Episodi
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Where to begin? It’s been a few weeks since you’ve heard from us – thank you so much for your amazing support and patience. As you may know, Hurricane Helene brought devastation to western North Carolina, eastern Tennessee, South Carolina, Georgia, and Florida. Genova Diagnostics is headquartered in the heart of Asheville, North Carolina. With that, it’s been a challenging few weeks. But the heroic efforts of many, and the resilient spirit of our team have us back up and running. Genova continues to support our local community- many of whom are still struggling and have lost everything. #WNCStrong
Today’s episode is a bit different than usual. It’s our story. Our lessons learned. Genova’s story of resilience when faced with a devastating, historic hurricane.
Additional Resources:
Genova Connect
Manna Food Bank
Eblen Charities
United Way Asheville
Beloved Asheville
Habitat for Humanity - AVL
Rural Organizing and Resilience
Subscribe, Rate, & Review The Lab Report
Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.
Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].
And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.
To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.
Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.
See omnystudio.com/listener for privacy information.
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Gastroesophageal reflux disease (GERD), or heartburn, is incredibly common as is the use of stomach acid suppressing medication. But what if there is far more to the story than stomach acid? There are many other factors to consider in a patient with heartburn. We are going to dive into the physiology of gastric acid, gastric hormonal signaling, and a slew of medications and foods that might be the real culprit. Are PPI’s over prescribed? Are we missing the picture? Tune in to find out.
In today’s episode, we tackle some burning questions about GERD and try to get to the root cause. Are acid suppressing medications always the answer? Perhaps the story is not that simple.
Today on The Lab Report:
3:45 Conventional medicine’s approach to GERD 6:30 The roll of the lower esophageal sphincter (LES) 8:15 Stomach acid and gastric hormonal signaling 13:20 Foods that affect the LES 14:15 PPI’s - controversy and weaning 18:00 Prescriptive meds, lifestyle, and the LES 19:50 Hiatal hernias 21:30 Question of the Day How does hypochlorhydria or PPI use affect Genova testing?Additional Resources:
Genova Connect **PROMO CODE TheLabReport20 for 20% off your purchase**
Subscribe, Rate, & Review The Lab Report
Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.
Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].
And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.
To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.
Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.
See omnystudio.com/listener for privacy information.
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Episodi mancanti?
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Occasionally, there are new and novel things introduced into the functional medicine and biohacker space that catch our attention. Lately, you might have heard a lot of people talking about the amazing health benefits of “nootropics,” but what are they? Coming from the name of the Greek word Nous (meaning “mind”), nootropics are medicines designed to improve cognitive function and protect the brain. Many of us could use a healthy dose of cognitive support to help us through our busy lives, but what is the truth about nootropics and where can we find them?
In today’s episode, we discuss the what, how, and why of nootropics. We explain what things are considered nootropics and how they work in the body. We also discuss what may be unexpected nootropic things you can do everyday that may not even be termed a nootropic. Listen for more information on how you can help get the most out of your cognition.
Today on The Lab Report:
3:30 There’s a lot of buzz about nootropics 4:30 Defining Terms: Nootropics 6:30 Michael rants on what is not a nootropic? 8:30 How do nootropics work in the body? 10:30 Vinpocetine 12:55 Huperzine A and brain energy 15:00 Astaxanthin - not just for flamingos 18:00 Nootropic herbs – aka “adaptogens” 22:10 Ginkgo biloba – a powerful nootropic 24:15 Are there side effects?Additional Resources:
Genova Connect **PROMO CODE TheLabReport20 for 20% off your purchase**
Subscribe, Rate, & Review The Lab Report
Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.
Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].
And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.
To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.
Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.
See omnystudio.com/listener for privacy information.
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Ok, we know what you’re thinking…. Artichokes? Really? Yes really. It may seem a bit out of left field, but you’d be surprised at the many health benefits from either eating artichokes or taking an extract supplement. As a vegetable, it contains fiber, vitamins, minerals, and antioxidants. Extracts made from artichoke leaves, stems, and roots have been used as nutraceutical agents to support the GI tract, liver, and cardiovascular system. But why?
In this episode, we peel back the layers of the artichoke – a very mysterious plant indeed. Is it possible to boost your health with artichoke leaf extract? Tune in to find out!
Today on The Lab Report:
3:25 Random artichoke topic – functional food 4:30 Jerusalem artichoke globe artichoke 6:00 Fruit, vegetable, and flowers - Extract vs. Whole food 8:15 Gut and liver health 10:35 Milk thistle vs. artichoke 12:30 Artichoke extract is antimicrobial 14:50 Powerful impact in IBD 18:00 Cardiovascular disease, neurodegenerative disease, cancer 20:00 Artichoke Game Time!!Additional Resources:
Genova Connect **PROMO CODE TheLabReport20 for 20% off your purchase**
Subscribe, Rate, & Review The Lab Report
Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.
Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].
And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.
To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.
Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.
See omnystudio.com/listener for privacy information.
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Mast Cell Activation Syndrome (MCAS) has become a hot topic in functional medicine. Mast cells are an integral part of the body’s immune system. They can be found in areas of exposure such as mucosal membranes, the lining of the GI tract, skin, and airways. Mast cells are responsible for storing important chemical mediators like histamine and others which help to instigate allergic responses. Mast cell disorders arise when there are too many mast cells, or they become hyperreactive. That being said, these conditions are often misunderstood, and diagnoses are sometimes misused.
In today’s episode, we focus on the role of mast cells and histamine in the immune response. We discuss the different mast cell activation disorders, how to diagnose them, and what you can do about it.
Today on The Lab Report:
3:05 Mast Cell Activation Diseases 5:15 What is a mast cell? Why do we care? 7:05 Symptoms of histamine release 8:40 Histamine intolerance vs. MCAS 11:11 Foods: High Histamine or Low Histamine? 14:25 Non-food related histamine associations 15:30 Diagnosing and treating MCAS 18:00 Question of the Day What Genova profiles can help parse out histamine intolerance v. MCAS?Additional Resources:
IgE Food Antibodies Profile
IgE Inhalants - Allergy Profile
IgE Mold - Allergy Profile
Methylation Panel
Subscribe, Rate, & Review The Lab Report
Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.
Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].
And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.
To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly, visit Genova Connect.
Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.
See omnystudio.com/listener for privacy information.
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The gut microbiome harbors trillions of commensal organisms which play a central role in our health. This community is sometimes referred to as our hidden metabolic organ due to its immense impact. Our diet and lifestyle play an important role in feeding the microbiome and keeping the colonies in balance. Should we be concerned if any one bacterial colony overgrows?
Today we discuss the commensal bacteria Desulfovibrio. Since this genus of bacteria can reduce sulfate and make hydrogen sulfide gas, overgrowth can have clinical implications. Listen in for more information on why you should care and what you can do about it.
Today on The Lab Report:
2:45 Why Desulfovibrio? Define Some Terms! Commensalism 5:20 Desulfovibrio – what does it do? Why that name? 7:10 Hydrogen sulfide gas – symptoms and its role 9:00 IBD and Desulfovibrio 10:00 Can you have DV and be healthy? 11:00 Other correlations – neurodegenerative disease, autism, metabolic syndrome, cancer 13:45 Pre- and pro-biotics as treatment adjuncts and the Naturopathic Therapeutic Order 17:09 Fructo-oligosaccharides and prebiotics to feed the microbiome – it depends 19:30 Question of the Day Does the GI Effects measure other sulfur-reducing bacteria? 21:15 Evolving research – Desulfovibrio and GLP-1 hormonesAdditional Resources:
Genova Connect **PROMO CODE TheLabReport20 for 20% off your purchase**
GI Effects Stool Profile
Subscribe, Rate, & Review The Lab Report
Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.
Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].
And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.
To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.
Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.
See omnystudio.com/listener for privacy information.
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There are a lot of terms bantered about in the biohacker and longevity space. With that, you’ve likely heard of mTOR – mechanistic (mammalian) target of rapamycin. But what exactly is it? mTOR is a key regulator in your body’s metabolic and growth processes. It integrates various signals, including nutrients and growth factors, to control processes like protein synthesis, autophagy, and lipid metabolism. Because it regulates growth, dysregulation of mTOR has been implicated in various diseases, including cancer.
In today’s episode, we simplify the science behind mTOR – mechanistic target of rapamycin. This crucial enzyme may be the key to unlocking groundbreaking advancements in wellness, anti-aging, disease prevention, and health optimization.
Today on The Lab Report:
3:00 mTOR – Why are we even covering this topic? 4:40 What is it? Muscle growth vs. autophagy 6:25 Why is it called mTOR? 9:00 Highly conserved and in every cell, every organ 10:30 mTORC1 and mTORC2 11:25 Influences and sensors – it’s more than leucine 14:25 Dysregulation of mTOR – does protein cause cancer? 17:30 Should people take rapamycin for longevity? 20:20 Question of the Day Where does mTOR work in muscle protein synthesis?Additional Resources:
Genova Connect **PROMO CODE TheLabReport20 for 20% off your purchase**
Subscribe, Rate, & Review The Lab Report
Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.
Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].
And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.
To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.
Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.
See omnystudio.com/listener for privacy information.
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Multi-omics is the layering of genetic information (genomics) with laboratory biomarker results (metabolomics) to understand the root cause of disease and risk. This educational series focuses on genetic variants in specific enzymes and explains how to evaluate the systemic effects.
Today’s episode revolves around the enzyme cystathionine-beta-synthase (CBS). This enzyme is important for homocysteine metabolism, sitting at a branch point between two important cycles: methylation and transsulfuration. The action of this enzyme is important for balancing the critical functions of methylation with the creation of glutathione and energy. Listen to understand why this enzyme is important and what a genetic variant in CBS might mean for you and your patients.
Today on The Lab Report:
2:20 Reminder of what we mean by multi-omics 4:50 Introducing the CBS enzyme and the sink drain metaphor 7:40 The genetics of CBS – the silent mutation – and its potential effects 12:40 Better Know A Biomarker: Cystathionine! 16:20 Activators and inhibitors of CBS and its effects on other biomarkers 18:55 Question of the Day: Does a CBS SNP cause elevated ammonia levels? 21:40 Evaluating surrounding biomarkers and how do you treat this SNP?Additional Resources:
Methylation Panel
Genova Connect **PROMO CODE TheLabReport20 for 20% off your purchase**
Subscribe, Rate, & Review The Lab Report
Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.
Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].
And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.
To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.
Disclaimer: The content and information shared in The Lab Report is for educational purposes only and show not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.
See omnystudio.com/listener for privacy information.
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Many of us have heard of glutathione and understand that it is a powerful antioxidant – but why? What is it? How does it work? Understanding the mechanisms of this crucial molecule can help you fully grasp its importance. Oxidative stress and the damage of free radicals underlie the aging process and many chronic conditions. There’s no greater tool to combat oxidative stress than glutathione.
In today’s episode, we break down the science of glutathione and redox reactions. You will learn how glutathione works, how to support optimal levels, and how it connects to the methylation cycle!
Today on The Lab Report:
3:00 Is there more to Glutathione than you think? 4:20 Glutathione as a tripeptide 5:40 Redox reactions & the role of glutathione 8:30 Rate-limiting steps – cysteine, NAC 9:55 Holding!! Maybe it’s glycine 12:30 Factors needed for production 13:05 Measuring levels – total, reduced, oxidized 16:40 Clinical associations 18:30 Supplementing to support glutathione 22:00 Question of the Day Is glutathione related to methylation?Additional Resources:
Genova Connect **PROMO CODE** TheLabReport20 for 20% off your purchase
NutrEval
Methylation Panel
Subscribe, Rate, & Review The Lab Report
Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.
Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].
And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.
To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.
Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.
See omnystudio.com/listener for privacy information.
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Creatine is a powerhouse supplement known for enhancing muscle strength, endurance, and recovery. By boosting ATP production, it fuels muscles during intense workouts, leading to greater gains and faster progress. Beyond its skeletal muscle benefits, creatine supports cognitive function, fertility, sight, hearing, and just about every process in the body.
Today we discuss creatine and its many health benefits. Whether you're an athlete striving for peak performance or someone simply looking to improve overall health and vitality, consider fueling your potential with creatine.
Today on The Lab Report:
3:50 Creatine and methylation 6:00 How does the body make creatine? 7:55 Creatine and skeletal muscle 10:40 Brain health, cognition, sight, and hearing 13:05 Creatine and Fertility 14:15 How much do we make; how much do we need? 17:30 Confusion around kidney function and creatine supplementation 19:15 Side effects and hydrationAdditional Resources:
Genova Connect **PROMO CODE TheLabReport20 for 20% off your purchase**
Subscribe, Rate, & Review The Lab Report
Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.
Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].
And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.
To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.
Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.
See omnystudio.com/listener for privacy information.
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Dr. Bill Rawls was a practicing OB/GYN physician for decades before his health began to suffer and he was faced with the limitations of modern medicine. Embarking on his own health journey, he dove headfirst into holistic and herbal therapies and found ultimate wellness. Dr. Rawls now teaches and writes extensively about the power of herbal medicine. He’s written several books including Suffered Long Enough, Unlocking Lyme, and his latest book The Cellular Wellness Solution. Dr. Rawls even started his own herbal supplement and wellness company called Vital Plan.
In today’s episode, Dr. Bill Rawls discusses his new book, The Cellular Wellness Solution, a fresh take on the critical role our cells play in unlocking wellness and supporting health. He champions the power of herbal medicine and explains why you should too.
Today on The Lab Report:
4:00 Meet Dr. Rawls and hear his journey to herbal medicine 8:45 The Cellular Wellness Solution – 5 underlying cellular stressors 14:05 Microbial stress, chronic disease, and cancer? 21:10 Germ theory vs. Terrain theory 25:50 Difference between pharmaceutical drugs and herbs 32:15 Isolated constituents vs. whole herbs, adaptogens 33:20 Daily-use herbs, adaptogens, antimicrobials, anti-inflammatories 40:40 Current-day farming, primitive foraging, and the effects on our plants 44:30 Vital Plan and cautionary tales regarding supplement quality 50:20 The FireballAdditional Resources:
Dr. Bill Rawls' website
The Cellular Wellness Solution
Genova Connect **PROMO CODE TheLabReport20 for 20% off**
Subscribe, Rate, & Review The Lab Report
Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.
Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].
And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.
To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.
Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.
See omnystudio.com/listener for privacy information.
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In the world of athletic performance, there are plenty of health experts. But none like Ian Craig. Ian Craig takes a holistic and very personalized approach. With his joint academic backgrounds in exercise physiology and nutritional therapy, and a long successful career as a British middle-distance runner and coach, he’s been developing the concept of integrative sports nutrition for the past 20 years.
Today we speak with Ian Craig who lays out the case for personalized and holistic care when it comes to optimizing athletic performance. Through his Centre for Integrative Sports Nutrition in Scotland, he’s been a leading voice worldwide bridging the gap between conventional sports nutrition and a functional approach to health.
Today on The Lab Report:
5:00 Meet the amazing Ian Craig 6:55 Balancing life load and athletics 11:10 Runners vs. other athletes 14:30 Integrative Sports Nutrition Pyramid 21:00 Convincing athletes to rest! 24:35 Ergogenic aids 28:05 The line between ergogenic aids and PEDs 30:25 Trade-offs with ergogenic aids 32:45 Upcoming textbook and CISN training 37:15 The FireballAdditional Resources:
Centre for Integrative Sports Nutrition (CISN)
Health Feeds Performance Podcast
Genova Connect **PROMO CODE TheLabReport for 20% off your purchase**
Subscribe, Rate, & Review The Lab Report
Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.
Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].
And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.
To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.
Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.
See omnystudio.com/listener for privacy information.
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Artificial intelligence and machine learning is being leveraged in every facet of society to improve efficiency and drive innovation. Healthcare is no different. Language models, algorithms, machine learning, and more are being developed and used to help with education, behavior change, administrative tasks, predictive risk assessments, and at times, disease diagnosis.
In today’s episode, we discuss areas where the healthcare industry is harnessing artificial intelligence. With such powerful technology at our fingertips, it is always important to take a pause to debate the exciting capabilities but also its limitations and biases.
Today on The Lab Report:
5:25 Artificial intelligence is everywhere 8:36 Patient education, oversight, and bias 9:50 Benefit in preventing human error 10:40 Diagnostic models and risk assessments 12:20 Bias and mistakes on both sides – where’s the liability? 16:10 Patient confidentiality concerns 17:30 Wearable devices and behavioral change 21:00 Personalization, empathy, and the human element 23:00 Generative AI, novel insights, and sound data 24:55 Considering all traditions of medicineAdditional Resources:
Genova Connect **PROMO CODE TheLabReport for 20% off your purchase**
Subscribe, Rate, & Review The Lab Report
Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.
Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].
And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.
To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.
Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.
See omnystudio.com/listener for privacy information.
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Is it possible to be drunk without drinking alcohol? Actually, yes. There is a condition called auto-brewery syndrome whereby an imbalance in your gut microbiome can ferment carbohydrates to create alcohol. Blood alcohol levels can get surprisingly high. Though this condition is thought to be rare, it might just be underdiagnosed. Patients are dealing with legal ramifications, social stigmas, and disbelief by friends, family, and physicians.
Today we introduce the topic of auto-brewery syndrome to raise awareness that your gut microbiome can produce alcohol. We discuss how it occurs, how to diagnose it, and some strategies to treat it.
Today on The Lab Report:
3:10 What is auto-brewery syndrome? 5:30 Causes and clinical associations 9:45 SIBO/SIFO – should we be checking alcohol levels? 10:50 Chronic tolerance and long-term alcohol effects 12:20 How to diagnose ABS 14:30 Treatment strategies 17:00 Is it as rare as we think? Is there a spectrum? 18:12 Question of the Day What patterns might we see on GI Effects and NutrEval?Additional Resources:
Genova Connect **PROMO CODE TheLabReport20 for 20% off your purchase**
Auto-Brewery Syndrome Advocacy and Research
Subscribe, Rate, & Review The Lab Report
Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.
Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].
And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.
To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.
Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.
See omnystudio.com/listener for privacy information.
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Food labels can be very confusing. In fact, many of us completely ignore them. If you look at the ingredients in many processed foods, you’ve probably tried to pronounce some of the chemical compounds listed in the ingredients. The food industry adds chemicals to food to either enhance flavor and color, or to preserve shelf life. There are thousands of accepted food additives and some may have important health implications.
In today’s episode, we discuss just a few additives you might want to keep an eye out for next time you go to the grocery store.
Today on The Lab Report:
3:20 MSG – monosodium glutamate 6:40 Nitrites and nitrates 9:55 The “Name that Food” game 12:45 Sulfites are everywhere 13:55 Maraschino cherries are polarizing? 15:20 Sulfites as a top food allergen 16:55 Food colorings, FD&C, lakes, and blue rats 21:25 Artificial vs. natural flavoringAdditional Resources:
Genova Connect **PROMO CODE TheLabReport for 20% off your purchase**
Subscribe, Rate, & Review The Lab Report
Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.
Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].
And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.
To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.
Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.
See omnystudio.com/listener for privacy information.
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Shakira Niazi is the founder of Basil Seed Works – an organic basil seed product line featuring the superfood ZenBasil. As a refugee from war-torn Afghanistan who was later raised and educated in the US, Shakira’s path to becoming an entrepreneur is remarkable. Although she’s known for her work with Vita Water – helping to solve the world water crisis and providing water points to poor villages around the world, her current focus is to bring basil seeds from the Far East to the Western world. Basil seeds are a natural source of fiber, omega-3 fatty acids, vitamins, minerals, and antioxidants.
In today’s show, Shakira Niazi tells us her inspiring story - from childhood refugee to being featured in Times Square. We also discuss the amazing health benefits of basil seeds and why they are the new superfood!
Today on The Lab Report:
5:30 Meet Shakira Niazi and hear her amazing story 10:30 Changing courses through the pandemic 20:40 Health benefits of basil seeds 26:40 Hydrating and using basil seeds 28:45 ZenBasil vs. other basil seeds 30:45 Where to find ZenBasil 32:00 The FireballAdditional Resources:
ZenBasil
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Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.
Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].
And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.
To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.
Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.
See omnystudio.com/listener for privacy information.
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Dr. Stephanie Venn-Watson dedicated her life to public health and veterinary epidemiology. In studying dolphins, she discovered the first essential fatty acid to be found in over 90 years – C15:0 (pentadecanoic acid). Dr. Stephanie’s discovery and further research on C15:0 has uncovered some amazing cellular health benefits and significant potential for disease prevention. With this knowledge, Dr. Stephanie pivoted and founded fatty15 - a company that produces the world’s first, and only science-backed, patented C15:0 supplement.
In today’s episode, we speak with Dr. Stephanie Venn-Watson about her latest research into the newly discovered essential fatty acid C15:0 and how supplementation with fatty15 could be a game-changer for cellular health.
Today on The Lab Report:
4:45 Stephanie Venn-Watson on veterinary epidemiology and dolphins 10:15 Pentadecanoic acid (C15:0), dolphins, and disease 12:20 Food sources for C15:0 15:35 Essential fatty acid criteria 18:45 Cellular stability and pentadecanoic acid 21:10 Red blood cell membranes and testing 24:10 Iron and ferroptosis 28:00 Measuring cell fragility 31:30 Ferroptosis and inflammatory cascades 34:05 Fatty15 supplementation 39:10 The FireballAdditional Resources:
fatty15
Genova Connect **PROMO CODE TheLabReport for 20% off your purchase**
Subscribe, Rate, & Review The Lab Report
Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.
Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].
And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.
To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.
Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.
See omnystudio.com/listener for privacy information.
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Methylation is a very important enzymatic reaction responsible for so many crucial metabolic processes. In a previous episode, we introduced the topic of methylation and the basics of this biochemical reaction. However, there are many subtle nuances to consider when assessing whether a patient’s methylation cycle is out of balance.
Today, we dive a bit deeper into the biochemistry of methylation and peel back the layers to show how some of the specific biomarkers and backup pathways contribute to imbalance. And, what does that mean clinically? It may help to review our prior episode or use Genova’s Methylation Pathway Handout to follow along.
Today on The Lab Report:
2:50 Quick review of the methylation cycle 4:45 The important relationship between choline and betaine 7:05 Logical Speculation: Why is the betaine: choline ratio associated with disease risk? 9:35 Dimethylglycine (DMG) 11:15 Sarcosine and the ‘SAM disposal chute’ 14:20 Glycine: What does it do? 16:55 Transsulfuration and glutathione 21:00 The multi-omics of the methylation panel 22:25 Question of the Day: What is the stability of measuring SAM and SAH?Additional Resources:
Genova's Methylation Panel
Dr. Michael Chapman's Methylation Webinar
Genova Connect **PROMO CODE TheLabReport for 20% off your purchase**
Subscribe, Rate, & Review The Lab Report
Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.
Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].
And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.
To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.
Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.
See omnystudio.com/listener for privacy information.
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We are honored to welcome Dr. Casey Means back to the show. She is not only a passionate advocate for metabolic health, but also a voice of reason amidst a broken healthcare system, a profound champion spreading the message of connectedness and fearlessness, and lastly a dear friend. Dr. Means’ new book “Good Energy – The Surprising Connection Between Metabolism and Limitless Health” is available now anywhere books are sold.
In this episode, we talk to Dr. Casey Means about her new book “Good Energy” which outlines how to connect the dots in healthcare, the critical importance of metabolic health, and practical tips to change your life and create your own GOOD ENERGY.
Today on The Lab Report:
3:10 The Amazing Dr. Casey Means on connection vs. siloes in medicine 8:45 Economics of the current healthcare model and outdated thinking 12:15 Longevity and biohacking – where have we lost our way? 19:55 Fear of death, control, and transcending the fear mindset 23:20 Fixing incentive structures of the healthcare system & food and farm industries 33:10 Practical tips and eating for GOOD ENERGY 40:55 Overcoming behavior change obstacles – listen to your body! 44:00 ROI in eating healthy whole foods 45:35 Life is miraculous, live in awe- not fear 48:05 The FireballAdditional Resources:
Get your copy of Good Energy today!
Casey’s Newsletter sign-up: https://www.caseymeans.com/newsletter
Casey’s Social Media Platforms:
Instagram: https://www.instagram.com/drcaseyskitchen/
Twitter: https://twitter.com/CaseyMeansMD
TikTok: https://www.tiktok.com/@caseymeansmd
YouTube: https://www.youtube.com/@CaseyMeansMD
LinkedIn: https://www.linkedin.com/in/casey-means-md/
Subscribe, Rate, & Review The Lab Report
Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.
Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].
And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.
To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.
Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.
See omnystudio.com/listener for privacy information.
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The word ‘methylation’ has become somewhat of a buzz word in functional and personalized medicine. We’ve mentioned it several times throughout many episodes of The Lab Report – hard to avoid since it’s involved in just about every biological process.
In today’s episode, we finally hit the topic of methylation head on and dive into the methylation cycle itself. What is it? Why should you care? Although biochemistry can be intimidating, listen as we simplify and demystify the steps involved. You may find it helpful to refer to a Methylation Pathway Chart while listening to this one!
Today on The Lab Report:
2:00 What is methylation and why is it clinically important 5:30 Jumping into the biochemistry – metaphors to the rescue! 11:35 Homocysteine 14:00 The main pathway versus back up pathway 19:33 Transsulfuration 22:30 Multi-omics and the methylation cycle 27:50 Question of the Day “What does it mean if homocysteine is low?”Additional Resources:
Genova's Methylation Panel
Dr. Michael Chapman's Methylation Webinar
Genova Connect **PROMO CODE TheLabReport20 for 20% off your purchase**
Subscribe, Rate, & Review The Lab Report
Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.
Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].
And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.
To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.
Disclaimer: The content and information shared in The Lab Report is for educational purposes only and show not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.
See omnystudio.com/listener for privacy information.
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