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  • Optimal Medical Therapy in Peripheral Artery Disease

    Guest: Stan Henkin, M.D.

    Host: Malcolm R. Bell, M.D.

    Atherosclerosis of peripheral (ie, non-coronary) arteries, also known as peripheral artery disease (PAD), affects more than 8 million Americans. Unfortunately, compared to coronary artery disease (CAD), PAD is often underdiagnosed and undertreated. In this podcast, experts discuss optimal medical therapy in patients with PAD.

    Topics Discussed:

    What is peripheral artery disease? What are the most common symptoms of PAD?You diagnose PAD. What pharmacologic and non-pharmacologic therapies do you consider?How do you follow-up a patient with PAD?When should a patient be referred to a vascular specialist?

    Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

    LinkedIn: Mayo Clinic Cardiovascular Services

    Cardiovascular Education App:The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!

    No CME credit offered for this episode.

    Podcast episode transcript found here.

  • Dyspnea After Pulmonary Embolism: Optimal Medical Therapy in Peripheral Vascular Disease

    Guest: Stan Henkin, M.D.

    Host: Malcolm R. Bell, M.D.

    Historically, majority of clinical and research focus has been on acute management of pulmonary embolism (PE). However, long-standing functional impairment after PE is common, occurring in up to 50% of individuals with history of PE. This is termed post-PE syndrome – an underrecognized, underdiagnosed, and undertreated entity. In this podcast, experts discuss epidemiology, pathophysiology, diagnosis, and treatment of post-PE syndrome.

    Topics Discussed:

    What is Post-PE syndrome? How common is it?What is your suggested work-up of patient who presents with dyspnea after PE?When should a patient be referred to a tertiary/expert center?

    Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

    LinkedIn: Mayo Clinic Cardiovascular Services

    Cardiovascular Education App:The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!

    No CME credit offered for this episode.

    Podcast episode transcript found here.

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  • MINOCA: Myocardial Infarction with Non-Obstructive Coronary Arteries

    Guest: Claire E. Raphael, M.B.B.S., Ph.D.

    Host: Sharonne Hayes, M.D.

    MINOCA is a myocardial infarction with no obstructive coronary artery disease. This podcast will discuss the underlying causes of MINOCA, how to and who to investigate and discuss contemporary management strategies.

    Topics Discussed:

    What is MINOCA?What testing should I consider in patients with MINOCAHow are these patients treated?

    Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

    LinkedIn: Mayo Clinic Cardiovascular Services

    Cardiovascular Education App:The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!

    No CME credit offered for this episode.

    Podcast episode transcript found here.

  • An AI-ECG Algorithm for Left Ventricular Diastolic Dysfunction

    Guest: Jae Oh, M.D.

    Host: Anthony H. Kashou, M.D.

    Diastolic function assessment is crucial in diagnosing, managing, and predicting outcomes in various cardiac conditions. It provides insight into heart health, particularly in diagnosing heart failure. Shortness of breath, a common patient complaint, often indicates elevated diastolic filling pressure if linked to a cardiac condition. Echocardiography is the primary method for assessing diastolic function, but it is operator-dependent and not always available. In contrast, ECGs are standardized and widely accessible. Although subtle changes in ECGs are not easily detectable by the human eye, artificial intelligence can identify specific conditions reflected in the ECG. By training an AI model with labeled ECGs based on diastolic function determined through echocardiography, researchers achieved high accuracy in detecting diastolic dysfunction. AI-enhanced ECGs can significantly impact the identification of both asymptomatic and symptomatic cardiac conditions, potentially streamlining diagnostic strategies and reducing costs. Future developments may enable patients to monitor their heart health using simple wearable devices, enhancing the management of heart failure and other conditions.

    Topics Discussed:

    Your special clinical academic interest is echocardiography. Why are you interested in ECG AI in diastolic function?What is diastolic function and why is it important to assess diastolic function in clinical practice?Why did you decide to create AI-ECG for diastolic function assessment?What did you find and how do you envision AI ECG for diastolic function be used in clinical practice?

    Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

    LinkedIn: Mayo Clinic Cardiovascular Services

    Cardiovascular Education App:The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!

    No CME credit offered for this episode.

    Podcast episode transcript found here.

  • Novel Mitral Therapies

    Guest: Arman Arghami, M.D., M.P.H.

    Guest: Mayra Guerrero, M.D.

    Host: Kyle Klarich, M.D.

    And the end of this podcast, the listener should understand how to identify new minimally invasive procedures to treat patients with mitral valve disease, delineate the difference between minimally invasive surgery versus percutaneous transcatheter interventions for mitral valve disease, and recognize when to refer patients for mitral valve interventions.

    Topics Discussed:

    What are the minimally invasive intervention options to treat patient with mitral valve disease?Which are the patients who benefit from less invasive procedures?How and when to refer a patient for mitral valve intervention?If a patient had prior mitral valve surgery (repair or replacement) and has recurrent mitral valve disease, is redo mitral surgery always needed? Or can a patient with prior surgery be treated with a transcatheter mitral valve repair or replacement, avoiding the need for repeat surgery?

    Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

    LinkedIn: Mayo Clinic Cardiovascular Services

    Cardiovascular Education App:The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!

    No CME credit offered for this episode.

    Podcast episode transcript found here.

  • Myocarditis - Presentation and Recent Advances

    Guest: Drew Rosenbaum, M.D.

    Host: Sharonne Hayes, M.D.

    Through this podcast, listeners should understand how myocarditis manifests, both in the hospitalized patients as well as in clinical practice in order to facilitate recognition of the disease to initiate the appropriate work and achieve a diagnosis. The treatment strategies depend highly on the underlying condition. Although current strategies for treatment are evolving, a conceptual framework for which patients may benefit from anti-inflammatory therapies and which may not is critical to appropriate select therapies for patients affected by myocarditis.

    Topics Discussed:

    What is the spectrum of manifestations of myocarditis?How do you diagnose myocarditis?How is myocarditis treated and what is on the horizon for myocarditis?

    Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

    LinkedIn: Mayo Clinic Cardiovascular Services

    Cardiovascular Education App:The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!

    No CME credit offered for this episode.

    Podcast episode transcript found here.

  • Valve Disease in Pregnancy

    Guest: Katie Young, M.D.

    Hosts: Sharonne Hayes, M.D.

    In this podcast we will review the medical management of native valvular heart disease in pregnancy, highlighting the importance of specialized care through a Pregnancy Heart Team approach.

    Topics Discussed:

    What are the anticipated physiologic changes of pregnancy and their importance to individuals with valvular heart disease?What are the highest risk valvular lesions for pregnancy?Can you discuss general medical management recommendations for those with stenotic lesions in pregnancy?Are regurgitant valve lesions always well tolerated in pregnancy?

    Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

    LinkedIn: Mayo Clinic Cardiovascular Services

    Cardiovascular Education App:The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!

    No CME credit offered for this episode.

    Podcast episode transcript found here.

  • Cardioneural ablation for atrial fibrillation: Indications and rationale

    Guest: Guru G. Kowlgi, M.B.B.S.

    Host: Anthony H. Kashou, M.D.

    The learners will get an overview of how high a vagal tone can contribute to atrial fibrillation. In addition, they will gain an understanding of cardioneural ablation, which is a promising new catheter ablation treatment option for these patients.

    Topics Discussed

    How does high vagal tone contribute to atrial fibrillationWhat subset of patients with atrial fibrillation can benefit from cardioneural ablationWhat studies have been performed in this field, and what does the future of Afib ablation look like?

    Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

    LinkedIn: Mayo Clinic Cardiovascular Services

    Cardiovascular Education App:The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!

    No CME credit offered for this episode.

    Podcast episode transcript found here.

  • Interventional Management of Acute Pulmonary Embolism

    Guest: Arashk Motiei, M.D.

    Hosts: Sharonne Hayes, M.D.

    We will discuss the can temporary interventional management of patients with massive acute pulmonary embolism and intermediate high-risk acute pulmonary embolism.

    Topics Discussed:

    Who are the patients with pulmonary embolism who need to be considered for interventional treatment?What do we know about risk assessment in patients with intermediate high-risk pulmonary embolism? What are the types of interventional treatments that are currently available?Systemic thrombolysis is often used for the management of acute pulmonary embolism. Is there any role for this with the availability of interventional approaches?

    Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

    LinkedIn: Mayo Clinic Cardiovascular Services

    Cardiovascular Education App:The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!

    No CME credit offered for this episode.

    Podcast episode transcript found here.

  • Cardiac Amyloidosis: No Longer Rare and Untreatable!

    Guest: Omar F. Abou Ezzeddine, M.D., M.S.

    Hosts: Malcolm R. Bell, M.D.

    Transthyretin amyloid cardiomyopathy (ATTR-CM), once considered rare, is more prevalent than previously thought. Diagnosing ATTR-CM is particularly important because there are now highly effective, specific therapies for ATTR-CM. In this podcast, we will provide a contemporary review of the diagnostic and therapeutic approach to patients with ATTR-CM in the current era.

    Topics Discussed:

    When to suspect the disease & who to screen for ATTR-CM?How to diagnose and prognosticate ATTR-CM in the current era?Provide an overview of current and emerging therapies for managing ATTR-CM.

    Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

    LinkedIn: Mayo Clinic Cardiovascular Services

    Cardiovascular Education App:The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!

    No CME credit offered for this episode.

    Podcast episode transcript found here.

  • IV Agents to Improve Echo Images, Value, and Safe Administration

    Guest: Jeremy Thaden, M.D.

    Guest: Mays Ali, M.D.

    Hosts: Kyle Klarich, M.D.

    In this podcast we will review current and evolving indications for UEA use in the clinical and research setting. They will review Mayo Clinic’s practice for UEA administration, commonly encountered UEA side-effects, and appropriate management strategies.

    Topics Discussed:

    What are the indications to use ultrasound enhancement agent (UEA) in your clinical practice and how are they useful?Who administers the UEA in your clinical practice?Are there potential side effects of UEA that one should be aware of?What is the appropriate management of side effects and how does the echo lab manage them when they arise?

    Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

    LinkedIn: Mayo Clinic Cardiovascular Services

    Cardiovascular Education App:The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!

    No CME credit offered for this episode.

    Podcast episode transcript found here.

  • Cardioneural Ablation - A Promising Treatment Strategy for Refractory Vasovagal Syncope

    Guest: Guru G. Kowlgi, M.B.B.S.

    Host: Anthony H. Kashou, M.D.

    The learners will get an overview of how to diagnose and manage vasovagal syncope. In addition, they will gain an understanding of cardioneural ablation, which is a promising new catheter ablation treatment option for these patients.

    Topics Discussed

    What is vasovagal syncope (VVS)?How do we diagnose vasovagal syncope?What are some treatment strategies for VVS (including a discussion on cardioneural ablation and the use of pacemakers)?

    Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

    LinkedIn: Mayo Clinic Cardiovascular Services

    Cardiovascular Education App:The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!

    No CME credit offered for this episode.

    Podcast episode transcript found here.

  • Pre-Pregnancy Risk Assessment for CV Patients

    Guest: Katie A. Young, M.D.

    Hosts: Malcolm R. Bell, M.D.

    In this podcast we will review the importance of specialized care in Cardiovascular Obstetrics and the role of the Pregnancy Heart Team in pregnancy risk assessment and pre-conception counseling.

    Topics Discussed:

    With maternal mortality rates being 2 fold higher in the US compared to other developed countries, how can we work to decrease maternal mortality rates?How can we best estimate maternal cardiovascular and obstetric risks?Who should be counseled against pursuing pregnancy?What other testing do we consider as important components of the pre-conception evaluation?

    Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

    LinkedIn: Mayo Clinic Cardiovascular Services

    Cardiovascular Education App:The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!

    No CME credit offered for this episode.

    Podcast episode transcript found here.

  • Cardio-oncology: What is the Big Picture, What Drugs to Use, and What Tests to Follow

    Guest: Chadi Ayoub, M.B.B.S., Ph.D.

    Hosts: Sharonne N. Hayes, M.D.

    In this podcast, we will describe more frequent cardiotoxic effects associated with cancer therapies. Identify imaging modalities that can be used to detect and evaluate cardiotoxicity and common adverse cardiac events associated with immune checkpoint inhibitors. As well review currently available treatment options to address cardiovascular toxicity.

    Topics Discussed:

    What are the main chemotherapy agents that cause cardiotoxicity?What testing can be done to screen for and diagnose cardiotoxicity, and when should it be done?What can be done to address cardio-toxicity when it arises? What treatments are available, and how can we minimize interruptions to cancer therapy?Immune checkpoint inhibitor therapy has revolutionized the care of some cancers, what cardiac toxicities are there and what have we learned about them from study of our patients?How does radiation therapy affect the heart, and what can be done to minimize this?

    Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

    LinkedIn: Mayo Clinic Cardiovascular Services

    Cardiovascular Education App:The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!

    No CME credit offered for this episode.

    Podcast episode transcript found here.

  • Clinical Quantification of Myocardial Blood Flow Using PET

    Guest: Panithaya Chareonthaitawee, M.D.

    Hosts: Malcolm R. Bell, M.D.

    In this podcast, we will describe the clinical applications of PET MBF quantitation and discuss the strengths and limitations of PET MBF quantification.

    Topics Discussed:

    Why has PET myocardial perfusion imaging seen such growth?You mentioned the ability of PET to measure myocardial blood flow. Why is this crucial?So, should myocardial blood flow measurement be standard in all PET MPI studies? Does it require special equipment or extra time?Are there specific values to remember for PET flow quantification?

    Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

    LinkedIn: Mayo Clinic Cardiovascular Services

    Cardiovascular Education App:The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!

    No CME credit offered for this episode.

    Podcast episode transcript found here.

  • 3D Visualization of the Heart in Immersive Technology Like Mixed Reality

    Guest: Dr. Klaudia Proniewska

    Host: Anthony H. Kashou, M.D.

    The most commonly applied way of teaching students the foundations of human anatomy and physiology involves textbooks and lectures. This method of transmitting knowledge causes difficulties for students, especially in the context of three-dimensional imaging of organ structures, and as a consequence, translates into difficulties with imagining them. Even with the rapid uptake of knowledge dissemination provided by online materials, including courses and webinars, there is a clear need for learning programs featuring first-hand immersive experiences tailored to individual study paces. In my research, I present an approach to enhance a classical study program by combining multi-modality data and representing them in a Mixed Reality (MR)-based environment. The advantages of the proposed approach have been proven by the conducted investigation of the relationship between heart anatomy, its electrophysiological characteristics, and resulting wave morphology on the electrocardiogram (ECG). Another part of the research focuses on the role of the anatomy of the heart, e.g., the sinoatrial node, in ECG formation, while the MR-based visualization of combined imaging data with non-invasive CineECG (by Peter van Dam) imaging demonstrates the educational application of these advanced technologies for teaching cardiac anatomy and ECG correlations.

    Topics Discussed

    Can you explain why three-dimensional structures are important to teach electrophysiology of the heart?How does the electrocardiogram (ECG) relate to heart anatomy, and why is this relationship fundamental in understanding cardiac electrophysiology? Give an example.Have you implemented any innovative teaching methods or technologies to enhance the learning experience in cardiac anatomy and electrophysiology? If so, can you describe their impact?In your experience, what are the most effective ways to convey complex 3D structures and dynamic processes in cardiac anatomy and electrophysiology to students or professionals?

    Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

    LinkedIn: Mayo Clinic Cardiovascular Services

    Cardiovascular Education App:The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!

    No CME credit offered for this episode.

    Podcast episode transcript found here.

  • Marfan Surgery

    Guest: Alberto Pochettino, M.D.

    Hosts: Paul A. Friedman, M.D.

    Marfan syndrome is a genetic abnormality where the fibrillin protein is abnormal. That affects all collagen structures within a given individual. Phenotypic features involve ocular abnormalities such as lens dislocation and a higher risk of retinal detachment, as well as diffuse musculoskeletal abnormalities such as scoliosis, joints abnormalities, and the diffuse hyper extension of all joints. By far the most life-threatening feature in Marfan syndrome is aortic abnormality.

    Topics Discussed:

    Which patients with Marfan syndrome should be evaluated for aortic disease?Do all Marfan patients develop aortic aneurysm?What other cardiovascular abnormalities are noted in Marfan syndrome?What preventive operations are available, and what are the expected outcomes from such operations?If a Marfan patient develops a type B dissection what is the appropriate management?

    Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

    LinkedIn: Mayo Clinic Cardiovascular Services

    Cardiovascular Education App:The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!

    No CME credit offered for this episode.

    Podcast episode transcript found here.

  • Hypertensive Disorders of Pregnancy and CV Risk

    Guest: Thais D. Coutinho, M.D.

    Hosts: Paul A. Friedman, M.D.

    Hypertensive disorders of pregnancy are common and are associated with a significant increase in the risk of future cardiovascular diseases. Despite the well-established statistics, this increase in risk is not well recognized by patients or healthcare providers. The objectives of this podcast are to highlight the cardiovascular risks associated with hypertensive disorders of pregnancy, describe strategies to identify and mitigate this risk, and identify knowledge gaps and research opportunities in the field.

    Topics Discussed:

    Can you explain what are the hypertensive disorders of pregnancy?After a woman is diagnosed with a hypertensive disorder of pregnancy, what are the cardiovascular consequences?How should clinicians approach a patient with history of hypertensive disorder of pregnancy, in order to understand and minimize their cardiovascular risk?Tell us about some of your research in this field.What are the major needs for new research and clinical translation in this field?

    Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

    LinkedIn: Mayo Clinic Cardiovascular Services

    Cardiovascular Education App:The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!

    No CME credit offered for this episode.

    Podcast episode transcript found here.

  • Genomics in Inflammatory Cardiomyopathies

    Guest: Naveen L. Pereira, M.D.

    Hosts: Kyle W. Klarich, M.D

    Patients with heart failure and ventricular arrhythmias can have inflammatory heart disease such as myocarditis or sarcoidosis. The diagnosis is typically made by imaging studies including cardiac MRI and PET scans. However, it is critical to performed genetic testing in such patients given that genetic cardiomyopathy can often present as an inflammatory heart disease phenotype which may have important prognostic and therapeutic implications.

    Topics Discussed:

    How do inflammatory cardiomyopathies typically present? When do you suspect inflammation as a cause of cardiomyopathy?How is the diagnosis typically made and is there a role for endomyocardial biopsy?Why is genetic testing important once a diagnosis of an inflammatory cardiomyopathy is made?If the genetic test is positive in these patients what the clinical implications?

    Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

    LinkedIn: Mayo Clinic Cardiovascular Services

    Cardiovascular Education App:The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!

    No CME credit offered for this episode.

    Podcast episode transcript found here.

  • Understanding ECG Waveforms: Normal vs. Abnormal

    Guest: Dr. Peter van Dam

    Host: Anthony H. Kashou, M.D.

    The ECG interpretation is majorly driven by event detection, i.e. QRS onset and end, QT time, P wave etc. From these we can determine the normal heart rhythm, and some performance measures, like heart rate etc. The ECG waveforms, however, are much less understood. This is a pity, as ECG waveforms, provide instantaneous information on the electrophysiological and structural function of the heart. In this respect it is interesting to know if there is something like a normal ECG waveform or normal PathECG (CineECG). This latter technique is a vector-based method to estimate the electrical position of a moving vector within the heart. Similar normal distributions can be created to compare to the normal ECGs.

    Topics DiscussedHow can we define a normal ECG waveform? (ECGs from healthy normal people for different age groups, I used about 6000 normal ECGs, correction for heart rate by resampling to standard QT time (400 ms for instance, these ECGs can be used to create a distribution of amplitudes and derived signals (CineECG) to compare an ECG too)What is needed for an accurate waveform comparison? (Good baseline correction, not filtering, but baseline correction) What is the onset and end of the P-wave, QRS and T wave?)Are normal ECGs waveforms different from abnormal ECG waveforms? (Of course they overlap, describe left bundle branch block, or ischemia, with long QRS or deviating ST segment )Did you use this method to classify ECGs as normal or abnormal? (results from our study (manuscript in preparation) that any QRST sequence in an ECG can be classified as abnormal with an accuracy (AUC) of more than 81%. In our study population 15% of the patients had only atrial related abnormal ECGS)

    Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

    LinkedIn: Mayo Clinic Cardiovascular Services

    Cardiovascular Education App:The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today!

    No CME credit offered for this episode.

    Podcast episode transcript found here.