Episodi
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In todayâs episode, Evgeny Lebedev talks about the remarkable potential of ketamine with Dr John Krystal, Professor of neuroscience at the Yale School of Medicine.
Their discussion delves into the world of neurology, what ketamine actually does to our brain and the importance of glutamate receptors in treating depression. Ketamine may have gotten bad press after Friends actor Matthew Perry died of an overdose while receiving treatment with the drug, but for Dr Krystal, it is a critically overlooked solution to the epidemic of mental illness.
Also in this episode:
Ketamineâs complicated history starting in the 1950sThe real reason depression leads to suicideWhy ketamine is effective at dealing with traumaThe detailed procedure of ketamine therapy The importance of ketamineâs ânarrow windowâ dosageKetamineâs reputation and why it needs to changeHosted on Acast. See acast.com/privacy for more information.
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In todayâs episode, we are excited to be joined by Peter Attia: a longevity expert, physician, and bestselling author.
Peterâs podcast, The Drive, is one of the most popular in the world. Through it, heâs brought cutting edge science to the masses, sharing tips and tricks, some of which are still experimental, on how to boost your chances of ageing well.
Tune into Peter and Evgenyâs conversation on what the former calls âMedicine 3.0â â his blueprint for good health â and how happiness is essential to longevity, not just a bonus. âIt doesnât matter how healthy you are,â Peter says, âif the most important relationships in your life are not happy.â
Topics covered include:
The difference between health span and lifespanHow AI can revolutionise clinical trials and the development of new medicines â How to regulate glucose levelsTips to reducing caloric intakeWhy cancer immunity is under-researchedHow to prevent heart diseaseâ Debunking the biggest myths around nutritionHosted on Acast. See acast.com/privacy for more information.
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Episodi mancanti?
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Evgeny Lebedev joins Dr. Aubrey de Grey, a visionary in biomedical gerontology and co-founder of the SENS Research Foundation.
Known for his radical approach to ageing, Dr. de Grey discusses why some need to awaken from a "pro-ageing trance".
Whatâs Aubreyâs biological age?
In this episode:
Why we donât âhaveâ to ageReversing cellular agingThe ethical questions surrounding life extensionThe societal shifts we might expect if ageing becomes a treatable conditionThe science behind extending the human healthspanPlus more.
Hosted on Acast. See acast.com/privacy for more information.
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On todayâs show Evgeny Lebedev is in conversation with the Oscar-winning actor, Dame Helen Mirren.
They discuss everything from the evolution of fashion to the contemporary media landscape.
âItâs so sad that Kurt Cobain died when he did, because he never got to see GPSâ
Also in this episode:
The evolution of technology and why Helen is grateful to have been around in a world without itHow young people rediscover previously forgotten tech and bring it back to lifeHelen reflects on spirituality, the power of belief and how it shapes our lives, but why she doesn't believe in God.Russian heritage and the complexities of her identityHow Helen stays youthful, both in body and mindHosted on Acast. See acast.com/privacy for more information.
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Evgeny Lebedev is joined by Jim Poole, chairman, president and chief executive of neuroscience company Solace Life Sciences.
The company owns NuCalm, a technology designed to reduce stress and improve sleep without recourse to drugs.
You may have even spotted the Duchess of Sussex wearing one of their stress relief patches.
In this episode, Evgeny and Jim explore the evolution of the human brain, anxiety and how to deregulate the amygdala, a small, almond-shaped part of the brain that plays a central role, which Jim says âfeeds on fearâ.
In this episode:
The current state of brain understandingBrain psychology and its evolutionThe autonomic nervous system and how it shapes everything from stress to relaxationHo to control anxious thoughtsHow to downregulate the amygdala, the part of the brain that triggers intense fear responsesDifferent frequencies in the brain and how they influence mental statesWhy âthe Western world may be leading the causeâ of anxietyHosted on Acast. See acast.com/privacy for more information.
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Weâre joined by one of the most famous faces of alternative medicine on the planet, Deepak Chopra.
The world-renowned author, health and wellness expert has been at the intersection of science and spirituality for nearly 50 years.
Deepak sits down with host Evgeny Lebedev to mark the release of his 95th book âDigital Dharmaâ. He explains why artificial intelligence is the key to unlocking both personal and spiritual growth, and why humanity is at a crucial crossroads with technology. One of those roads, he says, "leads to the extinction of humanity."
Other topics discussed in this episode:
Ideas for a preventative health service in the UK & beyondHow VR is going to lead the future of therapeutics Why 'living our best life' needs to be more than just a soundbite How technology can change our biology What is consciousness, and why science alone doesnât have the answerDigital Deepak, his new AI twin dispensing medical and spiritual adviceMortality and longevityGet in touch with us at [email protected]
Hosted on Acast. See acast.com/privacy for more information.
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Is there such a thing as perfect sleep? Leading expert in circadian neuroscience from Oxford University, Professor Russell Foster, joins host Evgeny Lebedev, to explain the science behind nighttime slumber and why it's crucial to living our best lives awake.
The pair discuss everything from sleep hygiene, our circadian rhythm and body clocks, the impact of technology before bed and whether it actually affects us, the myths, and even some tips to improve longevity. This episode also includes excerpts from Eight Sleep founder Matteo Franceschetti, the pop star Rita Ora, and the author and actress Davinia Taylor.
Topics discussed in this episode:
Is sleep an indulgence?How a bad culture of sleep was heightened in the 1980sCan poor sleep link to dementia?The different types of sleep: Deep and RemThe science of our dreamsUnderstanding how circadian rhythms work and how they relate to our genetic makeupThe perfect recipe for a napSleeping pills and memory lossAre sleep apps worth the hype?The critical role of body temperatureSleep myths: Cheese and dreams, sipping Horlicks and counting sheepRita Oraâs sleep routineGet in touch with us at [email protected]
Hosted on Acast. See acast.com/privacy for more information.
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On this episode of Brave New World, weâre turning our attention to nootropics and neuroscience.
Nootropics are drugs and supplements which proponents say can boost alertness, increase focus, and improve memory.
Today, Evgeny Lebedev meets Nootopia founder Mark Effinger, AKA Mr Noots. Since launching in 2004, Nootopia has helped 300,000 people- including doctors, biohackers, and fitness instructors- unlock their potential.
The two discuss:
- The Nootopia lab and its research methods
- Markâs journey from child prodigy to entrepreneur
- How the loss of his wife was the catalyst for Mark to start Nootopia
- Why everyone has an âinherent Achilles heelâ
-The complexities of ADHD treatment
-Natural ways to rebuild neural pathways
Plus moreâŠ
If you enjoyed the episode, please leave us a review and rating. The next episode will drop on 22 Aug.
Drop us a line at [email protected]
Disclaimer: you should always seek own medical advice.
Hosted on Acast. See acast.com/privacy for more information.
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In this episode of Brave New World, billionaire entrepreneur Christian Angermayer and Olympic athlete James Magnussen â who's been offered $1 million if he wins the competition's 100m freestyle swimming race â talk to Evgeny about taking part in the most radical sports event ever conceived; where doping is not just allowed but encouraged.
Christian talks about:
Dropping out of university and becoming an entrepreneur Why he believes medical psychedelics will be available to prescribe within a couple of yearsHow psychedelics can help us cope with change, AI panic and our fear of the "new reality"How Ozempic has changed the game for pharmaceutical companies Why alcohol is "the worse drug of all" How the Enhanced Games will actually improve drug testing at the Olympics How most athletes struggle to make ends meet â and how the competition will help them earn proper moneyJames talks about:
How the Enhanced Games have given him fresh purposeWhy he isnât worried about using testosterone to âjuice to the gillsâ â safe for the impact on his fertility Why stigma persists around performance enhancing drugsWhy this could become one of the biggest industries in the worldIf you enjoyed the episode, please follow, leave us a review and vote in the poll below. The next episode will drop on 8 August.
Get in touch with us at [email protected]
Hosted on Acast. See acast.com/privacy for more information.
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In this episode of Brave New World, Evgeny talks to bestselling author and brain coach Jim Kwik. Kwik suffered a traumatic brain injury aged 5 and is now a world authority on brain optimisation. He shares his top tips on how to boost cognitive function. The two discuss:
Why adding Omega 3s to your diet â and cutting out sugar â are vital to brain health.What to do with negative thoughtsWhy we need to keep moving throughout the day â and howWhy a tidy work environment can help with clarity of thoughtHow to deal with information fatigue and create boundaries between us and our devicesWhy we need to stop delegating organisational tasks to our phonesIf you enjoyed the episode, please leave us a review and rating. The next episode will drop on 25 July.
Hosted on Acast. See acast.com/privacy for more information.
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In this episode of Brave New World, Evgeny talks to physician and longevity expert Mark Hyman. The two discuss the rise of functional medicine and what lifestyle changes we can make to enhance our healthspan. They cover:
The paradigm shift happening in medicine today The underlying mechanisms that drive dysfunction and diseaseHow nutrition and exercise impact the pathways of ageing Insulin resistance and the effect of UPFs Why we should be eating animal protein and fat for breakfast, and fasting overnightWhy we need to pay more attention to mitochondria The benefits of strength training, saunas and cold plunges Why it's never too late to start making lifestyle changes to enhance longevityIf you enjoyed the episode, please leave us a review and rating. The next episode will drop on 11 July.
Hosted on Acast. See acast.com/privacy for more information.
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In this episode of Brave New World, Evgeny talks to author and podcaster Ryan Holiday about the modern media landscape, echo chambers and the value of Stoic leadership. The two discuss:
The common misunderstanding of stoicism as apathyWhy we need stoicism now more than everWhy it's so hard to be stoic in the information ageWhy we ought to be more cautious about live news What other world leaders can learn from President Kennedy during the 1962 MissileIf you enjoyed the episode, please leave us a review and follow. The next episode will drop on 27 June.
Hosted on Acast. See acast.com/privacy for more information.
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In this episode of Brave New World, Evgeny talks to researcher and podcaster Rhonda Patrick.
The two discuss anti-ageing, with Patrick sharing her unique insights.
Together they cover:
How experiments on genetic pathways in worms got Patrick interested in the science of anti-ageing in humansThe impact of nutrition on our wellbeingWhich brands they trust most for supplements How to maintain adequate micronutrient levelsWhy nothing will ever be more effective than vigorous exercise The benefits of intermittent fasting The benefits of saunas and why we should use them more often. (With bonus guest Tamsin Lewis of Sunlighten.)If you enjoyed the episode, please leave us a review and follow.
The next episode will drop on 13 June.
Hosted on Acast. See acast.com/privacy for more information.
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In the first episode of our second season, Evgeny talks to professor Bill Irvine, an expert on stoicism whose books have democratised the ancient wisdom of Epictetus and Marcus Aurelius for a new generation which, he says, can benefit from it greatly. The two discuss:
· The unexpected success of his books and the âstoic renaissanceâ in the 21st century.
· What it actually means to be a stoic and how this helps us rise to different challenges.
· The core techniques of stoicism explored in his book The Stoic Challenge.
· Stoicism as an antidote to offence-taking.
· How stoicism helps us reframe setbacks as opportunities.
· What Seneca would have to say about free speech on college campuses.
If you enjoyed the episode, please hit follow and leave us a review.
Hosted on Acast. See acast.com/privacy for more information.
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Social psychologist Jonathan Haidtâs new book âThe Anxious Generationâ argues weâre overprotecting our children in real life, and underprotecting them online. In this special episode he tells Evgeny why he believes smartphones and social media have led to rises in anxiety, depression and suicide among young people, and why we have to âput the technology genie back in the bottleâ. They also discuss:
· The polarisation of politics and how it began before social media
· Why the evolution of social media has led to the return of âtribalismâ in society
· Why war between competing powers is âlikely to returnâ
· How ideas spread on US college campuses can go viral across the world
· What happens when you introduce fear into a liberal democracy
· How we âutterly failedâ with the introduction of AI
· Has social media ârewired our childrenâs brainsâ?
· Why parents have to let their kids go out again, and learn to fend for themselves
· Why he believes Mark Zuckerberg âcould and should have done moreâ to protect young people
The second season of Brave New World is coming soon, hit the follow button on your podcast provider so you donât miss an episode, and if you enjoyed this show please leave us a rating and review.
Hosted on Acast. See acast.com/privacy for more information.
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In the final episode of our first season, Evgeny talks to psychologist and researcher Bill Richards, whose book Sacred Knowledge: Psychedelics and Religious Experiences is considered a seminal work in the field and is now in its 10th edition. In this discussion, they talk about:
· Why science and spiritualism donât have to be separate from each other
· How he thinks transcendental experiences like those provoked by psychedelics are the "origin of most of the world's religions"
· His research into their benefits for those near the end of their lives
· Why is there a taboo against psychedelics research in health?
· What is our definition of ânormalâ and should we think about it differently.
· Billâs summer as an ordained minister, and his first psychedelic experience
· Why he doesnât think people should âpop psychedelicsâ just for fun.
Brave New World will return after the Easter break. Make sure youâre following the channel to get the first episode of season two as soon as it drops. And please do leave us a rating and review.
Hosted on Acast. See acast.com/privacy for more information.
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Evgeny meets Wim Hof to learn more about the Dutch athleteâs âMethodâ; a combination of breathing and cold-water immersion that he claims can have health and psychological benefits. Rita Ora also joins the show and talks about her own experience using Wimâs techniques as part of her wellness routines. And musician Marcus Flaherty tells us how he thinks the Method has helped him with some of the symptoms of MS. In this episode:
· Wim Hof reveals he developed âThe Methodâ to recover from the âemotional agonyâ following the death of his wife
· What happened the first time he entered ice cold water, and why did he want to do it again?
· How heâs trained his body to stay under the ice âfor up to seven minutesâ
· The scientific studies he says support his claims
· Rita Ora tells us about the surprise birthday visit she arranged with Wim for her husband Taika Waititi â and how he stayed in an ice bath for 30 minutes
· Her own use of both heat and cold as part of her wellness routine
· Her struggles with anxiety and panic attacks, and the techniques she uses to overcome them
· Why she wants Wim to release a playlist of music he gave her as an album.
If you enjoyed this episode of Brave New World, please leave us a rating and review. Hit your follow button to make sure you never miss an episode.
Hosted on Acast. See acast.com/privacy for more information.
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What is biohacking and are you already doing it without realising? Evgeny spends a day with the âworldâs fittest manâ, Ben Greenfield, to learn how exercise, diet and light contribute to wellness. He also meets actress and author Davinia Taylor, who tells him how biohacking helped her get over the alcoholism she developed at the height of her TV success in the 90s. In this episode we learn about:
· Ben Greenfieldâs journey from âfantasy novel reading, home-schooled kidâ to âAmericaâs Best Fitness Coachâ
· His six tips on how to improve your health
· How and why to safely expose your body to heat and cold
· The importance of his faith to his wellbeing and business
· The genetic reasons why diets can work for some but not for others
· Why Davinia Taylorâs declaring âwarâ on vegetable oil
· How sheâs turned her back on drink and drugs after years of addiction
· Her teaspoon of collagen tip to help with intermittent fasting
Next week, Rita Ora and Wim Hoff join the show to talk about the benefits of cold-water immersion and breathing exercises. Hit your follow button so you donât miss an episode.
Hosted on Acast. See acast.com/privacy for more information.
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Evgeny meets âanti-ageing poster boyâ Bryan Johnson, the entrepreneur whose âProject Blueprintâ aims to extend the human lifespan. He also talks to the 46-year-oldâs doctor Oliver Zolman, who details how theyâre approaching a controversial area of emerging science. In this episode we talk about:
· How they slowed Bryanâs speed of ageing âby the equivalent of 31 yearsâ
· Why Oliver Zolman thinks humans âcan live 25% longerâ
· Can we improve humans âat the speed of technologyâ?
· How the emergence of AI has made âdeath our only enemyâ
· Oliver Zolmanâs Six Principles for biohacking beginners
· How Bryan achieved â8 months of perfect sleepâ by designing his life around the need for it
· What Dr Zolman sees as the biggest health threat to western countries
· Is the resistance to longevity research more cultural than scientific?
If you enjoyed this episode please give Brave New World a rating and review. Hit the follow button on your podcast provider so you never miss an episode.
Hosted on Acast. See acast.com/privacy for more information.
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Evgeny Lebedev describes his experience at a psychedelic retreat in Costa Rica where he encountered Ayahuasca, a plant-based brew used by indigenous healers. Psychedelics researcher Professor David Nutt, psychologist Bill Richards and physician Gabor MatĂ© return to the show to explain whatâs happening to the mind when DMT is used and how some believe it can help with recovery from trauma. In this episode:
Evgeny reveals that Ayahuasca brought old fears home to roostDavid Nutt tells us about the history of psychedelic use, dating back to 5,000 BCBill Richards looks at the use of them by artists and writersGabor MatĂ© examines what Evgenyâs experience with Ayahuasca really says about his mental stateIf you enjoyed this episode of Brave New World please give us a rating and review. New episodes are released every Thursday. Hit the follow button to make sure you donât miss any.
Hosted on Acast. See acast.com/privacy for more information.
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