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  • The gene variant APOE4 is finally giving up some of its secrets, how putting dead trees underground could make carbon sequestration cheap and scalable, and the latest in our series of books on an optimistic future First up this week, Staff Writer and Editor Jocelyn Kaiser joins host Sarah Crespi to discuss APOE4, a gene linked with a higher risk of Alzheimer’s disease. They talk about new research into why APOE4 might be a good target for preventing or treating this dreaded neurodegenerative disease. Next, Ning Zeng, a professor in the Department of Atmospheric & Oceanic Science and at the Earth System Science Interdisciplinary Center at the University of Maryland, joins the show to discuss an unusual approach to carbon sequestration and a very old piece of wood. He talks about how an unearthed 3000-year-old log that has held on to most of its carbon is pretty good proof that we can efficiently put carbon underground at low cost by burying trees. Finally, we have the latest in our series of books on a future to look forward to. Books host Angela Saini talks with Peter Coveney and Roger Highfield, the two authors of the book Virtual You: How Building Your Digital Twin Will Revolutionize Medicine and Change Your Life. This week’s episode was produced with help from Podigy. About the Science PodcastEpisode page: https://www.science.org/doi/10.1126/science.z8oerdq Authors: Sarah Crespi; Jocelyn Kaiser; Angela SainiLearn more about your ad choices. Visit megaphone.fm/adchoices

  • First up this week, a preview of a NASA mission to Jupiter’s icy moon Europa. Science journalist Robin Andrews joins host Sarah Crespi to talk about the Clipper mission and what it could reveal about the habitability of the world that lies beneath Europa’s chaotic, icy surface.
     
    Next, what does it feel like to be a rat? This week Science has a special issue on rats, focusing on their contributions to science, their history as invasives and disease carriers, and more. But Inbal Ben-Ami Bartal, a professor in the School of Psychological Sciences and the Sagol School of Neuroscience at Tel Aviv University, is here to talk about their capacity for empathy and other positive emotions.
     
    In a sponsored segment from the Science/AAAS Custom Publishing Office, Erika Berg, director and senior editor of custom publishing, interviews University of Manchester professor Sarah Haigh about the past, present, and future of graphene. This segment is sponsored by Zeiss.
     
    This week’s episode was produced with help from Podigy.
     
    About the Science Podcast
     
    Authors: Sarah Crespi; Robin Andrews

    Episode page: https://www.science.org/doi/10.1126/science.zapddvc
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  • Why don’t we know what is happening with hail? It’s extremely destructive and costs billions of dollars in property damage every year. We aren’t great at predicting hailstorms and don’t know much about how climate change will affect them, but scientists are working to change that. News Intern Hannah Richter joins host Sarah Crespi to discuss deploying new technologies in this long-neglected area of research.
    Next on the show, ultrasound—it’s not just for looking inside the body anymore. Meaghan O’Reilly is a senior scientist in physical sciences at the Sunnybrook Research Institute, an associate professor of medical biophysics at the University of Toronto, and is the Canada Research Chair in biomedical ultrasound. She talks about how researchers are using focused sound waves to disrupt tumors, change the permeability of the blood-brain barrier, stimulate the immune system, and more.
    This week’s episode was produced with help from Podigy.
    About the Science Podcast
    Authors: Sarah Crespi; Hannah Richter
    Episode page: https://www.science.org/doi/10.1126/science.zm3x6zq 
    About the Science Podcast: https://www.science.org/content/page/about-science-podcast
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  • The latest in our series on global equity in science, and how better memory helps chickadees live longer 
    First up this week, as part of our series on global equity in science, Contributing Correspondent Vaishnavi Chandrashekhar joins host Sarah Crespi to talk about an initiative in India intended to increase education about early “Indian knowledge systems” amid concerns about homogenization and misinformation.

    Next, producer Kevin McLean climbs a mountain to visit a test bed for intelligence. He met up with Joe Welklin and Vladimir Pravosudov of the University of Nevada, Reno to talk about their research on how memory helps mountain chickadees survive.

    This week’s episode was produced with help from Podigy.

    About the Science Podcast

    Authors: Sarah Crespi; Kevin McLean; Vaishnavi Chandrashekhar
     
    Episode page: https://www.science.org/doi/10.1126/science.zbfmymg
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  • First up this week on the podcast, the latest conservation news with Staff Writer Erik Stokstad. Stokstad and host Sarah Crespi talk about the fate of snow crabs in the Bering Sea, how much we have been overestimating fishing stocks worldwide, and invasive snakes in Guam that bite off more than they can chew.
     
    Next, a fungus takes the wheel. Anand Mishra, a research associate in the department of mechanical and aerospace engineering at Cornell University, discusses a method of integrating electronics with fungal cells in a biohybrid robot. By using the hardy cells from a mushroom instead of the delicate cells of an animal, Mishra and colleagues hope to durably introduce the sensing and signaling capacity of these living organisms into robots.
     
    Finally, the fourth installment of our six-part series on books that look to an optimistic future. This month, host Angela Saini talks with science writer Akshat Rathi about how capitalism might just save us from climate change and his book Climate Capitalism: Winning the Race to Zero Emissions and Solving the Crisis of Our Age.
     
    This week’s episode was produced with help from Podigy.
     
    About the Science Podcast
     
    Authors: Sarah Crespi; Erik Stokstad; Angela Saini
     
    Episode page: https://www.science.org/doi/10.1126/science.zt21ifv
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  • First up this week on the show, uncounted kilometers of fences are strung across the globe. Researchers know they interfere with wildlife migrations and sometimes make finding food and safety difficult for animals. But they don’t know where all these fences are. Freelancer science journalist Christine Peterson joins host Sarah Crespi to discuss how artificial intelligence and aerial photos could help create fence inventories and eventually reopen spaces for native species.
     
    Next, Azizi Seixas, interim chair of the University of Miami Miller School of Medicine’s department of informatics and health data science and a professor in the department of psychiatry and behavioral sciences, discusses his review on decentralized randomized trials. Randomized, controlled trials based in a research center or centers have long been the gold standard for determining the effectiveness of a medical intervention. This week on the podcast, Seixas argues that distributed research designs with home-based measurements and reporting have the potential to speed up research, allow greater participation, and make the results of studies more equitable.
     
    This week’s episode was produced with help from Podigy.
     
    About the Science Podcast
     
    Authors: Sarah Crespi, Christine Peterson
     
    About the Science Podcast: https://www.science.org/content/page/about-science-podcast
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  • First up this week, Deputy News Editors Elizabeth Culotta and Shraddha Chakradhar join host Sarah Crespi to talk about the launch of a new series highlighting the latest in postcolonial science. They cover how researchers around the world, but especially in the Global South, are reckoning with colonial legacies and what is in store for the rest of the series.
     
    Next, producer Meagan Cantwell talks with Mario Fischer-Gödde, a research scientist at the University of Cologne about the origins of the giant asteroid thought to have killed off the dinosaurs 66 million years ago.
     
    This week’s episode was produced with help from Podigy.
    About the Science Podcast 
    Authors: Sarah Crespi, Elizabeth Culotta, Shraddha Chakradhar, Meagan Cantwell
    Episode page: https://www.science.org/doi/10.1126/science.zjugpvu
    About the Science Podcast: https://www.science.org/content/page/about-science-podcast
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  • Researchers debate if humidity makes heat more deadly, and finding excess diabetes cases in Ukrainian people that were born right after the 1930s famine

    First up this week, which is worse: the heat or the humidity? Staff writer Meredith Wadman joins host Sarah Crespi to talk about conflicting reports on the risk of increased mortality when humidity compounds heat, and how to resolve the debate in the field.  
     
    Next, LH Lumey, a professor of epidemiology at the Columbia University Medical Center, discusses what the catastrophe of a famine can teach us about the importance of maternal and fetal health for the long term. His work focuses on records of a 1930s Ukrainian famine painstakingly reconstructed by Ukrainian demographers after being obscured by the former Soviet Union. The famine records combined with newer data show that babies gestated during famine are more likely to acquire type 2 diabetes later in life. 
     
    This week’s episode was produced with help from Podigy.
     
    About the Science Podcast
     
    Authors: Sarah Crespi, Meredith Wadman
      
    Episode page: https://www.science.org/doi/10.1126/science.z6yms94
     
    About the Science Podcast: https://www.science.org/content/page/about-science-podcast
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  • First up this week, we hear about caves on the Moon, a shake-up at Pompeii, and the iron-lined teeth of the Komodo dragon. Reporter Phie Jacobs joins host Sarah Crespi to discuss these news stories and more from our daily newsletter, ScienceAdviser.
     
    Next on the show, electron microscopes allow us to view a world inaccessible to light—at incredible resolution and tiny scales. But bombarding samples with a beam of electrons has downsides. The high-energy electrons used for visualizing minute structures can cause damage to certain materials. Jonathan Peters, a research fellow in the School of Physics at Trinity College Dublin, joins the podcast to talk about a new approach that protects samples while keeping resolution sharp. 
     
    This week’s episode was produced with help from Podigy.
     
    About the Science Podcast
     
    Authors: Sarah Crespi, Phie Jacobs,
     
    Episode page: https://www.science.org/doi/10.1126/science.zeecyfw
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  • Tackling air pollution—indoors and outdoors, how burned-up satellites in the atmosphere could destroy ozone, and the latest in our series of books on a future to look forward to

    First up this week, Science Senior Editor Michael Funk joins host Sarah Crespi to talk about the magazine’s special issue on air pollution. The two discuss the broad scope of air pollution, from home cooking to transmissible disease.
     
    Next, how burned-up satellites may cause pollution problems as megaconstellations take to the skies. Staff Writer Daniel Clery talks about how metals from deorbiting spacecrafts might change the chemistry of the upper atmosphere.
     
    Finally, books host Angela Saini is joined by author Daniela Rus, a roboticist and professor of electrical engineering and computer science at the Massachusetts Institute of Technology. They discuss Rus’s book The Heart and the Chip: Our Bright Future with Robots for this year’s books series that takes an optimistic look at the future.
     
    This week’s episode was produced with help from Podigy.
     
    About the Science Podcast
     
    Authors: Sarah Crespi, Micheal Funk, Angela Saini; Daniel Clery
     
    Episode page: https://www.science.org/doi/10.1126/science.z01x70o
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  • First up this week, Staff Writer Adrian Cho talks with host Sarah Crespi about a fusion company that isn’t aiming for net energy. Instead, it’s looking to sell off the high-energy neutrons from its fusion reactors for different purposes, such as imaging machine parts and generating medical isotopes. In the long run, the company hopes to use money from these neutron-based enterprises for bigger, more energetic reactors that may someday make fusion energy.
    Next, we hear from Tian Du, a Ph.D. candidate in the Dr John and Anne Chong Lab for Functional Genomics at the University of Sydney. She talks about finding antivenom treatments by screening all the genes in the human genome. Her Science Translational Medicine paper focuses on a strong candidate for treating spitting cobra bites, but the technique may prove useful for many other venomous animal bites and stings, from jellyfish to spiders.
    This week’s episode was produced with help from Podigy.
    About the Science Podcast
    Authors: Sarah Crespi, Adrian Cho
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  • Rodenticides are building up inside unintended targets, including birds, mammals, and insects; and bringing bioacoustics and artificial intelligence together for ecology

    First up this week, producer Kevin McLean and freelance science journalist Dina Fine Maron discuss the history of rodent control and how rat poisons are making their way into our ecosystem.
     
    Next on the episode, host Sarah Crespi talks with Jeppe Rasmussen, a postdoctoral fellow in the behavior ecology group at the University of Copenhagen, about why researchers are training artificial intelligence to listen for seals, frogs, and whales.
     
    Additional sound in this segment (some played, some mentioned):
     
    ·      Monk seal noises care of Jeppe Rasmussen
    ·      Frog and crickets from Pond5 
    ·      Lyrebird sounds (Youtube link)
    ·      Cod fish sounds (Fishbase link)
     
    This week’s episode was produced with help from Podigy.
     
    About the Science Podcast
     
    Authors: Kevin McLean, Sarah Crespi, Dina Fine Maron 
     
    Episode page: https://www.science.org/doi/10.1126/science.zq42hy5
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  • First up this week, guest host Kevin McLean talks to freelance writer Andrew Zaleski about recent advancements in the world of synthetic blood. They discuss some of the failed attempts over the past century that led many to abandon the cause altogether, and a promising new option in the works called ErythroMer that is both shelf stable and can work on any blood type.
     
    Next on the episode, producer Zakiya Whatley talks to Aaron Weimann from the University of Cambridge about the evolutionary history of the deadly bacterial pathogen Pseudomonas aeruginosa. They discuss how more than a century’s worth of samples from all over the world contributed to new insights on the emergence and expansion of the pathogen known for its ability to develop antimicrobial resistance.
     
    This week’s episode was produced with help from Podigy.
     
    About the Science Podcast
     
    Authors: Kevin McLean, Andrew Zaleski, Zakiya Whatley
     
    Episode Page: https://www.science.org/doi/10.1126/science.z1jhbqi
     
    About the Science Podcast: https://www.science.org/content/page/about-science-podcast
     
    [Image: Matt Roth, Music: Jeffrey Cook and Nguyen Khoi Nguyen]
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  • Guest host Meagan Cantwell talks to Staff Writer Erik Stokstad about a new weapon against crop-destroying beetles. By making pesticides using RNA, farmers can target pests and their close relatives, leaving other creatures unharmed. 
    Next, freelance producer Katherine Irving talks to hydrologist Craig Brinkerhoff about a recent analysis of ephemeral streams—which are only around temporarily—throughout the United States. Despite their fleeting presence, Brinkerhoff and his colleagues found these streams play a major role in keeping rivers flowing and clean. Brinkerhoff is currently a postdoctoral fellow at Yale University, and completed this work as a Ph.D. student at the University of Massachusetts Amherst.  
    Finally, the next segment in our books series on a future to look forward to. Books host Angela Saini talks with author Rachel O’Dwyer about her recent book Tokens: The Future of Money in the Age of the Platform. They’ll discuss new and old ideas of currency, and what it means to have our identities tied to our money as we move toward a more cashless society.
    This week’s episode was produced with help from Podigy.
    About the Science Podcast
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  • On this week’s show: Scientists are expanding the hunt for habitable exoplanets to bigger worlds, and why improvements in air quality have stagnated in Los Angeles, especially during summer, despite cleaner cars and increased regulations

    Staff Writer Daniel Clery joins producer Meagan Cantwell to talk through the major contenders for habitable exoplanets—from Earth-like rocky planets to water worlds. Preliminary results from two rocky exoplanets have some researchers concerned about whether they will be able to detect atmospheres around planets orbiting turbulent stars.
     
    Next, producer Ariana Remmel talks with Eva Pfannerstill, an atmospheric chemist at the Jülich Research Center, about how volatile organic compounds, mostly from plants, are causing an increase in air pollution during hot days in Los Angeles. 
     
    This week’s episode was produced with help from Podigy.

    This week’s episode was produced with help from Podigy.

    About the Science Podcast
     
    Authors: Daniel Clery; Meagan Cantwell; Arianna Remmel
     
    Episode page: https://www.science.org/doi/10.1126/science.zxi
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  • On this week’s show: Companion animals such as dogs occupy the same environment we do, which can make them good sentinels for human health, and DNA gives clues to ancient Maya rituals and malaria’s global spread

    Contributing Correspondent Andrew Curry joins host Sarah Crespi to discuss two very different studies that used DNA to dig into our past. One study reveals details of child sacrifices in an ancient Maya city. The other story is on the surprising historical reach of malaria, from Belgium to the Himalayas to South America.
     
    Next on the show, using our canine companions to track human health. Courtney Sexton, a postdoctoral research fellow in the Department of Population Health Sciences at the Virginia-Maryland College of Veterinary Medicine, talks about what we can learn from these furry friends that tend to be exposed to many of the same things we are such as pesticides and cleaning chemicals.
     
    Finally, in a sponsored segment from the Science/AAAS Custom Publishing Office, Jackie Oberst, associate editor of custom publishing, interviews professors Miriam Merad and Brian Brown about the evolution of immunology in health care. This segment is sponsored by the Icahn School of Medicine at Mount Sinai.
     
    This week’s episode was produced with help from Podigy.
     
    About the Science Podcast
     
    Authors: Sarah Crespi; Andrew Curry
     
    Episode page: https://www.science.org/doi/10.1126/science.zxgwbqo
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  • Despite not having a known function, cellular “vaults” are on the verge of being harnessed for all kinds of applications, and looking at the evolution of brown fat into a heat-generating organ
     
    First on this week’s show, Managing News Editor John Travis joins host Sarah Crespi to discuss mysterious cellular complexes called “vaults.” First discovered in the 1980s, scientists have yet to uncover the function of these large, common, hollow structures. But now some researchers are looking to use vaults to deliver cancer drugs and viruses for gene therapy.
     
    Next, what can we learn about the evolution of brown fat from opossums? Unlike white fat, which stores energy in many mammals, brown fat cells use ATP to generate heat, helping babies maintain their body temperature and hibernators kick-start their summers. Susanne Keipert, a researcher in the Department of Molecular Biosciences at Stockholm University’s Wenner-Gren Institute, talks about when in evolutionary history brown fat took on this job of burning energy.
     
    Finally, this week we are launching our music refresh! If you are interested in what happened to our music—where it came from and how it’s different (and the same)—stay tuned for a chat with artist Nguyên Khôi Nguyễn.
     
    This week’s episode was produced with help from Podigy.
     
    About the Science Podcast
     
    Authors: Sarah Crespi; John Travis 

    Episode page: https://www.science.org/doi/10.1126/science.zpoy92t
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  • Studying color vision in with children who gain sight later in life, joining a cancer trial doesn’t improve survival odds, and the first in our books series this year

    First on this week’s show, Staff Writer Jennifer Couzin-Frankel joins host Sarah Crespi to discuss the pros and cons of participating in clinical trials. Her story challenges the common thinking that participating in a trial is beneficial—even in the placebo group—for cancer patients.
     
    Next, Lukas Vogelsang, a postdoctoral fellow in the department of brain and cognitive sciences at the Massachusetts Institute of Technology, talks about research into color vision with “late-sighted” kids. Studying children who were born blind and then later gained vision gave researchers new insights into how vision develops in babies and may even help train computers to see better.
     
    Last up on the show is the first in our series of books podcasts on a future to look forward to. Books host Angela Saini talks with author Claire Horn, a researcher based at Dalhousie University’s Health Justice Institute. They discuss the implications of growing babies from fertilized egg to newborn infant—completely outside the body—and Horn’s book Eve: The Disobedient Future of Birth.
     
    This week’s episode was produced with help from Podigy.
     
    About the Science Podcast
     
    Authors: Sarah Crespi; Angela Saini; Jennifer Couzin-Frankel
     
    Episode page: https://www.science.org/doi/10.1126/science.z6gdgb4
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  • A roundup of online news stories featuring animals, and researchers get crows to “count” to four
     
    This week’s show is all animals all the time. First, Online News Editor Dave Grimm joins host Sarah Crespi to discuss stepping on venomous snakes for science, hunting ice age cave bears, and demolishing lizardlike buildings.
     
    Next, producer Kevin McLean talks with Diana Liao, a postdoctoral researcher at the University of Tübingen, about teaching crows to count out loud. They discuss the complexity of this behavior and how, like the famous band, these counting corvids have all the right vocal skills to do it.
     
    This week’s episode was produced with help from Podigy.
     
    About the Science Podcast
     
    Authors: Sarah Crespi; Kevin McLean; David Grimm
     
    Episode page: https://www.science.org/doi/10.1126/science.ztje4j6
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  • On this week’s show: What happens when the body’s own immune system attacks the brain, and how otters’ use of tools expands their diet
     
    First on the show this week, when rogue antibodies attack the brain, patients can show bizarre symptoms—from extreme thirst, to sleep deprivation, to outright psychosis. Contributing Correspondent Richard Stone joins host Sarah Crespi to discuss the hunt for biomarkers and treatments for this cluster of autoimmune disorders that were once mistaken for schizophrenia or even demonic possession.
     
    Next on this episode, producer Katherine Irving talks with Chris Law, an evolutionary biologist at the University of Washington and the University of Texas at Austin, about how sea otters gain energy benefits (and dental benefits) when they use tools to tackle tougher prey such as snails or large clams.
     
    This week’s episode was produced with help from Podigy.
     
    About the Science Podcast
     
    Authors: Sarah Crespi; Richard Stone; Katherine Irving

    Episode page: https://www.science.org/doi/10.1126/science.z4pdg62
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