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Penis Project is one of our favourite podcasts (and certainly popular with our patients), so we were delighted to welcome Host and Sexologist, Melissa Hadley-Barrett to join us for a chat. What is the Penis Project? Who is it for? (anyone with a penis, anyone who knows someone with a penis, or anyone who would like to have a penis apparently)! A cracking chat and we highly recommend subscribing. Just search Penis Project or browse the links below
Even better on our YouTube channel
Websites:
https://melissahadleybarrett.com Men’s health only
https://rshealth.com.au/ All genders
SPECIAL OFFER - use the code MHB10 at the checkout on all the programs (penile rehab and erectile dysfunction and peyronies) or in the shop to get a 10% discount.
Facebook:
https://m.facebook.com/p/Melissa-Hadley-Barrett-100085237672685/
https://www.facebook.com/profile.php?id=100085146627814
Instagram:
https://www.instagram.com/melissahadleybarrett/
https://www.instagram.com/restorativehealth.clinic/
TikTok: @melissahadleybarrett
YouTube: Melissa Hadley Barrett
Linkedin:
https://www.linkedin.com/in/melissa-hadley-barrett/
TEDX
https://www.youtube.com/watch?v=IjHj1YTmLoA -
The world's longest running live robotic surgery meeting took place in Bordeaux last week and Declan and Renu were there to bring you all the highlights! The 21st Meeting of the EAU Robotic Urology Section (ERUS) was their biggest ever with more than 1000 delegates watching more than 40 live surgeries from the world's top robotic surgeons. And this year includes some quite spectacular telesurgery with surgeons in Bordeaux and patients 8000km away in Beijing!! Renu takes a few new robots for a test drive, and we catch up with some of the biggest names in the business.
This is a Themed Episode supported by our Silver Partners, Device Technologies Australia, distributors of the da Vinci Surgical System across Australia, New Zealand and South-East Asia
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A big day at ESMO in Barcelona today as our friend and colleague A/Professor Arun Azad presents the results of the UpFront PSMA trial for the first time. The data were revealed in the main prostate cancer session at ESMO and simultaneously published in Lancet Oncology. UpFront PSMA is a randomised controlled trial comparing ADT and docetaxel, with ADT + done + LuPSMA in men newly diagnosed high-volume mHSPC. This is a world-first readout of LuPSMA in a prospective randomised trial for mHSPC, and clearly shows a benefit. We dive into the details today with Arun, and another friend and colleague, Professor Michael Hofman, nuc med lead for UpFront PSMA.
This is a Themed Podcast supported by our Silver Partners, Novartis.
Even better on our YouTube channel
Full paper in Lancet Oncology here -
More than 500 salvage radical prostatectomies!!! Yep it would be fair enough to describe Dr Paul Cathcart as being "experienced" in the most challenging scenario we face as prostate cancer surgeons. Surgery for cancer recurrence in the prostate following radiotherapy or various forms of ablative therapy is never easy, and can all too often lead to issues with healing and quality of life recovery due to the impact of prior failed treatments, so we are always keen to see how we can improve outcomes.
Paul dropped into the GU Cast studio when back in Melbourne this week, a little over ten years on from his Fellowship training here. He is a Consultant Urologist at Guy's & St Thomas' NHS Foundation Trust in London, where his main area of expertise is indeed salvage robotic radical prostatectomy. Paul shares his perspectives and tips and tricks for performing this procedure to try and give patients the best possible outcome, and also explains why he prefers the da Vinci Surgical System over the new robot kids on the block.
This is a Themed Podcast supported by our Silver Partners, Device Technologies, distributors of the da Vinci Surgical System.
Even better on our YouTube channel -
Testis cancer! We don't talk enough about this on GU Cast. But we are making up for it today with a cracking overview of three hot topics in testis cancer a couple of world-leading testis cancer experts. We are joined by Rob Hamilton (Urologist, Princess Margaret Cancer Centre, Toronto), and Ben Tran (Medical Oncologist, Peter Mac, Melbourne) to discuss changes in surveillance for stage 1 seminoma, changes in the management of stage 2 seminoma (including robotic RPLND), and miRNA as a really useful biomarker. A really lively discussion on three really topical areas in testis cancers.
Even better on our YouTube channel
We recorded this one at the ANUP Annual Scientific Meeting in July 2024. You can find a full GU Cast covering the rest of the ANZUP24 highlights here -
As if any of us need an excuse to go to beautiful Bali! Well the Urological Association of Asia (UAA) Annual Meeting takes place there from 5-8th September 2024. Renu caught up with Dr Agus Rizal Hamid recently to hear what the UAA have in store for us!
www.uaa2024.com -
How often do you check PSA and testosterone in your patients on androgen deprivation therapy? Probably not often enough!! Declan caught up with friend of the podcast Professor Axel Merseburger at a conference recently to chat about this under-appreciated topic. Don't get too distracted by fancy scans and genomic testing; but do make sure you know a bit about why it matters to get testosterone (and PSA) as low as possible.
This is a Themed Podcast supported by our Gold Partners, Mundipharma.
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Today we dedicate our podcast to the memory of our colleague, Dr Brian Kelly (40), who passed away unexpectedly this week. We are devastated to lose Brian, who was a Consultant Urologist at Peter Mac and Eastern Health here in Melbourne, and one of our closest friends in the world.
Here we replay the Memorial Session which we conducted at Peter Mac this week. It features some great memories of Brian from contributors across the world; all of us shocked to lose one of the most special people in our urological community.
Our heartfelt condolences to Brian's mother Margaret, siblings Finnian, Sean and Ruth, and his son Tadhg.
Vale Brian we will miss you always x
YouTube for full video -
We were very happy to have world-famous kidney cancer guru Dr Rana McKay in Australia this week to do some educational events and to visit us at Peter Mac. So of course we also invited her to the GU Cast studio to pick her brains on all things kidney cancer, along with Dr Lewis Au, GU Medical Oncologist at Peter Mac. We asked them to cover three hot topics:
1. Adjuvant immunotherapy following surgery for kidney cancer
2. First line management of metastatic kidney cancer - how do we choose best options for individual patients?
3. Future-gazing in renal cancer, including a focus on belzutifan.
Even better on our YouTube channel
Rana's visit to Australia was supported by our friends at MSD, Silver Partners of GU Cast.
Links:
Previous GU Cast on Keynote-564
Renu's new paper in Nature Reviews Urology! (mentioned in the intro) -
Renu and Declan escape winter in Melbourne to enjoy a few days of sunshine and science at the #ANZUP24 Annual Scientific Meeting on the Gold Coast. ANZUP is our fantastic GU Oncology co-operative trials group here in Australia and New Zealand and have an outstanding record in running clinical trials and supporting research and education in GU Oncology. Plus this is their 14th Annual Scientific Meeting with some outstanding National and International guests.
We catch up with Paul Nguyen, Elena Castro, Ravi Kanesvaran, Fiona McLean, Cristiane Bergerot and Co-Convenor Matt Roberts to bring you some great highlights of this year's meeting.
GU Cast Conference Highlights are supported by our Gold Partners, Bayer China.
Even better on our YouTube channel
Links:
ANZUP -
To celebrate the Paris 2024 Olympics, we bring you this special Olympics-themed episode of GU Cast - our very own Prostate Cancer Olympics! Yes we We are joined in the GU Cast studio by Dr Elena Castro, GU Medical Oncologist at Hospital 12 de Octubre in Madrid, who happened to be passing through Melbourne. And by our own A/Professor Arun Azad, GU Medical Oncologist at Peter MacCallum Cancer Centre, and one of our GU Cast Clinical Advisors.
We have three events and some great medal contenders, but who will win Gold??!! Tune in for some great discussion and debate, and some surprises and controversies along the way.
This is a Themed Podcast supported by our Gold Partners, Johnson & Johnson Pharmaceuticals.
Even better on our Youtube channel -
In the second of our special episodes focussing on GU Oncology in China, we are delighted to welcome back our GU Cast China Editor. Professor Yao Zhu, who has put together this cracking epsiode focussing on radical prostatectomy in China. We are joined by Professor Ming Liu (Beijing Hospital, Beijing) and Professor Jiahua Pan (Ren Ji Hospital, Shanghai) to discuss everything from current practices of pelvic lymph node dissection up to tantalising details of the new surgical robots which are in clinical use in China.
This is a Themed Podcast as part of our Gold Partnership with Bayer Pharmaceuticals in China. We are very grateful to Bayer China for helping us promote GU Cast in China and supporting these Themed Episodes.
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There are patient advocates and there are patient advocates, and then there is Howard Wolinsky! We chat with the inimitable Howard, medical journalist and very long-time active surveillance patient, about his varied interests in low-risk prostate cancer and prostate cancer diagnostics. He runs a great substack called The Active Surveillor with a regular newsletter which we devour every week! l His current interests are in the abolition of transrectal prostate biopsy and the campaign to re-name grade group 1/Gleason 6 cancer as a non-cancer. We chat about all this and more, including that unforgettable appearance he made at the ASCO GU Plenary session!
Also available on our YouTube channel
Subscribe to the Active Surveillor here -
Part 2 of our Conference Highlight specials from the Advanced Prostate Cancer Consensus Conference, held in April 2024 in Lugano. This is our very favourite prostate cancer meeting and we are thrilled to bring you these highlight podcasts. In this episode we chat with Elena Castro, Nick James, Anthony Joshua, Bertrand Tombal, Silke Gillessen, Aurelius Tomlin, Yüksel Ürün, Gill Morgan, and a gang of nuclear medicine phyicians including Michael Hofman, Louise Emmett, Tom Hope, Stefano Fanti, and Ken Herrmann.
GU Cast Conference Highlights are supported by our friends at Bayer China, Gold Partners of GU Cast.
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Pelvic lymph node dissection down-graded. Systematic prostate biopsies no longer recommended. More clarity around PSMA PET/CT for staging. Surgery no longer recommended for cN1 prostate cancer. Yep the recent updates to the EAU Prostate Cancer Guidelines had a lot of important changes for the global urology community to digest. So we invited EAU Prostate Cancer Guideline Vice-Chair Derya Tilki, and Guideline Board Member Gianluca Giannarini, along with Elio Mazzone to join us for a deep dive into these major changes. All you need to know!
Even better on our YouTube channel -
The first of two Conference Highlight specials from the Advanced Prostate Cancer Consensus Conference, held in April 2024 in Lugano. This is our very favourite prostate cancer meeting and we are thrilled to bring you these highlight podcasts. In this epsiode we chat with Silke Gillessen, Derya Tilki, Jochen Walz, Neha Vapiwala, Dingwei Ye, and the lucky trainees who won a GU Cast Travel Award to attend this year's APCCC.
GU Cast Conference Highlights are supported by our friends at Bayer China, Gold Partners of GU Cast.
Even better on our YouTube channel -
Didn't get to ASCO this year?? Us neither!! But not to worry, we checked in with Dr Marty Schoen who did, and brings us all the key highlights! Marty is a GU Medical Oncologist at the St Louis Veterans Affairs Medical Centre and the University of St Louis, Missouri. He runs through a smattering of stuff that caught his eye at ASCO this year. Thanks Marty!
Also on our YouTube channel -
For Urologists, there are not that many papers that come along where we can say - "this will almost immediately change my practice". But KEYNOTE-564 looks like one of those! A large phase III randomised trial of adjuvant pembro following nephrectomy for renal cell carcinoma in patients deemed at higher risk for recurrence. Regular listeners/viewers might remember we discussed this on GU Cast back in August 2021 when the disease-free survival endpoint was published in NEJM, and it would be fair to say we were cautious and kept saying "we need to wait for the overall survival data". Well here we are! Patients who received pembro for one year had a 38% reduced risk of death. Big news!
We are joined again by Dr Alex Kutikov, Urologist at Fox Chase Cancer Centre, who joined us on the original podcast. We are also joined by his colleague GU Medical Oncologist, Dr Matt Zibelman, who has a lot of experience in this area having been an investigator on the IMmotion 010 study. Unfortunately lead author Dr Toni Choueiri could not join us this time but he gets plenty of mentions!
This is a Themed Podcast supported by our Silver Partners, MSD, manufacturers of pembrolizomab, through an educational grant. MSD had no input into the content of this podcast.
Even better on our YouTube channel
Links:
Full NEJM paper
Previous GU Cast on K-564 -
Should we remove bladder cancers piece-meal by chopping them into little pieces, or should we try and remove en bloc with a margin around the base?? This very nice randomised controlled trial from our friends in Hong Kong demonstrates that the recurrence rate is significantly lower if we use the all-too-rarely used en bloc technique. Dr Jeremy Teoh from the Chinese University Hong Kong joins us to discuss his paper just published in European Urology.
Check out the YouTube version for a video of the technique.
Also available as an audio only podcast wherever you get your podcasts
Full paper here -
Today we have Dr Alicia Morgans, GU Medical Oncologist and Director of Survivorship at Dana Farber Cancer Institute, in the GU Cast studio for a chat. We wanted to ask Alicia to look forward and identify three big challenges we will face in metastatic prostate cancer over the next 5-10 years. What did we come up with??!! Tune in to find out!!
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