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Have you ever wondered what happens inside your body during an allergic reaction?
From itchy eyes to anaphylaxis, the science behind allergies explains why some reactions are mild while others can be life-threatening. In this episode, we break it all down.
Dr. Payel Gupta and Kortney unpack the basics of food allergies, starting with what IgE antibodies are and how they play a role in allergic reactions. They explain what happens when your immune system encounters an allergen, breaking it down with our favorite pinata analogy. This deep dive into the immune system reveals why reactions can range from mild to life-threatening and explores the differences between food allergies, intolerances, and oral allergy syndrome.
If you're newly diagnosed or curious about the science behind allergies, this episode offers valuable insights to help you understand your body and stay safe.
What we cover in our episode about what happens in an allergic reactionWhat is an allergic reaction? Discover how your immune system identifies allergens and triggers a response involving IgE antibodies, mast cells, and histamine. Confused? We use our pinata analogy to simplify it.The role of histamine and inflammation. Learn how histamine is released during an allergic reaction, leading to inflammation and common symptoms.Understanding food allergies vs. food intolerances. Explore the key differences, including symptoms, risks, and why terminology matters.Oral allergy syndrome and environmental allergies. Understand why some allergies don’t lead to anaphylaxis and how cross-reactivity can cause symptoms.Anaphylaxis and severe reactions. Explore why some reactions are life-threatening and how factors like exposure levels and health conditions can influence severity.More resources about allergies:
A Complete Guide to AllergiesMore About Food AllergiesMore About AnaphylaxisFood Allergy Treatment & ManagementLiving with food allergies guideWhat Can You Do If You Can’t Afford Allergen-Free Foods?What if I Can’t Afford My Allergy Medications?This podcast is made in partnership with The Allergy & Asthma Network. Thanks to Genetech for sponsoring today’s episode. While they support the show, all opinions are our own, and sponsorship doesn’t influence our content or editorial decisions. Any mention of brands is for informational purposes and not an endorsement.
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Exploring Neffy Nasal Spray: A Needle-Free Epinephrine Option
Managing anaphylaxis just became easier with Neffy, the FDA-approved nasal spray for epinephrine. This innovative, needle-free option is transforming emergency allergy care.
Dr. Autumn Burnette joins Dr. Payel Gupta and Kortney to discuss how Neffy works, who it’s best suited for, and its potential impact on anaphylaxis treatment. With her expertise in allergy and immunology, Dr. Burnette addresses common concerns about Neffy’s effectiveness, highlights its benefits, and shares practical details like cost, shelf life, and heat sensitivity.
What We Cover in our Episode About Neffy Nasal Spray Delivery SystemA Game-Changer for Anaphylaxis: Discover how Neffy offers a needle-free option for delivering life-saving epinephrine during severe allergic reactions.Patient Benefits of Neffy: Learn how its ease of use and accessibility can make anaphylaxis management less daunting for patients.Addressing Skepticism About Neffy: Dr. Burnette explains how studies validate Neffy’s effectiveness and addresses questions about trusting a nasal spray for emergencies.Practical Tips for Neffy Use: Get insights on cost, insurance coverage, shelf life, and whether Neffy works with nasal congestion or nose jobs!Expanding Treatment Options: Explore why having more options like Neffy is exciting for patients and healthcare providers alike.More resources about Anaphylaxis and Neffy:
Neffy: https://www.neffy.com/Anaphylaxis: https://allergyasthmanetwork.org/anaphylaxis/Epinephrine: https://allergyasthmanetwork.org/anaphylaxis/what-is-epinephrine/Made in partnership with The Allergy & Asthma Network. Thanks to ARS Pharma for sponsoring today’s episode. While they support the show, all opinions are our own, and sponsorship doesn’t influence our content or editorial decisions. Any mention of brands is for informational purposes and not an endorsement.
This podcast is for informational purposes only and does not substitute professional medical advice. Always consult with your healthcare provider for any medical concerns.
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Curious About Neffy, the New Nasal Epinephrine Spray?
We’re diving into everything you need to know about Neffy, the new FDA-approved nasal spray for epinephrine. This groundbreaking, needle-free option provides an easy way to manage anaphylaxis in emergencies.
Dr. Sakina Bajowala joins Dr. Gupta and Kortney to explore Neffy’s unique nasal delivery system, what distinguishes it from traditional auto-injectors, and the science behind its development. With her expertise in allergy and asthma care, Dr. Bajowala walks us through Neffy’s FDA approval journey, the technology that powers the nasal spray, and how it’s changing the landscape of allergy treatment.
What We Cover in Our Episode on Neffy Nasal Spray:Why Neffy Nasal Spray is Unique: Dr. Bajowala explains why nasal epinephrine is an innovative choice for anaphylaxis treatment and when it may be preferable to injectables.FDA Approval for Neffy: We discuss the rigorous testing behind Neffy’s FDA approval, including studies conducted with actual patients post-approval.Intravail Technology in Neffy Nasal Spray: Learn about the advanced technology enabling rapid, effective absorption through the nasal passages for timely intervention.Considerations for Using Neffy Nasal Spray: We explore practical aspects of Neffy’s use, from nasal congestion to potential side effects.Neffy Dosing and Side Effects: Dr. Bajowala provides insights on dosing, including when a second dose may be recommended.Helpful links:
Neffy: https://www.neffy.com/Anaphylaxis: https://allergyasthmanetwork.org/anaphylaxis/Epinephrine: https://allergyasthmanetwork.org/anaphylaxis/what-is-epinephrine/This podcast is made in partnership with The Allergy & Asthma Network. Thanks to ARS Pharma for sponsoring today’s episode. While they support the show, all opinions are our own, and sponsorship doesn’t influence our content or editorial decisions. Any mention of brands is for informational purposes and not an endorsement.
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It's that time of year again—open enrollment is here! Don't worry, we're here to help you choose the best health insurance for you and your family.
Lacey Varnon from the National Association of Medication Access and Patient Advocacy (NAMAPA) is back with Dr. Gupta and Kortney to discuss everything you need to consider when selecting a health insurance plan. This episode is all about understanding health insurance during open enrollment, from picking the right type of plan to ensuring your coverage fits your specific needs.
We cover essential aspects of open enrollment health insurance, including networks, premiums, copayments, and long-term medication coverage, so you can feel confident you're choosing a plan that works for you.
What We Cover in Our Episode on Open Enrollment Health Insurance:Key Factors to Consider: Lacey explains the importance of listing your doctors, diagnoses, and medications to ensure they're covered.Understanding Premiums, Deductibles, and Networks: Gain insight into how these elements impact your out-of-pocket costs and access to care.Plan Types – HMO, PPO, EPO, and POS: We break down each type of plan, including pros and cons, to help you decide which suits your healthcare needs.Special Considerations for Pharmacy Benefits and Long-Term Medications: Lacey offers advice on accessing necessary medications through your health plan or alternative methods if they are not covered.Navigating Open Enrollment with Family Needs in Mind: Tips on choosing a plan that considers your family member's medical needs and how you've used insurance in the past.More resources about health insurance:
Health Insurance Coverage in the United StatesWhy was my prescription denied by insurance?Health Insurance for Asthma and AllergiesChoosing the Right Health Insurance PlanNavigating Insurance Denials and Filing AppealsNAMAPA: National Association for Medication Access and Patient AdvocacyMedication Access NetworkThis episode is made in partnership with the Allergy & Asthma Network and in collaboration the National Association of Medication Access and Patient Advocacy (NAMAPA). We thank Amgen for sponsoring this episode.
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Discover Meka's journey with chronic hives in skin of color—a powerful story of resilience, self-advocacy, and building the right support system to get the care she deserves.
Emmeka, or "Meka," joins Dr. Gupta and Kortney to share her personal experience of living with chronic urticaria as a person with skin of color. Meka describes her journey from a lack of resources addressing hives on black skin to finding effective support and resources. She opens up about the long path to her diagnosis, the depth of her online research into chronic spontaneous urticaria (CSU), and the importance of finding knowledgeable, empathetic healthcare providers.
Meka’s optimism highlights how a proactive approach, a trusted care team, and a strong support network can make a difference in managing CSU.
What we cover in our episode about living with hives in black skin:Identifying Hives on Darker Skin: Meka shares the challenge of finding accurate images of hives on darker skin tones, which can complicate the first steps of recognizing your condition and create feelings of isolation.Advocating for Yourself in Healthcare: Meka provides strategies for effective self-advocacy during the diagnosis process, including tips for clear communication with healthcare providers.Building a Support Network: Meka emphasizes the value of connecting with others who share similar experiences, including support groups and online communities.Managing Symptoms & Minimizing Scars: Meka offers practical advice for managing CSU symptoms, reducing scarring, and strategies to avoid scratching. -
Chronic hives (urticaria) don’t look the same on everyone, and for people with skin of color, this can lead to confusion, misdiagnosis, and frustrating delays in treatment.
Dr. Ama Alexis joins Dr. Gupta and Kortney to discuss the unique challenges of diagnosing and managing urticaria in skin of color. Chronic spontaneous urticaria (CSU) can be especially tricky to identify in patients with darker skin tones, where traditional medical resources and visual aids often fall short.
Dr. Alexis explains how CSU appears differently in skin of color, discussing the difficulty of capturing hives on black and brown skin and offering advice for photographing hives to share with your doctor.
Dr. Gupta and Dr. Alexis also delve into the lack of diversity in clinical research and medical literature, exploring how these gaps contribute to mistrust and delays in treatment for patients of color. We end with a discussion on whether patients have better outcomes with providers who reflect the patient’s background.
What we cover in our episode about chronic urticaria in skin of color:Identifying CSU in Darker Skin Tones: Dr. Alexis shares insights on how hives appear on darker skin and gives tips for photographing hives accurately.Limited Visual Resources for Skin of Color: We discuss how a lack of reliable images for darker skin often leads to confusion and feelings of isolation.Provider Training and Diagnosis Delays: Dr. Alexis highlights how limited training in diagnosing skin conditions across all skin tones contributes to delays in care.Collaborating on a Treatment Plan: Tips for patients on advocating for inclusive care, with guidance on both over-the-counter and prescription options.Cultural Sensitivity in Healthcare: Dr. Alexis shares ways healthcare providers can foster shared decision-making to improve outcomes for patients of color.More resources about chronic hives in skin of color:
Chronic Urticaria Management, Resources & Glossary of TermsWhat is Chronic UrticariaChronic Hives: 10 Actions to Support Mental HealthChronic Spontaneous Urticaria SeriesThis episode is produced in partnership with Allergy & Asthma Network, with special thanks to Genentech for sponsoring this episode.
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Are you frustrated by the health insurance approval process for medication?
Many patients may not know what their doctors are doing behind the scenes when dealing with health insurance, and many doctors may feel overwhelmed by this process. There is a silver lining! Tools exist to help patients and providers better navigate the complexities of health insurance.
Elizabeth Johnson joins Dr. G and Kortney to share her expertise on overcoming the hurdles of securing medication approvals. She explains the biggest challenges healthcare providers face when working with insurance companies. She offers practical tips to navigate the approval process more efficiently.
Together with Dr. G, they discuss the lack of health insurance education for providers and the burden this places on medical staff. They also explore available resources and tools for healthcare professionals and stress the importance of incorporating insurance education early in medical training.
What we cover in our episode about health insurance from the provider’s side:Provider Challenges: Elizabeth explains the common hurdles doctors face in securing medication approvals, from paperwork to insurance denials.Navigating Insurance Companies: We explore the complexities of insurance approvals, from prior authorizations to the importance of good note-taking.NAMAPA Toolkit: Elizabeth introduces the NAMAPA toolkit, designed to assist healthcare providers in navigating all aspects of health insurance.Insurance Education: We highlight the need for insurance education during med school, residency and fellowship.Health Insurance Resources: Elizabeth shares strategies to ensure healthcare professionals have the tools to handle medication approvals and the resources available from pharmaceutical companies.More resources:
Medication Access Coordinator Training From NAMAPAHealth Insurance Coverage in the United StatesWhy was my prescription denied by insurance?Health Insurance for Asthma and AllergiesChoosing the Right Health Insurance PlanNavigating Insurance Denials and Filing AppealsNAMAPA: National Association for Medication Access and Patient AdvocacyMedication Access NetworkMedicoCX -
Has your medication been denied? Now what?
Before patients can access medications—whether it’s inhalers or biologic therapies—they often have to jump through many hoops to get insurance approval. Navigating the world of health insurance approvals for medication can be overwhelming for both patients and providers. In this episode, we break down what to expect, what you can do, and how to advocate for yourself throughout the process.
Lacey Varnon from the National Association of Medication Access and Patient Advocacy (NAMAPA) joins Dr. G and Kortney to dive into the complex world of health insurance. Lacey shares insights into common reasons for medication denials, how to appeal them, and how patients and healthcare providers can work together for better outcomes.
What We Cover in Our Episode About Health Insurance Approvals for Medications:Health Insurance Basics: Understanding essential terms like payer and formulary.Navigating Insurance Approvals: Tips for a smoother process, understanding prior authorization, and common reasons for medication denials.Teamwork Between Patients and Providers: How patients and doctors can collaborate to improve chances of approval and streamline the documentation process.The Appeals Process: A step-by-step guide to appealing denials and ensuring access to necessary treatments.Support Programs & Resources: Insights into sample programs, bridge programs, and tools to help patients through the approval process.More resources about health insurance denials and appeals:
Health Insurance Coverage in the United StatesWhy was my prescription denied by insurance?Health Insurance for Asthma and AllergiesChoosing the Right Health Insurance PlanNavigating Insurance Denials and Filing AppealsNAMAPA: National Association for Medication Access and Patient AdvocacyMedication Access NetworkThis episode is made in collaboration with the National Association of Medication Access and Patient Advocacy (NAMAPA). We thank Amgen for sponsoring this episode.
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Are you curious about how biologic medications are transforming the treatment of asthma, eczema, allergies, and more?
Dr. Perdita Permaul joins Dr. Gupta and Kortney to discuss the available biologic medications for allergic conditions. We walk through the eight biologics currently available for allergic diseases, explaining how these medications target different parts of the immune system to treat allergic conditions more effectively than traditional medications.
Dr. Permaul explains how biologics have evolved since 2003 and how they are changing the way allergic conditions are treated. She also explains why some of the biologics treat multiple diseases, whereas some are only approved for one.
What we cover in our episode about the available biologics for allergic conditionsHow biologics work for allergic conditions: We unpack how biologic medications target specific parts of the immune system, reducing inflammation and improving the quality of life for patients with allergic diseases.History and evolution of biologics: Dr. Permaul walks us through the timeline of biologics, starting with Xolair in 2003 and how these treatments have expanded to target other conditions over time.Which biologics treat which conditions: From asthma and eczema to food allergies and nasal polyps, we break down which biologics are available and how they help patients with allergic conditions.Future of biologics: Dr. Permaul discusses the potential of biologics to be used for more conditions in the future, including ongoing research into food allergy treatments.Biologics Cheat Sheet
Below is a list of the 8 biologics discussed in this episode. We have briefly outlined their mechanism of action along with the approved conditions and ages the drug is available for presecription.
Omalizumab (Xolair)
Xolair works by binding to IgE to prevent allergic reactions. It has since been approved for chronic hives, nasal polyps, and food allergies.
Allergic asthma: 6+Chronic idiopathic urticaria (hives: 12+Chronic rhinosinusitis with nasal polyps (CRSwNP): 18+Food allergies:1+Mepolizumab (Nucala)
Targets and blocks interleukin-5 (IL-5) play a key role in the activation and priming of eosinophils, a type of white blood cell that causes inflammation in asthma.
Eosinophilic Asthma: 6+CRSwNP: 18+Eosinophilic Granulomatosis with Polyangiitis (EGPA): 18+Hypereosinophilic Syndrome: ≥6 monthsReslizumab (Cinqair)
Targets and blocks interleukin-5 (IL-5).
Eosinophilic asthma: 18+Benralizumab (Fasenra)
Binds to the IL-5 receptor, preventing eosinophils from growing and causing inflammation.
Eosinophilic asthma: 6+Eosinophilic Granulomatosis with Polyangiitis (EGPA): 18+Dupilumab (Dupixent)
Targets and blocks IL-4 and IL-13 to reduce inflammation
Asthma: 6+Atopic Dermatitis: 6 months+CRSwNP: 18+Eosinophilic Esophagitis (EoE): 1+ (> 33 lbs)Approved for prurigo nodularis (PN): 18+Tezepelumab (Tezspire)
Blocks thymic stromal lymphopoietin (TSLP).
Asthma: 12+Tralokinumab (Adbry, Adtralza)
Targets and neutralizes interleukin-13 (IL-13).
Atopic dermatitis: 12+Lebrikizumab (Ebglyss)
Targets and neutralizes interleukin-13 (IL-13).
Atopic dermatitis: 12+ (> 40 lbs)________
This podcast is made in partnership with The Allergy & Asthma Network. Thanks to Sanofi-Regeneron for sponsoring today’s episode. While they support the show, all opinions are our own, and sponsorship doesn’t influence our content or editorial decisions. Any mention of brands is for informational purposes and not an endorsement.
Disclaimer: This podcast is for informational purposes only and does not substitute professional medical advice. Always consult with your healthcare provider for any medical concerns.
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Do food allergies impact all communities in the same way?
Dr. Vivian Hernandez-Trujillo joins Dr. G and Kortney to discuss the impact of health disparities on allergy outcomes within the Hispanic and Latino communities. Dr. Hernandez-Trujillo highlights the challenges posed by immigration status, language barriers, and cultural factors that contribute to unequal access to healthcare. These disparities often lead to difficulties in managing conditions like food allergies and asthma.
Dr. Hernandez-Trujillo emphasizes the importance of having an advocate in the healthcare system. Dr. G and Dr. Henandez-Trujillo discuss how building a strong relationship with your doctor is key to better outcomes.
Dr. Hernandez-Trujillo also addresses how cultural beliefs and practices within the Hispanic community influence the understanding and management of food allergies and the need for healthcare providers to enhance their cultural competency.
What we cover in our episode about health disparities in the Hispanic and Latino Communities:Health Disparities: Immigration status and language barriers significantly impact healthcare access and outcomes in the Hispanic community.Role of an Advocate: Why it is important to have an advocate and maintain a strong relationship with your healthcare provider to navigate the healthcare system.Challenges with Allergy Testing: What are the difficulties the Hispanic population faces with allergy testing, including issues related to insurance coverage?Cultural Beliefs and Practices: How cultural beliefs and practices within the Hispanic community influence the understanding and management of food allergies.Cultural Competency: How healthcare providers can enhance their cultural competency to better serve Hispanic patients.About Our GuestDr. Vivian Hernandez-Trujillo is a board-certified allergist and immunologist at Nicklaus Children’s Hospital, where she specializes in treating allergies and immune conditions in children. Dr. Hernandez-Trujillo is deeply committed to addressing health disparities and improving healthcare access for underserved communities. She is actively involved in research and education, focusing on culturally competent care and advocating for patients within the Hispanic community. Her clinical interests include food allergies, asthma, and other allergic conditions.
More resources about XXX:
¿Qué es una alergia alimentaria?GoogRx Espagñol Serie de conferencias virtuales Unidos Hablemos -
Starting biologic therapy can be life-changing, but navigating the process isn’t always easy.
Dr. William Anderson joins Dr. Gupta and Kortney to break down the essential steps for starting biologic therapy, covering everything you need to know before beginning treatment. Biologics are at the forefront of managing chronic allergic diseases like asthma and eczema, offering targeted, personalized care that can improve patients’ quality of life. However, accessing these medications often requires navigating a maze of insurance approvals, prior authorizations, and specialty pharmacies.
We dive deep into the challenges patients face when starting biologics—understanding how to get coverage, managing co-pays, and coordinating with specialty pharmacies, all while handling the logistics of administering the medication. As someone who has just started a biologic herself, Kortney shares her own experience and reflects on how this episode provides the exact information she wished she’d had a few months ago.
What we cover in our episode about starting a biologic medicationGetting informed before starting biologic therapy: Dr. Anderson explains why reviewing your medication’s patient website is a great first step. These resources often include videos and important details about the treatment.Navigating insurance and coverage: Insurance is often the biggest hurdle to starting biologics. Dr. Anderson highlights the role your doctor plays in this. Additionally, we discuss the importance of understanding your coverage, prior authorization, and working with specialty pharmacies to ensure you get the medication.Administration and storage of biologics: Whether it’s self-injection or infusion at a clinic, we explain how biologics are administered. Dr. Anderson also provides tips on proper storage, including refrigeration and traveling with biologics.Vaccines and biologics: Find out whether patients on biologic therapy should avoid live vaccines and how inactivated vaccines like the flu shot are generally safe to take.Long-term planning for biologics: Learn about the regular follow-ups and monitoring that are part of managing biologic therapy. Dr. Anderson discusses the importance of staying on track with your doses and follow-up appointments to ensure your biologic works effectively.About our biologics expert, Dr. William Anderson
Dr. William Anderson, is a board-certified pediatric allergist and immunologist at Children’s Hospital Colorado. With a focus on treating children with complex allergic conditions such as asthma, eczema, and food allergies, Dr. Anderson is known for his patient-centered approach. He has extensive experience in biologic therapies and is dedicated to improving the quality of life for patients through personalized care. Dr. Anderson also actively participates in clinical research, staying at the forefront of advances in allergy and immunology treatments.
More resources about biologic therapies and the conditions they treat:
A systematic review and expert Delphi Consensus recommendation on the use of vaccines in patients receiving dupilumab: A position paper of the American College of Allergy, Asthma and ImmunologyBiologic Medications OverviewUnderstanding AsthmaAllergies ExplainedManaging Food AllergiesUnderstanding EczemaWhat if I Can’t Afford My Eczema Medication?What if I Can’t Afford My Asthma Medication?This podcast is made in partnership with The Allergy & Asthma Network. Thanks to Sanofi-Regeneron for sponsoring today’s episode. While they support the show, all opinions are our own, and sponsorship doesn’t influence our content or editorial decisions. Any mention of brands is for informational purposes and not an endorsement.
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Curious about what’s fact and what’s fiction when it comes to biologic medications?
We’re uncovering the truth behind the most pervasive myths about biologic medications with guest Dr. Cedric “Jamie” Rutland. Biologics are revolutionizing the treatment of allergic diseases like asthma and eczema, but misconceptions about their effectiveness, safety, and usage still persist. Dr. Rutland sets the record straight, debunking myths that may be clouding your understanding and decision-making process.
From whether biologics are a cure to concerns about long-term safety and side effects, this episode tackles the most common myths head-on. Dr. Rutland breaks down what biologic therapy truly offers, helping you make informed decisions about your treatment options.
What we cover in our episode about biologics factsAre biologics a cure? Dr. Rutland explains that biologics help manage symptoms, but they are not a complete cure.Biologics vs. traditional medications: We clarify how biologics differ from traditional medications in the way they target the immune system at a molecular level.Do biologics have severe side effects? We dispel myths about severe side effects.Long-term effectiveness of biologics: Dr. Rutland talks about how biologics maintain effectiveness over time for most patients.Do you have to stay on biologics for life? Learn how long patients typically stay on biologic treatments and whether they are lifelong therapies.When should biologics be considered? We address the myth that biologics are only for when all other treatments have failed and discuss when biologics should be introduced.Can you stop other medications while on biologics? Dr. Rutland explains that biologics are often used alongside other medications, not as a replacement.Who can use biologics? We debunk the myth that biologics are only for adults or that they can't be used if you have multiple health issues.Biologics and cancer risk: A common concern, but Dr. Rutland explains the actual risks and dispels the misconception that biologics cause cancer.Are biologics immunosuppressive? We discuss how biologics work on the immune system without broadly suppressing it like other treatments might.Biologics in medical practice: Dr. Rutland talks about the role of doctors and financial incentives, explaining why doctors prescribe biologics and how they make treatment decisions.Do biologics work immediately? Dr. Rutland sets the record straight on how long it typically takes for biologics to start working.Biologics are not experimental: Biologics have been widely studied and are not experimental treatments.Administration of biologics: We address the myth that biologics must be administered only in hospitals, explaining how patients can receive them at home or in clinics.Biologics are not interchangeable: Dr. Rutland explains the importance of sticking with the biologic prescribed specifically for a patient's condition.Prescribing biologics: While specialists typically prescribe biologics, we explore how general practitioners can also be involved in the process.Lifestyle changes and biologics: We discuss the misconception that biologics eliminate the need for lifestyle changes.Are biologics unnecessary for mild symptoms? Dr. Rutland explains that biologics are not only for severe symptoms but can also be considered for other cases.More resources about biologic therapy and the conditions they treat:
https://biologicmeds.org/https://allergyasthmanetwork.org/what-is-asthma/https://allergyasthmanetwork.org/allergies/https://allergyasthmanetwork.org/food-allergies/https://allergyasthmanetwork.org/what-is-eczema/ -
What are biologic medications, and how can they help people with allergic diseases?
We discuss biologic medications with Dr. Berger, a leading expert in biologic therapy for allergic diseases. Since the first biologic was introduced in 2003, these treatments have advanced significantly. By targeting the root causes of inflammation, biologics offer a more precise, personalized approach to treating conditions like asthma and eczema. Unlike traditional medications, biologics are a breakthrough, opening the door to tailored care that improves patients' long-term symptom control and quality of life.
Dr. Berger explains biologic medications, how they work at a molecular level, and how they impact the immune system. As Kortney recently started biologic therapy, we also get a firsthand account of patients' decision-making process and concerns when considering biologic treatments. These innovative therapies not only control symptoms but can transform the daily lives of people living with chronic allergic diseases, providing hope for better, long-term outcomes.
What we cover in this episode about the basics of biologic medications:What is a biologic medication? Dr. Berger explains how biologic medications differ from traditional treatments by focusing on precision-based medicine, offering a revolutionary way to target specific aspects of the immune system.How biologic therapies target molecular inflammation: Learn how biologic treatments act on specific inflammatory molecules, offering hope for better control and relief for patients with severe asthma, eczema, and more.Do biologics suppress the immune system? We address common questions about biologic therapy, its effects on the immune system, and potential side effects.The evolution of biologic treatments. A look at how biologic medicine has advanced since 2003 and its role in reshaping asthma therapy and other allergic disease treatments, providing exciting new options for patients.Improving quality of life for allergic disease patients with biologics. We discuss how, for many, biologics have been life-changing.Steps for patients considering biologic treatment. Dr. Berger offers practical advice for patients interested in discussing biologic therapy with their healthcare providers.About our biologic medication expert - Dr. BergerDr. William E. Berger is a past Clinical Professor in the Department of Pediatrics at the University of California-Irvine and served as Medical Director of Southern California Research in Mission Viejo. He is a board-certified allergist and immunologist with a distinguished career, including roles as President of the American College of Allergy, Asthma & Immunology and as Medical Staff Allergist for the U.S. Olympic Swim Team. Dr. Berger has published over 200 peer-reviewed articles and authored books like Asthma for Dummies, focusing on allergy and asthma treatments. He is widely recognized as an expert in his field, frequently appearing on major media outlets like CNN and Good Morning America.
More resources about biologic therapy:
https://biologicmeds.org/https://allergyasthmanetwork.org/what-is-asthma/https://allergyasthmanetwork.org/allergies/https://allergyasthmanetwork.org/food-allergies/https://allergyasthmanetwork.org/what-is-eczema/This podcast is made in partnership with The Allergy & Asthma Network. Thanks to Sanofi-Regeneron for sponsoring today’s episode. While they support the show, all opinions are our own, and sponsorship doesn’t influence our content or editorial decisions. Any mention of brands is for informational purposes and not an endorsement.
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There’s never been a better time to be a CSU patient, with cutting-edge therapies and revolutionary treatments just around the corner. As research accelerates, new and promising options that could significantly improve the quality of life for those living with Chronic Spontaneous Urticaria are coming to market.
In this episode, Dr. Matthew Zirwas joins us to discuss the latest advancements in treating CSU, offering invaluable insights into both current and emerging treatment options. With his extensive experience and patient-centred approach, Dr. Zirwas breaks down the complexities of CSU and highlights how these new therapies can make a real difference.
This podcast was made in partnership with Allergy & Asthma Network. We thank Novartis for sponsoring this podcast.
What We Cover in Our Episode About Emerging Chronic Spontaneous Urticaria Treatments:How Dr. Zirwas explains CSU to his patients: Discover the patient-friendly explanations that help demystify CSU and empower patients to learn more about their disease.When to start with a biologic: Learn about the decision-making process for initiating biologic therapies like Xolair (omalizumab) and when they are most appropriate.The new medications coming to market: Get an overview of the latest advancements, including:Dupixent (dupilumab): A biologic administered via injection that targets key pathways in the inflammatory response.Remibrutinib: A BTK (Bruton tyrosine kinase) inhibitor available as a pill that blocks a crucial enzyme in mast cell activation.Barzolvolimab: A promising biologic that targets the C KIT receptor on mast cells to reduce their number.Shared decision-making with these medications: Explore strategies for choosing the most appropriate treatment in a rapidly evolving therapeutic landscape.Research into the underlying cause of CSU: What’s happening on the research front to uncover the root causes of CSU.About Our GuestDr. Matthew Zirwas, MD, is a board-certified dermatologist and a nationally recognized expert in allergy patch testing, psoriasis, and eczema. He founded the Bexley Dermatology Research Clinic, offering patients access to the latest treatment options before they are widely available. Dr. Zirwas also serves as a dermatologic advisor for several companies, including ALL Laundry Detergent and Cerave, and contributes to Women’s Health Magazine. Learn more about Dr. Zirwas.
More resources about chronic spontaneous urticaria:
Chronic Urticaria Management, Resources & Glossary of Terms: https://allergyasthmanetwork.org/health-a-z/chronic-urticaria/management-and-resources/What is Chronic Urticaria: https://allergyasthmanetwork.org/health-a-z/chronic-urticaria/ More information about Omalizumab (Xolair): https://www.xolair.com/chronic-spontaneous-urticaria.htmlDisclaimer: This podcast is for informational purposes only and does not substitute professional medical advice. Always consult with your healthcare provider for any medical concerns.
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Did you know that the month of September sees a drastic rise in asthma attacks and hospitalizations?
Dr. G and Kortney delve into the challenges that asthmatics face during the fall season, also known as "peak week." Despite what the name suggests, asthma cases start to rise in the second week of September and continue into early October before returning to normal levels.
We begin by defining asthma and then explore why asthma attacks are more prevalent in September. We discuss the role of germs and viruses, indoor and outdoor allergens, and cold weather in exacerbating asthma symptoms. Dr. G also shares tips on how to lessen your exposure to these triggers. Additionally, we cover the importance of having an asthma action plan and the significance of well-controlled asthma.
Dr. G also discusses the financial aspects of asthma management and offers advice on how to discuss this with your doctor.
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What we cover in our episode about the rise in September asthma attacksWhy September is Peak Asthma Season: Explore why asthma attacks increase in the fall and what you can do to prepare.The Role of Germs and Viruses in Asthma: Understand how illnesses can trigger asthma and learn tips for staying healthy.Indoor and Outdoor Allergens: Discover how common allergens like dust mites, pet dander, ragweed, and mold can affect asthma, and what you can do to limit exposure.Preparing for Peak Week: Essential steps to take before asthma season hits, including scheduling doctor visits and creating an action plan.Asthma Management Tips for Different Age Groups: Advice for school-aged children and elderly patients to ensure they receive the best care.More resources about asthma peak week:
Asthma and Allergy Forecast: pollen and allergen count https://allergyasthmanetwork.org/weather/10 Ways to Stay Healthy During the September Asthma Peak Week https://allergyasthmanetwork.org/news/10-ways-to-stay-healthy-during-september-asthma-peak/Seasonal allergies: https://allergyasthmanetwork.org/news/seasonal-allergies/Asthma attack: https://allergyasthmanetwork.org/what-is-asthma/asthma-attack/What if I Can’t Afford My Asthma Medication? https://allergyasthmanetwork.org/what-is-asthma/what-if-i-cant-afford-my-asthma-medication/ Asthma Management and Control (2:2:1 Rule) https://allergyasthmanetwork.org/what-is-asthma/asthma-management-and-control/AirQ https://www.airqscore.com/en/main-page.html ACT Test https://www.asthmacontroltest.com/welcome/We want to thank AstraZeneca for sponsoring this episode.
Disclaimer: This podcast is for informational purposes only and does not substitute professional medical advice. Always consult with your healthcare provider for any medical concerns.
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This episode is a quick-fire round covering the misunderstood aspects of chronic spontaneous urticaria (CSU), a condition that perplexes many due to its spontaneous nature. With over 1.7 million people affected, it's more common than you might think and deserves a closer look. Despite its prevalence, many misconceptions persist about what causes CSU, its symptoms, and how it can be treated.
Kortney and Dr. Gupta tackle the myths and misconceptions around CSU. Unpacking its impacts on quality of life and the challenges those living with the condition face. They explore the realities of living with CSU, from the pervasive itch to the emotional toll it can take. Whether you're a patient, caregiver, or healthcare professional, this episode offers valuable insights into the realities of managing CSU.
This podcast was made in partnership with Allergy & Asthma Network. We thank Novartis for sponsoring this podcast.
The chronic spontaneous urticaria myths and misconceptions we cover in our episodeCSU is caused by allergies.CSU is contagious.CSU is a rare condition.CSU is not a serious condition.Stress is the main cause of CSU.CSU only affects the skin.CSU will go away quickly.There isn’t any treatment for chronic hives.Antihistamines are the only treatment for CSU.Changing your diet will help CSU.CSU can be cured.Once CSU goes away, it will never come back again.Men and women are equally affected by CSU.You can always pinpoint the exact cause of hives in patients with CSU.Autoimmune conditions are more common in people with CSU.Scratching hives is harmless.Once my hives are controlled, I need to be on the medication forever.All hives look the same.Only adults get CSU.CSU hives are always accompanied by other allergic symptoms like swelling or difficulty breathing.Having CSU doesn’t affect quality of life.The itch in CSU is not a big deal.Allergy testing will help me figure out why I have CSU.More resources about chronic spontaneous urticaria:
Chronic Urticaria Management, Resources & Glossary of Terms: https://allergyasthmanetwork.org/health-a-z/chronic-urticaria/management-and-resources/What is Chronic Urticaria: https://allergyasthmanetwork.org/health-a-z/chronic-urticaria/ More information about Omalizumab (Xolair): https://www.xolair.com/chronic-spontaneous-urticaria.htmlDisclaimer: This podcast is for informational purposes only and does not substitute professional medical advice. Always consult with your healthcare provider for any medical concerns.
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Imagine being so itchy that you’d consider cutting off your skin just for relief. That’s what it can be like living with chronic spontaneous urticaria.
We sit down with Heather, a patient living with chronic spontaneous urticaria, as she candidly shares her experiences from the initial diagnosis to navigating the complex landscape of treatments and mental health support. Her story sheds light on the day-to-day struggles and triumphs of managing CSU, offering hope and practical advice for those in similar situations.
Dr. G unpacks Heather's diagnosis and treatment journey, including antihistamines and Omalizumab. Dr. G also highlights the importance of managing mental health. Kortney shares her experience of itch and, with Heather, discusses the impact of chronic itching on quality of life and how to explain this to friends and family.
What we cover in our episode about living with chronic spontaneous urticariaHeather's Journey with CSU: Heather shares her initial diagnosis and the rollercoaster of emotions and challenges that followed.Anaphylaxis vs. CSU: Understanding the critical differences between these two conditions.Finding the Right Treatment Plan: The journey to discovering effective medications like antihistamines and the injectable - Omalizumab (Xolair).Mental Health Support: The importance of therapy and online resources in managing life with CSU.Management strategies: Heather shares what works for her in managing exacerbating situations. Advice for New Patients: Heather offers valuable advice for those beginning their CSU journey.More resources about chronic spontaneous urticaria:
Chronic Urticaria Management, Resources & Glossary of Terms: https://allergyasthmanetwork.org/health-a-z/chronic-urticaria/management-and-resources/What is Chronic Urticaria: https://allergyasthmanetwork.org/health-a-z/chronic-urticaria/ More information about Omalizumab (Xolair): https://www.xolair.com/chronic-spontaneous-urticaria.htmlEpisode Heather talks about where she learned to call her condition Lynda: https://www.itchpodcast.com/episodes/71-living-with-mastocytosisDisclaimer: This podcast is for informational purposes only and does not substitute professional medical advice. Always consult with your healthcare provider for any medical concerns.
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Yes, there are more options than antihistamines to treat chronic spontaneous urticaria. We dive into them!
Dr. Sheila Gogate joins us to discuss the chronic spontaneous urticaria (CSU) treatments currently available for patients. Dr. Shaila Gogate outlines the treatment journey for CSU with an emphasis on shared decision-making.
This episode emphasizes the importance of following treatment guidelines and adjusting medications as needed. We discuss the available treatments for urticaria, including antihistamines, omalizumab (Xolair for hives), and Cyclosporine. The episode also explores the journey of managing CSU symptoms through both medical and non-medical approaches.
What we cover in our episode about chronic spontaneous urticaria treatmentsTreatment Path and Guidelines: Overview of doctors' steps to treat CSU. The importance of shared decision-making in the treatment plan. Antihistamines: Role of oral antihistamines and H2 blockers in managing hives, dosing options, side effects, when to change medications, and how to choose the right antihistamine.Advanced Treatments: If antihistamines fail, the following steps include omalizumab (Xolair) injections or Cyclosporine. An overview of both dosing options and side effects.Emerging Therapies: Treatments like Remibrutinib and Dupilumab.Quality of Life and Non-Medical Management: The Urticaria Activity Score (UAS7). Mental health screening for CSU patients and strategies like stress reduction and if special diets are effective.About our guest, Dr. Shaila GogateDr. Shaila Gogate, board-certified by the American Board of Allergy & Immunology, has been with Colorado Allergy & Asthma Centers since 2014. She completed her medical education at Chicago Medical School, her residency at Washington University, and her fellowship at National Jewish Health in Denver. Dr. Gogate has served as an Assistant Professor at the University of Colorado, has extensive clinical research experience, and emphasizes strong patient-provider communication to develop effective treatment plans.
More resources about chronic spontaneous urticaria:
Chronic Urticaria Management, Resources & Glossary of Terms: https://allergyasthmanetwork.org/health-a-z/chronic-urticaria/management-and-resources/What is Chronic Urticaria: https://allergyasthmanetwork.org/health-a-z/chronic-urticaria/ How Mast Cells Work Video_ mast cell video - explanation of mast cell (07:20): https://youtu.be/OF7tBIvMK_0?si=osJaIpTrivUP1OwrUrticaria Activity Score (uas7): https://www.mdcalc.com/calc/10226/urticaria-activity-score-uasMore information about XOlair: https://www.xolair.com/chronic-spontaneous-urticaria.html
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How is the black community impacted by food allergies?
Dr. Carla Davis joins Dr. G and Kortney to discuss the impact of social determinants of health on food allergy outcomes within the Black community. Dr. Davis highlights historical factors like redlining and insurance disparities that exacerbate health disparities, resulting in higher prevalence rates of food allergies and multiple allergies among Black patients. These disparities often lead to increased emergency room visits and barriers to accessing allergen-free foods, compounded by socioeconomic challenges and food insecurity.
Dr. Davis also underscores how cultural differences significantly influence the management of food allergies within families, particularly during gatherings, and emphasizes the crucial role of media representation in raising awareness and promoting acceptance.
We discuss the critical need for increased Black representation in research trials, recognizing the challenges posed by longstanding mistrust in the medical community among Black patients.
Key Points Covered in This Episode:
Health Disparities: Social factors significantly impact food allergy outcomes in the Black community.Limited Healthcare Access: Redlining and insurance disparities restrict healthcare access, worsening health outcomes.Food Insecurity: Challenges in accessing allergen-free foods are heightened by food insecurities and food deserts.Cultural Factors in Food Allergy Management: Cultural influences play a crucial role in managing food allergies within families.Resources for Food Allergies: Essential support from food banks and allergy organizations for managing allergies and food insecurity.Communication Tips for Patients: Practical advice for effective communication and advocacy with healthcare providers.Historical Mistrust of the Medical Community: Historical discrimination contributes to mistrust in healthcare, affecting access and outcomes.Helpful Resources
Health Disparities in Allergy, Asthma and Immunologic Diseases (New Webinar July 16, 2024): https://allergyasthmanetwork.org/webinars-updates/health-disparities-diseases/Black People Like Me Virtual Conference Series 2024: https://allergyasthmanetwork.org/trusted-messengers-project/black-people-like-me-2024/Food Allergy Resources: https://allergyasthmanetwork.org/allergies/ School Plans for Students with Food Allergies: https://allergyasthmanetwork.org/news/school-plans-students-food-allergies/Food Equality Initiative - Food Allergy Friendly Food Bank Resource: https://www.foodequalityinitiative.org/
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How do you know if your hives are chronic spontaneous urticaria?
Join Kortney and Dr. Payel Gupta in the second episode of this chronic spontaneous urticaria (CSU) series as they delve into the diagnostic journey of CSU.
Have you wondered if the path to a chronic spontaneous urticaria diagnosis is long? CSU can feel like a very complex disease to diagnose due to the lack of identifiable triggers, but this episode breaks down the steps healthcare professionals take to diagnose CSU.
Dr. G clarifies how allergists' and dermatologists' roles differ in diagnosing CSU. The episode emphasizes the importance of a detailed medical history and the tests involved in ruling out other conditions. It also describes the journey of determining CSU from other skin and allergic reactions through meticulous evaluation and specific testing methods.
What we cover in our episode about diagnosing Chronic Spontaneous Urticaria:Introduction to CSU Diagnosis: CSU has no identifiable triggers, making diagnosis a process of elimination.Role of Specialists: Patients often start their diagnosis journey at urgent care, after which they consult allergists and dermatologists depending on the severity and symptoms of hives.Detailed Medical History: Essential questions cover medications, infections, travel history, and other health changes to rule out underlying causes.Physical Examination: Doctors check if hives are “blanchable” to differentiate from other conditions like vasculitis.Ruling out other Conditions: This involves evaluating other conditions in which hives are a symptom, such as mast cell disease or various autoimmune diseases. Necessary Tests: Doctor’s apprehension about doing a food allergy test unless necessary. Other tests include looking at blood count (CBC with differential) and inflammation (ESR or CRP).More resources about chronic spontaneous urticaria:
Chronic Urticaria Management, Resources & Glossary of Terms: https://allergyasthmanetwork.org/health-a-z/chronic-urticaria/management-and-resources/What is Chronic Urticaria: https://allergyasthmanetwork.org/health-a-z/chronic-urticariThis episode is produced in partnership with Allergy & Asthma Network. We want to thank Novartis for sponsoring this episode.
Disclaimer: This podcast is for informational purposes only and does not substitute professional medical advice. Always consult with your healthcare provider for any medical concerns.
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