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00:46 The role of skull bone marrow in ageing
During ageing, bone marrow in the skull becomes an increasingly important site of blood-cell production. This is in stark contrast to most bones where the ability of marrow to make blood and immune cells declines. Studies in mice and humans showed that ageing results in skull bone-marrow expanding, and in mice this marrow was more resistant to inflammation and other hallmarks of ageing. The team behind the work hope by understanding this process better it may be possible to help organs become more resistant to ageing.
Research Article: Koh et al.
08:56 Research HighlightsElderly big brown bats show remarkable resistance to age-related hearing loss, and why search-engine algorithms may not be the main driver steering people towards misinformation.
Research Highlight: No hearing aids needed: batsâ ears stay keen well into old age
Research Highlight: Donât blame search engines for sending users to unreliable sites
11:38 How to make lead a useful material to date the Solar SystemResearchers have overcome a major hurdle preventing the radioactive isotope lead-205 from being used as a âclockâ to date the age of the Solar System. 205Pb is made in some stars and thanks to its half life of around 17 million years has been proposed as a potential way to date ancient astronomical processes. However, exactly how much 205Pb can escape a star were unclear, limiting its dating potential. Now, researchers have mimicked the conditions seen in stars to pin down how much 205Pb can escape into space, paving the way for its use as a clock.
Research Article: Leckenby et al.
19:51 Briefing ChatHow millions of Android smartphones were used to map the Earthâs ionosphere, and the ethical implications of a virologist who treated her own cancer.
Nature: Google uses millions of smartphones to map the ionosphere
Nature: This scientist treated her own cancer with viruses she grew in the lab
Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
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Samantha Harvey's Booker Prize shortlisted novel Orbital is set inside an International Space Station-like vessel circling 250 miles above Earth. It looks at a day-in-the-life of the crew, investigating the contrasts they experience during the 16 orbits they make around the planet, crossing continents, oceans and the line separating night and day.
On the latest episode of Nature hits the books, Samantha joins us to discuss why the ISS is a rich setting for fiction, the challenges of putting yourself in the shoes of an astronaut, and how distance can give new perspectives on global issues like climate change.
Orbital Samantha Harvey Vintage (2024)
Music supplied by Airae/Epidemic Sound
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00:46 Mitochondria divide their labour to help cells thrive
Researchers have uncovered that mitochondria divide into two distinct forms when cells are starved, a finding that could help explain how some cancers thrive in hostile conditions. Mitochondria are cellular powerhouses, creating energy and vital metabolic molecules, but how they are able to do this when resources are limited has been a mystery. It turns out that in nutrient-poor situations, mitochondria split into two separate types, one which concentrates on energy production, the other on producing essential cellular building blocks. Together these allow cells to make everything they need. The team showed that this also happens in certain cancer cells, which may help them survive and grow under hostile conditions in the body.
Research Article: Ryu et al.
News and Views: Division of labour: mitochondria split to meet energy demands
Video: A new kind of mitochondrion
07:53 Research HighlightsA tidy genome may explain naked mole ratsâ long lifespans, and why the midlife crisis may not be as ubiquitous as previously thought.
Research Highlight: Naked mole rats vanquish genetic ghosts â and achieve long life
Research Highlight: The midlife crisis is not universal
10:41 A smashing way to snapshot an atomic nucleiâs shapePhysicists have revealed a new technique to image the shape of atomic nuclei â by smashing them together. The nucleus of an atom doesnât really resemble what is shown in textbooks â they actually come in a variety of shapes, which drive an elementâs behaviour. Current methods essentially take a long-exposure photo of an atomâs nucleus, which doesnât capture the subtle variations in how the protons and neutrons arrange themselves. The new method overcomes this by colliding nuclei together and then using information on the resulting debris to reconstruct the shape of the nucleus. The researchers hope that this technique can help physicists resolve many more mysteries about atomic nuclei.
Research Article: STAR Collaboration
News: Scientists worked out the shapes of atomic nuclei â by exploding them
19:51 Briefing ChatAnalysing the genome of an ancient clone forest has revealed it could be up to 80,000 years old, and how putting limits on the famous infinite monkey theorem means they probably wouldnât churn out Shakespeare before the end of the Universe.
Nature: The worldâs oldest tree? Genetic analysis traces evolution of iconic Pando forest
The Guardian: Universe would die before monkey with keyboard writes Shakespeare, study finds
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This series was originally broadcast in 2020.
Science and politics are not easy bedfellows - "Stick to the science" is a three part series which aims to find out why.
In the third and final episode we try to get to the bottom of how journalists, communicators and policymakers influence how science is perceived. We discuss the danger of politicization and ask the question - can science be part of the political narrative without compromising its values?
This episode was produced by Nick PetriÄ Howe, with editing from Noah Baker and Benjamin Thompson. It featured: Deborah Blum, Bruce Lewenstein, Dan Sarewitz, Hannah Schmid-Petri, Shobita Parthasarathy, and Beth Simone Noveck.
Further Reading
The great fish pain debate
Politicization of mask wearing
Masks work
Donald Trump used a quote from Anthony Fauci to falsely suggest Fauci approved of his actions in the pandemic
Comparing Norway and Sweden in their coronavirus combating actions
Beth Simone Noveck argues for more open and transparent governance
Solving Public Problems, by Beth Simone Noveck
Smart Citizens, Smarter State: The Technologies of Expertise and the Future of Governing, by Beth Simone Noveck
The Received Wisdom Podcast, with Shobita Parthasarathy
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This series was originally broadcast in 2020.
Science and politics are not easy bedfellows - "Stick to the science" is a three part series which aims to find out why.
In this episode we're asking how politics shapes the life of a working scientist. Be it through funding agendas, cultural lobbies or personal bias, there's a myriad of ways in which politics can shape the game; influencing the direction and quality of research, But what does this mean for the objective ideals of science?
This episode was produced by Nick PetriÄ Howe, with editing from Noah Baker and Benjamin Thompson. it featured contributions from many people, including: Mayana Zatz, Shobita Parthasarathy, Michael Erard, Peg AtKisson, Susannah Gal, Allen Rostron, Mark Rosenberg, and Alice Bell.
Further Reading
Brazilâs budget cuts threaten more than 80,000 science scholarships
Move to reallocate funds from scientific institutions in SĂŁo Paulo
Backlash to âShrimps on a treadmillâ
Explanation of the Dickey Amendment
After over 20 years the CDC can now fund gun violence research
Spirometer use ârace-correctionâ software
Black researchers less likely to get funding from the National Institutes of Health in the US
Black researchers may get less funding from the National Institutes of Health due to topic choice
Black researchers fill fewer academic roles in the UK
Clinical trials use mostly white participants
The Received Wisdom Podcast, with Shobita Parthasarathy
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This series was originally broadcast in 2020.
Science and politics are not easy bedfellows - "Stick to the science" is a three part series which aims to find out why.
In this episode we delve into the past, and uncover the complicated relationship between science, politics and power. Along the way, we come up against some pretty big questions: what is science? Should science be apolitical? And where does Nature fit in?
This episode was produced by Nick PetriÄ Howe, with editing from Noah Baker and Benjamin Thompson. it featured contributions from many researchers, including: Shobita Parthasarathy, Alice Bell, Dan Sarewitz, Anna Jay, Melinda Baldwin, Magdelena Skipper, Steven Shapin, David Edgerton, Deborah Blum, Bruce Lewenstein and Chiara Ambrosio. Quotes from social media were read by: Shamini Bundell, Flora Graham, Dan Fox, Edie Edmundson and Bredan Maher. And excerpts from Nature were read by Jen Musgreave.
Further Reading
History of Education in the UK
Natureâs History
Natureâs Mission statement
Nature editorial on covering politics
Making âNatureâ, by Melinda Baldwin
Never Pure: Historical Studies of Science as if It Was Produced by People with Bodies, Situated in Time, Space, Culture, and Society, and Struggling for Credibility and Authority, by Steven Shapin
David Edgertonâs writing on the history of science and politics in the Guardian
The received wisdom podcast with Shobita Parthasarathy
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00:48 Rebuilding mental health after the floods
Researchers have been investigating the best ways to help people deal with trauma in the wake of a climate disaster. In April and May devastating floods surged across Rio Grande do Sul in the South of Brazil, affecting two million people and killing hundreds. As people try to put their lives back together scientists have been conducting surveys and investigating how to make sure that any mental health issues donât become persistent. We hear from some of the affected people and researchers in the region.
This story was supported by the Pulitzer Center.
News Feature: How to recover when a climate disaster destroys your city
13:48 Research HighlightsA new way to make ultra-heavy elements, and how some plankton swim by blowing up like a balloon.
Research Highlight: Atomic smash-ups hold promise of record-breaking elements
Research Highlight: This plankton balloons in size to soar upwards through the water
16:54 What are your thoughts on the US election?Nature has conducted a poll of its readers to get a sense of what is on researchersâ minds in the run up to the US election. Overwhelmingly, the survey respondents identified as researchers and reported that they supported Vice President Harris (86%). Many also voiced concerns about a possible victory for former President Trump, saying that they would consider changing where they would live if he wins. Reporter Jeff Tollefson tells us more about the results and what the election means for US science.
News: The US election is monumental for science, say Nature readers â hereâs why
27:07 Briefing ChatThe possible benefits of âpoo milkshakesâ for newborns, and how Tardigrades can withstand incredibly high levels of radiation.
Nature: âPoo milkshakeâ boosts the microbiome of c-section babies
Nature: New species of tardigrade reveals secrets of radiation-resisting powers
Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
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By the end of 2024 up to two billion people will have gone to the polls, in a pivotal year of elections around the globe. This is giving political scientists the chance to dive into each election in detail but also to compare the differing voting systems involved.
They hope understanding the advantages and drawbacks of the systems will help highlight whether some are more likely to promote democratic resilience or to stave off corrosive partisanship.
This is an audio version of our Feature: Which is the fairest electoral system? Mega-election year sparks debate
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00:48 The hidden cities of Uzbekistan
Researchers have uncovered the scale of two ancient cities buried high in the mountains of Uzbekistan. The cities were thought to be there, but their extent was unknown, so the team used drone-mounted LiDAR equipment to reveal what was hidden beneath the ground. The survey surprised researchers by showing one of the cities was six times bigger than expected. The two cities, called Tashbulak and Tugunbulak, were nestled in the heart of Central Asiaâs medieval Silk Road, suggesting that highland areas played an important role in trade of the era.
Research Article: Frachetti et al.
Video: Uncovering a lost mountain metropolis
09:32 Research HighlightsHow children'sâ movements resemble water vapour, and why coastal waters may be a lot dirtier than we thought.
Research Highlight: Kids in the classroom flow like water vapour
Research Highlight: Sewage lurks in coastal waters â often unnoticed by widely used test
12:06 Watermarking AI-generated textA team at Google Deepmind has demonstrated a way to add a digital watermark to AI-generated text that can be detected by computers. As AI-generated content becomes more pervasive, there are fears that it will be impossible to tell it apart from content made by humans. To tackle this, the new method subtly biases the word choices made by a Large Language Model in a statistically detectable pattern. Despite the changes to word choice, a test of 20 million live chat interactions revealed that users did not notice a drop in quality compared to unwatermarked text.
Research Article: Dathathri et al.
News: DeepMind deploys invisible âwatermarkâ on AI-written text
22:38 Briefing ChatWhat one researcher found after repeatedly scanning her own brain to see how it responded to birth-control pills, and how high-altitude tree planting could offer refuge to an imperilled butterfly species.
Nature: How does the brain react to birth control? A researcher scanned herself 75 times to find out
Nature: Mexican forest ârelocatedâ in attempt to save iconic monarch butterflies
Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
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In this episode:
00:46 An unusual Îł-ray producing microquasarA type of binary-system known as a microquasar has been found to be firing out Îł-rays at high energy-levels, which may make it a candidate to be a long-theorized natural particle-accelerator known as a PeVatron. These objects are thought to be a source of galactic cosmic rays, the origins of which are currently a mystery.
Understanding how this microquasar works could also help researchers learn more about full-sized quasars â monstrous objects centred around supermassive black holes, which are too distant to study easily.
Research Article: Alfaro et al.
News and Views: High-altitude particle detector spots a second Galactic microquasar
09:27 Research HighlightsThe comb jellies caught fusing their bodies, and an ancient burial site reveals that Classical accounts of Scythian culture appear to be true.
Research Highlight: Two comb jellies fuse their bodies and then act as one
Research Highlight: Evidence of dead people posed on dead horses found in ancient tomb
12:08 A âsmartâ insulin-molecule that could lower hypoglycaemia riskResearchers have developed a modified insulin-molecule that varies its level of activity depending on blood-glucose levels. Itâs hoped that this âsmartâ insulin could one day help those with diabetes regulate their blood sugar more easily.
Many people with diabetes rely on regular insulin injections, but because blood-sugar levels can be difficult to predict it can be hard to select the correct dose. This can lead to hypoglycaemia â a life-threateningly low level of glucose. To overcome this, a team created a modified form of insulin with a switch that activates the molecule when glucose levels are high, and deactivates it when levels are low. This insulin-molecule was effective at maintaining correct blood glucose in animal models, and may eventually help lessen diabetes-related complications in humans.
Research Article: Hoeg-Jensen et al.
News and Views: Smart insulin switches itself off in response to low blood sugar
20:33 Briefing ChatAncient DNA confirms that infamous lions hunted humans and a variety of game, and a new technique can sequence a cellâs DNA and pinpoint its proteins, without cracking it open.
Nature: Famed lionsâ full diet revealed by DNA â and humans were among their prey
Nature: âPhenomenalâ tool sequences DNA and tracks proteins â without cracking cells open
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00:55 Graphene Tongue
Researchers have developed a graphene âtongueâ that uses AI to tell the subtle differences between drinks. Graphene has long been sought after as a chemical sensor, but tiny variations between devices have meant that it couldnât be used very reliably. The team behind the âtongueâ got around this problem by training an AI to tell the difference between similar liquids regardless of variations between graphene devices. They hope that their work shows that itâs possible to use âimperfectâ chemical sensors to get accurate readings and that the âtongueâ will be able to help detect problems with food.
Research Article: Pannone et al.
09:22 Research HighlightsA 3D-printed optical microscope that can image biological samples with ultrahigh resolution, and how newly-hatched sea turtles dig their way up to the beach.
Research Highlight: A âSwiss army knifeâ microscope that doesnât break the bank
Research Highlight: Baby sea turtles âswimâ up from buried nests to the open air
11:32 How migrating salmon move nutrients and contaminants at a continental scaleStudies of migrating Pacific salmon have revealed that these animals transport thousands of tonnes of nutrients and kilograms of contaminants from the ocean to freshwater ecosystems. Itâs been known that as the fish return to their freshwater spawning grounds from the sea they bring with them both nutrients and contaminants, but the impact of each has largely been studied separately. A new study combines datasets to estimate that over 40 years, the levels of nutrients these fish carry have increased at a proportionally higher rate than the contaminants, but the toxins could nevertheless be present at concerning levels to the animals that eat them.
Research Article: Brandt et al.
News and Views: Salmonâs moveable feast of nutrients with a side order of contaminants
23:19 Nobel NewsFlora Graham from the Nature Briefing joins us to talk about the winners of this yearâs science Nobel Prizes.
News: Medicine Nobel awarded for gene-regulating âmicroRNAsâ
News: Physics Nobel scooped by machine-learning pioneers
News: Chemistry Nobel goes to developers of AlphaFold AI that predicts protein structures
Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
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00:46 Physicists spot new types of high-energy radiation in thunderstorms
Physicists have identified new forms of Îł-ray radiation created inside thunderclouds, and shown that levels of Îł-ray production are much higher on Earth than previously thought.
Scientists already knew about two types of Îł-ray phenomena in thunderclouds â glows that last as long as a minute and high-intensity flashes that come and go in only a few millionths of a second. Now, researchers have identified that these both occur more frequently than expected, and that previously undetected Îł-ray types exist, including flickering flashes that share characteristics of the other two types of radiation.
The researchers hope that understanding more about these mysterious phenomena could help explain what initiates lightning, which often follows these Îł-ray events.
Research Article: Ăstgaard et al.
Research Article: Marisaldi et al.
Nature: Mysterious form of high-energy radiation spotted in thunderstorms
10:00 Research HighlightsAncient arrowheads reveal that Europe's oldest battle likely featured warriors from far afield, and why the dwarf planet Ceresâs frozen ocean has deep impurities.
Research Highlight: Bronze Age clash was Europeâs oldest known interregional battle
Research Highlight: A dwarf planet has dirty depths, model suggests
12:09 A complete wiring diagram of the fruit fly brainResearchers have published the most complete wiring diagram, or âconnectomeâ of the fruit flyâs brain, which includes nearly 140,000 neurons and 54.5 million connections between nerve cells.
The map, made from the brain of a single female fruit fly (Drosophila melanogaster), reveals over 8,400 neuron types in the brain, and has enabled scientists to learn more about the brain and how it controls aspects of fruit fly behaviour.
The FlyWire connectome: neuronal wiring diagram of a complete fly brain
Nature: Largest brain map ever reveals fruit fly's neurons in exquisite detail
22:16 Briefing ChatHow researchers created an elusive single-electron bond between carbon atoms, and why bigger chatbots get over-confident when answering questions.
Nature: Carbon bond that uses only one electron seen for first time: âIt will be in the textbooksâ
Nature: Bigger AI chatbots more inclined to spew nonsense â and people don't always realize
Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
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The world's fastest supercomputer, known as Frontier, is located at the Leadership Computing Facility at Oak Ridge National Laboratory in Tennessee. This machine churns through data at record speed, outpacing 100,000 laptops working simultaneously.
With nearly 50,000 processors, Frontier was designed to push the bounds of human knowledge. It's being used to create open-source large language models to compete with commercial AI systems, simulate proteins for drug development, help improve aeroplane engine design, and more.
This is an audio version of our Feature: A day in the life of the worldâs fastest supercomputer
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In this episode:
00:46 Unravelling why children with Downâs syndrome are at a higher risk of leukaemiaChildren with Downâs syndrome have a 150-fold increased risk of developing leukaemia than those without the condition. Now, an in-depth investigation has revealed that changes to genome structures in fetal liver stem-cells appear to be playing a key role in this increase.
Downâs syndrome is characterised by cells having an extra copy of chromosome 21. The team behind this work saw that in liver stem-cells â one of the main places blood is produced in a growing fetus â this extra copy results in changes in how DNA is packaged in a nucleus, opening up areas that are prone to mutation, including those known to be important in leukaemia development.
The researchers hope their work will be an important step in understanding and reducing this risk in children with Downâs syndrome.
Research Article: Marderstein et al.
News and Views: Childhood leukaemia in Downâs syndrome primed by blood-cell bias
11:47 Research HighlightsHow taking pints of beer off the table lowers alcohol consumption, and a small lizardâs âscuba gearâ helps it stay submerged.
Research Highlight: A small fix to cut beer intake: downsize the pint
Research Highlight: This âscuba divingâ lizard has a self-made air supply
14:12 Briefing ChatHow tiny crustaceans use âsmellâ to find their home cave, and how atomic bomb X-rays could deflect an asteroid away from a deadly Earth impact.
Science: In the dark ocean, these tiny creatures can smell their way home
Nature: Scientists successfully ânuke asteroidâ â in a lab mock-up
Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
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In this episode:
00:45 The biggest black hole jets ever seenAstronomers have spotted a pair of enormous jets emanating from a supermassive black hole with a combined length of 23 million light years â the biggest ever discovered. Jets are formed when matter is ionized and flung out of a black hole, creating enormous and powerful structures in space. Thought to be unstable, physicists had theorized there was a limit to how large these jets could be, but the new discovery far exceeds this, suggesting there may be more of these monstrous jets yet to be discovered.
Research Article: Oei et al.
09:44 Research HighlightsThe knitted fabrics designed to protect wearers from mosquito bites, and the role that islands play in fostering language diversity.
Research Highlight: Plagued by mosquitoes? Try some bite-blocking fabrics
Research Highlight: Islands are rich with languages spoken nowhere else
12:26 A sustainable, one-step method for alloy productionMaking metal alloys is typically a multi-step process that creates huge amounts of emissions. Now, a team demonstrates a way to create these materials in a single step, which they hope could significantly reduce the environmental burdens associated with their production. In a lab demonstration, they use their technique to create an alloy of nickel and iron called invar â a widely-used material that has a high carbon-footprint. The team show evidence that their method can produce invar to a quality that rivals that of conventional manufacturing, and suggest their technique is scalable to create alloys at an industrial scale.
Research article: Wei et al.
25:29 Briefing ChatHow AI-predicted protein structures have helped chart the evolution of a group of viruses, and the neurons that cause monkeys to âchokeâ under pressure.
Nature News: Where did viruses come from? AlphaFold and other AIs are finding answers
Nature News: Why do we crumble under pressure? Science has the answer
Subscribe to the Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
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In this episode:
00:45 What ancient DNA has revealed about Rapa Nuiâs pastAncient DNA analysis has further demonstrated that the people of Rapa Nui did not cause their own population collapse, further refuting a controversial but popular claim. Rapa Nui, also known as Easter island, is famous for its giant Moai statues and the contested idea that the people mismanaged their natural resources leading to âecological suicideâ. Genomes sequenced from the remains of 15 ancient islanders showed no evidence of a sudden population crash, substantiating other research challenging the collapse idea.
Research Article: Moreno-Mayar et al.
News and Views: Rapa Nuiâs population history rewritten using ancient DNA
News article: Famed Pacific islandâs population 'crash' debunked by ancient DNA
17:03 Research HighlightsThe extinct bat-eating fish that bit off more than they could chew, and how manatee dung shapes an Amazonian ecosystem.
Research Highlight: Ancient fish dined on bats â or died trying
Research Highlight: The Amazonâs gargantuan gardeners: manatees
19:29 A macabre parasite of adult fruit fliesDespite being a hugely-studied model organism, it seems that thereâs still more to find out about the fruit fly Drosophila melanogaster, as researchers have discovered a new species of parasitoid wasp that infects the species. Unlike other parasitic wasps, this one lays its eggs in adult flies, with the developing larva devouring its host from the inside. The miniscule wasp was discovered by chance in an infected fruit fly collected in a Mississippi backyard and analysis suggests that despite having never been previously identified, it is widespread across parts of North America.
Research article: Moore et al.
32:04 Briefing ChatHow a dye that helps to give Doritos their orange hue can turn mouse tissues transparent, and an effective way to engage with climate-science sceptics.
Nature News: Transparent mice made with light-absorbing dye reveal organs at work
Nature News: How to change peopleâs minds about climate change: what the science says
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The often repeated claim that "80% of the world's biodiversity is found in the territories of Indigenous Peoples" appears widely in policy documents and reports, yet appears to have sprung out of nowhere. According to a group of researchers, including those from Indigenous groups, this baseless statistic could be undermining the conservation efforts of the Indigenous People it's meant to support and prevent further work to really understand how best to conserve biodiversity.
Two of the authors joined us to discuss how this statistic gained traction, the harm it could cause, and how better to support the work of Indigenous Peoples.
Read more in a Comment article from the authors: No basis for claim that 80% of biodiversity is found in Indigenous territories
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In this episode:
00:45 Why a 'nuclear clock' is now within researchersâ reachResearchers have made a big step towards the creation of the long theorized nuclear clock, by getting the most accurate measurement of the frequency of light required to push thorium nuclei into a higher energy state. Such a timekeeper would differ from the best current clocks as their âtickâ corresponds to the energy transitions of protons and neutrons, rather than electrons. Nuclear clocks have the potential to be more robust and accurate than current systems, and could offer researchers new insights into fundamental forces present within atomic nuclei.
Research Article: Zhang et al.
News and Views: Countdown to a nuclear clock
Nature News: âNuclear clockâ breakthrough paves the way for super-precise timekeeping
Editorial: Progress on nuclear clocks shows the benefits of escaping from scientific silos
10:10 Research HighlightsThe star that got partially shredded by a supermassive black hole, not just once, but twice, and how heatwaves could mangle bumblebeesâ sense of smell.
Research Highlight: This unlucky star got mangled by a black hole â twice
Research Highlight: Bumblebeesâ sense of smell canât take the heat
12:11 How engineered immune cells could help limit damage after spinal injuryBy harnessing T cells to fine-tune the inflammation response, researchers have limited the damage caused by spinal injury in mice, an approach they hope might one day translate into a human therapy. Following injury to the central nervous system, immune cells rush to the scene, resulting in a complex array of effects, both good and bad. In this work researchers have identified the specific kind of T cells that amass at the site, and used them to create an immunotherapy that helps the mice recover more quickly from injuries by slowing damage to neurons.
Research article: Gao et al.
20:36 Briefing ChatHow unprecedented floods in Brazil have helped and hindered paleontologists, and the âAI scientistâ that does everything from literature review through to manuscript writing, to an extent.
Nature News: The race to save fossils exposed by Brazilâs record-setting floods
Nature News: Researchers built an âAI Scientistâ â what can it do?
Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.
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The 'file-drawer problem', where findings with null or negative results gather dust and are left unpublished, is well known in science. There has been an overriding perception that studies with positive or significant findings are more important, but this bias can have real-world implications, skewing perceptions of drug efficacies, for example.
Multiple efforts to get negative results published have been put forward or attempted, with some researchers saying that the incentive structures in academia, and the âpublish or perishâ culture, need to be overturned in order to end this bias.
This is an audio version of our Feature: So you got a null result. Will anyone publish it?
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In this episode:
00:31 Chatbots makes racist judgements on the basis of dialectResearch has shown that large language models, including those that power chatbots such as ChatGPT, make racist judgements on the basis of usersâ dialect. If asked to describe a person, many AI systems responded with racist stereotypes when presented with text written in African American English â a dialect spoken by millions of people in the United States that is associated with the descendants of enslaved African Americans â compared with text written in Standardized American English. The findings show that such models harbour covert racism, even when they do not display overt racism, and that conventional fixes to try and address biases in these models had no effect on this issue.
Research Article: Hoffman et al.
News and Views: LLMs produce racist output when prompted in African American English
Nature News: Chatbot AI makes racist judgements on the basis of dialect
07:01 How ancient engineers built a megalithic structureThe 6,000-year-old Dolmen of Menga is a marvel of ancient engineering. New research reveals new insights into the structure and the technical abilities of the Neolithic builders who constructed it. The work shows that a setup of counterweights and ramps may have been used to correctly position the massive sandstone blocks that make up walls of the structure, which were each tilted at precise, millimetre-scale angles. The researchers suggest that this construction shows that the Neolithic people who built the dolmen had a working understanding of physics, geometry, geology and architectural principles.
Nature News: Stone Age builders had engineering savvy, finds study of 6000-year-old monument
12:28 Spider makes fireflies flash as baitOrb-weaving spiders (Araneus ventricosus) use ensnared male Absocondita terminalis fireflies to trick more insects into their web. A bite from the spider causes the flashing pattern of the trapped firefly to shift to one resembling a female looking to mate, leading others into an ambush. Exactly how this system works is unclear, but researchers say it is a rare example of a predator altering the behaviour of its prey to catch others.
Science: Spiders force male fireflies to flash like femalesâluring more males to their death
16:35 The physics of paper cutsBy combining experiments and theoretical work, a team has unraveled the mystery of why only certain types of paper can cut into human skin. Their work shows that paper that is too thin will buckle without cutting, while paper thatâs too thick will distribute force over a relatively large area without inflicting damage. The research suggests that the sweet spot for slicing is paper with around 65 micrometres in thickness, which includes the kind used to print certain high-profile journalsâŠ
Research Highlight: What Science and Nature are good for: causing paper cuts
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