Bölümler
-
Join Jame and Callum on this episode about the ultimate 4 rings of power: Tetracyclines. The swiss army knife of antibiotics. We talk through the history, uses, mechanism, PK/PD and resistance.
Become a pharmacophile as you learn something about pharmacophores.
Shows notes for this episode hereSend us a text
Support the show
Questions, comments, suggestions to [email protected] or on X/Threads @IDiots_pod
Prep notes for completed episodes can be found here (Not all episodes have prep notes).
If you are enjoying the podcast please leave a review on your preferred podcast app!
Feel like giving back? Donations of caffeine gratefully received!
https://www.buymeacoffee.com/idiotspod -
Jame and Callum are joined by Lee John and Ella for this episode around the arch-villain of atypical pneumonia and the bogeyman of every spa. Yes Legionella pneumophila (and friends) are addressed in depth whilst this podcast is aerosolised around the world.
Show notes for this episode hereSend us a text
Support the show
Questions, comments, suggestions to [email protected] or on X/Threads @IDiots_pod
Prep notes for completed episodes can be found here (Not all episodes have prep notes).
If you are enjoying the podcast please leave a review on your preferred podcast app!
Feel like giving back? Donations of caffeine gratefully received!
https://www.buymeacoffee.com/idiotspod -
Eksik bölüm mü var?
-
You'll be whooping with knowledge after listening to this one. Come hear all about Bordetella species. From pertussis to kennel cough you'll hear it all.
Show notes for this episode hereSend us a text
Support the show
Questions, comments, suggestions to [email protected] or on X/Threads @IDiots_pod
Prep notes for completed episodes can be found here (Not all episodes have prep notes).
If you are enjoying the podcast please leave a review on your preferred podcast app!
Feel like giving back? Donations of caffeine gratefully received!
https://www.buymeacoffee.com/idiotspod -
The Spring Meeting of the British Infection Assocation is a must for UK infection trainees; In this week's episode Callum summarises for Jame (who was there, but didn't take any notes) the main learning points from the meeting.
Show notes for this episode here
BIA membership is FREE to UK infection trainees, reasonably priced for everyone else, and paid memberships come with online access to the Journal of Infection! Sign up today at https://www.britishinfection.org/join.Send us a text
Support the show
Questions, comments, suggestions to [email protected] or on X/Threads @IDiots_pod
Prep notes for completed episodes can be found here (Not all episodes have prep notes).
If you are enjoying the podcast please leave a review on your preferred podcast app!
Feel like giving back? Donations of caffeine gratefully received!
https://www.buymeacoffee.com/idiotspod -
Jame was there but Callum wasn't! The British Society for Antimicrobial Chemotherapy have several conferences throughout the year, including a Spring meeting with their AGM. But what topics were discussed, I hear you wonder? WELL WONDER NO MORE: Jame'll take you through it!
Notes for this episode hereSend us a text
Support the show
Questions, comments, suggestions to [email protected] or on X/Threads @IDiots_pod
Prep notes for completed episodes can be found here (Not all episodes have prep notes).
If you are enjoying the podcast please leave a review on your preferred podcast app!
Feel like giving back? Donations of caffeine gratefully received!
https://www.buymeacoffee.com/idiotspod -
In this episode, the ID:IOTS Podcast Microbiome Correspondent Dr Anastasia "Tash" Theodosiou, finishes educating Callum and Jame (mostly Callum) on the concept of Microbiotoxicity!
This episode is part 2 of 2. Here we discuss:
- What is microbiotoxicity?
- Risk factors for microbiotoxicity
- Which antibiotics are associated with microbiotoxicity?
- Mitigating microbiotoxicity
https://www.researchgate.net/profile/Anastasia-Theodosiou
https://x.com/doctoranastasiaSend us a text
Support the show
Questions, comments, suggestions to [email protected] or on X/Threads @IDiots_pod
Prep notes for completed episodes can be found here (Not all episodes have prep notes).
If you are enjoying the podcast please leave a review on your preferred podcast app!
Feel like giving back? Donations of caffeine gratefully received!
https://www.buymeacoffee.com/idiotspod -
In this episode, the ID:IOTS Podcast Microbiome Correspondent Dr Anastasia "Tash" Theodosiou, returns to talk about her favourite subject!
This episode is part 1 of 2. Here we discuss:
- What is the microbiome
- Viewing the microbiome as an organ system
- The microbiome's association with disease
- How we study the microbiome
Stay tuned for part 2 (in 1-2 weeks depending on editing), when we talk about the effect of medicine on the microbiome, microbiotoxicity, and what you can do to keep your patients' microbiomes in tip top shape!
https://www.researchgate.net/profile/Anastasia-Theodosiou
https://x.com/doctoranastasiaSend us a text
Support the show
Questions, comments, suggestions to [email protected] or on X/Threads @IDiots_pod
Prep notes for completed episodes can be found here (Not all episodes have prep notes).
If you are enjoying the podcast please leave a review on your preferred podcast app!
Feel like giving back? Donations of caffeine gratefully received!
https://www.buymeacoffee.com/idiotspod -
Join us for this special 80th episode celebrating Jame's favourite trial.
https://www.nejm.org/doi/full/10.1056/NEJMoa1808312
Prep notes (including the images referred to in the poem) here.
Special thanks to the Wikiguidelines Endocarditis crew for their work summarising the evidence this poem was based on.Send us a text
Support the show
Questions, comments, suggestions to [email protected] or on X/Threads @IDiots_pod
Prep notes for completed episodes can be found here (Not all episodes have prep notes).
If you are enjoying the podcast please leave a review on your preferred podcast app!
Feel like giving back? Donations of caffeine gratefully received!
https://www.buymeacoffee.com/idiotspod -
Presenting: More on Penicillin-Binding-Proteins than you realistically ever need to know!
What is the difference between Gram positive and negative bacteria's cell walls?What is a Penicillin Binding Protein (PBP)?Why are they called PBPs?What do PBPs do?What makes MRSA resistant to (most) beta-lactams?These any many more questions answered!
Notion page here - you'll need it for this one, check it out!Send us a Text Message.
Support the Show.
Questions, comments, suggestions to [email protected] or on X/Threads @IDiots_pod
Prep notes for completed episodes can be found here (Not all episodes have prep notes).
If you are enjoying the podcast please leave a review on your preferred podcast app!
Feel like giving back? Donations of caffeine gratefully received!
https://www.buymeacoffee.com/idiotspod -
One PK table to rule them all
One table to find them
One table to bring them all
And in the darkness blind them…
…with awesome antibiotic PK facts you can use to bedazzle your friends and enemies alike!
Prep notes here.Send us a text
Support the show
Questions, comments, suggestions to [email protected] or on X/Threads @IDiots_pod
Prep notes for completed episodes can be found here (Not all episodes have prep notes).
If you are enjoying the podcast please leave a review on your preferred podcast app!
Feel like giving back? Donations of caffeine gratefully received!
https://www.buymeacoffee.com/idiotspod -
The last Pharmacokinetics episode had finally been …Excreted!
This episode covers the ‘drug out’ bit of pharmacokinetics, including things such as:
-What is clearance?
-how to calculate half life
and
-doesn’t everything leave through the kidneys anyway? (That is sort of true, also shut up).
Check out our prep notes (including for this episode) here.Send us a text
Support the show
Questions, comments, suggestions to [email protected] or on X/Threads @IDiots_pod
Prep notes for completed episodes can be found here (Not all episodes have prep notes).
If you are enjoying the podcast please leave a review on your preferred podcast app!
Feel like giving back? Donations of caffeine gratefully received!
https://www.buymeacoffee.com/idiotspod -
It's the second Pharmacokinetics episode you never knew you wanted! Let’s talk about how antibiotics are distributed around the body once absorbed, using the examples of Amoxicillin and CallumShutUpicillin (listen to episode for clarification).
What exactly is the volume of distribution? Want a handy reference for the plasma protein binding of various antimicrobials? Then this is the episode for you! Check out our prep notes (including for this episode) here.Send us a text
Support the show
Questions, comments, suggestions to [email protected] or on X/Threads @IDiots_pod
Prep notes for completed episodes can be found here (Not all episodes have prep notes).
If you are enjoying the podcast please leave a review on your preferred podcast app!
Feel like giving back? Donations of caffeine gratefully received!
https://www.buymeacoffee.com/idiotspod -
It's the Pharmacokinetics episode you never knew you wanted! Callum didn't know either, but never mind that let's talk about how antibiotics are absorbed, and how we can use that to improve our use of them in clinical practice.
Want ammunition for that oral switch? Got someone who's doubting oral antibiotics' effectiveness? Then this is the episode for you! Check out our prep notes (including for this episode) here.Send us a text
Support the show
Questions, comments, suggestions to [email protected] or on X/Threads @IDiots_pod
Prep notes for completed episodes can be found here (Not all episodes have prep notes).
If you are enjoying the podcast please leave a review on your preferred podcast app!
Feel like giving back? Donations of caffeine gratefully received!
https://www.buymeacoffee.com/idiotspod -
In this final episode of the Nobbling the Nonfermentors mini-series, Jame and Callum discuss the (mostly historical) pathogen Burkholderia mallei, causative agent of Glanders.
We did it. We got to the end.
Nonfermentors... Nobbled.Send us a text
Support the show
Questions, comments, suggestions to [email protected] or on X/Threads @IDiots_pod
Prep notes for completed episodes can be found here (Not all episodes have prep notes).
If you are enjoying the podcast please leave a review on your preferred podcast app!
Feel like giving back? Donations of caffeine gratefully received!
https://www.buymeacoffee.com/idiotspod -
Post-publication, Callum and Jame give a little extra information on the SABATO trial in its final form compared to it's pre-publication state.
Final article here:
Efficacy and safety of an early oral switch in low-risk Staphylococcus aureus bloodstream infection (SABATO): an international, open-label, parallel-group, randomised, controlled, non-inferiority trial, Kaasch, Achim J Valiente, Adoración et al. Lancet Infect Dis. 2024 Jan 17:S1473-3099(23)00756-9.
PMID: 38244557.
https://doi.org/10.1016/S1473-3099(23)00756-9Send us a text
Support the show
Questions, comments, suggestions to [email protected] or on X/Threads @IDiots_pod
Prep notes for completed episodes can be found here (Not all episodes have prep notes).
If you are enjoying the podcast please leave a review on your preferred podcast app!
Feel like giving back? Donations of caffeine gratefully received!
https://www.buymeacoffee.com/idiotspod -
JOURNAL CLUB, YO, IT’S A SABATO!!!
Join Jame and Callum as we travel back in time to when we recorded this deep dive into the SABATO trial pre-print, now peer-reviewed and published in the Lancet ID!
In the next episode we'll give a little update as to how the final article differs from the preprint (not much).
We also talked about in our FIS Highlights Episode 3.
We loved this trial and we hope you’ll all give it a read, it’s well worth it!
Article here:
Efficacy and safety of an early oral switch in low-risk Staphylococcus aureus bloodstream infection (SABATO): an international, open-label, parallel-group, randomised, controlled, non-inferiority trial, Kaasch, Achim J Valiente, Adoración et al. Lancet Infect Dis. 2024 Jan 17:S1473-3099(23)00756-9.
PMID: 38244557.
https://doi.org/10.1016/S1473-3099(23)00756-9Send us a text
Support the show
Questions, comments, suggestions to [email protected] or on X/Threads @IDiots_pod
Prep notes for completed episodes can be found here (Not all episodes have prep notes).
If you are enjoying the podcast please leave a review on your preferred podcast app!
Feel like giving back? Donations of caffeine gratefully received!
https://www.buymeacoffee.com/idiotspod -
In this penultimate episode in the Nobbling the Nonfermentors mini-series, Jame and Callum discuss the regionally important neglected tropical disease Melioidosis, caused by Burkholderia pseudomallei.
This episode was based disproportionately on the following article, and we extend our thanks to the authors for thoughfully publishing it so close to us wanting to do a podcast episode on Melioid!
Meumann, E.M., Limmathurotsakul, D., Dunachie, S.J. et al. Burkholderia pseudomallei and melioidosis. Nat Rev Microbiol (2023).
https://www.melioidosis.info/
Link to prep notes here.Send us a text
Support the show
Questions, comments, suggestions to [email protected] or on X/Threads @IDiots_pod
Prep notes for completed episodes can be found here (Not all episodes have prep notes).
If you are enjoying the podcast please leave a review on your preferred podcast app!
Feel like giving back? Donations of caffeine gratefully received!
https://www.buymeacoffee.com/idiotspod -
In this Episode, Callum reflect on his recent runaway success passing the FRCPath Part 2, passes on some tips and tricks for the exam, and then we talk about what 3 antibiotics we would take with us to a Desert Island (that has all pathogens and environments where you would find said pathogens, so not just a desert apparently).
'Prepping to Pass' episodes mentioned: 40, 42, 43 & 50.
The Table and Links mentioned in this episode can be found here: https://idiots.notion.site/70-Reflections-on-Part-2-2023-a193fd830c9b4d6c9381107471fcdbcaSend us a text
Support the show
Questions, comments, suggestions to [email protected] or on X/Threads @IDiots_pod
Prep notes for completed episodes can be found here (Not all episodes have prep notes).
If you are enjoying the podcast please leave a review on your preferred podcast app!
Feel like giving back? Donations of caffeine gratefully received!
https://www.buymeacoffee.com/idiotspod -
How do you think about antibiotics?
This Christmas we give the best gift of all: no puns in an episode.
Join Jame and Callum as they talk about a method for thinking about and explaining antibiotics.
Here are the show notes for this episode: https://idiots.notion.site/69-Choosing-an-antimicrobial-4e7446a91ff6413aa14924a2ba905ffaSend us a text
Support the show
Questions, comments, suggestions to [email protected] or on X/Threads @IDiots_pod
Prep notes for completed episodes can be found here (Not all episodes have prep notes).
If you are enjoying the podcast please leave a review on your preferred podcast app!
Feel like giving back? Donations of caffeine gratefully received!
https://www.buymeacoffee.com/idiotspod -
Did you think the evidence base for Stenotrophomonas was bad? Well allow us to introduce you to Burkholderia cepacia complex!
BCC is pretty niche but a key pathogen in people living with cystic fibrosis. We talk through the (very) limited treatment options and evidence base for this difficult bug.
Prep notes for this episode here: https://idiots.notion.site/68-Burkholderia-cepacia-complex-7bba8a7c74df490cb2e91d087a3cdb2aSend us a text
Support the show
Questions, comments, suggestions to [email protected] or on X/Threads @IDiots_pod
Prep notes for completed episodes can be found here (Not all episodes have prep notes).
If you are enjoying the podcast please leave a review on your preferred podcast app!
Feel like giving back? Donations of caffeine gratefully received!
https://www.buymeacoffee.com/idiotspod - Daha fazla göster