superpowers-with-autism/id1737499562?i=1000660031273
(0:00) Intro; Speaker-Receiver explanation when conveying speech
(3:55) Unpredicableness in socialness; black and white thinking and context-dependent and adaptive responses; Metabolic energy/resources; Oxytocin and Serotonin
(7:10) Biology that gives us Autism gives us complications to socialness and relationships; Sex-differences and socialness
(8:40) Criteria A is external, Criteria B is internal; Sensory-Processing
(10:32) B.2 and B.3 implicates socialness
(16:58) Direct social interactions
(22:26) Autism versus social norms; Romantic relationships
(26:51) Do Autistics outgrow Autism?
(28:04) Parenting
(31:30) Cohabitating
(32:28) Wrap Up
(32:45) Reviews/Ratings and contact info
Links: hopp.bio/fromthespectrum
X: https://twitter.com/rps47586
Email: [email protected]
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For today's episode, we speak with Dr. Theresa Regan, PhD & CAS, about adolescents and adults with Autism. Dr. Regan is a neuropsychologist with over 25 years of experience serving adolescents, adults, and seniors in hospital settings. She is a Certified Autism Specialist and the Director of the OSF HealthCare Adult Diagnostic Autism Clinic. Dr. Regan has conducted over 1,000 assessments on adolescents and adults with Autism. Her expertise in brain-behavior relationships, adult and geriatric medical conditions, and autism has provided her with a unique set of qualifications for serving adults with autism.
In addition to her clinical work, Dr. Regan is the author of Understanding Autism and the host of the podcast "Autism in the Adult." During the episode, Dr. Regan shares valuable tools and protocols for Autistics as we learn to navigate various responsibilities such as employment and relationships. Her role as a neuropsychologist offers her insights into alternative approaches beneficial for both Autistics and their friends, family, as well as in employment and educational settings.
Dr. Theresa Regan https://www.adultandgeriatricautism.com
OSF Healthcare https://www2.osfhealthcare.org/providers/theresa-regan-1602000
Autism in the Adult https://open.spotify.com/show/2POoTBvzgPr0yIkU7dmw2m?si=31381356153f4903&nd=1&dlsi=8f401dc6fce54bb5
Understanding Autism https://www.amazon.com/dp/B098KQKZT7?binding=kindle_edition&ref_=ast_author_bsi
0:00 Dr. Theresa Regan
1:42 Journey into Psychology and Autism
7:20 Understanding Autism in Adults
13:39 The Role of Self-Knowledge in Relationships
19:47 Challenges faced by Adults with Autism
25:32 Tools and Protocols for Regulation
31:48 Navigating Employment
37:54 The Importance of Self-Care and Balance
43:35 Resources and Future Direction
55:18 Reviews/Rating and Contact Info
X: https://x.com/rps47586
Hopp: https://www.hopp.bio/fromthespectrum
email: [email protected]
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In this episode, we discuss Autism with Nicole Rincon, PA-C from Rossignol Medical Center. Nicole Rincon is a board-certified Physician Assistant (PA-C) who specializes in Pediatric Special Needs, MAPS (Medical Academy of Pediatric Special Needs), Integrative, and Functional Medicine. At Rossignol Medical Center, she is actively involved in patient care, research, and educational content. Nicole adopts valuable holistic and patient-centered care approaches in her practice.
Nicole also brings a deeply personal perspective to the discussion as a mother of children with regressive Autism. This personal journey has fueled her motivation to explore the complexities of Autism, leading her to Rossignol Medical Center. Prior to this, Nicole spent years in medical weight management, focusing on nutritional counseling and wellness supplementation. This background provides her with unique insights into the metabolic, gastrointestinal, and environmental factors influencing Autism.
Disclaimer: This is not Medical Advice
Nicole Rincon https://www.nicolerincon.com/nicole-rincon
Rossignol Medical Center https://rossignolmedicalcenter.com/doctors/nicole-rincon/
TACA Info: https://tacanow.org/wp-content/uploads/2019/10/F-H-2-Nicole-Rincon-Beginning-Biomed.pdf
TACA Talks: https://www.nicolerincon.com/videos
X: https://x.com/NicoleRinconPA
Publications https://rossignolmedicalcenter.com/articles-publications/#published-2024-2-articles
0:00 Nicole Rincon
2:07 Nicole's Personal and Professional Journey into Medicine and Autism; "Who's the guy in Charge?"
12:30 Understanding Autism Trough Research and Interventions; Regression; Omegas and Toxins
21:56 Functional Medicine Approach to Autism; Rossignol Medical Center
25:07 Introduction to various Folate factors, Folate Receptor Antibodies, and Methylation
30:36 The Role of Mitochondrial Dysfunction and the many Comorbid Conditions of Autism (Autism and X, Y, Z)
36:02 Collaborative Approach at Rossignol Medical Center; Research Insights and Opportunities from Nicole's multiple roles
42:22 Challenges with the Current Medical Paradigm
44:09 Maternal Health and its Impact on Autism
48:34 Investigating Autism Beyond Vaccines
50:59 The Role of Light and Environment in Human Biology; Electrons and Magnetism
53:26 Introduction to Nicole's Comprehensive Evaluation from a Functional Medicine Approach; Understanding the Patient and Upstream Dysfunctions
1:02 Multifactorial Approach
1:05 The Future of Medicine, integrating Functional and Patient Center Care
1:13 Reviews/Ratings and Contact Info
X: https://x.com/rps47586
Hopp: https://www.hopp.bio/fromthespectrum
email: [email protected]
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For today’s episode, we discuss Autism with J.D. Barker. J.D. is a New York Times and International Best-Selling Author. His debut novel, Forsaken, caught the attention of legendary Author, Stephen King, who allowed Barker to use one of his characters from Needful Things for Barker’s debut novel. His writing career took off with The Fourth Monkey, which drew widespread attention, leading to a series of auctions and pre-empts for its publishing rights globally. Barker's style often involves intricate plots that blend psychological depth with supernatural or crime elements, appealing to fans of both horror and thriller genres.
Barker's work expanded when he was approached by Bram Stoker's family to co-author a prequel to Dracula, titled Dracul, utilizing previously unpublished notes by Stoker. Barker is a frequent co-author with legendary writer, James Patterson. Listen to how Barker can create such vivid imagination with the characters he creates. In addition, Barker shares critical information on how he navigates such a prolific and successful writing career, often managing many projects with great efficiency. This episode provides critical insights on how the Autistic Phenotype can strive with their unique superpowers.
J.D. Barker https://jdbarker.com/books/heavy-are-the-stones/
J.D Barker and Christine Daigle's upcoming book in November, Heavy Are the Stones https://www.amazon.com/Heavy-Are-Stones-J-D-Barker-ebook/dp/B0D5RKLYPC/ref=sr_1_1?crid=2TRLN3LUMCEFA&dib=eyJ2IjoiMSJ9.FJj1OgrpA4iJyLa9pHJ9ZQ.GiVjyydPJtKVpMdmN0HupggAyTd0GcjUBJ9l5UUA6xM&dib_tag=se&keywords=heavy+are+the+stones+jd+barker&qid=1728672013&sprefix=jd+barker+heavy%2Caps%2C119&sr=8-1
J.D. Barker Books https://www.amazon.com/s?k=JD+Barker&crid=18DBO8RHA8T05&sprefix=jd+barker%2Caps%2C111&ref=nb_sb_noss_1
X: https://x.com/jdbarker
0:00 JD Barker
2:49 Early Years of Creativity, Books, & Understanding Autism; Trying to Fit-In; Following Rules, Black and White thinking versus Gray
11:43 Superpowers of Writing as a Reflection, Creativity, & Intelligence of the Inner World
15:00 Superpowers of Autism by Creating Catalogs: Patterns, Visual & Thinking in Pictures, & Creating Characters
20:42 Balancing Life with Autism
23:51 The Writing Bout; the Importance of Managing Energy to avoid Burnout
35:42 Focusing on the Process, not the Outcome
39:35 Stephen King's Blessing & Approval of Forsaken; the journey to meet King
41:44 James Patterson Collaborations
43:25 Bram Stoker & the Prequel to Dracula, Dracul; Superpower of the Autistic Brain example
46:11 Recognizing Autism in Children
49:11 Future work
52:42 Review/Ratings & Contact Info
X: https://x.com/rps47586
Hopp: https://www.hopp.bio/fromthespectrum
email: [email protected]
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In this episode, we discuss Autism and the Default Mode Network. According to Lisa Feldman-Barrett, the Default Mode Network has many names because it has been discovered, named, rediscovered, and renamed many times. I do not disagree with the Science regarding Autism and the Default Mode Network. However, I disagree with the Interpretation of the Data. This IS our Default; our preferred state; the core of the Autistic Phenotype.
After listening to this episode and understanding B.3, you can understand MOST of Autism. The only reason you cannot understand ALL of Autism from these two episodes is the amount of Phenotypes branching off of B.3 and our Default Mode. Autism IS preference for ALONENESS and SAMENESS. This minimizes sensations and distractions that interfere with our internal world. This state is NOT abnormal, how society interferes with it makes it abnormal.
If you want more Autistics to ACHIEVE, then understand your interaction, interference, and interpretation of what YOU think Autism is, and that delta determines how much we are prevented in life. This, of course, becomes slightly different the more profound the Autistic Phenotype is with that specific person.
In this episode, we will explore the different brain regions and the goals of these regions as it relates to our phenotypes. We will get into some "Thinking in Picture" and thinking styles. This will be a good time because of a future guest on From the Spectrum Podcast discussing Autism and Creativity. This is exciting for me.
Lisa Feldman-Barrett Core System (DMN) https://lisafeldmanbarrett.com/2017/02/05/core-systems/
0:41 Research at UT-Austin and the Importance of the INFRARED LIGHT study with Autism
5:48 Autism and the Default Mode Network (DMN); Buzzword in Science
7:19 Humans and our Prediction Machine and Sensory Processing; Innate or Learned; Oxytocin in the Autistic Phenotype;
9:36 History of DMN (from Lisa Feldman-Barrett) and the many names; Core Systems
11:58 medial Prefrontal Cortex (covered in many episodes); roles, E/I, connectivity, Internal Calculators
14:45 Posterior Cingulate Cortex (PCC); Self-Referential Thinking, Memory, Attention, Task-Switching and the harms of calling it ADHD
18:03 Angular Gyrus; Language, Sensory Processing "Bee Movie" example, Mental Images, Narratives, Empathy
21:12 Supplementing Relationships
23:36 Sensation-Perception
24:30 Precuneus; Self-Awareness, Episodic Memory, Prediction and Strategic Planning
25:52 Social Cognition; Social Cues and Skills
27:50 Autism and Anxiety- Avoidance, Breathing (Physiology), and Valence (how we feel)
28:48 Internal Calculators; Metabolic Bank Account and Demands
29:26 the DMN is a Misnomer and the Default (tendency, phenotype) of the Autistic
33:04 Reviews/Ratings, Contact Info
X: https://twitter.com/rps47586
Hopp: https://www.hopp.bio/fromthespectrum
email: [email protected]
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For today's episode, we discuss Autism with Dr. Yehezkel Ben-Ari. Dr. Ben-Ari is a pioneer in the field of human development with over five decades of academic and private research. He has over 520 publications with a strong passion for early detection and treatment of brain disorders. His work includes studying Human Development, Autism, Epilepsy, Parkinson's, and Brain Tumors. He is a leader in how science understands the roles GABA and Chloride during early development and the NCCK1 importer and KCC2 exporter during the Excitation/Inhibition shift.
In 1986, he led INSERM Neurobiology and Pathophysiology of Development before shifting to Start-Up private investigation in 2008. He is the founder of Neurocholre, B & A Biomedical, B & A Oncomedical, INMED, and IBEN. Recently, Dr. Ben-Ari has made wonderful contributions towards Autism identification in the Placenta using the work of "Neuroarchaeology" and Machine Learning. Dr. Ben-Ari is the recipient of many awards including Grand Prix de l'INSERM, Grand Prix European Society of Epilepsy, and Grand Prix Gagne Van Heck Belgian National Scientific Research (FNRS), to name a few. His book, The First 1000 Days, will soon have an English version. Treating Autism with Bumetanide is available now.
Dr. Yehezkel Ben-Ari https://www.inmed.fr/en/evenement/en-yehezkel-ben-ari
Neurochlore https://www.neurochlore.fr/en/
Machine Learning https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994821/
Excitatory Actions of GABA https://www.nature.com/articles/nrn920
GABA https://journals.physiology.org/doi/full/10.1152/physrev.00017.2006
Neuro-Archaeology https://pubmed.ncbi.nlm.nih.gov/18951639/e
Books: https://www.amazon.com/s?k=yehezkel+ben-ari&crid=1LZK6JWEBG4NC&sprefix=yehezkel+ben-ari%2Caps%2C196&ref=nb_sb_noss
0:00 Dr. Yehezkel Ben-Ari
3:08 Understanding Autism: Origins and Early Detection
8:08 The Roles of Machine Learning Data Analysis in Identification
14:56 The Impact of Environment and Autism
23:18 Treatment Approaches and Efficacy, Bumetanide, and NKKC1 Inhibitors
31:04 Challenges in Autism Research, including the Genetic Debate, Medical Paradigms, and Decision-Makers
38:00 Future Direction and Innovative Research, Autism in the Placenta and the Environment during Pregnancy
53:56 Wrap Up / Reviews and Ratings, Contact Info
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Hopp: https://www.hopp.bio/fromthespectrum
email: [email protected]
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For today, just a brief introduction to research beginning at UT-Austin, University of Texas at Austin, led by Dr. Francisco Gonzalez-Lima. The study is called: Effects of Transcranial Infrared Light Stimulation on Symptoms of Autism Spectrum Disorder. In the link below, it is Study #2.
Dr. Francisco Gonzalez-Lima https://dellmed.utexas.edu/directory/francisco-gonzalez-lima
Research Link (Study #2) https://labs.la.utexas.edu/gonzalez-lima/participate-in-our-research/
Research Team https://labs.la.utexas.edu/gonzalez-lima/team/
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Hopp: https://www.hopp.bio/fromthespectrum
email: [email protected]
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In this episode, we discuss eye-tracking as an early biomarker for Autism. Eye-tracking, on infants, improve assessment outcomes at young ages, as young as 14-months-old. Adding biomarkers to the assessment process is valuable, and Autism research is beginning to offer more biomarkers. We've covered biomarkers in cellular respiration, serotonin, two studies on 6-week-olds- 1) predicted profound Autism with brain cortical organoids and 2) salience network connectivity. Today, we review four scientific papers on eye-tracking being added to the assessment process.
A valuable consideration is the roles our eyes have on brain development, which we cover as well.
Pierce et al 2019 https://pubmed.ncbi.nlm.nih.gov/31034004/
Wen et al 2022 https://www.nature.com/articles/s41598-022-08102-6
Keehn et al 2024 https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2818669
Early Autism Evaluation (EAE) https://medicine.iu.edu/expertise/indiana-health/access-to-care/autism/care
Rudling et al 2024 https://journals.sagepub.com/doi/full/10.1177/13623613231203037
The Roles of Oxytocin and Vasopressin in the Autistic Phenotype https://www.youtube.com/watch?v=DAtmC-s1_e0
0:00 Intro; 2 studies on 6-week-olds; Eye Development and Brain Development, Opsins
5:23 OCT (Optical Coherence Tomography) scans and Brain predictors, Melanopsin and Choroid Plexus
7:06 Melanin and Melanopsin through the body and biochemistry
8:39 Fruit Tree Example from Dr. Kruse
9:29 Eye-tracking and Autism as a Biomarker; Neuroplasticity- Human's capacity to think; Autism is NEW in human evolution
14:05 Social Attention; Oxytocin- magnocellular and parvocellular; Objects over People; Gaze Following
17:21 Gaze Attention
18:02 Joint Attention
19:12 Studies on Infants; Pierce et al, 2019
25:00 Wen et al, 2022
27:03 Keehn et al, 2024 and Early Autism Evaluations (EAE)
29:25 Rudling et al, 2024
32:15 Wrap-Up/Final Thoughts
34:55 Reviews/Ratings, Contact Info
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Hopp: https://www.hopp.bio/fromthespectrum
email: [email protected]
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For this episode, we discuss the roles and sensitivity of mitochondria with Dr. Richard Frye, MD, PhD. Dr. Frye received an MD and a PhD in Physiology and Biophysics from Georgetown University. He is board certified in Pediatrics, Neurology with special competence in Child Neurology, and as a Certified Principal Investigator. In addition, he has a Masters in Biomedical Sciences and Biostatistics from Drexel University. Dr. Frye has over 300 publications in leading journals and book chapters.
He currently sees patients as a Neurologists and Director of Research at Rossingnol Medical Center and at Neurodevelopmental Precision Medicine. In 2022, Dr. Frye co-founded the Autism Discovery and Treatment Foundation where they are dedicated to discover biomarkers, metabolic endophenotypes, and treatments for neurodevelopemental disorders.
Dr. Frye shares many figures during the conversation so the listener can follow along.
Dr, Richard Frye https://drfryemdphd.com
CV https://wparticles.seek2understand.org/wp-content/uploads/2023/02/DrFryeCVJan2023.pdf
Rossingnol Medical Center Facebook https://www.facebook.com/RossignolMedicalCenter
Neurobiology of Disease 2024 paper https://www.sciencedirect.com/science/article/pii/S0969996124001190?via%3Dihub
Autism and GI, and exploring how changes in Light have major implications (Apple) https://podcasts.apple.com/us/podcast/from-the-spectrum-finding-superpowers-with-autism/id1737499562?i=1000664349495
0:00 Dr. Richard Frye
6:13 Intro into mitochondria & energy production, various disease & dysfunction
11:16 Mitochondrial DNA, sensitivity, and the roles with epigenetics
16:16 Biomarkers of mitochondrial dysfunction, delicate delivery (space and time) into the electron transport chain
20:58 Cytochrome C Oxidase (complex IV); Carnitine, Fat, and Creatine
26:57 Molecules connected to aging & cellular respiration, environemental signals implicating mitochondria
30:26 Terrible Trio: oxidative stress, mitochondria dysfunction, immune/inflammation, DAMPS & inflammation
34:29 Environmental risks for the Embryo, overreactivity of mitochondria (200%) and physiological insults and regression
42:50 Tryptophan (aromatic amino acid), NAD, and Gastrointestinal biosynthesis
45:52 Light as an environmental change factoring into the Autistic Phenotype, Infant Tree and Adult Tree examples; Vitamin D (skin & brain are connected through Neuroectoderm)
54:54 Future Research
59:58 Wrap up, Reviews/Ratings
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Hopp: https://www.hopp.bio/fromthespectrum
email: [email protected]
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In this episode, we discuss the mitochondria. You know mitochondria as the "powerhouse" of the cell, but this biological process is biophysics meeting biochemistry. We discuss glycolysis, the TCA cycle (or Citric Acid cycle or Krebs cycle), and Oxidative Phosphorylation. This discussion goes deep inside the atomic molecular level with electrons and protons. Hang in there with the discussion and topic of Autism and understanding of the generational link to a loss of electrons.
Jack Kruse https://www.patreon.com/DrJackKruse/posts
Glycolysis https://www.ncbi.nlm.nih.gov/books/NBK470170/#:~:text=Glycolysis%20is%20a%20central%20metabolic,use%20in%20other%20metabolic%20pathways.
Citric Acid cycle https://en.wikipedia.org/wiki/Citric_acid_cycle
Oxidative Phosphorylation https://en.wikipedia.org/wiki/Oxidative_phosphorylation
0:00 Intro; Light, water, magnetism; The "powerhouse" and understanding of healthy living organisms and different cell types; Photosynthesis and Cell Respiration
4:11 Prokaryotes, Eukaryotes, and Cytochrome C Oxidase (CCO)
6:53 Mitochondria and Cellular Respiration 1) Glycolysis, 2) Citric Acid cycle, and 3) Oxidative Phosphorylation (OXPHOS)
8:25 Glycolysis
10:03 Citric Acid cycle
12:02 OXPHOS
13:51 Cytochrome I
15:07 Cytochrome II
16:08 Cytochrome III
17:10 Cytochrome IV and creating water
19:56 Not all water is equal/same; Aging; Light and Melanin and Rates of Autism
29:20 Cytochrome V and ATPase; Chromophores
33:56 Evolution and losing electrons; Autism and modern health complications
37:50 Environmental signals due DNA sequencing; Autism research and Genetic studies
40:23 Reviews/Ratings and contact info
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Hopp: https://www.hopp.bio/fromthespectrum
email: [email protected]
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In this episode, we challenge the modern trend of Autism and ADHD comorbid diagnosis. We will use children from Kanner and Asperger to show these so-called ADHD symptoms are simply parts of the Autistic Phenotype. However, society finds it easier to lump these two conditions together, and we question why. We review both, the inattentive criteria and the hyperactivity and impulsivity of ADHD and explain when the Autistic phenotype exhibit these conditions.
The criteria for ADHD are downstream behaviors seen across multiple reasons and act as a collect-all. I did not say ADHD does not exist, but I do say Autism and ADHD existing simultaneously seems unlikely if you really understand the phenotypes. Might it just be easier for society to lump these together instead of challenging the differences?
B.3 and Inattention are complete opposites. Hyperactivity and Impulsivity can show up when anyone is in the wrong or horrible environment.
Autism and ADHD https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8918663/
Leo Kanner http://www.autismtruths.org/pdf/Autistic%20Disturbances%20of%20Affective%20Contact%20-%20Leo%20Kanner.pdf
Hans Asperger https://psycnet.apa.org/record/1992-97284-002
0:00 Intro; Brief Note on how environmental signals such as electromagnetic fields (EMF, i.e., Light) informs the genes on how to respond, and how disease manifests
2:51 Autism and ADHD; Neurodiversity; and some problems in society
7:58 Core of Autism- B.3, and Donald Triplett example; B.2 and Social Communication
13:27 Autistic Phenotypes
19:01 ADHD Phenotypes
21:41 Specifiers and Lumping Contrasting Phenotypes
33:18 Medication and ODD (Oppositional Defiant Disorder) Rant
35:42 Autism conundrum with ADHD
38:45 Reviews/Ratings and Contact Info
Hopp: https://www.hopp.bio/fromthespectrum
X: https://twitter.com/rps47586
email: [email protected]
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