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The December 2024 replay wraps up the year with five previously posted episodes on autoimmune neurology. The episode begins with Drs. Michael R. Wilson and John Pluvinage discussing transcobalamin antibodies. The episode leads into an interview with Dr. Andrew McKeon, who talks about paraneoplastic CAMKV autoimmune encephalitis. In the third episode, Dr. Maarten Titulaer discusses long-term outcomes and rehab in NMDAR encephalitis. The episode continues with Prof. Zsolt Illes discussing the mortality of patients with AQP4 antibody–seropositive neuromyelitis optica spectrum disorder compared with that in the general population. In the final episode, Drs. Marius Ringelstein and Ilya Ayzenberg discuss the effectiveness and safety of Eculizumab in routine clinical care.
Podcast Links:
Transcobalamin receptor Antibodies in Autoimmune Vitamin B12 Central Deficiency
Paraneoplastic CAMKV Autoimmune Encephalitis
Long-Term Outcomes and Rehabilitation in Anti-NMDAR Encephalitis
Mortality in a Danish NMO Cohort
Eculizumab Use in Neuromyelitis Optica Spectrum Disorders
Article Links:
Transcobalamin Receptor Antibodies in Autoimmune Vitamin B12 Central Deficiency
Paraneoplastic Calmodulin Kinase-Like Vesicle-Associated Protein (CAMKV) Autoimmune Encephalitis
Long-Term Cognitive, Functional, and Patient-Reported Outcomes in Patients With Anti-NMDAR Encephalitis
Mortality of the Danish Nationwide AQP4 Antibody-Seropositive Neuromyelitis Optica Spectrum Disorder Patient Cohort
Eculizumab Use in Neuromyelitis Optica Spectrum Disorders: Routine Clinical Care Data From a European Cohort
Disclosures can be found at Neurology.org.
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Dr. Halley Alexander talks with Dr. Vineet Punia about factors influencing the decision to continue or discontinue anti-seizure medications at discharge for patients hospitalized with acute symptomatic seizures.
Read the related article in JAMA.
Disclosures can be found at Neurology.org.
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Dr. Stacey Clardy talks with Dr. Catherine Albin about the key features of educational social media posts, strategies for creating impactful content, the importance of visual appeal, and the role of community engagement in neurology education.
Read the related article in Neurology: Education.
Disclosures can be found at Neurology.org.
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Dr. Justin Abbatemarco talks with Dr. Maarten Titulaer about long-term cognitive and functional outcomes in patients with anti-NMDAR encephalitis and their implications for rehabilitation.
Read the related article in Neurology.
Disclosures can be found at Neurology.org.
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Dr. Stacey Clardy talks with Dr. Elias Sotirchos about the underlying etiologies of myelitis in patients with rheumatologic disease.
Read the related article in Neurology: Neuroimmunology & Neuroinflammation.
Disclosures can be found at Neurology.org.
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Dr. Gregg Day talks with Dr. Kathryn T. Hall about the complexities of the placebo effect, its variability among patients, and the genetic factors that influence responses to placebo treatments.
Disclosures can be found at Neurology.org.
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Dr. Justin Abbatemarco talks with Dr. Ahmad Nehme about the complexities of diagnosing and differentiating between cerebral amyloid angiopathy-related inflammation and biopsy-positive primary angiitis of the central nervous system.
Read the related article in Neurology.
Disclosures can be found at Neurology.org.
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In the concluding segment of this two-part series, Dr. Justin Abbatemarco talks with Dr. Jennifer L. Orthmann-Murphy about genetic leukodystrophies and the increasing recognition of these disorders in adult neurology, the importance of genetic testing, and the evolving treatment landscape.
Read the related articles in Neurology and CHS Perspectives.
Disclosures can be found at Neurology.org.
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In the first part of this two-part series, Dr. Justin Abbatemarco talks with Dr. Jennifer L. Orthmann-Murphy about a practical approach to genetic leukodystrophies, focusing on the importance of genetic testing, identifying red flags in patients, and navigating the complexities of hereditary spastic paraplegia.
Read the related articles in Neurology and CHS Perspectives.
Disclosures can be found at Neurology.org.
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The November 2024 replay features four episodes dedicated to brain health. It kicks off with an interview with Dr. Nicoline Schiess, who discusses the World Health Organization (WHO) Brain Health Unit. Next, Dr. Katrin Seeher delves into the global burden of neurological conditions and the WHO’s strategies to enhance care and awareness. The third segment features Dr. Natalia Rost who introduces and highlights the American Academy of Neurology’s (AAN) groundbreaking brain health initiative. The episode wraps up with Dr. Rost again, who returns to give an update and emphasize the urgency of addressing brain health amidst public health challenges.
Podcast Links:
WHO Brain Health Unit
Global Burden of Neurologic Conditions
Brain Health Initiative with Dr. Natalia Rost
Update on Brain Health with Dr. Natalia Rost
Article Links:
Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
The Brain Health Imperative in the 21st Century—A Call to Action
AAN Brain Health Initiative
Disclosures can be found at Neurology.org.
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Dr. Justin Abbatemarco talks with Drs. Marius Ringelstein and Ilya Ayzenberg about the effectiveness and safety of Eculizumab in routine clinical care.
Read the related article in Neurology.
Disclosures can be found at Neurology.org.
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Dr. Tesha Monteith talks with Drs. Messoud Ashina and Andrea Cipriani about all licensed drug interventions as oral monotherapy for the acute treatment of migraine episodes in adults.
Read the related article in the BMJ.
Disclosures can be found at Neurology.org.
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Dr. Greg Cooper talks with Dr. Clifford R. Jack Jr about objective criteria for diagnosis and staging Alzheimer disease, highlighting recent advancements in biomarkers to bridge the gap between research and clinical practice.
Read the related article in Alzheimer's Association.
Disclosures can be found at Neurology.org.
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Dr. Gordon Smith talks with Dr. Whitley Aamodt about end-of-life care for patients with neurodegenerative diseases, focusing on healthcare utilization, hospice enrollment, and the importance of early conversations about care preferences.
Read the related article in Neurology.
Disclosures can be found at Neurology.org.
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Dr. Kait Nevel talks with Dr. Oumaima Aboubakr about the prevalence of epilepsy in primary CNS lymphoma, to identify factors associated with epilepsy, and to investigate the prognostic significance of seizures in PCNSL.
Read the related article in Neurology®.
Disclosures can be found at Neurology.org.
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In the final part of this three-part series, Dr. Stacey Clardy talks with Drs. Elisabeth Bik and Matthew Schrag about the challenges posed by AI in generating fraudulent research, the importance of cultural solutions to uphold scientific integrity, and the need for modernized data management practices in research.
Read the related article in Undark.
Disclosures can be found at Neurology.org.
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In part two of this special three-part series, Dr. Stacey Clardy talks with Drs. Elisabeth Bik and Matthew Schrag about the processes involved in addressing concerns about research integrity, covering the role of public platforms, using social media for awareness, identifying potential research fraud, and the need for cultural change within the scientific community to prioritize ethical practices.
Read the related article in Undark.
Disclosures can be found at Neurology.org.
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In the first part of this special three-part series, Dr. Stacey Clardy talks with Drs. Elisabeth Bik and Matthew Schrag about critical issues surrounding research integrity and misconduct.
Read the related article in Undark.
Disclosures can be found at Neurology.org.
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Dr. Farrah Mateen talks with Dr. Katrin Seeher about the significant global burden of neurologic conditions, which affects over 3.4 billion people worldwide, and the strategies the WHO is implementing to improve care and awareness.
Read the related article in The Lancet Neurology.
Disclosures can be found at Neurology.org.
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In the October 2024 replay features four episodes on approaches to clinical diagnosis of parkinsonism. The episode starts off with Dr. Colin Hoy discuss the concept of prodromal Parkinson disease and the ethical considerations surrounding its diagnosis. The episode leads into a conversation with Dr. Chris Gibbons discussing skin biopsies to detect phosphorylated α-synuclein. In the third episode Drs. Michiko K. Bruno and Lawrence Golbe about a practical diagnostic algorithm for atypical parkinsonian disorders Drs. Michiko K. Bruno and Lawrence Golbe discuss a practical diagnostic algorithm for atypical parkinsonian disorders. The episode concludes with Dr. Eduardo De Pablo-Fernández talking about the strengths of DAT imaging in diagnosing patients with Parkinsonian disorders.
Previous Podcasts:
The Ethical Landscape of Prodromal Parkinson Disease
Skin Biopsy Detection of Phosphorylated α-Synuclein
General Neurologist's Practical Diagnostic Algorithm for Atypical Parkinsonian Disorders
Interpreting DAT Imaging Results in the Clinical Context
Article Links:
The Ethical Landscape of Prodromal Parkinson Disease
Skin Biopsy Detection of Phosphorylated α-Synuclein in Patients With Synucleinopathies
A General Neurologist's Practical Diagnostic Algorithm for Atypical Parkinsonian Disorders
Neuropathologic Validation and Diagnostic Accuracy of Presynaptic Dopaminergic Imaging in the Diagnosis of Parkinsonism
Disclosures can be found at Neurology.org.
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