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Conversation with Prof. Scott L. Friedman [Mount Sinai School of Medicine, New York]
https://diagnosticdetectives.com/liver/friedman/
Causes, diagnosis, treatment of NAFLD and NASH. Genetic tests. Supplements and generic drugs for NASH. Liver cancer risk. Coffee helps liver health. On importance of having a good mentor.
00:00 Biography: Liver expert, Prof. Scott L. Friedman
01:33 What is Fatty Liver Disease [NAFLD]?
04:17 Non-obese patients with NAFLD.
05:29 Diagnostic tests for NAFLD.
06:31 Normal ALT, AST but bad NASH or NAFLD
07:40 FibroScan, MR Elastography to test for liver fibrosis
08:18 Can NAFLD be reversed?
09:34 How NASH differs from NAFLD?
10:16 What drives progression to NASH?
11:40 Genetic tests for risks of liver disease?
12:33 Microbiome and NAFLD / NASH?
14:09 Antibiotics in food lead to NAFLD / NASH.
16:06 ‘Auto-brewery syndrome’: gut makes alcohol?
17:56 Fecal microbiome transplantation for NASH?
20:29 Supplements and generics for NASH
20:48 Pharma is not interested in generics or supplements for NASH.
22:27 Hepatic Stellate Cells cause NAFLD / NASH?
28:30 Liver cancer and NASH / NAFLD?
32:03 How to personalize liver cancer screening in NASH?
34:27 Why no drugs approved for NASH?
38:28 Leading drug candidates for NASH therapy.
42:38 Repurposing generics for NASH therapy.
44:06 Statins for NASH and Heart risks?
45:00 Most NASH / NAFLD patients have NO symptoms
46:15 Coffee and liver health?
46:45 Coffee reduces risks of liver disease
48:13 Future of liver disease treatment.
49:56 Xenotransplantation for liver disease
51:15 Regeneration of liver: greatest mystery!
52:17 Questions of patients with liver disease.
53:51 ‘No symptoms but advanced liver disease’
54:12 How to improve liver health?
54:30 Weight loss is best therapy for NASH / NAFLD
55:22 Patients’ fear: no symptoms but bad liver disease?
55:54 Alcohol rarely causes NAFLD / NASH
56:42 ‘Mentorship is key to successful career’ - Prof. Friedman
#liver #NAFLD #NASH #exercise #livercancer #mentorship #cirrhosis #obesity #weightloss #EHNA #cancerdehigado #esteatohepatitis #Leber #FettigeLebererkrankung #Leberkrebs #Zirrhose #stéatohépatite #cancerdufoie #foie #stéatosehépatique
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Conversation notes:
1:00 Professor Tobias Welte, leading Lung Expert. Biography. Introduction.
5:27 COVID-19 vaccines: efficacy, safety, how long immunity lasts.
11:51 COVID-19 vaccine fear, young people vaccination, herd immunity.
16:29 Immune response difference between adenovirus and mRNA-based COVID-19 vaccines.
19:56 New COVID-19 virus mutations. Will vaccines continue to be effective?
24:03 Long-term safety of coronavirus vaccines. How long will it take to find side effects?
28:52 Decrease in COVID-19 antibody levels with time. Is protection still present?
32:46 Vaccination AFTER recovery from COVID-19? When to get a coronavirus vaccine.
36:47 Problems with clinical trials of COVID-19 treatments.
40:12 ICU treatment of severe COVID-19. Germany vs. USA.
44:36 Long-haul COVID-19 and rehabilitation after coronavirus. Reasons for optimism.
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https://diagnosticdetectives.com
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